BR112012029152A8 - Sistema de formação de imagem de autofoco para um microscópio, método para formação de iimagem de autofoco de um microscópio, meio legível por computador e elemento de programa para formação de imagem de autofoco de um microscópio - Google Patents

Sistema de formação de imagem de autofoco para um microscópio, método para formação de iimagem de autofoco de um microscópio, meio legível por computador e elemento de programa para formação de imagem de autofoco de um microscópio

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Publication number
BR112012029152A8
BR112012029152A8 BR112012029152A BR112012029152A BR112012029152A8 BR 112012029152 A8 BR112012029152 A8 BR 112012029152A8 BR 112012029152 A BR112012029152 A BR 112012029152A BR 112012029152 A BR112012029152 A BR 112012029152A BR 112012029152 A8 BR112012029152 A8 BR 112012029152A8
Authority
BR
Brazil
Prior art keywords
microscope
image formation
autofocus image
autofocus
computer readable
Prior art date
Application number
BR112012029152A
Other languages
English (en)
Other versions
BR112012029152A2 (pt
Inventor
Hulsken Bas
Stallinga Sjoerd
Original Assignee
Koninklijke Philips Electronics Nv
Koninklijke Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP10305559A external-priority patent/EP2390706A1/en
Application filed by Koninklijke Philips Electronics Nv, Koninklijke Philips Nv filed Critical Koninklijke Philips Electronics Nv
Publication of BR112012029152A2 publication Critical patent/BR112012029152A2/pt
Publication of BR112012029152A8 publication Critical patent/BR112012029152A8/pt

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/45—Cameras or camera modules comprising electronic image sensors; Control thereof for generating image signals from two or more image sensors being of different type or operating in different modes, e.g. with a CMOS sensor for moving images in combination with a charge-coupled device [CCD] for still images
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N23/00—Cameras or camera modules comprising electronic image sensors; Control thereof
    • H04N23/60—Control of cameras or camera modules
    • H04N23/67—Focus control based on electronic image sensor signals
    • H04N23/673—Focus control based on electronic image sensor signals based on contrast or high frequency components of image signals, e.g. hill climbing method
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N3/00—Scanning details of television systems; Combination thereof with generation of supply voltages
    • H04N3/10—Scanning details of television systems; Combination thereof with generation of supply voltages by means not exclusively optical-mechanical
    • H04N3/14—Scanning details of television systems; Combination thereof with generation of supply voltages by means not exclusively optical-mechanical by means of electrically scanned solid-state devices
    • H04N3/15—Scanning details of television systems; Combination thereof with generation of supply voltages by means not exclusively optical-mechanical by means of electrically scanned solid-state devices for picture signal generation
    • H04N3/1581—Scanning details of television systems; Combination thereof with generation of supply voltages by means not exclusively optical-mechanical by means of electrically scanned solid-state devices for picture signal generation using linear image-sensor
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N25/00—Circuitry of solid-state image sensors [SSIS]; Control thereof
    • H04N25/70—SSIS architectures; Circuits associated therewith
    • H04N25/701—Line sensors

Landscapes

  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Multimedia (AREA)
  • Signal Processing (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Human Computer Interaction (AREA)
  • Automatic Focus Adjustment (AREA)
  • Microscoopes, Condenser (AREA)

Abstract

SISTEMA DE FORMAÇÃO DE IMAGEM DE AUTOFOCO PARA UM MICROSCÓPIO, MÉTODO PARA FORMAÇÃO DE IMAGEM DE AUTOFOCO DE UM MICROSCÓPIO, MEIO LEGÍVEL POR COMPUTADOR, E ELEMENTO DE PROGRAMA PARA FORMAÇÃO DE IMAGEM DE AUTOFOCO DE UM MICROSCÓPIO. A presente invenção se refere ao campo de patologia digital e, em especial, aos scanners de lâmina integral. Formação de imagem de autofoco pode ser executada por amostragem de um primeiro número de pixels de um sensor de imagem primária e amostragem de um segundo número de pixels de um sensor de imagem de autofoco, em que o segundo número está entre um quarto e três quartos do primeiro número. Dessa maneira, autofoco contínuo para escaneamento de luz rápido pode ser provido com base em um sensor de imagem adicional que é inclinado em relação ao eixo óptico.
BR112012029152A 2010-05-18 2011-05-04 Sistema de formação de imagem de autofoco para um microscópio, método para formação de iimagem de autofoco de um microscópio, meio legível por computador e elemento de programa para formação de imagem de autofoco de um microscópio BR112012029152A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10305520 2010-05-18
EP10305559A EP2390706A1 (en) 2010-05-27 2010-05-27 Autofocus imaging.
PCT/IB2011/051963 WO2011145016A1 (en) 2010-05-18 2011-05-04 Autofocus imaging

Publications (2)

Publication Number Publication Date
BR112012029152A2 BR112012029152A2 (pt) 2017-12-12
BR112012029152A8 true BR112012029152A8 (pt) 2018-02-06

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012029152A BR112012029152A8 (pt) 2010-05-18 2011-05-04 Sistema de formação de imagem de autofoco para um microscópio, método para formação de iimagem de autofoco de um microscópio, meio legível por computador e elemento de programa para formação de imagem de autofoco de um microscópio

Country Status (6)

Country Link
US (3) US10061108B2 (pt)
EP (1) EP2572226A1 (pt)
JP (1) JP5809248B2 (pt)
CN (1) CN102893198B (pt)
BR (1) BR112012029152A8 (pt)
WO (1) WO2011145016A1 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012029152A8 (pt) * 2010-05-18 2018-02-06 Koninklijke Philips Electronics Nv Sistema de formação de imagem de autofoco para um microscópio, método para formação de iimagem de autofoco de um microscópio, meio legível por computador e elemento de programa para formação de imagem de autofoco de um microscópio
ES2953897T3 (es) 2012-05-02 2023-11-16 Leica Biosystems Imaging Inc Enfoque en tiempo real en imagenología de exploración lineal
EP2990850B1 (en) 2013-04-26 2020-09-16 Hamamatsu Photonics K.K. Image acquisition device and method and system for acquiring focusing information for specimen
CN105143952B (zh) * 2013-04-26 2018-09-28 浜松光子学株式会社 图像取得装置以及图像取得装置的聚焦方法
HUE052489T2 (hu) 2013-04-26 2021-04-28 Hamamatsu Photonics Kk Képfelvevõ berendezés és eljárás és rendszer fókusztérkép elõállítására minta számára
CN103399397B (zh) * 2013-07-19 2015-11-18 香港应用科技研究院有限公司 用于图像扫描系统的预测聚焦
CN103592754B (zh) * 2013-11-07 2016-03-09 麦克奥迪实业集团有限公司 一种数字切片实时扫描自动聚焦跟踪方法
KR102125561B1 (ko) 2013-12-03 2020-06-22 삼성전자주식회사 촬영 장치 및 이의 제어 방법
BR112017007137A2 (pt) * 2015-03-19 2017-12-19 Koninklijke Philips Nv scanner de patologia digital
WO2017053891A1 (en) 2015-09-24 2017-03-30 Leica Biosystems Imaging, Inc. Real-time focusing in line scan imaging
KR101898217B1 (ko) * 2016-12-29 2018-09-12 엘지디스플레이 주식회사 검사장비 및 이를 이용한 검사방법
NL2018853B1 (en) * 2017-05-05 2018-11-14 Illumina Inc Systems and methods for improved focus tracking using a hybrid mode light source
CN115061271B (zh) * 2017-09-29 2024-02-02 徕卡生物系统成像股份有限公司 实时自动对焦聚焦算法
US10146041B1 (en) * 2018-05-01 2018-12-04 Nanotronics Imaging, Inc. Systems, devices and methods for automatic microscope focus
US12057229B1 (en) 2018-11-08 2024-08-06 Dartmouth-Hitchcock Clinic System and method for analyzing cytological tissue preparations

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883689A (en) 1973-09-04 1975-05-13 Nasa Servo-controlled intravital microscope system
JPS6026311A (ja) 1983-07-22 1985-02-09 Nippon Kogaku Kk <Nikon> 暗視野顕微鏡用焦点検出装置
JPH02136845A (ja) 1988-11-18 1990-05-25 Canon Inc 画像読取装置
JPH08106040A (ja) 1994-10-04 1996-04-23 Tokuji Shibahara 位置検出装置
US6078681A (en) * 1996-03-18 2000-06-20 Marine Biological Laboratory Analytical imaging system and process
DE19746575A1 (de) 1997-10-22 1999-04-29 Zeiss Carl Fa Optische Bildaufnahmeeinrichtung und Verfahren zu deren Nutzung
US6917377B2 (en) * 2000-02-04 2005-07-12 Olympus Optical Co., Ltd. Microscope system
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US6855733B2 (en) 2001-01-24 2005-02-15 Soft Gel Technologies, Inc. Formulation and manufacturing process for coenzyme Q10 soft gel capsules
DE10306970B4 (de) * 2003-02-19 2017-02-09 Carl Zeiss Microscopy Gmbh Elektronisches Mikroskop
US7330574B2 (en) 2003-05-08 2008-02-12 Ometrix, Inc. Best-focus estimation by lateral scanning
US20050089208A1 (en) 2003-07-22 2005-04-28 Rui-Tao Dong System and method for generating digital images of a microscope slide
US7813579B2 (en) * 2004-05-24 2010-10-12 Hamamatsu Photonics K.K. Microscope system
US7232980B2 (en) * 2004-05-24 2007-06-19 Hamamatsu Photonics K.K. Microscope system
JP5403852B2 (ja) * 2005-08-12 2014-01-29 株式会社荏原製作所 検出装置及び検査装置
US7297910B2 (en) * 2005-12-30 2007-11-20 General Electric Company System and method for utilizing an autofocus feature in an automated microscope
DE102006027836B4 (de) * 2006-06-16 2020-02-20 Carl Zeiss Microscopy Gmbh Mikroskop mit Autofokuseinrichtung
US7576307B2 (en) * 2007-04-30 2009-08-18 General Electric Company Microscope with dual image sensors for rapid autofocusing
WO2008137746A1 (en) 2007-05-04 2008-11-13 Aperio Technologies, Inc. Rapid microscope scanner for volume image acquisition
US8681736B2 (en) 2007-09-04 2014-03-25 Telefonaktiebolaget L M Ericsson (Publ) Time-to-trigger handling methods and apparatus
US8711473B2 (en) 2007-09-14 2014-04-29 Olympus Corporation Focus adjustment unit and optical scanning microscope
US7667169B2 (en) * 2008-05-22 2010-02-23 Omnivision Technologies, Inc. Image sensor with simultaneous auto-focus and image preview
JP5035702B2 (ja) * 2009-02-27 2012-09-26 カシオ計算機株式会社 撮像装置、オートフォーカス方法及びプログラム
US10353190B2 (en) 2009-12-30 2019-07-16 Koninklijke Philips N.V. Sensor for microscopy
BR112012029152A8 (pt) * 2010-05-18 2018-02-06 Koninklijke Philips Electronics Nv Sistema de formação de imagem de autofoco para um microscópio, método para formação de iimagem de autofoco de um microscópio, meio legível por computador e elemento de programa para formação de imagem de autofoco de um microscópio

Also Published As

Publication number Publication date
BR112012029152A2 (pt) 2017-12-12
US20180203220A1 (en) 2018-07-19
CN102893198B (zh) 2015-11-25
JP2013531270A (ja) 2013-08-01
US20130057674A1 (en) 2013-03-07
CN102893198A (zh) 2013-01-23
EP2572226A1 (en) 2013-03-27
WO2011145016A1 (en) 2011-11-24
US20180210182A1 (en) 2018-07-26
US10371929B2 (en) 2019-08-06
JP5809248B2 (ja) 2015-11-10
US10061108B2 (en) 2018-08-28
US10365468B2 (en) 2019-07-30

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B25G Requested change of headquarter approved

Owner name: KONINKLIJKE PHILIPS N.V. (NL)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2513 DE 06-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B350 Update of information on the portal [chapter 15.35 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]