BR112013026114A2 - composições nutricionais que incluem ácidos graxos de cadeia ramificada e processos de utilização das mesmas - Google Patents
composições nutricionais que incluem ácidos graxos de cadeia ramificada e processos de utilização das mesmasInfo
- Publication number
- BR112013026114A2 BR112013026114A2 BR112013026114A BR112013026114A BR112013026114A2 BR 112013026114 A2 BR112013026114 A2 BR 112013026114A2 BR 112013026114 A BR112013026114 A BR 112013026114A BR 112013026114 A BR112013026114 A BR 112013026114A BR 112013026114 A2 BR112013026114 A2 BR 112013026114A2
- Authority
- BR
- Brazil
- Prior art keywords
- nutritional compositions
- branched chain
- fatty acids
- chain fatty
- processes
- Prior art date
Links
- 235000016709 nutrition Nutrition 0.000 title abstract 5
- 239000000203 mixture Substances 0.000 title abstract 4
- 235000014113 dietary fatty acids Nutrition 0.000 title abstract 3
- 229930195729 fatty acid Natural products 0.000 title abstract 3
- 239000000194 fatty acid Substances 0.000 title abstract 3
- 150000004665 fatty acids Chemical class 0.000 title abstract 3
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000006041 probiotic Substances 0.000 abstract 1
- 235000018291 probiotics Nutrition 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/13—Nucleic acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A—HUMAN NECESSITIES
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/064—Saccharomycetales, e.g. baker's yeast
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P1/12—Antidiarrhoeals
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Botany (AREA)
- Immunology (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Pediatric Medicine (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Hematology (AREA)
Abstract
resumo patente de invenção: "composições nutricionais que incluem ácidos graxos de cadeia ramificada e processos de utilização das mesmas". a presente invenção refere-se a composições nutricionais para melhorar, tratar e/ou evitar várias condições médicas e métodos de uso das mesmas. as condições médicas podem incluir alergias, doenças autoimunes, entre outras. as composições nutricionais incluem ácidos graxos de cadeia ramificada e podem incluir outros ingredientes funcionais tais como, porém não limitados a probióticos, nucleotídeos e aminoácidos. os métodos de administração de tais produtos nutricionais a indivíduos que necessitem também são fornecidos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161474452P | 2011-04-12 | 2011-04-12 | |
PCT/EP2012/056664 WO2012140133A1 (en) | 2011-04-12 | 2012-04-12 | Nutritional compositions including branched chain fatty acids and methods of using same |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013026114A2 true BR112013026114A2 (pt) | 2016-12-27 |
Family
ID=45976923
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013026082A BR112013026082A2 (pt) | 2011-04-12 | 2012-04-12 | composições nutricionais incluindo ácidos graxos de cadeia ramificada para melhorar função de barreira intestinal |
BR112013026114A BR112013026114A2 (pt) | 2011-04-12 | 2012-04-12 | composições nutricionais que incluem ácidos graxos de cadeia ramificada e processos de utilização das mesmas |
BR112013026032A BR112013026032A2 (pt) | 2011-04-12 | 2012-04-12 | composições nutricionais incluindo ácidos graxos de cadeia ramificada para cicatrização de ferida |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013026082A BR112013026082A2 (pt) | 2011-04-12 | 2012-04-12 | composições nutricionais incluindo ácidos graxos de cadeia ramificada para melhorar função de barreira intestinal |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013026032A BR112013026032A2 (pt) | 2011-04-12 | 2012-04-12 | composições nutricionais incluindo ácidos graxos de cadeia ramificada para cicatrização de ferida |
Country Status (11)
Country | Link |
---|---|
US (3) | US20140037603A1 (pt) |
EP (3) | EP2696866A1 (pt) |
JP (3) | JP2014514304A (pt) |
CN (3) | CN103458890A (pt) |
AU (3) | AU2012241814A1 (pt) |
BR (3) | BR112013026082A2 (pt) |
CA (3) | CA2831679A1 (pt) |
MX (3) | MX2013011835A (pt) |
SG (3) | SG193928A1 (pt) |
WO (3) | WO2012140118A1 (pt) |
ZA (2) | ZA201308478B (pt) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11179427B2 (en) | 2013-01-21 | 2021-11-23 | Eth Zurich | Baby food composition comprising viable propionic acid-producing bacteria |
ITMI20130476A1 (it) | 2013-03-28 | 2014-09-29 | Novintethical Pharma Sagl | Composizioni per il trattamento di disturbi gastro-intestinali a base di complessi di tannini con proteine |
GB2516266A (en) * | 2013-07-17 | 2015-01-21 | Ziqian Jia | A composition |
CN103798596B (zh) * | 2014-02-28 | 2015-04-22 | 青岛市中心医院 | 一种供心脑血管疾病患者食用的全营养配方食品 |
WO2015154259A1 (en) * | 2014-04-09 | 2015-10-15 | Nestle (China) Ltd. | Gender specific synthetic nutritional compositions and nutritional systems comprising them |
WO2015167002A1 (ja) * | 2014-04-30 | 2015-11-05 | 味の素株式会社 | 消化管障害を改善する組成物 |
GB201417016D0 (en) * | 2014-09-26 | 2014-11-12 | Micromass Ltd | Accurate mobility chromatograms |
EP3616689A1 (en) * | 2014-11-24 | 2020-03-04 | Entrinsic Health Solutions, Inc. | Amino acid compositions for the treatment of symptoms of disease |
CN104544454A (zh) * | 2014-12-19 | 2015-04-29 | 渤海大学 | 一种海参肽营养粉及其制备方法 |
WO2016116580A1 (en) * | 2015-01-23 | 2016-07-28 | Nestec S.A. | Nutritional composition useful in the treatment of ibd patients |
US20160324904A1 (en) * | 2015-05-05 | 2016-11-10 | Ryozo Saito | Supplement for improving immunotolerance, intestinal environment and intestinal tract barrier |
US20180071237A1 (en) * | 2015-05-05 | 2018-03-15 | Ryozo Saito | Treatment method for improving intestinal enviornment and intestinal tract barrier |
US11234949B2 (en) * | 2015-05-14 | 2022-02-01 | Professional Dietetics S.P.A. | Compositions comprising amino acids for use in the treatment of mucositides in neoplasia patients undergoing radiation therapy and/or chemotherapy |
WO2016183535A1 (en) | 2015-05-14 | 2016-11-17 | University Of Puerto Rico | Methods for restoring microbiota of newborns |
JP6964960B2 (ja) * | 2015-11-13 | 2021-11-10 | ニュートリー株式会社 | 術後の創傷部及び/又は吻合部の回復を促進するための栄養組成物 |
CN108348483A (zh) * | 2015-12-04 | 2018-07-31 | 雀巢产品技术援助有限公司 | 用于治疗或预防与组织中的超过正常数量的粒细胞相关联的疾病的可可多酚和可溶膳食纤维 |
WO2017117142A1 (en) | 2015-12-28 | 2017-07-06 | New York University | Device and method of restoring microbiota of newborns |
CN105901703B (zh) * | 2016-04-19 | 2020-03-10 | 上海海洋大学 | 一种用于烧伤患者的海洋生物型肠内营养制剂 |
CN106036655A (zh) * | 2016-06-21 | 2016-10-26 | 宋庆利 | 一种主食制品及其用途以及含其的含乳饮料的制备方法 |
CN106213522A (zh) * | 2016-08-05 | 2016-12-14 | 郑家福 | 营养保健品 |
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CN103458888A (zh) | 2013-12-18 |
US20140037603A1 (en) | 2014-02-06 |
CN103458889A (zh) | 2013-12-18 |
CA2830970A1 (en) | 2012-10-18 |
MX2013011834A (es) | 2014-02-11 |
AU2012241814A1 (en) | 2013-10-03 |
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CN103458890A (zh) | 2013-12-18 |
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EP2696868A1 (en) | 2014-02-19 |
AU2012241895A1 (en) | 2013-10-03 |
US20140037602A1 (en) | 2014-02-06 |
AU2012241815A1 (en) | 2013-09-26 |
JP2014514304A (ja) | 2014-06-19 |
EP2696866A1 (en) | 2014-02-19 |
JP2014510775A (ja) | 2014-05-01 |
ZA201308478B (en) | 2015-08-26 |
SG193927A1 (en) | 2013-11-29 |
CA2831341A1 (en) | 2012-10-18 |
SG193926A1 (en) | 2013-11-29 |
SG193928A1 (en) | 2013-11-29 |
EP2696867A1 (en) | 2014-02-19 |
US20140037601A1 (en) | 2014-02-06 |
ZA201308469B (en) | 2015-08-26 |
BR112013026082A2 (pt) | 2019-09-24 |
MX2013011836A (es) | 2014-02-11 |
BR112013026032A2 (pt) | 2016-12-20 |
WO2012140133A1 (en) | 2012-10-18 |
WO2012140118A1 (en) | 2012-10-18 |
CA2831679A1 (en) | 2012-10-18 |
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