BR112014013719A2 - compostos inibidores da lipogênese - Google Patents
compostos inibidores da lipogêneseInfo
- Publication number
- BR112014013719A2 BR112014013719A2 BR112014013719A BR112014013719A BR112014013719A2 BR 112014013719 A2 BR112014013719 A2 BR 112014013719A2 BR 112014013719 A BR112014013719 A BR 112014013719A BR 112014013719 A BR112014013719 A BR 112014013719A BR 112014013719 A2 BR112014013719 A2 BR 112014013719A2
- Authority
- BR
- Brazil
- Prior art keywords
- inhibiting compounds
- represent
- lipogenesis inhibiting
- lipogenesis
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Cosmetics (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
resumo patente de invenção: "compostos inibidores da lipogênese". a presente invenção refere-se à fórmula (i), na qual - se x = nh, então cada um dos r1, r2, r3, r4 representará um átomo de hidrogênio; se x = n, então o núcleo será aromático e r2, r3 , r4 representam átomos de hidrogênio; e r1 = h, halogênio, arila, hetero arila, alcenila ou acetilenila; ou r1, r2, r3 , r4 são definidos, tais como r1 ou r2 ou r3 representa um grupamento metila, e os três outros radicais representam um átomo de hidrogênio.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR1161341A FR2983858B1 (fr) | 2011-12-08 | 2011-12-08 | Nouveaux composes inhibiteurs de la lipogenese |
PCT/EP2012/074891 WO2013083825A1 (fr) | 2011-12-08 | 2012-12-10 | Nouveaux composes inhibiteurs de la lipogenese |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014013719A2 true BR112014013719A2 (pt) | 2017-06-13 |
BR112014013719A8 BR112014013719A8 (pt) | 2017-06-13 |
Family
ID=47324157
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014013719A BR112014013719A8 (pt) | 2011-12-08 | 2012-12-10 | compostos inibidores da lipogênese |
Country Status (13)
Country | Link |
---|---|
US (1) | US9181189B2 (pt) |
EP (1) | EP2788327A1 (pt) |
JP (1) | JP6113744B2 (pt) |
KR (1) | KR20140101834A (pt) |
CN (1) | CN103974937A (pt) |
AU (1) | AU2012350282A1 (pt) |
BR (1) | BR112014013719A8 (pt) |
CA (1) | CA2857973A1 (pt) |
FR (1) | FR2983858B1 (pt) |
HK (1) | HK1197057A1 (pt) |
MX (1) | MX2014006699A (pt) |
RU (1) | RU2014126394A (pt) |
WO (1) | WO2013083825A1 (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITMI20130995A1 (it) | 2013-06-17 | 2014-12-18 | Chemelectiva S R L | Derivati dell'acido retinoico e processo per la loro preparazione |
FR3020951B1 (fr) | 2014-05-16 | 2016-06-17 | Pierre Fabre Dermo-Cosmetique | Association d'un tetrapeptide et d'un glyceryl ester pour le traitement de l'alopecie androgenique. |
FR3026011B1 (fr) * | 2014-09-24 | 2019-07-19 | Greenpharma | Composition contenant au moins un inhibiteur de certaines chimiokines, son procede d'obtention et son utilisation dermocosmetique pharmaceutique |
US11767314B2 (en) | 2018-11-02 | 2023-09-26 | Conopco, Inc. | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3849576A (en) * | 1964-01-29 | 1974-11-19 | Oreal | Process and cosmetic compositions for the treatment of skin and scalp |
DE3534421A1 (de) | 1985-09-27 | 1987-04-02 | Bayer Ag | Verwendung von thienylaminen als leistungsfoerdernde mittel, neues thienylamin |
US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
US5750108A (en) * | 1995-09-18 | 1998-05-12 | Regenix Marketing Systems, Inc. | Hair treatment system and kit for invigorating hair growth |
DE19639818A1 (de) * | 1996-09-27 | 1998-04-02 | Hoechst Ag | Verwendung von 1-Hydroxy-2-pyridonen zur Behandlung der Seborrhoischen Dermatitis |
WO2003087109A1 (en) * | 2002-04-12 | 2003-10-23 | Silbiotec Due S.A. | Medicaments containing glycerophosphoinositol-4-phosphate derivatives |
US20040081672A1 (en) * | 2002-10-25 | 2004-04-29 | Gupta Shyam K. | Niacinamide, niacin, and niacin esters based delivery systems for treating topical disorders of skin and skin aging |
US7300957B1 (en) * | 2006-06-16 | 2007-11-27 | Whewell Christopher J | Skin care compositions |
US8143410B2 (en) | 2006-11-16 | 2012-03-27 | Allergan, Inc. | Kinase inhibitors |
PL2161290T3 (pl) * | 2008-09-09 | 2012-05-31 | Agfa Graphics Nv | Kompozycje utwardzalne radiacyjnie |
FR2940281B1 (fr) * | 2008-12-22 | 2011-04-01 | Fabre Pierre Dermo Cosmetique | Ester de diol et d'acide gras polyinsature comme agent anti-acne |
FR2954124B1 (fr) * | 2009-12-18 | 2012-04-06 | Fabre Pierre Dermo Cosmetique | Utilisation du 2,3-dihydroxypropyl dodecanoate pour le traitement de la seborrhee |
-
2011
- 2011-12-08 FR FR1161341A patent/FR2983858B1/fr not_active Expired - Fee Related
-
2012
- 2012-12-10 US US14/363,289 patent/US9181189B2/en not_active Expired - Fee Related
- 2012-12-10 RU RU2014126394A patent/RU2014126394A/ru not_active Application Discontinuation
- 2012-12-10 MX MX2014006699A patent/MX2014006699A/es unknown
- 2012-12-10 WO PCT/EP2012/074891 patent/WO2013083825A1/fr active Application Filing
- 2012-12-10 AU AU2012350282A patent/AU2012350282A1/en not_active Abandoned
- 2012-12-10 BR BR112014013719A patent/BR112014013719A8/pt not_active IP Right Cessation
- 2012-12-10 CN CN201280059828.3A patent/CN103974937A/zh active Pending
- 2012-12-10 EP EP12798298.1A patent/EP2788327A1/fr not_active Withdrawn
- 2012-12-10 JP JP2014545301A patent/JP6113744B2/ja not_active Expired - Fee Related
- 2012-12-10 CA CA2857973A patent/CA2857973A1/fr not_active Abandoned
- 2012-12-10 KR KR1020147018421A patent/KR20140101834A/ko not_active Application Discontinuation
-
2014
- 2014-10-14 HK HK14110259A patent/HK1197057A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP6113744B2 (ja) | 2017-04-12 |
RU2014126394A (ru) | 2016-01-27 |
WO2013083825A1 (fr) | 2013-06-13 |
AU2012350282A1 (en) | 2014-06-19 |
MX2014006699A (es) | 2014-07-09 |
KR20140101834A (ko) | 2014-08-20 |
CN103974937A (zh) | 2014-08-06 |
BR112014013719A8 (pt) | 2017-06-13 |
HK1197057A1 (en) | 2015-01-02 |
JP2015502950A (ja) | 2015-01-29 |
US20140315950A1 (en) | 2014-10-23 |
EP2788327A1 (fr) | 2014-10-15 |
FR2983858B1 (fr) | 2014-01-03 |
FR2983858A1 (fr) | 2013-06-14 |
CA2857973A1 (fr) | 2013-06-13 |
US9181189B2 (en) | 2015-11-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1124357T1 (el) | Προσδιορισμος ανισορροπιας αλληλουχιας νουκλεϊκων οξεων | |
CY1117157T1 (el) | Υποκατεστημενο παραγωγο ισοκινολινης | |
BR112014006660A2 (pt) | novos derivados de dihidroquinolina-2-ona bicíclicos | |
BR112013001341A2 (pt) | compostos de pirimidina como inibidores de proteínas quinases ikk épsilon e/ou tbk-1, processo para a preparação dos mesmos e suas composições farmacêuticas | |
CY1124537T1 (el) | Παραγωγο πυριδονης που εχει τετραϋδροπυρανυλ μεθυλ ομαδα | |
BR122019003178B1 (pt) | método de controle de pestes | |
CY1114452T1 (el) | Ενωσεις πυρρολιου | |
MY177250A (en) | Novel nicotinamide derivative or salt thereof | |
CY1123154T1 (el) | Παραγοντας ενισχυσης της επιδρασης αποκαταστασης μετα απο νευρικη βλαβη που περιλαμβανει ενα παραγωγο αλκυλαιθερα ή ενα αλας αυτου | |
BR112014010813A2 (pt) | n-(tetrazol-5-il)-aril-carboxamidas e n-(triazol-5-il)-aril-carboxamidas substituídas em 5-fenilo e sua utilização como herbicidas | |
BR112015009777A2 (pt) | derivado de amina ou sal do mesmo | |
BR112013018732A2 (pt) | novos derivados de amida de aril-benzocicloalquila | |
BR112015023829A2 (pt) | composto de amidina e seu uso | |
BR112015020281A2 (pt) | composto heterocíclico fundido e suas aplicações no controle de pragas | |
BR112015015275A2 (pt) | composto heterocíclico substituído por halogênio | |
BR112016002638A2 (pt) | novos aza-oxo-indóis para o tratamento e profilaxia de infecção pelo virus sincicial respiratório | |
BR112014013719A8 (pt) | compostos inibidores da lipogênese | |
CY1117026T1 (el) | Ετεροκυκλικες ενωσεις για αντιμετωπιση ή προληψη διαταραχων που προκαλουνται απο μειωμενη νευροδιαβιβαση σεροτονινης, νορεπινεφρινης ή ντοπαμινης | |
CU20100157A7 (es) | Nuevos derivados dihidroindolonas, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
BR112015020834A2 (pt) | novos derivados hidroquinolina-2-ona como inibidores de aldosterona sintetase (cyp1 1 b2 ou cyp1 1 b1) | |
BR112014030474A2 (pt) | novos compostos bicíclicos de tiofenilamida | |
BR112015028871A2 (pt) | novos compostos de 3,4-dihidro-2h-isoquinolina-1-ona e 2,3-dihidro-isoindol-1-ona | |
BR112015000392A2 (pt) | novos indazóis para o tratamento e profilaxia da infecção por vírus sincicial respiratório | |
BR112014031969A2 (pt) | derivados de pirimidinona como agentes antimaláricos | |
BRPI0518998A2 (pt) | âmega-feniloctanamidas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2494 DE 23-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
|
B350 | Update of information on the portal [chapter 15.35 patent gazette] |