BR112014030059A2 - formulações farmacêuticas baseadas no genótipo ou fenótipo. - Google Patents
formulações farmacêuticas baseadas no genótipo ou fenótipo.Info
- Publication number
- BR112014030059A2 BR112014030059A2 BR112014030059A BR112014030059A BR112014030059A2 BR 112014030059 A2 BR112014030059 A2 BR 112014030059A2 BR 112014030059 A BR112014030059 A BR 112014030059A BR 112014030059 A BR112014030059 A BR 112014030059A BR 112014030059 A2 BR112014030059 A2 BR 112014030059A2
- Authority
- BR
- Brazil
- Prior art keywords
- genotype
- phenotype
- pharmaceutical formulations
- formulations based
- pharmaceutical
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B5/00—ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Evolutionary Biology (AREA)
- Medical Informatics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Physiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12170401.9 | 2012-06-01 | ||
| EP12170401.9A EP2668945A1 (de) | 2012-06-01 | 2012-06-01 | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| PCT/EP2013/060824 WO2013178565A1 (de) | 2012-06-01 | 2013-05-27 | Genotyp- bzw. phänotyp-basierte arzeimittelformulierungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014030059A2 true BR112014030059A2 (pt) | 2017-07-25 |
| BR112014030059B1 BR112014030059B1 (pt) | 2022-12-06 |
Family
ID=48520964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014030059-3A BR112014030059B1 (pt) | 2012-06-01 | 2013-05-27 | Formulação farmacêutica de combinação em dose fixa compreendendo tamoxifeno e endoxifeno |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US10285958B2 (pt) |
| EP (2) | EP2668945A1 (pt) |
| JP (2) | JP6096289B2 (pt) |
| KR (1) | KR102129043B1 (pt) |
| CN (2) | CN110075097A (pt) |
| AR (2) | AR091234A1 (pt) |
| AU (1) | AU2013269793B2 (pt) |
| BR (1) | BR112014030059B1 (pt) |
| CA (1) | CA2875189C (pt) |
| DK (1) | DK2854789T3 (pt) |
| ES (1) | ES2744306T3 (pt) |
| HK (1) | HK1207296A1 (pt) |
| HU (1) | HUE045699T2 (pt) |
| IL (1) | IL235988B (pt) |
| MX (1) | MX370304B (pt) |
| NZ (1) | NZ702849A (pt) |
| PL (1) | PL2854789T3 (pt) |
| PT (1) | PT2854789T (pt) |
| RU (1) | RU2683260C2 (pt) |
| SA (1) | SA113340607B1 (pt) |
| SG (2) | SG11201407791VA (pt) |
| TW (1) | TWI644666B (pt) |
| WO (1) | WO2013178565A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| US11965206B2 (en) | 2018-12-21 | 2024-04-23 | John Stoddard | Method of dosing a patient with multiple drugs using adjusted phenotypes of CYP450 enzymes |
Family Cites Families (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1317546C (en) | 1985-07-01 | 1993-05-11 | Werner Meier | Pharmaceutical preparations containing mixtures of hydroxy derivatives of vitamin d |
| US6048857A (en) | 1989-10-17 | 2000-04-11 | Ellinwood, Jr.; Everett H. | Dosing method of administering medicaments via inhalation administration |
| US5580728A (en) | 1994-06-17 | 1996-12-03 | Perlin; Mark W. | Method and system for genotyping |
| US6017963A (en) | 1995-11-14 | 2000-01-25 | Euro-Celtique, S.A. | Formulation for intranasal administration |
| US6760708B1 (en) | 1999-08-19 | 2004-07-06 | Dell Products L.P. | Method and system for migrating stored data to a build-to-order computing system |
| WO2001053460A1 (en) | 2000-01-21 | 2001-07-26 | Variagenics, Inc. | Identification of genetic components of drug response |
| US7427480B2 (en) | 2002-03-26 | 2008-09-23 | Perlegen Sciences, Inc. | Life sciences business systems and methods |
| CN1964714B (zh) * | 2003-08-29 | 2011-09-28 | Hdac默克研究有限责任公司 | 辛二酰苯胺异羟肟酸和吉西他滨在制备用于治疗癌症的药物中的用途 |
| US7504214B2 (en) * | 2003-09-19 | 2009-03-17 | Biotheranostics, Inc. | Predicting outcome with tamoxifen in breast cancer |
| DE10345836A1 (de) | 2003-10-02 | 2005-04-21 | Bayer Technology Services Gmbh | Verfahren zur Simulation der Wechselwirkung von chemischen Substanzen mit lebenden Organismen |
| JP4732683B2 (ja) | 2003-12-29 | 2011-07-27 | ユニバーサル・バイオ・リサーチ株式会社 | 標的物質の検出方法 |
| EP1734944B1 (en) | 2004-03-18 | 2012-06-13 | Fondazione IRCCS Istituto Nazionale dei Tumori | 4-oxo-fenretinide, administered alone and in combination with fenretinide, as preventive and therapeutic agent for cancer |
| US7805282B2 (en) | 2004-03-30 | 2010-09-28 | New York University | Process, software arrangement and computer-accessible medium for obtaining information associated with a haplotype |
| DE102004025534A1 (de) | 2004-05-25 | 2005-12-15 | Bayer Technology Services Gmbh | Verfahren zur (zweistufigen) Dosis- und Dosierungsfindung |
| US8024128B2 (en) | 2004-09-07 | 2011-09-20 | Gene Security Network, Inc. | System and method for improving clinical decisions by aggregating, validating and analysing genetic and phenotypic data |
| US8147615B2 (en) | 2004-11-05 | 2012-04-03 | Infineon Technologies Ag | Method of fabricating semiconductor cleaners |
| MX2007014963A (es) | 2005-06-02 | 2008-04-17 | Biovail Lab Int Srl | Composicion de liberacion modificada de al menos una forma de venlafaxina. |
| US20070122824A1 (en) | 2005-09-09 | 2007-05-31 | Tucker Mark R | Method and Kit for Assessing a Patient's Genetic Information, Lifestyle and Environment Conditions, and Providing a Tailored Therapeutic Regime |
| EP1938231A1 (en) | 2005-09-19 | 2008-07-02 | BG Medicine, Inc. | Correlation analysis of biological systems |
| RU2318508C2 (ru) * | 2005-12-28 | 2008-03-10 | Всеволод Иванович Киселев | Фармацевтическая композиция для лечения и профилактики пролиферативных заболеваний молочной железы |
| FR2896896B1 (fr) | 2006-02-02 | 2009-09-25 | Commissariat Energie Atomique | Procede de classification d'evenements ou d'etats en deux etapes |
| DE102006028232A1 (de) | 2006-06-20 | 2007-12-27 | Bayer Technology Services Gmbh | Vorrichtung und Verfahren zur Berechnung und Bereitstellung einer Medikamentendosis |
| ES2665917T3 (es) | 2006-11-21 | 2018-04-30 | Jina Pharmaceuticals Inc. | Endoxifeno para su uso en el tratamiento del cáncer |
| US20090291134A1 (en) | 2006-11-21 | 2009-11-26 | Jina Pharmaceuticals, Inc. | Endoxifen methods and compositions in the treatment of psychiatric and neurodegenerative diseases |
| US8099298B2 (en) | 2007-02-14 | 2012-01-17 | Genelex, Inc | Genetic data analysis and database tools |
| CN102067142A (zh) | 2008-02-26 | 2011-05-18 | 普渡研究基金会 | 用于患者基因分型的方法 |
| WO2009120999A2 (en) * | 2008-03-28 | 2009-10-01 | Olema Pharmaceuticals, Inc. | Use of an endoxifen prodrug for treatment of breast cancer |
| US20100029734A1 (en) * | 2008-05-06 | 2010-02-04 | Ore Pharmaceuticals Inc. | Methods for breast cancer screening and treatment |
| CN102076215A (zh) | 2008-06-30 | 2011-05-25 | 托卡根公司 | 5-氟胞嘧啶制剂及其用途 |
| JP4517312B2 (ja) * | 2008-07-08 | 2010-08-04 | ソニー株式会社 | メモリアクセス制御装置および撮像装置 |
| US20110136913A1 (en) * | 2008-08-19 | 2011-06-09 | Goetz Matthew P | Assessing and treating breast cancer patients |
| US8275442B2 (en) | 2008-09-25 | 2012-09-25 | Zeltiq Aesthetics, Inc. | Treatment planning systems and methods for body contouring applications |
| US7873482B2 (en) | 2008-12-16 | 2011-01-18 | Bruno Stefanon | Diagnostic system for selecting nutrition and pharmacological products for animals |
| US20120088247A1 (en) * | 2009-02-23 | 2012-04-12 | Indian University Research & Technology Corporatio | Materials and methods for treating patients with taxoxifen |
| WO2011072244A1 (en) * | 2009-12-10 | 2011-06-16 | Mount Sinai School Of Medicine Of New York University | Method of treatment of breast cancer with tamoxifen |
| US9372198B2 (en) | 2010-06-17 | 2016-06-21 | Aradigm Corporation | Diagnosis of entry of gastrointestinal contents into respiratory tract of humans and animals |
| RU2611662C2 (ru) * | 2010-08-26 | 2017-02-28 | Ипка Лэборэториз Лимитед | Способы лечения или профилактики тромбообразования или эмболии |
| JP2014518260A (ja) * | 2011-06-27 | 2014-07-28 | アイピーシーエー ラボラトリーズ リミテッド | 抗血栓症化合物 |
| AU2012376214B2 (en) | 2012-04-02 | 2019-02-14 | Berg Llc | Interrogatory cell-based assays and uses thereof |
| EP2668945A1 (de) | 2012-06-01 | 2013-12-04 | Bayer Technology Services GmbH | Genotyp- bzw. Phänotyp-basierte Arzeimittelformulierungen |
| US9417221B2 (en) | 2013-08-27 | 2016-08-16 | International Business Machines Corporation | Food steganography |
-
2012
- 2012-06-01 EP EP12170401.9A patent/EP2668945A1/de not_active Withdrawn
-
2013
- 2013-05-27 PL PL13725157T patent/PL2854789T3/pl unknown
- 2013-05-27 CA CA2875189A patent/CA2875189C/en active Active
- 2013-05-27 KR KR1020147036212A patent/KR102129043B1/ko active IP Right Grant
- 2013-05-27 AU AU2013269793A patent/AU2013269793B2/en active Active
- 2013-05-27 PT PT13725157T patent/PT2854789T/pt unknown
- 2013-05-27 RU RU2014154140A patent/RU2683260C2/ru active
- 2013-05-27 EP EP13725157.5A patent/EP2854789B1/de active Active
- 2013-05-27 NZ NZ702849A patent/NZ702849A/en unknown
- 2013-05-27 US US14/403,823 patent/US10285958B2/en active Active
- 2013-05-27 MX MX2014014596A patent/MX370304B/es active IP Right Grant
- 2013-05-27 CN CN201910317702.5A patent/CN110075097A/zh active Pending
- 2013-05-27 HU HUE13725157A patent/HUE045699T2/hu unknown
- 2013-05-27 CN CN201380040850.8A patent/CN104507464A/zh active Pending
- 2013-05-27 WO PCT/EP2013/060824 patent/WO2013178565A1/de active Application Filing
- 2013-05-27 SG SG11201407791VA patent/SG11201407791VA/en unknown
- 2013-05-27 SG SG10201610072UA patent/SG10201610072UA/en unknown
- 2013-05-27 ES ES13725157T patent/ES2744306T3/es active Active
- 2013-05-27 JP JP2015514441A patent/JP6096289B2/ja active Active
- 2013-05-27 BR BR112014030059-3A patent/BR112014030059B1/pt active IP Right Grant
- 2013-05-27 DK DK13725157.5T patent/DK2854789T3/da active
- 2013-05-31 TW TW102119266A patent/TWI644666B/zh active
- 2013-05-31 AR ARP130101928 patent/AR091234A1/es unknown
- 2013-06-01 SA SA113340607A patent/SA113340607B1/ar unknown
-
2014
- 2014-11-30 IL IL235988A patent/IL235988B/en active IP Right Grant
-
2015
- 2015-08-17 HK HK15107896.3A patent/HK1207296A1/xx unknown
-
2016
- 2016-11-09 JP JP2016219156A patent/JP2017048234A/ja active Pending
-
2017
- 2017-01-31 US US15/420,733 patent/US20170326080A1/en not_active Abandoned
- 2017-06-16 US US15/625,553 patent/US20170326081A1/en not_active Abandoned
-
2020
- 2020-04-30 AR ARP200101246A patent/AR118842A2/es unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B25A | Requested transfer of rights approved |
Owner name: BAYER AKTIENGESELLSCHAFT (DE) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/05/2013, OBSERVADAS AS CONDICOES LEGAIS |