BR112013018522A2 - compostos e métodos para promover o crescimento capilar - Google Patents
compostos e métodos para promover o crescimento capilarInfo
- Publication number
- BR112013018522A2 BR112013018522A2 BR112013018522A BR112013018522A BR112013018522A2 BR 112013018522 A2 BR112013018522 A2 BR 112013018522A2 BR 112013018522 A BR112013018522 A BR 112013018522A BR 112013018522 A BR112013018522 A BR 112013018522A BR 112013018522 A2 BR112013018522 A2 BR 112013018522A2
- Authority
- BR
- Brazil
- Prior art keywords
- hair
- hair growth
- compounds
- methods
- agonist
- Prior art date
Links
- 230000003779 hair growth Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title abstract 2
- 210000004209 hair Anatomy 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 4
- 239000000556 agonist Substances 0.000 abstract 2
- 210000003491 skin Anatomy 0.000 abstract 2
- 230000004936 stimulating effect Effects 0.000 abstract 2
- -1 1-isopropyl ester Chemical class 0.000 abstract 1
- 241001311547 Patina Species 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 210000004709 eyebrow Anatomy 0.000 abstract 1
- 210000000720 eyelash Anatomy 0.000 abstract 1
- 210000003780 hair follicle Anatomy 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- WGJJROVFWIXTPA-OALUTQOASA-N prostanoic acid Chemical compound CCCCCCCC[C@H]1CCC[C@@H]1CCCCCCC(O)=O WGJJROVFWIXTPA-OALUTQOASA-N 0.000 abstract 1
- 210000004761 scalp Anatomy 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
compostos e métodos para promover o crescimento capilar a presente invenção fornece um método para estimulação do crescimento capilar em uma espécie mamífera ou para conversão de velo capilar ou cabelo intermediário em cabelo terminal ou para estimulação dos folículos capilares para o aumento do crescimento capilar e uma ou mais propriedades selecionadas do grupo que consiste de dar lustro, claridade, brilho, acetinado, luminosidade, reflexo ou pátina do cabelo associado com os folículos ou aumento de um ou mais de: comprimento, espessura, número e densidade de cílios ou sombrancelhas compreendendo a aplicação à pele de um paciente de uma composição compreendendo uma quantidade eficaz de um agonista de profármaco ep3 ou um agonista ep4 ou uma mistura deles. tais composições que são usadas no tratamento da pele ou do couro cabeludo de um ser humano ou não humano podem compreender uma quantidade eficaz de um ácido 3,7 ou 3 e 7 tia prostanóico. uma mistura de 3,7-dita pge1 e 3,7-ditapge1-isopropil éster é preferida para este tratamento.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161435126P | 2011-01-21 | 2011-01-21 | |
PCT/US2012/022133 WO2012100238A2 (en) | 2011-01-21 | 2012-01-21 | Compounds and methods for enhancing hair growth |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013018522A2 true BR112013018522A2 (pt) | 2016-10-18 |
Family
ID=45558824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013018522A BR112013018522A2 (pt) | 2011-01-21 | 2012-01-21 | compostos e métodos para promover o crescimento capilar |
Country Status (9)
Country | Link |
---|---|
US (1) | US8859616B2 (pt) |
EP (1) | EP2665476A2 (pt) |
JP (1) | JP2014512335A (pt) |
KR (1) | KR20140009310A (pt) |
CN (1) | CN103717216A (pt) |
BR (1) | BR112013018522A2 (pt) |
CA (1) | CA2824996A1 (pt) |
RU (1) | RU2013138264A (pt) |
WO (1) | WO2012100238A2 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016159916A1 (en) * | 2015-03-31 | 2016-10-06 | Ogi̇g Sağlik Ürünleri̇ Ve Hi̇zmetleri̇ Sanayi̇ Ti̇caret Li̇mi̇ted Şi̇rketi̇ | A foamy pharmaceutical formulation used in dermatological diseases |
IT201800002630A1 (it) * | 2018-02-13 | 2019-08-13 | Giuliani Spa | Composizione per la prevenzione e il trattamento dei disturbi della crescita dei capelli |
EP4357349A1 (en) | 2021-06-15 | 2024-04-24 | Hodogaya Chemical Co., Ltd. | Amine compound having azabenzoxazole ring structure, and organic electroluminescent element using same |
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BE755555A (fr) | 1969-09-02 | 1971-03-01 | Richardson Merrell Inc | Derives de quinoxaline |
JPS4969636A (pt) | 1972-11-07 | 1974-07-05 | ||
FR2239458A1 (en) | 1973-07-31 | 1975-02-28 | Aries Robert | Prostaglandin amides - with antilipolytic, gonadotrophic, luteolytic, hypotensive and other activities associated with prostaglandins |
US4128577A (en) | 1975-12-29 | 1978-12-05 | The Upjohn Company | 15-Methyl- and 16-phenoxy-PGF2 α, amides |
US4596812A (en) | 1976-05-24 | 1986-06-24 | The Upjohn Company | Methods and solutions for treating male pattern alopecia |
US4139619A (en) | 1976-05-24 | 1979-02-13 | The Upjohn Company | 6-Amino-4-(substituted amino)-1,2-dihydro-1-hydroxy-2-iminopyrimidine, topical compositions and process for hair growth |
US4311707A (en) | 1979-02-12 | 1982-01-19 | American Cyanamid Company | Process for topically producing cutaneous vasodilation for the treatment of vasospastic or ischemic conditions |
US4543353A (en) | 1981-11-27 | 1985-09-24 | Farmitalia Carlo Erba S.P.A. | Ester and amide derivatives of 13,14-didehydro prostaglandins |
US4599353A (en) | 1982-05-03 | 1986-07-08 | The Trustees Of Columbia University In The City Of New York | Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma |
NZ212914A (en) | 1984-07-31 | 1988-08-30 | Syntex Inc | Tetranorprostaglandin derivatives and pharmaceutical compositions |
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US20020146439A1 (en) * | 2000-03-31 | 2002-10-10 | Delong Mitchell Anthony | Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins |
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FR2812191B1 (fr) * | 2000-07-28 | 2003-10-17 | Oreal | Utilisation d'agonistes du recepteur des prostaglandines e2 (ep-3) pour attenuer, diminuer ou stopper la pousse des cheveux et des poils dans des preparations cosmetiques |
FR2812193B1 (fr) * | 2000-07-28 | 2003-10-24 | Oreal | Utilisation d'antagoniste des recepteurs des prostaglandines ep-2 et/ou ep-4 pour attenuer, diminuer ou stopper la pousse des cheveux et des poils dans des preparations cosmetiques |
FR2812190B1 (fr) | 2000-07-28 | 2003-01-31 | Oreal | Utilisation d'agonistes non prostanoiques des recepteurs des prostaglandines ep-2 et/ou ep-4 comme agent cosmetique permettant d'attenuer, de diminuer ou d'arreter la chute des cheveux et des poils |
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US7320967B2 (en) | 2002-04-23 | 2008-01-22 | L'oreal | Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair |
US20030199590A1 (en) | 2002-07-25 | 2003-10-23 | Cagle Gerald D | Prostaglandin analogues for promotion of hair growth |
CA2515440A1 (fr) * | 2003-02-12 | 2004-09-02 | L'oreal | Utilisation d'un inhibiteur de 15-hydroxy prostaglandine deshydrogenase pour favoriser la pigmentation de la peau ou des phaneres |
US20070078175A1 (en) | 2005-10-05 | 2007-04-05 | L'oreal | Administration of novel phenylfurylmethylthiazolidine-2,4-dione and phenylthienylmethylthiazolidine-2,4-dione compounds for stimulating or inducing the growth of keratinous fibers and/or slowing loss thereof |
US20090018204A1 (en) | 2007-07-13 | 2009-01-15 | Brinkenhoff Michael C | Composition and method for enhancing hair growth |
US20110002866A1 (en) * | 2007-10-31 | 2011-01-06 | Lubit Beverly W | Methods to prevent a hair-related side effect of treatment with a chemotherapeutic agent |
US20100074857A1 (en) * | 2008-09-23 | 2010-03-25 | Pamela Lipkin | Compositions and methods to treat epithelial-related conditions |
EP2288600A1 (en) * | 2008-04-24 | 2011-03-02 | Allergan, Inc. | Substituted arylcyclopentenes as prostaglandin ep2 agonists |
US20120129789A1 (en) | 2010-11-18 | 2012-05-24 | Steven Yoelin | Compositions and methods for hair growth |
KR20140020895A (ko) * | 2011-01-31 | 2014-02-19 | 알러간, 인코포레이티드 | 모발 성장 증진 방법 |
EP2675786B1 (en) * | 2011-02-14 | 2018-12-26 | Allergan, Inc. | Ester derivatives of bimatoprost compositions and methods |
-
2012
- 2012-01-20 US US13/354,479 patent/US8859616B2/en active Active
- 2012-01-21 BR BR112013018522A patent/BR112013018522A2/pt not_active IP Right Cessation
- 2012-01-21 RU RU2013138264/15A patent/RU2013138264A/ru unknown
- 2012-01-21 KR KR1020137021451A patent/KR20140009310A/ko not_active Application Discontinuation
- 2012-01-21 JP JP2013550653A patent/JP2014512335A/ja active Pending
- 2012-01-21 EP EP12701973.5A patent/EP2665476A2/en not_active Withdrawn
- 2012-01-21 CN CN201280014437.XA patent/CN103717216A/zh active Pending
- 2012-01-21 WO PCT/US2012/022133 patent/WO2012100238A2/en active Application Filing
- 2012-01-21 CA CA2824996A patent/CA2824996A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2665476A2 (en) | 2013-11-27 |
US20120190733A1 (en) | 2012-07-26 |
CA2824996A1 (en) | 2012-07-26 |
WO2012100238A3 (en) | 2014-07-03 |
KR20140009310A (ko) | 2014-01-22 |
WO2012100238A2 (en) | 2012-07-26 |
JP2014512335A (ja) | 2014-05-22 |
RU2013138264A (ru) | 2015-02-27 |
US8859616B2 (en) | 2014-10-14 |
CN103717216A (zh) | 2014-04-09 |
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