BR112014028315B1 - Composto, métodos in vitro ou ex vivo para introdução de uma molécula dentro do citosol de uma célula, para obter a morte de uma célula e para expressar uma molécula antigênica ou uma parte da mesma na superfície de uma célula, composição farmacêutica, usos de um composto ou de uma composição e de uma célula ou população de células, e, kit - Google Patents

Composto, métodos in vitro ou ex vivo para introdução de uma molécula dentro do citosol de uma célula, para obter a morte de uma célula e para expressar uma molécula antigênica ou uma parte da mesma na superfície de uma célula, composição farmacêutica, usos de um composto ou de uma composição e de uma célula ou população de células, e, kit Download PDF

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BR112014028315B1
BR112014028315B1 BR112014028315-0A BR112014028315A BR112014028315B1 BR 112014028315 B1 BR112014028315 B1 BR 112014028315B1 BR 112014028315 A BR112014028315 A BR 112014028315A BR 112014028315 B1 BR112014028315 B1 BR 112014028315B1
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compound
cell
cells
molecule
composition
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BR112014028315-0A
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English (en)
Portuguese (pt)
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BR112014028315A2 (pt
Inventor
Kristian Berg
Anders H0Gset
Már Másson
Vivek S. Gaware
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Pci Biotech As
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Publication of BR112014028315B1 publication Critical patent/BR112014028315B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/722Chitin, chitosan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0024Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
    • C08B37/00272-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
    • C08B37/003Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR112014028315-0A 2012-05-15 2013-05-14 Composto, métodos in vitro ou ex vivo para introdução de uma molécula dentro do citosol de uma célula, para obter a morte de uma célula e para expressar uma molécula antigênica ou uma parte da mesma na superfície de uma célula, composição farmacêutica, usos de um composto ou de uma composição e de uma célula ou população de células, e, kit BR112014028315B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1208548.6A GB201208548D0 (en) 2012-05-15 2012-05-15 Compound and method
GB1208548.6 2012-05-15
PCT/EP2013/059968 WO2013189663A1 (en) 2012-05-15 2013-05-14 Conjugate of a photosensitiser and chitosan and uses thereof

Publications (2)

Publication Number Publication Date
BR112014028315A2 BR112014028315A2 (pt) 2017-10-24
BR112014028315B1 true BR112014028315B1 (pt) 2022-02-22

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Application Number Title Priority Date Filing Date
BR112014028315-0A BR112014028315B1 (pt) 2012-05-15 2013-05-14 Composto, métodos in vitro ou ex vivo para introdução de uma molécula dentro do citosol de uma célula, para obter a morte de uma célula e para expressar uma molécula antigênica ou uma parte da mesma na superfície de uma célula, composição farmacêutica, usos de um composto ou de uma composição e de uma célula ou população de células, e, kit

Country Status (23)

Country Link
US (1) US9901636B2 (https=)
EP (1) EP2849791B1 (https=)
JP (1) JP6456284B2 (https=)
KR (2) KR102269861B1 (https=)
CN (1) CN104780941B (https=)
AU (1) AU2013279748B2 (https=)
BR (1) BR112014028315B1 (https=)
CA (1) CA2873259C (https=)
DK (1) DK2849791T3 (https=)
ES (1) ES2682762T3 (https=)
GB (1) GB201208548D0 (https=)
HR (1) HRP20181276T1 (https=)
HU (1) HUE039725T2 (https=)
IN (1) IN2014DN09418A (https=)
MX (1) MX362237B (https=)
NZ (1) NZ630582A (https=)
PL (1) PL2849791T3 (https=)
PT (1) PT2849791T (https=)
RU (1) RU2675830C2 (https=)
SG (1) SG11201407603YA (https=)
SI (1) SI2849791T1 (https=)
WO (1) WO2013189663A1 (https=)
ZA (1) ZA201408406B (https=)

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GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
AU2014390262B2 (en) 2014-04-11 2020-11-26 Pci Biotech As Method of treating melanoma
EP3185901B1 (en) 2014-08-28 2023-10-04 PCI Biotech AS Compound and method
CN104650259A (zh) * 2015-01-23 2015-05-27 广西大学 一种纳米孔壳聚糖四(4-磺酸基苯基)金属卟啉微球及其制备方法和使用方法
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
GB201511159D0 (en) 2015-06-24 2015-08-05 Univ Nottingham Controlled cell delivery vehicle and treatment of tumours
WO2017162918A1 (en) 2016-03-22 2017-09-28 Åbo Akademi University Polysaccharide derivatives as optical brightening agents
KR20190013289A (ko) * 2017-08-01 2019-02-11 순천대학교 산학협력단 수용성 키토산을 포함하는 나노광증감제
GB201801169D0 (en) 2018-01-24 2018-03-07 Pci Biotech As Method
CN108892743A (zh) * 2018-05-28 2018-11-27 南京工业大学 用于光动力抗菌的纳米光敏剂,其制备方法及应用
GB202101726D0 (en) 2021-02-08 2021-03-24 Pci Biotech As Method
CN115399328B (zh) * 2021-05-27 2024-03-22 中国科学院化学研究所 一种多糖基杀菌材料及其制备方法和应用
GB202115451D0 (en) 2021-10-27 2021-12-08 Pci Biotech As Method
CN117285662A (zh) * 2022-06-15 2023-12-26 南京仁为医药科技有限公司 一种壳聚糖双吡啶季铵盐及其制备方法
GB202301312D0 (en) 2023-01-30 2023-03-15 Pci Biotech As Method and product

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GB0018527D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Composition
JP2002241307A (ja) * 2001-02-19 2002-08-28 Yasuhiko Tabata 光増感剤を含有する超音波治療用活性酸素発生剤
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KR101250150B1 (ko) * 2010-10-29 2013-04-04 가톨릭대학교 산학협력단 광역학치료를 위한 고분자-광응답제 접합체 및 이의 제조방법

Also Published As

Publication number Publication date
ZA201408406B (en) 2016-02-24
NZ630582A (en) 2017-02-24
MX2014013516A (es) 2015-11-13
JP2015516496A (ja) 2015-06-11
KR20200085380A (ko) 2020-07-14
CN104780941A (zh) 2015-07-15
WO2013189663A1 (en) 2013-12-27
KR20150013803A (ko) 2015-02-05
BR112014028315A2 (pt) 2017-10-24
PT2849791T (pt) 2018-10-04
CN104780941B (zh) 2019-01-15
HK1203850A1 (en) 2015-11-06
KR102269861B1 (ko) 2021-06-28
RU2014150569A (ru) 2016-07-10
EP2849791B1 (en) 2018-07-04
US20150202293A1 (en) 2015-07-23
GB201208548D0 (en) 2012-06-27
HUE039725T2 (hu) 2019-01-28
HRP20181276T1 (hr) 2018-11-16
RU2675830C2 (ru) 2018-12-25
SI2849791T1 (sl) 2018-10-30
AU2013279748B2 (en) 2018-08-02
PL2849791T3 (pl) 2019-03-29
AU2013279748A1 (en) 2014-11-20
ES2682762T3 (es) 2018-09-21
EP2849791A1 (en) 2015-03-25
JP6456284B2 (ja) 2019-01-23
MX362237B (es) 2019-01-09
CA2873259C (en) 2021-08-03
US9901636B2 (en) 2018-02-27
IN2014DN09418A (https=) 2015-07-17
SG11201407603YA (en) 2014-12-30
DK2849791T3 (en) 2018-08-13
CA2873259A1 (en) 2013-12-27

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