BR112013001508A2 - composição farmacêutica com características de solubilidade intensificadas - Google Patents

composição farmacêutica com características de solubilidade intensificadas

Info

Publication number
BR112013001508A2
BR112013001508A2 BR112013001508A BR112013001508A BR112013001508A2 BR 112013001508 A2 BR112013001508 A2 BR 112013001508A2 BR 112013001508 A BR112013001508 A BR 112013001508A BR 112013001508 A BR112013001508 A BR 112013001508A BR 112013001508 A2 BR112013001508 A2 BR 112013001508A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
solubility characteristics
enhanced solubility
enhanced
pharmaceutical
Prior art date
Application number
BR112013001508A
Other languages
English (en)
Inventor
Malay Ghosh
Masood A Chowhan
Vincent Nguyen
Way-Yu Lin
Wesley Wehsin Han
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of BR112013001508A2 publication Critical patent/BR112013001508A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BR112013001508A 2010-07-21 2011-07-20 composição farmacêutica com características de solubilidade intensificadas BR112013001508A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36632810P 2010-07-21 2010-07-21
PCT/US2011/044596 WO2012012476A1 (en) 2010-07-21 2011-07-20 Pharmaceutical composition with enhanced solubility characteristics

Publications (1)

Publication Number Publication Date
BR112013001508A2 true BR112013001508A2 (pt) 2016-06-07

Family

ID=44486435

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013001508A BR112013001508A2 (pt) 2010-07-21 2011-07-20 composição farmacêutica com características de solubilidade intensificadas

Country Status (11)

Country Link
US (1) US20120022149A1 (pt)
EP (1) EP2595603A1 (pt)
JP (2) JP2013535451A (pt)
KR (1) KR20130094293A (pt)
CN (1) CN103140215A (pt)
AU (1) AU2011282252B2 (pt)
BR (1) BR112013001508A2 (pt)
CA (1) CA2805656A1 (pt)
MX (1) MX2013000578A (pt)
WO (1) WO2012012476A1 (pt)
ZA (1) ZA201300098B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014117010A2 (en) * 2013-01-24 2014-07-31 Rigel Pharmaceuticals, Inc. Composition for ophthalmic administration

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501566A (ja) * 1984-03-14 1986-07-31 コルビエ−ル ジエロ−ム 有効成分の可溶化法およびそれにより得られる薬理組成物
US4728509A (en) * 1985-08-19 1988-03-01 Takeda Chemical Industries, Ltd. Aqueous liquid preparation
JPH01294620A (ja) * 1988-05-19 1989-11-28 Kissei Pharmaceut Co Ltd 水溶液製剤およびその製造方法
JPH07116029B2 (ja) * 1989-04-04 1995-12-13 キッセイ薬品工業株式会社 トラニラスト水溶液製剤
US5505953A (en) 1992-05-06 1996-04-09 Alcon Laboratories, Inc. Use of borate-polyol complexes in ophthalmic compositions
JPH0725769A (ja) * 1992-10-20 1995-01-27 Fuji Chem Ind Co Ltd アロプリノール医薬用液剤ならびにその製造法
JP3424038B2 (ja) * 1996-06-17 2003-07-07 株式会社日本点眼薬研究所 合成抗菌剤水性組成物
JP3410364B2 (ja) * 1997-05-14 2003-05-26 千寿製薬株式会社 ジフルプレドナート含有組成物
JP2000072672A (ja) * 1998-08-25 2000-03-07 Hoyu Co Ltd インドメタシン含有皮膚外用剤組成物
AU776789B2 (en) * 2000-01-25 2004-09-23 Alcon Inc. Ophthalmic anti-allergy compositions suitable for use with contact lenses
JP4541504B2 (ja) * 2000-06-14 2010-09-08 沢井製薬株式会社 トラニラストまたはその薬理学的に許容される塩を有効成分として含有する安定な水溶液製剤
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
JP3450805B2 (ja) * 2000-08-08 2003-09-29 わかもと製薬株式会社 水性医薬組成物
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
DE10132876A1 (de) * 2001-07-06 2003-01-30 Medproject Pharma Entwicklungs Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge
MXPA04008173A (es) * 2002-02-22 2004-11-26 Pharmacia Corp Formulaciones de farmaco antibiotico oftalmico que contienen un compuesto de ciclodextrina y cloruro de cetil piridinio.
JP5268231B2 (ja) * 2006-03-30 2013-08-21 小林製薬株式会社 水溶性高分子増粘剤を含有する組成物の安定化剤
US8782047B2 (en) * 2009-10-30 2014-07-15 Hitachi Data Systems Corporation Fixed content storage within a partitioned content platform using namespaces
US8377863B2 (en) * 2007-05-29 2013-02-19 Unigene Laboratories Inc. Peptide pharmaceutical for oral delivery
JP2010534201A (ja) * 2007-07-20 2010-11-04 アルコン,インコーポレイテッド 受容体チロシンキナーゼ阻害(RTKi)化合物の目への送達のための医薬製剤
US20100227917A1 (en) * 2007-09-06 2010-09-09 Masashi Nakakura EYE DROP CONTAINING DIBENZ[b,e]OXEPIN DERIVATIVE
ITMI20080289A1 (it) * 2008-02-22 2009-08-23 S I F I Societa Industria Farmaceutica Italia Composizioni di gemifloxacina con elevata efficacia su patologie oculari
TWI544927B (zh) * 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
US20090239836A1 (en) * 2008-03-24 2009-09-24 Mary Lee Ciolkowski Multifunctional Ophthalmic Compositions
JP2010037327A (ja) * 2008-07-07 2010-02-18 Wakamoto Pharmaceut Co Ltd ブリンゾラミド水性組成物
CN102159184B (zh) * 2008-10-09 2013-09-04 方济各安吉利克化学联合股份有限公司 含有对乙酰氨基酚的液体药物制剂
TW201023912A (en) * 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
ES2508290T3 (es) * 2009-03-03 2014-10-16 Alcon Research, Ltd. Composición farmacéutica para la administracón de compuestos de inhibición del receptor de tirosina cinasa (RTKI) al ojo

Also Published As

Publication number Publication date
MX2013000578A (es) 2013-02-21
AU2011282252B2 (en) 2014-08-21
US20120022149A1 (en) 2012-01-26
JP2016169237A (ja) 2016-09-23
JP2013535451A (ja) 2013-09-12
WO2012012476A1 (en) 2012-01-26
CA2805656A1 (en) 2012-01-26
KR20130094293A (ko) 2013-08-23
ZA201300098B (en) 2014-03-26
CN103140215A (zh) 2013-06-05
EP2595603A1 (en) 2013-05-29
AU2011282252A1 (en) 2013-02-07

Similar Documents

Publication Publication Date Title
SMT201700008B (it) Composizione farmaceutica
SMT201600350B (it) Composizioni farmaceutiche
SMT201700095B (is) Composizioni farmaceutiche per inalazione
DK3246018T3 (da) Farmaceutisk sammensætning
DK3097925T3 (da) Farmaceutisk sammensætning
BR112012031667A2 (pt) composição
BRPI1004940A2 (pt) composição farmacêutica
DK2640893T4 (da) Sammensætninger
DK3284467T3 (da) Nikotinholdige farmaceutiske sammensætninger
DK3257890T3 (da) Tværbindelig sammensætning
DK2632493T3 (da) Lægemiddelindgivelsessammensætninger
BR112013000980A2 (pt) Composições farmacêuticas com moduladores c- met
SMT201400069B (it) Formulazione farmaceutica
BR112012032683A2 (pt) composição
BRPI1012539A2 (pt) composições farmacêuticas
BRPI1015939A2 (pt) composição farmacêutica
EE201300005A (et) Ravimkoostis
DK2654736T3 (da) Hidtil ukendt farmaceutisk sammensætning
IT1394400B1 (it) Composizioni farmaceutiche
DK2391349T3 (da) Farmaceutisk sammensætning omfattende 2-oco-1-pyrrolidin-derivater
BRPI1009465A2 (pt) Formulação
BR112012032980A2 (pt) composição
UA21334S (uk) Цукерка
BR112013000356A2 (pt) formulação farmacêutica injetável de malfalano
CO6801722A2 (es) Composiciones farmacéuticas

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2471 DE 15-05-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.