BR112014028413A2 - usos terapêuticos de proteínas do fator de crescimento de fibroblastos 21 . - Google Patents
usos terapêuticos de proteínas do fator de crescimento de fibroblastos 21 .Info
- Publication number
- BR112014028413A2 BR112014028413A2 BR112014028413A BR112014028413A BR112014028413A2 BR 112014028413 A2 BR112014028413 A2 BR 112014028413A2 BR 112014028413 A BR112014028413 A BR 112014028413A BR 112014028413 A BR112014028413 A BR 112014028413A BR 112014028413 A2 BR112014028413 A2 BR 112014028413A2
- Authority
- BR
- Brazil
- Prior art keywords
- growth factor
- fibroblast growth
- therapeutic uses
- factor proteins
- proteins
- Prior art date
Links
- 102000018233 Fibroblast Growth Factor Human genes 0.000 title 1
- 108050007372 Fibroblast Growth Factor Proteins 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261646974P | 2012-05-15 | 2012-05-15 | |
| US201361786939P | 2013-03-15 | 2013-03-15 | |
| PCT/US2013/040275 WO2013173158A1 (en) | 2012-05-15 | 2013-05-09 | Therapeutic uses of fibroblast growth factor 21 proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014028413A2 true BR112014028413A2 (pt) | 2017-11-07 |
Family
ID=48483225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014028413A BR112014028413A2 (pt) | 2012-05-15 | 2013-05-09 | usos terapêuticos de proteínas do fator de crescimento de fibroblastos 21 . |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20150141335A1 (https=) |
| EP (1) | EP2852398A1 (https=) |
| JP (1) | JP2015522539A (https=) |
| KR (1) | KR20150002801A (https=) |
| CN (1) | CN104302311A (https=) |
| AU (1) | AU2013263188A1 (https=) |
| BR (1) | BR112014028413A2 (https=) |
| CA (1) | CA2869320A1 (https=) |
| CL (1) | CL2014002846A1 (https=) |
| CO (1) | CO7131381A2 (https=) |
| EA (1) | EA201491856A1 (https=) |
| HK (1) | HK1202800A1 (https=) |
| IL (1) | IL235482A0 (https=) |
| MA (1) | MA37506B1 (https=) |
| MX (1) | MX2014013913A (https=) |
| PE (1) | PE20142432A1 (https=) |
| PH (1) | PH12014502537A1 (https=) |
| SG (1) | SG11201407655TA (https=) |
| TN (1) | TN2014000409A1 (https=) |
| WO (1) | WO2013173158A1 (https=) |
| ZA (1) | ZA201407532B (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105601748B (zh) | 2011-07-01 | 2021-08-27 | 恩格姆生物制药公司 | 用于代谢病症和疾病治疗的组合物、应用和方法 |
| US9290557B2 (en) | 2012-11-28 | 2016-03-22 | Ngm Biopharmaceuticals, Inc. | Compositions comprising variants and fusions of FGF19 polypeptides |
| HK1214832A1 (zh) | 2012-11-28 | 2016-08-05 | 恩格姆生物制药公司 | 用於代謝病症和疾病治療的組合物和方法 |
| ES2915851T3 (es) | 2012-12-27 | 2022-06-27 | Ngm Biopharmaceuticals Inc | Péptidos quiméricos de FGF19 para usar en el tratamiento de trastornos de ácidos biliares |
| US9273107B2 (en) | 2012-12-27 | 2016-03-01 | Ngm Biopharmaceuticals, Inc. | Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| CA2927592C (en) | 2013-10-28 | 2020-08-18 | Ngm Biopharmaceuticals, Inc. | Fgf-19 variants for treating a fgf-19 dependent cancer or tumor |
| PE20170256A1 (es) | 2014-01-24 | 2017-04-22 | Ngm Biopharmaceuticals Inc | Proteinas de union y sus metodos de uso |
| WO2015183890A2 (en) | 2014-05-28 | 2015-12-03 | Ngm Biopharmaceuticals, Inc. | Methods and compositions for the treatment of metabolic disorders and diseases |
| AU2015277438B2 (en) | 2014-06-16 | 2020-02-27 | Ngm Biopharmaceuticals, Inc. | Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases |
| US10293026B2 (en) | 2014-09-08 | 2019-05-21 | Osaka University | Agent for preventing or treating demyelinating disease |
| RU2729161C2 (ru) | 2014-10-23 | 2020-08-04 | ЭнДжиЭм БАЙОФАРМАСЬЮТИКАЛЗ, ИНК. | Фармацевтические композиции, содержащие варианты пептидов, и способы их применения |
| US10434144B2 (en) | 2014-11-07 | 2019-10-08 | Ngm Biopharmaceuticals, Inc. | Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders |
| US10800843B2 (en) | 2015-07-29 | 2020-10-13 | Ngm Biopharmaceuticals, Inc. | Beta klotho-binding proteins |
| JP6728352B2 (ja) | 2015-11-09 | 2020-07-22 | エヌジーエム バイオファーマシューティカルス，インコーポレーテッド | 胆汁酸に関係した障害の治療方法 |
| CA3034399A1 (en) | 2016-08-26 | 2018-03-01 | Ngm Biopharmaceuticals, Inc. | Methods of treating fibroblast growth factor 19-mediated cancers and tumors |
| CN108324928B (zh) * | 2018-03-05 | 2020-09-08 | 哈尔滨医科大学 | 重组人成纤维细胞生长因子-5在促骨折愈合中的应用 |
| EP3935075A4 (en) | 2019-03-05 | 2023-01-18 | Sunshine Lake Pharma Co., Ltd. | POLYPEPTIDE MOLECULE AND APPLICATION THEREOF |
| CN113728013B (zh) | 2020-01-11 | 2022-06-14 | 北京质肽生物医药科技有限公司 | Glp-1和fgf21的融合蛋白的缀合物 |
| WO2023284822A1 (en) | 2021-07-14 | 2023-01-19 | Beijing Ql Biopharmaceutical Co., Ltd. | Fusion polypeptides for metabolic disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107501407B (zh) * | 2007-03-30 | 2022-03-18 | Ambrx公司 | 经修饰fgf-21多肽和其用途 |
| AR087973A1 (es) * | 2011-10-04 | 2014-04-30 | Lilly Co Eli | Variantes del factor 21 del crecimiento de fibroblastos |
-
2013
- 2013-05-09 MA MA37506A patent/MA37506B1/fr unknown
- 2013-05-09 BR BR112014028413A patent/BR112014028413A2/pt not_active IP Right Cessation
- 2013-05-09 PE PE2014001980A patent/PE20142432A1/es not_active Application Discontinuation
- 2013-05-09 AU AU2013263188A patent/AU2013263188A1/en not_active Abandoned
- 2013-05-09 SG SG11201407655TA patent/SG11201407655TA/en unknown
- 2013-05-09 JP JP2015512695A patent/JP2015522539A/ja not_active Withdrawn
- 2013-05-09 CN CN201380025338.6A patent/CN104302311A/zh active Pending
- 2013-05-09 MX MX2014013913A patent/MX2014013913A/es unknown
- 2013-05-09 EP EP13724685.6A patent/EP2852398A1/en not_active Withdrawn
- 2013-05-09 US US14/399,037 patent/US20150141335A1/en not_active Abandoned
- 2013-05-09 EA EA201491856A patent/EA201491856A1/ru unknown
- 2013-05-09 KR KR1020147031701A patent/KR20150002801A/ko not_active Withdrawn
- 2013-05-09 WO PCT/US2013/040275 patent/WO2013173158A1/en not_active Ceased
- 2013-05-09 HK HK15103356.5A patent/HK1202800A1/xx unknown
- 2013-05-09 CA CA2869320A patent/CA2869320A1/en not_active Abandoned
-
2014
- 2014-09-30 TN TNP2014000409A patent/TN2014000409A1/fr unknown
- 2014-10-16 ZA ZA2014/07532A patent/ZA201407532B/en unknown
- 2014-10-22 CL CL2014002846A patent/CL2014002846A1/es unknown
- 2014-11-03 IL IL235482A patent/IL235482A0/en unknown
- 2014-11-14 PH PH12014502537A patent/PH12014502537A1/en unknown
- 2014-11-14 CO CO14252512A patent/CO7131381A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201407655TA (en) | 2014-12-30 |
| CO7131381A2 (es) | 2014-12-01 |
| CL2014002846A1 (es) | 2015-01-30 |
| CA2869320A1 (en) | 2013-11-21 |
| EA201491856A1 (ru) | 2015-03-31 |
| EP2852398A1 (en) | 2015-04-01 |
| AU2013263188A1 (en) | 2014-10-16 |
| ZA201407532B (en) | 2016-05-25 |
| CN104302311A (zh) | 2015-01-21 |
| HK1202800A1 (en) | 2015-10-09 |
| JP2015522539A (ja) | 2015-08-06 |
| PE20142432A1 (es) | 2015-01-22 |
| PH12014502537A1 (en) | 2015-01-21 |
| MA37506A1 (fr) | 2016-01-29 |
| TN2014000409A1 (en) | 2015-12-21 |
| US20150141335A1 (en) | 2015-05-21 |
| KR20150002801A (ko) | 2015-01-07 |
| MA37506B1 (fr) | 2017-03-31 |
| IL235482A0 (en) | 2014-12-31 |
| MX2014013913A (es) | 2015-02-17 |
| WO2013173158A1 (en) | 2013-11-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |