BR112013024784A2 - análogos de peptídeos de ação prolongada - Google Patents

análogos de peptídeos de ação prolongada

Info

Publication number
BR112013024784A2
BR112013024784A2 BR112013024784A BR112013024784A BR112013024784A2 BR 112013024784 A2 BR112013024784 A2 BR 112013024784A2 BR 112013024784 A BR112013024784 A BR 112013024784A BR 112013024784 A BR112013024784 A BR 112013024784A BR 112013024784 A2 BR112013024784 A2 BR 112013024784A2
Authority
BR
Brazil
Prior art keywords
long acting
peptide analogs
acting peptide
analogs
long
Prior art date
Application number
BR112013024784A
Other languages
English (en)
Inventor
Lin Chang Chia
Yu Hsu Sheau
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of BR112013024784A2 publication Critical patent/BR112013024784A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/585—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR112013024784A 2011-04-07 2012-04-05 análogos de peptídeos de ação prolongada BR112013024784A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161473054P 2011-04-07 2011-04-07
US201161474177P 2011-04-11 2011-04-11
US201161474182P 2011-04-11 2011-04-11
PCT/US2012/032333 WO2012138867A2 (en) 2011-04-07 2012-04-05 Long-acting peptide analogs

Publications (1)

Publication Number Publication Date
BR112013024784A2 true BR112013024784A2 (pt) 2018-09-25

Family

ID=46969817

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013024784A BR112013024784A2 (pt) 2011-04-07 2012-04-05 análogos de peptídeos de ação prolongada

Country Status (11)

Country Link
US (3) US9694051B2 (pt)
EP (1) EP2696884B1 (pt)
JP (2) JP6143740B2 (pt)
KR (1) KR20140027232A (pt)
CN (1) CN103458916B (pt)
AU (2) AU2012240144B2 (pt)
BR (1) BR112013024784A2 (pt)
CA (1) CA2830372A1 (pt)
RU (1) RU2664859C2 (pt)
TW (2) TWI561242B (pt)
WO (1) WO2012138867A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012138867A2 (en) 2011-04-07 2012-10-11 The Board Of Trustees Of The Leland Stanford Junior University Long-acting peptide analogs
EP3127914A4 (en) * 2014-03-20 2017-11-22 University of Miyazaki Long-acting adrenomedullin derivatives
TN2017000109A1 (en) * 2014-09-26 2018-07-04 Bayer Pharma AG Stabilized adrenomedullin derivatives and use thereof
WO2016183479A1 (en) * 2015-05-13 2016-11-17 The Board Of Regents Of The University Of Oklahoma Variants of adrenomedullin and calcitonin gene-related peptide and methods of use
RU2738416C2 (ru) * 2015-09-18 2020-12-14 Юниверсити Оф Миязаки Длительно действующее производное адреномедуллина
US11034745B2 (en) 2016-01-04 2021-06-15 Adepthera Llc Superagonist polypeptide analogs of adrenomedullin and intermedin peptide hormones
EP3416676B1 (en) * 2016-02-09 2021-12-08 Adepthera LLC Dosing and use of long-acting clr/ramp agonists
JP6781974B2 (ja) * 2016-03-31 2020-11-11 国立大学法人 宮崎大学 アドレノメデュリン凍結乾燥製剤の製造方法
WO2018181638A1 (ja) 2017-03-29 2018-10-04 国立大学法人宮崎大学 長時間作用型アドレノメデュリン誘導体
WO2019005623A1 (en) 2017-06-30 2019-01-03 Adepthera Llc PEPTIDE ANALOGS
CA3075252C (en) * 2017-09-27 2020-12-08 Novel Pharma Inc. Long-acting palmitic acid-conjugated gnrh derivatives and pharmaceutical compositions containing same
US20190287217A1 (en) * 2018-03-13 2019-09-19 Microsoft Technology Licensing, Llc Machine learning system for reduced network bandwidth transmission of content
CN108484727B (zh) * 2018-03-23 2020-08-28 中国药科大学 一种寡肽及其衍生物和应用
CN108409834B (zh) * 2018-03-23 2020-08-28 中国药科大学 一种寡肽及其衍生物和应用
EP3785734B1 (en) 2019-03-26 2023-04-12 Novel Pharma Inc. Long-acting fatty acid-binding gnrh derivative and pharmaceutical composition comprising same
US20220387608A1 (en) 2019-06-18 2022-12-08 Bayer Aktiengesellschaft Adrenomedullin-analogues for long-term stabilization and their use

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US4753788A (en) 1985-01-31 1988-06-28 Vestar Research Inc. Method for preparing small vesicles using microemulsification
US4935171A (en) 1989-01-27 1990-06-19 Vestar, Inc. Method for vesicle formation
US6132764A (en) 1994-08-05 2000-10-17 Targesome, Inc. Targeted polymerized liposome diagnostic and treatment agents
US5512294A (en) 1994-08-05 1996-04-30 Li; King C. Targeted polymerized liposome contrast agents
US5869602A (en) * 1995-03-17 1999-02-09 Novo Nordisk A/S Peptide derivatives
WO1996029432A1 (en) * 1995-03-22 1996-09-26 Trustees Of Boston University Methods for the detection of paracoccidioides
US6440421B1 (en) * 1996-04-18 2002-08-27 Auchkland Uniservices Limited Treatment of bone disorders with adrenomedullin or adrenomedullin agonists
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US6268474B1 (en) 1998-04-30 2001-07-31 Creighton University Peptide antagonists of CGRP-receptor superfamily and methods of use
US20090175821A1 (en) * 1999-05-17 2009-07-09 Bridon Dominique P Modified therapeutic peptides with extended half-lives in vivo
CA2425508A1 (en) 2000-10-11 2002-04-18 John S. Pease Targeted therapeutic agents
US20080026995A1 (en) * 2003-07-25 2008-01-31 Ac Immune Sa Therapeutic vaccine targeted against p-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
AU2005320351B2 (en) 2004-02-11 2010-06-03 Amylin Pharmaceuticals, Llc Amylin family peptides and methods for making and using them
ZA200700359B (en) 2004-07-21 2008-12-31 Ambrx Inc Biosynthetic polypeptides utilizing non-naturally encoded amino acids
CA2569381A1 (en) * 2004-07-21 2006-08-31 Ambrx, Inc. Biosynthetic polypeptides utilizing non-naturally encoded amino acids
BRPI0516574A (pt) 2004-10-08 2008-09-16 Amylin Pharmaceuticals Inc análogos do polipeptìdeo-6 da famìlia amilina (afp-6) e métodos para preparar e usar os mesmos
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
KR20070115947A (ko) 2005-02-11 2007-12-06 아밀린 파마슈티칼스, 인크. 선택가능한 특성들을 가지는 ｇｉｐ 유사체 및 하이브리드폴리펩타이드
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US8623606B2 (en) * 2006-08-22 2014-01-07 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Screening method for GPCR ligands
DK2615108T3 (en) * 2006-09-08 2017-01-30 Ambrx Inc Modified human plasma polypeptide or fc scaffolds and their applications
US7960336B2 (en) 2007-08-03 2011-06-14 Pharmain Corporation Composition for long-acting peptide analogs
WO2012138867A2 (en) 2011-04-07 2012-10-11 The Board Of Trustees Of The Leland Stanford Junior University Long-acting peptide analogs

Also Published As

Publication number Publication date
WO2012138867A3 (en) 2012-12-13
US20190183978A1 (en) 2019-06-20
TWI635868B (zh) 2018-09-21
US20140155329A1 (en) 2014-06-05
US11666633B2 (en) 2023-06-06
EP2696884A4 (en) 2014-12-24
US20170014485A1 (en) 2017-01-19
JP6143740B2 (ja) 2017-06-07
EP2696884A2 (en) 2014-02-19
CA2830372A1 (en) 2012-10-11
TW201717996A (zh) 2017-06-01
AU2012240144B2 (en) 2017-05-25
AU2012240144A1 (en) 2013-10-03
CN103458916B (zh) 2016-08-10
EP2696884B1 (en) 2019-04-03
RU2664859C2 (ru) 2018-08-23
US10058592B2 (en) 2018-08-28
JP6522020B2 (ja) 2019-05-29
US9694051B2 (en) 2017-07-04
KR20140027232A (ko) 2014-03-06
JP2014511862A (ja) 2014-05-19
CN103458916A (zh) 2013-12-18
TW201302218A (zh) 2013-01-16
TWI561242B (en) 2016-12-11
WO2012138867A2 (en) 2012-10-11
JP2017082000A (ja) 2017-05-18
AU2017213562A1 (en) 2017-08-31
RU2013149397A (ru) 2015-05-20

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25G Requested change of headquarter approved

Owner name: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements