BR112014004297A2 - compostos para uso em reforço da coagulação - Google Patents
compostos para uso em reforço da coagulaçãoInfo
- Publication number
- BR112014004297A2 BR112014004297A2 BR112014004297A BR112014004297A BR112014004297A2 BR 112014004297 A2 BR112014004297 A2 BR 112014004297A2 BR 112014004297 A BR112014004297 A BR 112014004297A BR 112014004297 A BR112014004297 A BR 112014004297A BR 112014004297 A2 BR112014004297 A2 BR 112014004297A2
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- coagulation enhancement
- coagulation
- enhancement
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Neurosurgery (AREA)
- Plant Pathology (AREA)
- Diabetes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161527140P | 2011-08-25 | 2011-08-25 | |
US61/527,140 | 2011-08-25 | ||
PCT/NL2012/050581 WO2013028070A2 (en) | 2011-08-25 | 2012-08-24 | Compounds for use in boosting coagulation |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014004297A2 true BR112014004297A2 (pt) | 2017-03-28 |
BR112014004297B1 BR112014004297B1 (pt) | 2021-12-14 |
Family
ID=46845975
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014004297-7A BR112014004297B1 (pt) | 2011-08-25 | 2012-08-24 | Uso de um inibidor de antitrombina iii no tratamento ou prevenção de sangramento |
Country Status (14)
Country | Link |
---|---|
US (1) | US20140356377A1 (pt) |
EP (1) | EP2747776B1 (pt) |
JP (2) | JP6198277B2 (pt) |
CN (1) | CN103930129A (pt) |
AU (1) | AU2012299524B2 (pt) |
BR (1) | BR112014004297B1 (pt) |
CA (1) | CA2846494C (pt) |
CY (1) | CY1120688T1 (pt) |
DK (1) | DK2747776T3 (pt) |
ES (1) | ES2689776T3 (pt) |
HU (1) | HUE039590T2 (pt) |
PL (1) | PL2747776T3 (pt) |
PT (1) | PT2747776T (pt) |
WO (1) | WO2013028070A2 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UY35457A (es) | 2013-03-14 | 2014-10-31 | Bayer Healthcare Llc | ANTICUERPOS MONOCLONALES CONTRA ANTITROMBINA ß |
EP3904519A1 (en) | 2014-10-30 | 2021-11-03 | Genzyme Corporation | Polynucleotide agents targeting serpinc1 (at3) and methods of use thereof |
IL308717A (en) | 2015-12-07 | 2024-01-01 | Genzyme Corp | Methods and preparations for the treatment of diseases related to SERPINC1 |
EP3430059A1 (en) * | 2016-03-18 | 2019-01-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anti-antithrombin single-domain antibodies and polypeptides comprising thereof |
GB201709970D0 (en) * | 2017-06-22 | 2017-08-09 | Kymab Ltd | Bispecific antigen-binding molecules |
PL3723858T3 (pl) | 2018-12-21 | 2022-03-07 | Kymab Limited | Przeciwciało dwuswoiste fixaxfx o wspólnym łańcuchu lekkim |
JP6883899B1 (ja) * | 2020-12-07 | 2021-06-09 | 株式会社血栓トランスレーショナルリサーチラボ | 血液凝固検査試薬、および血液凝固検査方法 |
PL440675A1 (pl) * | 2022-03-17 | 2023-09-18 | Politechnika Wrocławska | Związki do równoległego wykrywania i hamowania proteaz szlaku krzepnięcia - APC, trombiny, czynnika Xa i czynnika XIa w ludzkim osoczu |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US748913A (en) * | 1904-01-05 | Fo model | ||
JP2010533684A (ja) * | 2007-07-20 | 2010-10-28 | ユニベルシテ パリ サッド 11 | 血液凝固異常の治療又は予防のための変異アンチトロンビンの使用 |
DE102011081871A1 (de) * | 2011-08-31 | 2013-02-28 | Henkel Ag & Co. Kgaa | Oxazolidine zur Fehlgeruchsbekämpfung |
-
2012
- 2012-02-24 US US14/240,903 patent/US20140356377A1/en not_active Abandoned
- 2012-08-24 WO PCT/NL2012/050581 patent/WO2013028070A2/en active Application Filing
- 2012-08-24 HU HUE12758914A patent/HUE039590T2/hu unknown
- 2012-08-24 JP JP2014527112A patent/JP6198277B2/ja active Active
- 2012-08-24 BR BR112014004297-7A patent/BR112014004297B1/pt active IP Right Grant
- 2012-08-24 ES ES12758914.1T patent/ES2689776T3/es active Active
- 2012-08-24 CA CA2846494A patent/CA2846494C/en active Active
- 2012-08-24 PT PT12758914T patent/PT2747776T/pt unknown
- 2012-08-24 PL PL12758914T patent/PL2747776T3/pl unknown
- 2012-08-24 EP EP12758914.1A patent/EP2747776B1/en active Active
- 2012-08-24 DK DK12758914.1T patent/DK2747776T3/en active
- 2012-08-24 AU AU2012299524A patent/AU2012299524B2/en not_active Ceased
- 2012-08-24 CN CN201280052327.2A patent/CN103930129A/zh active Pending
-
2017
- 2017-04-20 JP JP2017083956A patent/JP2017186340A/ja active Pending
-
2018
- 2018-09-19 CY CY181100967T patent/CY1120688T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
PL2747776T3 (pl) | 2019-03-29 |
PT2747776T (pt) | 2018-10-31 |
CA2846494A1 (en) | 2013-02-28 |
BR112014004297B1 (pt) | 2021-12-14 |
EP2747776A2 (en) | 2014-07-02 |
AU2012299524A1 (en) | 2014-03-13 |
WO2013028070A2 (en) | 2013-02-28 |
CY1120688T1 (el) | 2019-12-11 |
JP2014529606A (ja) | 2014-11-13 |
CN103930129A (zh) | 2014-07-16 |
JP2017186340A (ja) | 2017-10-12 |
DK2747776T3 (en) | 2018-09-17 |
US20140356377A1 (en) | 2014-12-04 |
AU2012299524B2 (en) | 2017-03-23 |
CA2846494C (en) | 2020-10-20 |
JP6198277B2 (ja) | 2017-09-20 |
ES2689776T3 (es) | 2018-11-15 |
EP2747776B1 (en) | 2018-07-11 |
WO2013028070A3 (en) | 2013-04-18 |
HUE039590T2 (hu) | 2019-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/08/2012, OBSERVADAS AS CONDICOES LEGAIS. |