BR112014008425A2 - composição para o uso na promoção de angiogênese intestinal e de absorção de nutriente e de tolerância a alimentação enteral e/ou na prevenção e/ou no tratamento de inflamação intestinal e/ou na recuperação após a lesão e a cirurgia intestinal - Google Patents

composição para o uso na promoção de angiogênese intestinal e de absorção de nutriente e de tolerância a alimentação enteral e/ou na prevenção e/ou no tratamento de inflamação intestinal e/ou na recuperação após a lesão e a cirurgia intestinal

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Publication number
BR112014008425A2
BR112014008425A2 BR112014008425A BR112014008425A BR112014008425A2 BR 112014008425 A2 BR112014008425 A2 BR 112014008425A2 BR 112014008425 A BR112014008425 A BR 112014008425A BR 112014008425 A BR112014008425 A BR 112014008425A BR 112014008425 A2 BR112014008425 A2 BR 112014008425A2
Authority
BR
Brazil
Prior art keywords
intestinal
composition
injury
tolerance
recovery
Prior art date
Application number
BR112014008425A
Other languages
English (en)
Inventor
Garcia-Rodenas Clara
Sprenger Norbert
Original Assignee
Nestec Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47010618&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112014008425(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nestec Sa filed Critical Nestec Sa
Publication of BR112014008425A2 publication Critical patent/BR112014008425A2/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21Addition of substantially indigestible substances, e.g. dietary fibres
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/30Dietetic or nutritional methods, e.g. for losing weight
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016Disaccharides, e.g. lactose, lactulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23DEDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00Other edible oils or fats, e.g. shortenings, cooking oils
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pediatric Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

resumo patente de invenção: "composição para o uso na promoção de angiogênese intestinal e de absorção de nutriente e de tolerância a alimentação enteral e/ou na prevenção e/ou no tratamento de inflamação intestinal e/ou na recuperação após a lesão e a cirurgia intestinal". a presente invenção revela uma composição compreendendo pelo menos um ácido graxo poli-insaturado de cadeia longa, pelo menos um probiótico e uma mistura de oligossacarídeos, a dita mistura contendo pelo menos um oligossacarídeo n-acetilado, pelo menos um oligossacarídeo sialilado e pelo menos um oligossacarídeo neutro, para o uso na promoção de angiogênese intestinal e de absorção de nutriente e de tolerância à alimentação enteral e/ou na prevenção e/ou no tratamento de inflamação intestinal, tais como enterocólise necrosante, e/ou na recuperação após a lesão e/ou a cirurgia intestinal. essa composição é particularmente adaptada para o uso em crianças, crianças notadamente prematuras. 20975901v1 1/1 20975901v1
BR112014008425A 2011-10-18 2012-10-15 composição para o uso na promoção de angiogênese intestinal e de absorção de nutriente e de tolerância a alimentação enteral e/ou na prevenção e/ou no tratamento de inflamação intestinal e/ou na recuperação após a lesão e a cirurgia intestinal BR112014008425A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11185606 2011-10-18
PCT/EP2012/070359 WO2013057062A1 (en) 2011-10-18 2012-10-15 Composition for use in the promotion of intestinal angiogenesis and of nutrient absorption and of enteral feeding tolerance and/or in the prevention and/or treatment of intestinal inflammation and/or in the recovery after intestinal injury and surgery

Publications (1)

Publication Number Publication Date
BR112014008425A2 true BR112014008425A2 (pt) 2017-04-11

Family

ID=47010618

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014008425A BR112014008425A2 (pt) 2011-10-18 2012-10-15 composição para o uso na promoção de angiogênese intestinal e de absorção de nutriente e de tolerância a alimentação enteral e/ou na prevenção e/ou no tratamento de inflamação intestinal e/ou na recuperação após a lesão e a cirurgia intestinal

Country Status (10)

Country Link
US (1) US20140286908A1 (pt)
EP (1) EP2768311B1 (pt)
CN (1) CN103889239A (pt)
AU (1) AU2012324985B2 (pt)
BR (1) BR112014008425A2 (pt)
CL (1) CL2014000791A1 (pt)
ES (1) ES2666491T3 (pt)
MX (1) MX2014004719A (pt)
RU (1) RU2624233C2 (pt)
WO (1) WO2013057062A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2451462T3 (en) 2009-07-06 2017-12-11 Children's Hospital Medical Center Inhibition of inflammation with milk oligosaccharides
MX338174B (es) 2010-12-31 2016-04-06 Abbott Lab Metodos para reducir la incidencia de la tension oxidativa al usar los oligosacaridos de leche humana, la vitamina c y los agentes antiinflamatorios.
US9539269B2 (en) 2010-12-31 2017-01-10 Abbott Laboratories Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides
CA2842672A1 (en) 2011-07-22 2013-01-31 Abbott Laboratories Galactooligosaccharides for preventing injury and/or promoting healing of the gastrointestinal tract
SG2014013478A (en) 2011-08-29 2014-05-29 Abbott Lab Human milk oligosaccharides for preventing injury and/or promoting healing of the gastrointestinal tract
CN103250814B (zh) * 2013-06-03 2014-11-05 山东三星玉米产业科技有限公司 一种食用调和油及其制备方法
MX2016006220A (es) 2013-11-15 2016-08-08 Nestec Sa Composiciones para usar en la prevencion o tratamiento de la enterocolitis necrotizante en infantes y niños pequeños nacidos por cesarea.
MX2016006060A (es) * 2013-11-15 2016-08-03 Nestec Sa Composiciones para usar en la prevencion o tratamiento de la enterocolitis necrotizante en infantes y niños pequeños.
US11135232B2 (en) 2013-11-15 2021-10-05 Societe Des Produits Nestle S.A. Compositions for use in the prevention or treatment of necrotizing enterocolitis in infants and young children
RU2717339C2 (ru) * 2013-12-13 2020-03-23 Сосьете Де Продюи Нестле С.А. Применение содержащей сладкую молочную сыворотку детской смеси для обеспечения постнатального развития нервной системы желудочно-кишечного тракта младенца и формирования функций кишечника, которыми она управляет
EP3082473A2 (en) * 2013-12-19 2016-10-26 Nestec S.A. Nutritional composition to reduce metabolic stress in infants
US10857167B2 (en) * 2015-04-28 2020-12-08 Children's Hospital Medical Center Use of oligosaccharide compositions to enhance weight gain
AU2017307455B2 (en) * 2016-08-04 2023-07-06 Société des Produits Nestlé S.A. Nutritional compositions with 2FL and LNnT for use in preventing and/or treating non-rotavirus diarrhea by acting on the gut microbiota dysbiosis
EP3661371A1 (en) * 2017-08-04 2020-06-10 Société des Produits Nestlé S.A. Probiotic bacteria preconditioned in a gos-containing medium and use thereof
WO2019122178A1 (en) * 2017-12-21 2019-06-27 Societe Des Produits Nestle S.A. Compositions comprising at least on n-acetylated and at least one fucosylated oligosaccharide for use in the promotion of digestive capacity in infants and young children
CN111479573B (zh) * 2017-12-21 2024-05-24 雀巢产品有限公司 用于促进肠道肌肉生长和发育以及相关联的肠道能动性的组合物
CN110038020A (zh) * 2019-04-23 2019-07-23 河南省农业科学院 唾液酸模拟物在制备抑制巨噬细胞感染或激活状态下所引起炎症的药物中的应用
CN110839698A (zh) * 2019-11-29 2020-02-28 内蒙古伊利实业集团股份有限公司 一种组合物及其食品用途
MX2023005670A (es) 2020-12-04 2023-05-26 Nestle Sa Composicion para infantes prematuros para reducir el tiempo hasta la alimentacion enteral completa.
EP4032536A1 (en) 2021-01-26 2022-07-27 Probisearch, S.L.U. Probiotic composition for infants and its uses

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4895838A (en) 1988-03-09 1990-01-23 Trustees Of Boston University Method for provoking angiogenesis by administration of angiogenically active oligosaccharides
WO1991016449A1 (en) 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
US5545553A (en) 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
US6515016B2 (en) * 1996-12-02 2003-02-04 Angiotech Pharmaceuticals, Inc. Composition and methods of paclitaxel for treating psoriasis
US6132710A (en) * 1997-03-17 2000-10-17 Probiotix, Inc. Preventing/treating neonatal NEC by administering lactobacillus salivarius and lactobacillus plantarum or a combination thereof
EP1121143A2 (en) * 1998-03-27 2001-08-08 Dorothea J. Eicher Vegf and vegf-c as infant formula supplements
ES2416287T3 (es) * 2003-06-23 2013-07-31 Nestec S.A. Empleo de una fórmula nutritiva para la función óptima de la barrera intestinal
PT1675481E (pt) 2003-10-24 2009-01-02 Nutricia Nv Composição sinbiótica para bebés
US8252769B2 (en) 2004-06-22 2012-08-28 N. V. Nutricia Intestinal barrier integrity
JP2009523173A (ja) * 2006-01-09 2009-06-18 チルドレンズ ホスピタル メディカル センター 様々な病気の治療用のアディポネクチン
PL1988786T3 (pl) 2006-02-10 2010-10-29 Nestec Sa Mieszanka oligosacharydowa
PL1986669T3 (pl) * 2006-02-15 2012-09-28 Nestec Sa Zastosowanie Bifidobacterium longum do zapobiegania i leczenia zapalenia
BRPI0708689A2 (pt) * 2006-03-07 2011-06-07 Nestec Sa mistura simbiótica
AU2007227838B2 (en) * 2006-03-23 2012-10-25 N.V. Nutricia Preterm formula
EP2060257A1 (en) * 2007-11-08 2009-05-20 Nestec S.A. Prevention and treatment of secondary infections following viral infection
EP2072052A1 (en) * 2007-12-17 2009-06-24 Nestec S.A. Prevention of opportunistic infections in immune-compromised subjects
EP2143341A1 (en) * 2008-07-08 2010-01-13 Nestec S.A. Nutritional Composition Containing Oligosaccharide Mixture
CA2767960A1 (en) * 2009-07-31 2011-02-03 Nestec S.A. Nutritional composition for breast-fed infants or pets with probiotics and selected nutrients
EP2308498A1 (en) * 2009-09-30 2011-04-13 Nestec S.A. Administration of Bifidobacterium breve during infancy to prevent inflammation later in life
EP2455387A1 (en) 2010-11-23 2012-05-23 Nestec S.A. Oligosaccharide mixture and food product comprising this mixture, especially infant formula

Also Published As

Publication number Publication date
RU2624233C2 (ru) 2017-07-03
EP2768311B1 (en) 2018-02-21
EP2768311A1 (en) 2014-08-27
US20140286908A1 (en) 2014-09-25
CL2014000791A1 (es) 2014-08-22
WO2013057062A1 (en) 2013-04-25
ES2666491T3 (es) 2018-05-04
AU2012324985B2 (en) 2016-01-07
CN103889239A (zh) 2014-06-25
MX2014004719A (es) 2015-02-05
RU2014119904A (ru) 2015-11-27
AU2012324985A1 (en) 2014-03-20

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/7004 (2006.01), A23L 33/115 (2016.01), A23

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