BR112014011197A2 - terapia combinada para o câncer ovariano - Google Patents

terapia combinada para o câncer ovariano

Info

Publication number
BR112014011197A2
BR112014011197A2 BR112014011197A BR112014011197A BR112014011197A2 BR 112014011197 A2 BR112014011197 A2 BR 112014011197A2 BR 112014011197 A BR112014011197 A BR 112014011197A BR 112014011197 A BR112014011197 A BR 112014011197A BR 112014011197 A2 BR112014011197 A2 BR 112014011197A2
Authority
BR
Brazil
Prior art keywords
ovarian cancer
combination therapy
combination
ylamine
gemcitabine
Prior art date
Application number
BR112014011197A
Other languages
English (en)
Inventor
Michael Chan Edward
Frank Stancato Louis
Elizabeth Pratt Susan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR112014011197A2 publication Critical patent/BR112014011197A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

resumo patente de invenção: "terapia combinada para o câncer ovariano". a presente invenção refere-se a um método para o tratamento do câncer ovariano em um mamífero em necessidade de tal tratamento, que compreendende a administração de uma quantidade eficaz de uma combinação de gemcitabina, de cisplatina ou de carboplatina, e 5-[2-terc-butil-5-(4-fluoro-fenil)-1h-imidazol-4-il]-3-(2,2-dimetil-propil)-3h-imidazo[4,5-b]piridin-2-ilamina.
BR112014011197A 2011-11-11 2012-10-31 terapia combinada para o câncer ovariano BR112014011197A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161558582P 2011-11-11 2011-11-11
PCT/US2012/062634 WO2013070460A1 (en) 2011-11-11 2012-10-31 Combination therapy for ovarian cancer

Publications (1)

Publication Number Publication Date
BR112014011197A2 true BR112014011197A2 (pt) 2017-04-25

Family

ID=47146746

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014011197A BR112014011197A2 (pt) 2011-11-11 2012-10-31 terapia combinada para o câncer ovariano

Country Status (30)

Country Link
US (1) US9844529B2 (pt)
EP (1) EP2780011B1 (pt)
JP (1) JP6055481B2 (pt)
KR (1) KR101647569B1 (pt)
CN (1) CN103917233B (pt)
AP (1) AP3881A (pt)
AU (1) AU2012336154B2 (pt)
BR (1) BR112014011197A2 (pt)
CA (1) CA2850559C (pt)
CR (1) CR20140211A (pt)
CY (1) CY1120315T1 (pt)
DK (1) DK2780011T3 (pt)
DO (1) DOP2014000100A (pt)
EA (1) EA026297B1 (pt)
ES (1) ES2671730T3 (pt)
HR (1) HRP20180875T1 (pt)
HU (1) HUE037928T2 (pt)
IL (1) IL232479A0 (pt)
LT (1) LT2780011T (pt)
ME (1) ME03035B (pt)
MX (1) MX2014005698A (pt)
MY (1) MY168927A (pt)
PL (1) PL2780011T3 (pt)
PT (1) PT2780011T (pt)
RS (1) RS57256B1 (pt)
SG (1) SG11201401795XA (pt)
SI (1) SI2780011T1 (pt)
TN (1) TN2014000150A1 (pt)
WO (1) WO2013070460A1 (pt)
ZA (1) ZA201403159B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015154064A2 (en) 2014-04-04 2015-10-08 Del Mar Pharmaceuticals Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
HRP20221196T1 (hr) 2017-10-05 2022-12-09 Fulcrum Therapeutics, Inc. Inhibitori p38 kinaze smanjuju ekspresiju dux4 i nizvodnih gena u cilju liječenja fshd
US10342786B2 (en) 2017-10-05 2019-07-09 Fulcrum Therapeutics, Inc. P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9916735A (pt) * 1998-12-31 2001-09-25 Sugen Inc Compostos de 3-heteroarilidenil-2-indolinona para a modulação da atividade das cinases protéicas e para uso na quimioterapia do cancêr
TWI332003B (en) * 2004-01-30 2010-10-21 Lilly Co Eli Kinase inhibitors

Also Published As

Publication number Publication date
ZA201403159B (en) 2017-11-29
PT2780011T (pt) 2018-05-14
WO2013070460A1 (en) 2013-05-16
CY1120315T1 (el) 2019-07-10
EP2780011B1 (en) 2018-04-11
DOP2014000100A (es) 2014-06-30
AU2012336154A1 (en) 2014-04-17
CR20140211A (es) 2014-06-20
MX2014005698A (es) 2014-08-21
EA201490766A1 (ru) 2014-08-29
CN103917233B (zh) 2018-11-16
JP2014533270A (ja) 2014-12-11
JP6055481B2 (ja) 2016-12-27
HRP20180875T1 (hr) 2018-07-13
CA2850559C (en) 2016-11-29
AP3881A (en) 2016-10-31
EP2780011A1 (en) 2014-09-24
TN2014000150A1 (en) 2015-09-30
CN103917233A (zh) 2014-07-09
ES2671730T3 (es) 2018-06-08
NZ623622A (en) 2015-07-31
KR20140083010A (ko) 2014-07-03
IL232479A0 (en) 2014-06-30
DK2780011T3 (en) 2018-05-28
CA2850559A1 (en) 2013-05-16
HUE037928T2 (hu) 2018-09-28
LT2780011T (lt) 2018-05-10
PL2780011T3 (pl) 2018-08-31
EA026297B1 (ru) 2017-03-31
MY168927A (en) 2019-01-08
AP2014007631A0 (en) 2014-05-31
RS57256B1 (sr) 2018-08-31
SG11201401795XA (en) 2014-09-26
US9844529B2 (en) 2017-12-19
ME03035B (me) 2018-10-20
KR101647569B1 (ko) 2016-08-10
SI2780011T1 (en) 2018-07-31
AU2012336154B2 (en) 2017-01-12
US20140302174A1 (en) 2014-10-09

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2486 DE 28-08-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]