BR112014002745A2 - produção de isoprenoides sob condições de ph neutro - Google Patents
produção de isoprenoides sob condições de ph neutroInfo
- Publication number
- BR112014002745A2 BR112014002745A2 BR112014002745A BR112014002745A BR112014002745A2 BR 112014002745 A2 BR112014002745 A2 BR 112014002745A2 BR 112014002745 A BR112014002745 A BR 112014002745A BR 112014002745 A BR112014002745 A BR 112014002745A BR 112014002745 A2 BR112014002745 A2 BR 112014002745A2
- Authority
- BR
- Brazil
- Prior art keywords
- saccharification
- fermentation
- conditions
- isoprenoids
- under neutral
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/0101—(2E,6E)-Farnesyl diphosphate synthase (2.5.1.10), i.e. geranyltranstransferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01003—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
abstract: en)embodiments of the present disclosure relate to a process for producing isoprenoid precursor molecules and/or isoprenoids from a starch substrate by saccharification and/or fermentation. the saccharification is effectively catalyzed by a glucoamylase at a ph in the range of 5.0 to 8.0. at a ph of 6.0 or above, the glucoamylase possesses at least 50% activity relative to its maximum activity. the saccharification and fermentation may be performed as a simultaneous saccharification and fermentation (ssf) process ------------------------------------------------------------------------------ tradução das reivindicações resumo patente de invenção: "produção de isoprenoides sob condições de ph neutro". modalidades da presente descrição referem-se a um processo para produzir moléculas precursoras de isoprenoide e/ou isoprenoides a partir de um substrato de amido por sacarificação e/ou fermentação. a sacarifi-cação é efetivamente catalisada por uma glicoamilase em um ph na faixa de 5,0 a 8,0. em um ph de 6,0 ou acima, a glicoamilase possui pelo menos 50% de atividade em relação a sua atividade máxima. os processos de sa-carificação e fermentação podem ser executados como um processo si-multâneo de sacarificação e fermentação (ssf).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161515830P | 2011-08-05 | 2011-08-05 | |
PCT/US2012/049646 WO2013022799A1 (en) | 2011-08-05 | 2012-08-03 | PRODUCTION OF ISOPRENOIDS UNDER NEUTRAL pH CONDITIONS |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014002745A2 true BR112014002745A2 (pt) | 2017-06-13 |
BR112014002745A8 BR112014002745A8 (pt) | 2017-06-20 |
Family
ID=46724632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014002745A BR112014002745A8 (pt) | 2011-08-05 | 2012-08-03 | produção de isoprenoides sob condições de ph neutro |
Country Status (5)
Country | Link |
---|---|
US (1) | US8951764B2 (pt) |
EP (1) | EP2739742A1 (pt) |
BR (1) | BR112014002745A8 (pt) |
HK (1) | HK1198837A1 (pt) |
WO (1) | WO2013022799A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2807558A1 (en) * | 2010-08-06 | 2012-02-09 | Danisco Us Inc. | Production of isoprene under neutral ph conditions |
EP2561083B1 (en) * | 2010-08-06 | 2017-01-11 | Danisco US Inc. | Use of Humicola grisea glucoamylase in an SSF process at neutral pH |
EP3063263A1 (en) * | 2013-10-28 | 2016-09-07 | Danisco US Inc. | Large scale genetically engineered active dry yeast |
KR20200095534A (ko) | 2017-12-07 | 2020-08-10 | 지머젠 인코포레이티드 | 발효에 의한 (6e)-8-히드록시제라니올의 제조를 위해 조작된 생합성 경로 |
JP2021506316A (ja) | 2017-12-21 | 2021-02-22 | ザイマージェン インコーポレイテッド | ネペタラクトールオキシドレダクターゼ、ネペタラクトールシンターゼ、及びネペタラクトンを産生する能力がある微生物 |
WO2020071538A1 (en) | 2018-10-05 | 2020-04-09 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
CN110656056B (zh) * | 2019-10-31 | 2021-07-27 | 江南大学 | 一种高浓度蒎烯耐受性产蒎烯工程菌的构建方法 |
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EP2857518A3 (en) * | 2009-12-23 | 2015-04-22 | Danisco US Inc. | Compositions and methods of PGL for the increased production of isoprene |
CA2807558A1 (en) | 2010-08-06 | 2012-02-09 | Danisco Us Inc. | Production of isoprene under neutral ph conditions |
BR112014010750B1 (pt) * | 2011-11-09 | 2021-09-21 | Amyris, Inc | Produção de isoprenoides derivados de acetil-coenzima a |
-
2012
- 2012-08-03 BR BR112014002745A patent/BR112014002745A8/pt not_active IP Right Cessation
- 2012-08-03 US US13/566,923 patent/US8951764B2/en not_active Expired - Fee Related
- 2012-08-03 WO PCT/US2012/049646 patent/WO2013022799A1/en active Application Filing
- 2012-08-03 EP EP12750654.1A patent/EP2739742A1/en not_active Withdrawn
-
2014
- 2014-12-08 HK HK14112303.1A patent/HK1198837A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US8951764B2 (en) | 2015-02-10 |
WO2013022799A1 (en) | 2013-02-14 |
EP2739742A1 (en) | 2014-06-11 |
HK1198837A1 (en) | 2015-06-12 |
BR112014002745A8 (pt) | 2017-06-20 |
US20130203140A1 (en) | 2013-08-08 |
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Legal Events
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B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] | ||
B350 | Update of information on the portal [chapter 15.35 patent gazette] |