BR112014010696A2 - método para identificar uma molécula de analito em uma amostra biológica, sensor para capturar um analito de interesse de uma amostra biológica, e, detector - Google Patents

método para identificar uma molécula de analito em uma amostra biológica, sensor para capturar um analito de interesse de uma amostra biológica, e, detector

Info

Publication number
BR112014010696A2
BR112014010696A2 BR112014010696A BR112014010696A BR112014010696A2 BR 112014010696 A2 BR112014010696 A2 BR 112014010696A2 BR 112014010696 A BR112014010696 A BR 112014010696A BR 112014010696 A BR112014010696 A BR 112014010696A BR 112014010696 A2 BR112014010696 A2 BR 112014010696A2
Authority
BR
Brazil
Prior art keywords
biological sample
analyte
capture
interest
identify
Prior art date
Application number
BR112014010696A
Other languages
English (en)
Portuguese (pt)
Inventor
Lynn Brosseau Christa
Michael Blackburn Jonathan
Evans Michael
Krishnan Sriram
Original Assignee
Univ Cape Town
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Cape Town filed Critical Univ Cape Town
Publication of BR112014010696A2 publication Critical patent/BR112014010696A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/553—Metal or metal coated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3517—Marker; Tag
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/10—Applications; Uses in screening processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2610/00—Assays involving self-assembled monolayers [SAMs]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Inorganic Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR112014010696A 2011-11-02 2012-11-02 método para identificar uma molécula de analito em uma amostra biológica, sensor para capturar um analito de interesse de uma amostra biológica, e, detector BR112014010696A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA201108016 2011-11-02
PCT/IB2012/056108 WO2013065016A1 (en) 2011-11-02 2012-11-02 A method of detecting and/or quantifying an analyte in a biological sample

Publications (1)

Publication Number Publication Date
BR112014010696A2 true BR112014010696A2 (pt) 2017-04-25

Family

ID=47222168

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014010696A BR112014010696A2 (pt) 2011-11-02 2012-11-02 método para identificar uma molécula de analito em uma amostra biológica, sensor para capturar um analito de interesse de uma amostra biológica, e, detector

Country Status (8)

Country Link
US (1) US9518986B2 (https=)
EP (1) EP2773958B1 (https=)
CN (1) CN104380105B (https=)
BR (1) BR112014010696A2 (https=)
DK (1) DK2773958T3 (https=)
IN (1) IN2014KN01168A (https=)
WO (1) WO2013065016A1 (https=)
ZA (1) ZA201403386B (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10422792B2 (en) * 2014-03-19 2019-09-24 The Regents Of The University Of Colorado Binding detection using liquid crystal
CA2976963A1 (en) * 2015-02-19 2016-08-25 Ionica Sciences Reagents and methods for detecting infectious diseases
CN105510411B (zh) * 2015-09-14 2018-05-08 陕西师范大学 基于细胞与微电极的相互作用实现单一癌细胞的检测方法
DE102015220414A1 (de) * 2015-10-20 2017-04-20 Robert Bosch Gmbh Propofolsensor zur Messung einer Narkosetiefe
CN105277527A (zh) * 2015-10-29 2016-01-27 江南大学 一种基于拉曼信标分子编码银@金核壳纳米粒子的真菌毒素双重检测方法
KR101816521B1 (ko) * 2016-01-28 2018-01-09 광주과학기술원 삽입제를 이용한 국소표면플라즈몬공명 기반 고감도 압타머 센서
US10103357B2 (en) 2016-02-17 2018-10-16 The Curators Of The University Of Missouri Fabrication of multilayer nanograting structures
CN109791546A (zh) * 2016-10-28 2019-05-21 惠普发展公司有限责任合伙企业 目标类别特征模型
KR101923196B1 (ko) * 2017-09-25 2018-11-28 주식회사 엠디엡투스 Cfp10에 특이적으로 결합하는 dna 압타머 및 이의 용도
WO2019126182A1 (en) * 2017-12-18 2019-06-27 The University Of Memphis Research Foundation Compositions and methods for the detection and molecular profiling of membrane bound vesicles
TWI686599B (zh) * 2018-05-24 2020-03-01 國立清華大學 塵蟎抗原檢測系統及方法
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
WO2020100159A1 (en) * 2018-11-13 2020-05-22 Translational Health Science And Technology Institute A novel aptamer and an electrochemical biosensor for the rapid detection and diagnosis of tuberculous meningitis
WO2020132074A1 (en) 2018-12-18 2020-06-25 The University Of Memphis Research Foundation Compositions and methods for the detection and molecular profiling of membrane bound vesicles
TWI693403B (zh) * 2019-01-17 2020-05-11 逢甲大學 免疫檢測方法
EP3953686A4 (en) * 2019-04-09 2022-12-21 Agency for Science, Technology and Research Label-free detection of mycobacteria using surface enhanced raman spectroscopy
CN110907643A (zh) * 2019-12-02 2020-03-24 中国科学院重庆绿色智能技术研究院 一种大肠杆菌检测芯片的制备方法及检测芯片
CN115836131A (zh) * 2020-05-29 2023-03-21 索莫纳斯科技有限公司 一种丙泊酚传感器
TWI759776B (zh) * 2020-06-22 2022-04-01 淡江大學 檢測基板、拉曼光譜檢測系統及拉曼光譜檢測方法
TW202225689A (zh) * 2020-09-24 2022-07-01 美商創科精密醫學公司 用於偵測病原體之系統、裝置及方法
CN112240881A (zh) * 2020-09-30 2021-01-19 合肥国研汉因检测科技有限公司 使用拉曼光谱法快速检测痕量芬太尼的方法
CN112986212B (zh) * 2021-03-10 2023-01-17 中国人民解放军海军军医大学 一种g-四链体核酸适配体与小分子相互作用的研究方法
CN114577754A (zh) * 2021-12-24 2022-06-03 天津大学 基于适体变构效应的微型光纤表面等离子共振传感器
CN115711873B (zh) * 2022-11-09 2024-05-28 清华大学 一种利用sers文件卡片进行定量分析的方法
CN117054389A (zh) * 2023-07-13 2023-11-14 淮安市第五人民医院 一种用于快速鉴定胃部幽门螺旋杆菌感染的方法

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376556A (en) 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
EP0786469B1 (en) 1990-06-11 2006-03-01 Gilead Sciences, Inc. Methods of use of nucleic acid ligands
EP0598003B1 (en) 1991-07-22 1999-02-10 Kloehn Instruments, Ltd. Substrate for surface-enhanced analytical procedures, and substrates prepared for specific procedures
JP2965502B2 (ja) 1996-02-20 1999-10-18 株式会社京都第一科学 表面増強ラマン散乱測定による分析方法
GB9810865D0 (en) 1998-05-20 1998-07-22 Zeneca Ltd Nucleic acid sequence identification
ATE419528T1 (de) 1999-04-28 2009-01-15 Eidgenoess Tech Hochschule Polyionische beschichtungen für analytische und sensor-vorrichtungen
PT1226422E (pt) 1999-10-06 2008-03-04 Oxonica Inc Nanopartículas compósitas activas em espectroscopia intensificada por superfície
DE10050632A1 (de) 2000-10-12 2002-04-18 Stiftung Caesar Verfahren zum Nachweis biologischer Moleküle
US7238477B2 (en) 2001-09-24 2007-07-03 Intel Corporation Methods to increase nucleotide signals by Raman scattering
US7807348B2 (en) 2002-03-20 2010-10-05 Wisconsin Alumni Research Foundation Optical imaging of nanostructured substrates
US7361313B2 (en) 2003-02-18 2008-04-22 Intel Corporation Methods for uniform metal impregnation into a nanoporous material
US7192703B2 (en) 2003-02-14 2007-03-20 Intel Corporation, Inc. Biomolecule analysis by rolling circle amplification and SERS detection
US20050148100A1 (en) 2003-12-30 2005-07-07 Intel Corporation Methods and devices for using Raman-active probe constructs to assay biological samples
US7351591B2 (en) 2004-03-30 2008-04-01 Intel Corporation Surface modification of metals for biomolecule detection using surface enhanced Raman scattering (SERS)
DK1749122T3 (da) 2004-04-23 2019-11-11 Becton Dickinson Co Overfladeforbedrede spektroskopi-aktive kompositnanopartikler
CN101014729A (zh) 2004-06-07 2007-08-08 格莱风分析有限责任公司 制造用于sers的基底表面的系统和方法以及使用上述系统和方法的设备
CA2586197C (en) 2004-11-04 2012-08-14 Mesophotonics Limited Metal nano-void photonic crystal for enhanced raman spectroscopy
US7485471B1 (en) 2004-12-17 2009-02-03 Intel Corporation Detection of enhanced multiplex signals by surface enhanced Raman spectroscopy
US7355704B2 (en) 2005-06-13 2008-04-08 Solaris Nanosciences, Inc. Chemical and biological sensing using metallic particles in amplifying and absorbing media
US20070134815A1 (en) 2005-07-11 2007-06-14 Danielle Chamberlin Sensitivity enhancement of POCT devices using gold and silver nanoparticles on substrates containing nanostructures or nanoparticles that interact with labeling particles
US7651863B2 (en) 2005-07-14 2010-01-26 3M Innovative Properties Company Surface-enhanced spectroscopic method, flexible structured substrate, and method of making the same
JP2009523406A (ja) 2005-11-15 2009-06-25 オクソニカ・インコーポレーテッド 生体剤（ｂｉｏａｇｅｎｔｓ）の検出のためのＳＥＲＳに基づく方法
GB0524580D0 (en) * 2005-12-01 2006-01-11 Sphere Medical Ltd Sensor
GB0606088D0 (en) 2006-03-27 2006-05-03 E2V Biosensors Ltd Improved serrs substrate
ES2635272T3 (es) 2007-03-20 2017-10-03 Becton, Dickinson And Company Ensayo que usa partículas activas en espectroscopia Raman potenciada en superficie (SERS)
US8017408B2 (en) 2007-04-27 2011-09-13 The Regents Of The University Of California Device and methods of detection of airborne agents
KR100892629B1 (ko) 2007-06-29 2009-04-08 한국과학기술원 표면 증강 라만 분광용 광 센서
JP2009031023A (ja) 2007-07-25 2009-02-12 Keio Gijuku 表面増強ラマン分光分析用基板の作成方法、マイクロｔａｓの製造方法、及び、マイクロｔａｓ
US20100055803A1 (en) 2008-08-29 2010-03-04 Kwangyeol Lee Method and apparatus for detecting molecules
US8947657B2 (en) * 2008-09-08 2015-02-03 Lawrence Livermore National Security, Llc Methods for isolation and viability assessment of biological organisms
US20100136551A1 (en) * 2008-10-10 2010-06-03 Hansang Cho Microfluidic platform and related methods and systems
CA2783788C (en) * 2009-12-11 2015-02-10 Korea Research Institute Of Chemical Technology Dimeric core-shell nanostructure labeled with raman active molecule localized at interparticle junction, use thereof, and method for preparing the same
TWI487910B (zh) * 2010-09-07 2015-06-11 國立成功大學 倒多角錐陣列型免標定病毒檢測基板、系統及方法

Also Published As

Publication number Publication date
US20140302492A1 (en) 2014-10-09
EP2773958B1 (en) 2017-11-29
IN2014KN01168A (https=) 2015-10-16
ZA201403386B (en) 2016-02-24
CN104380105B (zh) 2017-04-12
EP2773958A1 (en) 2014-09-10
US9518986B2 (en) 2016-12-13
WO2013065016A1 (en) 2013-05-10
CN104380105A (zh) 2015-02-25
DK2773958T3 (en) 2018-03-12

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements
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