BR112013021882A2 - síntese de compostos orgânicos - Google Patents
síntese de compostos orgânicosInfo
- Publication number
- BR112013021882A2 BR112013021882A2 BR112013021882A BR112013021882A BR112013021882A2 BR 112013021882 A2 BR112013021882 A2 BR 112013021882A2 BR 112013021882 A BR112013021882 A BR 112013021882A BR 112013021882 A BR112013021882 A BR 112013021882A BR 112013021882 A2 BR112013021882 A2 BR 112013021882A2
- Authority
- BR
- Brazil
- Prior art keywords
- synthesis
- organic compounds
- useful
- processes
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/26—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161448774P | 2011-03-03 | 2011-03-03 | |
PCT/EP2012/053559 WO2012117071A1 (en) | 2011-03-03 | 2012-03-01 | Synthesis of 2-carboxamide cycloamino urea derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013021882A2 true BR112013021882A2 (pt) | 2016-07-19 |
Family
ID=45787206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013021882A BR112013021882A2 (pt) | 2011-03-03 | 2012-03-01 | síntese de compostos orgânicos |
Country Status (32)
Country | Link |
---|---|
US (3) | US9650373B2 (pt) |
EP (1) | EP2681192B1 (pt) |
JP (1) | JP6022485B2 (pt) |
KR (1) | KR101851421B1 (pt) |
CN (2) | CN106083840B (pt) |
AR (2) | AR088714A1 (pt) |
AU (1) | AU2012222346B2 (pt) |
BR (1) | BR112013021882A2 (pt) |
CA (1) | CA2828509C (pt) |
CL (1) | CL2013002521A1 (pt) |
CO (1) | CO6751286A2 (pt) |
DK (1) | DK2681192T3 (pt) |
EA (4) | EA201691331A1 (pt) |
EC (1) | ECSP13012914A (pt) |
ES (1) | ES2663717T3 (pt) |
GT (1) | GT201300211A (pt) |
HU (1) | HUE036319T2 (pt) |
IL (1) | IL228023A (pt) |
MA (1) | MA34982B1 (pt) |
MX (2) | MX347348B (pt) |
MY (1) | MY163214A (pt) |
NO (1) | NO2681192T3 (pt) |
PE (1) | PE20140917A1 (pt) |
PL (1) | PL2681192T3 (pt) |
PT (1) | PT2681192T (pt) |
SG (1) | SG192793A1 (pt) |
SI (1) | SI2681192T1 (pt) |
TN (1) | TN2013000354A1 (pt) |
TW (2) | TWI597279B (pt) |
UA (1) | UA112539C2 (pt) |
WO (1) | WO2012117071A1 (pt) |
ZA (1) | ZA201306174B (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA112539C2 (uk) * | 2011-03-03 | 2016-09-26 | Новартіс Аг | Спосіб одержання похідних 2-карбоксамідциклоаміносечовини |
CN111704543A (zh) * | 2014-11-14 | 2020-09-25 | 燿石治疗公司 | 用于制备α,ω-二羧酸封端的二烷醚的方法和中间体 |
JP7014737B2 (ja) | 2017-01-20 | 2022-02-01 | 株式会社ペーターズ | スケートボード用ハンドル及びハンドル付きスケートボード |
CN112961090A (zh) * | 2019-12-13 | 2021-06-15 | 武汉九州钰民医药科技有限公司 | 合成Alpelisib的关键中间体及其制备方法 |
CN110964005A (zh) * | 2019-12-16 | 2020-04-07 | 武汉九州钰民医药科技有限公司 | 一种Alpelisib的制备工艺 |
CN111057051A (zh) * | 2019-12-16 | 2020-04-24 | 武汉九州钰民医药科技有限公司 | PI3K抑制剂Alpelisib的新合成方法 |
KR20220125753A (ko) | 2021-03-05 | 2022-09-14 | 배성륭 | 기능성 풍력 발전시스템 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3534056A (en) * | 1967-03-02 | 1970-10-13 | Pennwalt Corp | Fluoro-alkyl pyridines and their preparation |
UA60365C2 (uk) | 1998-06-04 | 2003-10-15 | Пфайзер Продактс Інк. | Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця |
WO2001017995A1 (en) | 1999-09-10 | 2001-03-15 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
TW200519106A (en) * | 2003-05-02 | 2005-06-16 | Novartis Ag | Organic compounds |
WO2007087427A2 (en) | 2006-01-25 | 2007-08-02 | Synta Pharmaceuticals Corp. | Thiazole and thiadiazole compounds for inflammation and immune-related uses |
TWI428091B (zh) | 2007-10-23 | 2014-03-01 | Du Pont | 殺真菌劑混合物 |
US8940771B2 (en) | 2007-12-20 | 2015-01-27 | Novartis Ag | Organic compounds |
US20100296486A1 (en) * | 2007-12-21 | 2010-11-25 | Carlo Sansone | Method, Apparatus and Computer Program for Handover From A First Access Point To A Second Access Point |
UA104147C2 (uk) | 2008-09-10 | 2014-01-10 | Новартис Аг | Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань |
UA112539C2 (uk) * | 2011-03-03 | 2016-09-26 | Новартіс Аг | Спосіб одержання похідних 2-карбоксамідциклоаміносечовини |
-
2012
- 2012-01-03 UA UAA201310018A patent/UA112539C2/uk unknown
- 2012-03-01 PL PL12706843T patent/PL2681192T3/pl unknown
- 2012-03-01 EA EA201691331A patent/EA201691331A1/ru unknown
- 2012-03-01 AU AU2012222346A patent/AU2012222346B2/en active Active
- 2012-03-01 BR BR112013021882A patent/BR112013021882A2/pt not_active Application Discontinuation
- 2012-03-01 MX MX2013010132A patent/MX347348B/es active IP Right Grant
- 2012-03-01 MA MA36278A patent/MA34982B1/fr unknown
- 2012-03-01 WO PCT/EP2012/053559 patent/WO2012117071A1/en active Application Filing
- 2012-03-01 KR KR1020137025764A patent/KR101851421B1/ko active IP Right Grant
- 2012-03-01 SI SI201231240T patent/SI2681192T1/en unknown
- 2012-03-01 SG SG2013062153A patent/SG192793A1/en unknown
- 2012-03-01 PT PT127068435T patent/PT2681192T/pt unknown
- 2012-03-01 CN CN201610412757.0A patent/CN106083840B/zh active Active
- 2012-03-01 NO NO12706843A patent/NO2681192T3/no unknown
- 2012-03-01 US US13/985,069 patent/US9650373B2/en active Active
- 2012-03-01 DK DK12706843.5T patent/DK2681192T3/en active
- 2012-03-01 MX MX2017005292A patent/MX351740B/es unknown
- 2012-03-01 EA EA201792068A patent/EA032802B1/ru not_active IP Right Cessation
- 2012-03-01 MY MYPI2013002966A patent/MY163214A/en unknown
- 2012-03-01 CN CN201280011348.XA patent/CN103402982B/zh active Active
- 2012-03-01 CA CA2828509A patent/CA2828509C/en active Active
- 2012-03-01 EA EA201892052A patent/EA201892052A1/ru unknown
- 2012-03-01 EA EA201391267A patent/EA025381B1/ru not_active IP Right Cessation
- 2012-03-01 PE PE2013002003A patent/PE20140917A1/es not_active Application Discontinuation
- 2012-03-01 EP EP12706843.5A patent/EP2681192B1/en active Active
- 2012-03-01 AR ARP120100665A patent/AR088714A1/es active IP Right Grant
- 2012-03-01 HU HUE12706843A patent/HUE036319T2/hu unknown
- 2012-03-01 JP JP2013555878A patent/JP6022485B2/ja active Active
- 2012-03-01 ES ES12706843.5T patent/ES2663717T3/es active Active
- 2012-03-02 TW TW101107070A patent/TWI597279B/zh not_active IP Right Cessation
- 2012-03-02 TW TW106106845A patent/TWI607994B/zh not_active IP Right Cessation
-
2013
- 2013-08-16 ZA ZA2013/06174A patent/ZA201306174B/en unknown
- 2013-08-19 IL IL228023A patent/IL228023A/en active IP Right Grant
- 2013-08-28 TN TNP2013000354A patent/TN2013000354A1/fr unknown
- 2013-08-28 GT GT201300211A patent/GT201300211A/es unknown
- 2013-08-30 CO CO13206319A patent/CO6751286A2/es unknown
- 2013-09-02 CL CL2013002521A patent/CL2013002521A1/es unknown
- 2013-10-02 EC ECSP13012914 patent/ECSP13012914A/es unknown
-
2017
- 2017-04-06 US US15/480,835 patent/US9776966B2/en active Active
- 2017-08-23 US US15/684,419 patent/US10059670B2/en active Active
-
2021
- 2021-09-23 AR ARP210102644A patent/AR123584A2/es unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B15K | Others concerning applications: alteration of classification |
Free format text: AS CLASSIFICACOES ANTERIORES ERAM: C07D 213/26 , C07D 417/04 , C07D 417/14 Ipc: C07D 213/26 (2006.01), C07D 417/04 (2006.01), C07D |
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B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] |
Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO EM FUNCAO DA REVOGACAO DO ART. 229-C DA LEI NO 9.279, DE 1996, POR FORCA DA LEI NO 14.195, DE 2021 |
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B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 10A ANUIDADE. |
|
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |