BR112014025306B1 - Processo para produção de uma proteína recombinante em células vegetais com uma parede celular, meio de cultura adequado para promover a secreção e mistura seca do mesmo - Google Patents

Processo para produção de uma proteína recombinante em células vegetais com uma parede celular, meio de cultura adequado para promover a secreção e mistura seca do mesmo Download PDF

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Publication number
BR112014025306B1
BR112014025306B1 BR112014025306-4A BR112014025306A BR112014025306B1 BR 112014025306 B1 BR112014025306 B1 BR 112014025306B1 BR 112014025306 A BR112014025306 A BR 112014025306A BR 112014025306 B1 BR112014025306 B1 BR 112014025306B1
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Brazil
Prior art keywords
concentration
ions
culture medium
medium
cell
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BR112014025306-4A
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English (en)
Portuguese (pt)
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BR112014025306A2 (pt
Inventor
Wolfgang Jost
Mathias Knappenberger
Doreen Claussnitzer
Andreas Schaaf
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eleva GmbH
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Application filed by eleva GmbH filed Critical eleva GmbH
Publication of BR112014025306A2 publication Critical patent/BR112014025306A2/pt
Publication of BR112014025306B1 publication Critical patent/BR112014025306B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/12—Unicellular algae; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
BR112014025306-4A 2012-04-17 2013-04-17 Processo para produção de uma proteína recombinante em células vegetais com uma parede celular, meio de cultura adequado para promover a secreção e mistura seca do mesmo BR112014025306B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12164458.7A EP2653548A1 (de) 2012-04-17 2012-04-17 Verfahren zur Erhöhung der Sekretion rekombinanter Proteine
EP12164458.7 2012-04-17
PCT/EP2013/057956 WO2013156504A1 (de) 2012-04-17 2013-04-17 Verfahren zur erhöhung der sekretion rekombinanter proteine

Publications (2)

Publication Number Publication Date
BR112014025306A2 BR112014025306A2 (pt) 2017-06-20
BR112014025306B1 true BR112014025306B1 (pt) 2021-11-30

Family

ID=48143287

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014025306-4A BR112014025306B1 (pt) 2012-04-17 2013-04-17 Processo para produção de uma proteína recombinante em células vegetais com uma parede celular, meio de cultura adequado para promover a secreção e mistura seca do mesmo

Country Status (19)

Country Link
US (1) US9850513B2 (https=)
EP (2) EP2653548A1 (https=)
JP (1) JP6215305B2 (https=)
KR (1) KR102028738B1 (https=)
CN (1) CN104379750A (https=)
AU (1) AU2013248312B2 (https=)
BR (1) BR112014025306B1 (https=)
CA (1) CA2870587A1 (https=)
DK (1) DK2839012T3 (https=)
ES (1) ES2755973T3 (https=)
HR (1) HRP20191876T1 (https=)
IL (1) IL235052B (https=)
IN (1) IN2014DN08664A (https=)
LT (1) LT2839012T (https=)
MX (1) MX353243B (https=)
PL (1) PL2839012T3 (https=)
PT (1) PT2839012T (https=)
SI (1) SI2839012T1 (https=)
WO (1) WO2013156504A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2729732B2 (ja) 1992-10-05 1998-03-18 新日本製鐵株式会社 底つき容器の製造方法
EP3808854A1 (de) 2019-10-17 2021-04-21 eleva GmbH Verfahren zur gewinnung von material von pflanzenzelloberflächen
MX2022008339A (es) 2020-01-31 2022-08-04 Chugai Pharmaceutical Co Ltd Metodo para producir una composicion que contiene un polipeptido con coloracion suprimida.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63226281A (ja) * 1986-12-26 1988-09-20 Seitai Kinou Riyou Kagakuhin Shinseizou Gijutsu Kenkyu Kumiai 組織培養方法
JP2000245470A (ja) * 1999-02-26 2000-09-12 Noda Inst For Scient Res 植物細胞間液による外来ポリペプチドの製造方法
DE19947290A1 (de) 1999-10-01 2001-04-19 Greenovation Pflanzenbiotechno Verfahren zur Herstellung proteinöser Substanzen
CN1109750C (zh) 2000-08-15 2003-05-28 中国水产科学研究院黄海水产研究所 一种新型低温碱性蛋白酶、制造方法、应用和产生该蛋白酶的微生物
US6872549B2 (en) 2002-03-27 2005-03-29 Immunex Corporation Methods for increasing polypeptide production
CA2671787C (en) * 2008-07-16 2017-04-04 Sumitomo Chemical Company, Limited Methods for producing secreted proteins
US20100035327A1 (en) * 2008-08-11 2010-02-11 Ann Marie Steele Use of rice-derived products in a universal cell culture medium

Also Published As

Publication number Publication date
IL235052A0 (en) 2014-12-31
IL235052B (en) 2019-12-31
PL2839012T3 (pl) 2020-05-18
LT2839012T (lt) 2019-11-25
EP2653548A1 (de) 2013-10-23
ES2755973T3 (es) 2020-04-24
CN104379750A (zh) 2015-02-25
AU2013248312A1 (en) 2014-10-23
DK2839012T3 (da) 2019-10-21
SI2839012T1 (sl) 2019-12-31
IN2014DN08664A (https=) 2015-05-22
US9850513B2 (en) 2017-12-26
MX2014012407A (es) 2015-04-09
AU2013248312B2 (en) 2018-08-30
JP2015514408A (ja) 2015-05-21
WO2013156504A1 (de) 2013-10-24
PT2839012T (pt) 2019-12-05
JP6215305B2 (ja) 2017-10-18
MX353243B (es) 2018-01-05
KR102028738B1 (ko) 2019-10-04
HRP20191876T1 (hr) 2019-12-27
KR20150014454A (ko) 2015-02-06
BR112014025306A2 (pt) 2017-06-20
US20150079632A1 (en) 2015-03-19
CA2870587A1 (en) 2013-10-24
EP2839012B1 (de) 2019-08-28
EP2839012A1 (de) 2015-02-25

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25D Requested change of name of applicant approved

Owner name: ELEVA GMBH (DE)

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/04/2013, OBSERVADAS AS CONDICOES LEGAIS.