BR112012020700A8 - método de tratamento de pacientes diagnosticadas com câncer do ovário, kit de tratamento de câncer do ovário, método de instrução a uma paciente humana com câncer do ovário, método promocional e comercial - Google Patents
método de tratamento de pacientes diagnosticadas com câncer do ovário, kit de tratamento de câncer do ovário, método de instrução a uma paciente humana com câncer do ovário, método promocional e comercialInfo
- Publication number
- BR112012020700A8 BR112012020700A8 BR112012020700A BR112012020700A BR112012020700A8 BR 112012020700 A8 BR112012020700 A8 BR 112012020700A8 BR 112012020700 A BR112012020700 A BR 112012020700A BR 112012020700 A BR112012020700 A BR 112012020700A BR 112012020700 A8 BR112012020700 A8 BR 112012020700A8
- Authority
- BR
- Brazil
- Prior art keywords
- ovarian cancer
- promotional
- instruction
- treatment kit
- commercial
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- G—PHYSICS
- G06—COMPUTING OR CALCULATING; COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q99/00—Subject matter not provided for in other groups of this subclass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Business, Economics & Management (AREA)
- Physics & Mathematics (AREA)
- General Business, Economics & Management (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Cell Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30709510P | 2010-02-23 | 2010-02-23 | |
| US35123110P | 2010-06-03 | 2010-06-03 | |
| US36005910P | 2010-06-30 | 2010-06-30 | |
| US201161439819P | 2011-02-04 | 2011-02-04 | |
| PCT/US2011/025651 WO2011106300A2 (en) | 2010-02-23 | 2011-02-22 | Anti-angiogenesis therapy for the treatment of ovarian cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112012020700A2 BR112012020700A2 (pt) | 2017-03-21 |
| BR112012020700A8 true BR112012020700A8 (pt) | 2018-01-02 |
Family
ID=44476669
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012020700A BR112012020700A8 (pt) | 2010-02-23 | 2011-02-22 | método de tratamento de pacientes diagnosticadas com câncer do ovário, kit de tratamento de câncer do ovário, método de instrução a uma paciente humana com câncer do ovário, método promocional e comercial |
Country Status (20)
| Country | Link |
|---|---|
| US (8) | US8778340B2 (https=) |
| EP (3) | EP2539367A2 (https=) |
| JP (6) | JP2013520442A (https=) |
| KR (4) | KR102104197B1 (https=) |
| CN (3) | CN120733043A (https=) |
| AR (1) | AR080244A1 (https=) |
| AU (5) | AU2011221229B2 (https=) |
| BR (1) | BR112012020700A8 (https=) |
| CA (2) | CA2930248A1 (https=) |
| CL (1) | CL2012002326A1 (https=) |
| CO (1) | CO6592072A2 (https=) |
| IL (2) | IL221058B (https=) |
| MA (1) | MA34059B1 (https=) |
| MX (3) | MX369170B (https=) |
| PH (2) | PH12012501681A1 (https=) |
| RU (1) | RU2012140447A (https=) |
| SG (2) | SG10201401123VA (https=) |
| TW (2) | TWI619509B (https=) |
| UA (1) | UA114277C2 (https=) |
| WO (1) | WO2011106300A2 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8268314B2 (en) | 2008-10-08 | 2012-09-18 | Hoffmann-La Roche Inc. | Bispecific anti-VEGF/anti-ANG-2 antibodies |
| US9527925B2 (en) | 2011-04-01 | 2016-12-27 | Boehringer Ingelheim International Gmbh | Bispecific binding molecules binding to VEGF and ANG2 |
| LT3485903T (lt) | 2011-09-23 | 2023-02-27 | Mereo Biopharma 5, Inc. | Vegf/ dll4 surišantys agentai ir jų panaudojimas |
| WO2013135602A2 (en) | 2012-03-13 | 2013-09-19 | F. Hoffmann-La Roche Ag | Combination therapy for the treatment of ovarian cancer |
| LT3495387T (lt) | 2012-07-13 | 2021-11-25 | Roche Glycart Ag | Bispecifiniai anti-vegf / anti-ang-2 antikūnai ir jų panaudojimas akių kraujagyslių ligoms gydyti |
| SG11201500903XA (en) * | 2012-08-07 | 2015-03-30 | Genentech Inc | Combination therapy for the treatment of glioblastoma |
| US10456470B2 (en) | 2013-08-30 | 2019-10-29 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| US10617755B2 (en) | 2013-08-30 | 2020-04-14 | Genentech, Inc. | Combination therapy for the treatment of glioblastoma |
| US9676863B2 (en) | 2014-02-10 | 2017-06-13 | Merck Patent Gmbh | Targeted TGFβ inhibitors |
| US20170112866A1 (en) * | 2014-04-04 | 2017-04-27 | Taiho Pharmaceutical Company Limited | Anti-tumor agent containing taxane compound, and anti-tumor effect enhancer |
| CA2946906A1 (en) * | 2014-05-07 | 2015-11-12 | Medimmune, Llc | Methods of using anti-ang2 antibodies |
| US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
| WO2016011052A1 (en) | 2014-07-14 | 2016-01-21 | Genentech, Inc. | Diagnostic methods and compositions for treatment of glioblastoma |
| CN107106688A (zh) * | 2014-11-14 | 2017-08-29 | 豪夫迈·罗氏有限公司 | 预测对vegf拮抗剂的响应 |
| AU2016323968B2 (en) | 2015-09-17 | 2023-07-06 | Immunogen, Inc. | Therapeutic combinations comprising anti-FOLR1 immunoconjugates |
| EP3353204B1 (en) | 2015-09-23 | 2023-10-18 | Mereo BioPharma 5, Inc. | Bi-specific anti-vegf/dll4 antibody for use in treating platinum-resistant ovarian cancer |
| TW201713360A (en) * | 2015-10-06 | 2017-04-16 | Mayo Foundation | Methods of treating cancer using compositions of antibodies and carrier proteins |
| KR102799807B1 (ko) | 2015-12-30 | 2025-04-24 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
| US10618969B2 (en) | 2016-04-06 | 2020-04-14 | Mayo Foundation For Medical Education And Research | Carrier-binding agent compositions and methods of making and using the same |
| EP3272771A1 (en) * | 2016-07-22 | 2018-01-24 | Centre National De La Recherche Scientifique | Treatment for use for preventing metastasis in a subject exposed to cancer treatment inducing p38 activation |
| MX2020009152A (es) | 2018-03-02 | 2020-11-09 | Kodiak Sciences Inc | Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos. |
| CN112165957A (zh) * | 2018-03-26 | 2021-01-01 | 上海易乐生物技术有限公司 | proBDNF调节剂在B细胞相关疾病中的用途 |
| CA3157509A1 (en) | 2019-10-10 | 2021-04-15 | Kodiak Sciences Inc. | Methods of treating an eye disorder |
| US20240139316A1 (en) * | 2021-03-10 | 2024-05-02 | Canariabio Inc. | Use of oregovomab and bevacizumab, paclitaxel, carboplatin for treatment of brca-wild type platinum sensitive recurrent |
| CN113244388A (zh) * | 2021-07-01 | 2021-08-13 | 江苏先声药业有限公司 | 抗人vegf抗体与化药联用在制备治疗卵巢癌的药物中的应用 |
| EP4504260A1 (en) * | 2022-04-04 | 2025-02-12 | Merck Sharp & Dohme LLC | Methods for treating cancer, an infectious disease or an infection using a combination of a tigit antagonist, a pd-1 antagonist, and a vegf antagonist |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US991302A (en) * | 1910-03-28 | 1911-05-02 | Frederick G Hepburn | Waste-supporter. |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
| IL85035A0 (en) | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| WO1989006692A1 (en) | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
| ATE300615T1 (de) | 1990-08-29 | 2005-08-15 | Genpharm Int | Transgene mäuse fähig zur produktion heterologer antikörper |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| CA2405246A1 (en) | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with alterred binding properties |
| US20030206899A1 (en) | 1991-03-29 | 2003-11-06 | Genentech, Inc. | Vascular endothelial cell growth factor antagonists |
| US6582959B2 (en) | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| ES2136092T3 (es) | 1991-09-23 | 1999-11-16 | Medical Res Council | Procedimientos para la produccion de anticuerpos humanizados. |
| DE69232137T2 (de) | 1991-11-25 | 2002-05-29 | Enzon Inc | Multivalente antigen-bindende proteine |
| AU675929B2 (en) | 1992-02-06 | 1997-02-27 | Curis, Inc. | Biosynthetic binding protein for cancer marker |
| US5573905A (en) | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| BR9207175A (pt) | 1992-10-28 | 1995-12-12 | Genentech Inc | Composição contendo antagonista de fator de crescimento de célula endotelial vascular sequência aminoácida de anticorpo monoclonal polipeptídeo e método de tratamento de tumor em mamífero |
| MD1367C2 (ro) | 1992-11-13 | 2000-11-30 | Idec Pharmaceuticals Corporation | Metode de tratament al limfomului celulelor B, anticorpi anti-CD20, hibridom. |
| US5635388A (en) | 1994-04-04 | 1997-06-03 | Genentech, Inc. | Agonist antibodies against the flk2/flt3 receptor and uses thereof |
| IL117645A (en) | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
| US5641870A (en) | 1995-04-20 | 1997-06-24 | Genentech, Inc. | Low pH hydrophobic interaction chromatography for antibody purification |
| US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| CA2226575C (en) | 1995-07-27 | 2011-10-18 | Genentech, Inc. | Stabile isotonic lyophilized protein formulation |
| US5730977A (en) | 1995-08-21 | 1998-03-24 | Mitsui Toatsu Chemicals, Inc. | Anti-VEGF human monoclonal antibody |
| GB9603256D0 (en) | 1996-02-16 | 1996-04-17 | Wellcome Found | Antibodies |
| US6100071A (en) | 1996-05-07 | 2000-08-08 | Genentech, Inc. | Receptors as novel inhibitors of vascular endothelial growth factor activity and processes for their production |
| EP2338915A3 (en) | 1997-04-07 | 2011-10-12 | Genentech, Inc. | Anti-VEGF antibodies |
| US20020032315A1 (en) | 1997-08-06 | 2002-03-14 | Manuel Baca | Anti-vegf antibodies |
| JP3957765B2 (ja) | 1997-04-07 | 2007-08-15 | ジェネンテク・インコーポレイテッド | 抗vegf抗体 |
| US6884879B1 (en) | 1997-04-07 | 2005-04-26 | Genentech, Inc. | Anti-VEGF antibodies |
| ATE296315T1 (de) | 1997-06-24 | 2005-06-15 | Genentech Inc | Galactosylierte glykoproteine enthaltende zusammensetzungen und verfahren zur deren herstellung |
| WO1999022764A1 (en) | 1997-10-31 | 1999-05-14 | Genentech, Inc. | Methods and compositions comprising glycoprotein glycoforms |
| US6528624B1 (en) | 1998-04-02 | 2003-03-04 | Genentech, Inc. | Polypeptide variants |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| ES2292236T3 (es) | 1998-04-02 | 2008-03-01 | Genentech, Inc. | Variantes de anticuerpos y sus fragmentos. |
| US6242195B1 (en) | 1998-04-02 | 2001-06-05 | Genentech, Inc. | Methods for determining binding of an analyte to a receptor |
| ES2434961T5 (es) | 1998-04-20 | 2018-01-18 | Roche Glycart Ag | Ingeniería de glicosilación de anticuerpos para mejorar la citotoxicidad celular dependiente del anticuerpo |
| HU230769B1 (hu) | 1999-01-15 | 2018-03-28 | Genentech Inc. | Módosított effektor-funkciójú polipeptid-változatok |
| US6703020B1 (en) | 1999-04-28 | 2004-03-09 | Board Of Regents, The University Of Texas System | Antibody conjugate methods for selectively inhibiting VEGF |
| EP2180054A1 (en) | 1999-12-24 | 2010-04-28 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| CN101289511A (zh) | 2000-04-11 | 2008-10-22 | 杰南技术公司 | 多价抗体及其应用 |
| PT1355919E (pt) | 2000-12-12 | 2011-03-02 | Medimmune Llc | Moléculas com semivida longa, composições que as contêm e suas utilizações |
| EP2180044A1 (en) | 2001-08-03 | 2010-04-28 | GlycArt Biotechnology AG | Antibody glycosylation variants having increased anti-body-dependent cellular cytotoxicity |
| HUP0600342A3 (en) | 2001-10-25 | 2011-03-28 | Genentech Inc | Glycoprotein compositions |
| US20040093621A1 (en) | 2001-12-25 | 2004-05-13 | Kyowa Hakko Kogyo Co., Ltd | Antibody composition which specifically binds to CD20 |
| US7361740B2 (en) | 2002-10-15 | 2008-04-22 | Pdl Biopharma, Inc. | Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis |
| MXPA05012723A (es) * | 2003-05-30 | 2006-02-08 | Genentech Inc | Tratamiento con anticuerpos anti-vgf. |
| US20050106667A1 (en) | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| WO2005044853A2 (en) | 2003-11-01 | 2005-05-19 | Genentech, Inc. | Anti-vegf antibodies |
| SV2006002143A (es) * | 2004-06-16 | 2006-01-26 | Genentech Inc | Uso de un anticuerpo para el tratamiento del cancer resistente al platino |
| US20060009360A1 (en) | 2004-06-25 | 2006-01-12 | Robert Pifer | New adjuvant composition |
| RS52213B (sr) | 2004-09-03 | 2012-10-31 | Genentech, Inc. | Humanizovani anti-beta7 antagonisti i njihove primene |
| US20070166388A1 (en) * | 2005-02-18 | 2007-07-19 | Desai Neil P | Combinations and modes of administration of therapeutic agents and combination therapy |
| CN101889025B (zh) * | 2007-10-30 | 2013-11-13 | 健泰科生物技术公司 | 通过阳离子交换层析进行的抗体纯化 |
| KR101807319B1 (ko) | 2008-11-22 | 2017-12-11 | 제넨테크, 인크. | 유방암의 치료를 위한, 화학요법과 조합된 항-vegf 항체의 용도 |
-
2011
- 2011-02-22 KR KR1020187035833A patent/KR102104197B1/ko not_active Ceased
- 2011-02-22 EP EP11706712A patent/EP2539367A2/en not_active Ceased
- 2011-02-22 CN CN202510798991.0A patent/CN120733043A/zh active Pending
- 2011-02-22 CN CN201910288567.6A patent/CN110227154A/zh active Pending
- 2011-02-22 SG SG10201401123VA patent/SG10201401123VA/en unknown
- 2011-02-22 KR KR1020187006794A patent/KR20180028561A/ko not_active Ceased
- 2011-02-22 US US13/032,532 patent/US8778340B2/en active Active
- 2011-02-22 EP EP16159080.7A patent/EP3064509A3/en not_active Ceased
- 2011-02-22 KR KR1020197037761A patent/KR20190143480A/ko not_active Ceased
- 2011-02-22 JP JP2012554084A patent/JP2013520442A/ja not_active Withdrawn
- 2011-02-22 AR ARP110100537A patent/AR080244A1/es unknown
- 2011-02-22 KR KR1020127021909A patent/KR101839161B1/ko not_active Ceased
- 2011-02-22 AU AU2011221229A patent/AU2011221229B2/en active Active
- 2011-02-22 CN CN2011800204179A patent/CN103237810A/zh active Pending
- 2011-02-22 WO PCT/US2011/025651 patent/WO2011106300A2/en not_active Ceased
- 2011-02-22 UA UAA201211033A patent/UA114277C2/uk unknown
- 2011-02-22 MA MA35198A patent/MA34059B1/fr unknown
- 2011-02-22 TW TW103134046A patent/TWI619509B/zh active
- 2011-02-22 EP EP20162926.8A patent/EP3696194A1/en not_active Withdrawn
- 2011-02-22 MX MX2016010753A patent/MX369170B/es unknown
- 2011-02-22 TW TW100105846A patent/TWI457135B/zh active
- 2011-02-22 BR BR112012020700A patent/BR112012020700A8/pt not_active Application Discontinuation
- 2011-02-22 CA CA2930248A patent/CA2930248A1/en not_active Withdrawn
- 2011-02-22 MX MX2012009554A patent/MX2012009554A/es not_active Application Discontinuation
- 2011-02-22 SG SG2012061644A patent/SG183414A1/en unknown
- 2011-02-22 CA CA2787952A patent/CA2787952C/en active Active
- 2011-02-22 RU RU2012140447/15A patent/RU2012140447A/ru not_active Application Discontinuation
- 2011-02-22 PH PH1/2012/501681A patent/PH12012501681A1/en unknown
-
2012
- 2012-07-22 IL IL221058A patent/IL221058B/en active IP Right Grant
- 2012-08-01 CO CO12129535A patent/CO6592072A2/es unknown
- 2012-08-16 MX MX2019000425A patent/MX2019000425A/es unknown
- 2012-08-22 CL CL2012002326A patent/CL2012002326A1/es unknown
-
2013
- 2013-04-26 JP JP2013094727A patent/JP6184733B2/ja active Active
-
2014
- 2014-01-16 US US14/157,351 patent/US20140178371A1/en not_active Abandoned
-
2015
- 2015-08-03 JP JP2015153726A patent/JP2016020354A/ja not_active Withdrawn
- 2015-08-10 AU AU2015210479A patent/AU2015210479A1/en not_active Abandoned
-
2016
- 2016-06-16 US US15/184,332 patent/US20160279241A1/en not_active Abandoned
- 2016-09-01 PH PH12016501728A patent/PH12016501728A1/en unknown
-
2017
- 2017-01-31 US US15/421,184 patent/US20170143826A1/en not_active Abandoned
- 2017-05-10 JP JP2017094206A patent/JP2017193551A/ja active Pending
- 2017-06-26 AU AU2017204320A patent/AU2017204320B2/en active Active
-
2018
- 2018-04-10 IL IL258612A patent/IL258612B/en unknown
- 2018-07-30 JP JP2018142978A patent/JP2018199683A/ja not_active Withdrawn
- 2018-08-09 US US16/059,964 patent/US20180344847A1/en not_active Abandoned
-
2019
- 2019-05-17 AU AU2019203466A patent/AU2019203466A1/en not_active Abandoned
- 2019-07-29 AU AU2019210484A patent/AU2019210484A1/en not_active Abandoned
-
2020
- 2020-05-13 US US15/930,798 patent/US20210052728A1/en not_active Abandoned
- 2020-07-27 JP JP2020126490A patent/JP2020196719A/ja active Pending
-
2023
- 2023-01-04 US US18/149,972 patent/US20230226179A1/en not_active Abandoned
-
2024
- 2024-11-13 US US18/946,554 patent/US20250177522A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112012020700A8 (pt) | método de tratamento de pacientes diagnosticadas com câncer do ovário, kit de tratamento de câncer do ovário, método de instrução a uma paciente humana com câncer do ovário, método promocional e comercial | |
| ZA201300218B (en) | Treatment of blood cancer | |
| BR112013002644A2 (pt) | método de enxertia de pele e método de tratamento de vitiligo | |
| EP2563303A4 (en) | METHOD AND APPARATUS FOR TREATING OCULAR TISSUE USING COMBINED MODALITIES | |
| EP2605827A4 (en) | NON-INVASIVE TREATMENT OF BRONCHOCONSTRICTION | |
| PT2766014T (pt) | Métodos de tratar pacientes pediátricos utilizando dexmedetomidina | |
| PT2640375T (pt) | Método de tratamento da nefropatia induzida por contraste | |
| EP2793993A4 (en) | RECOVERY AND PROCESSING OF HUMAN IN VIVO EMBRYOS | |
| IL226446A0 (en) | פילופ@בסרטן@her@@עבודקי@עם@פקליטאקסל@וטרסצוזומאב–mcc–dm | |
| PL2552438T3 (pl) | Sposoby leczenia raka wątrobowokomórkowego | |
| EP2729180A4 (en) | METAL-BISPHOSPHONATE NANOPARTICLES FOR ANTICANCER THERAPY AND IMAGING, AND FOR TREATING BONE DISORDERS | |
| EP2613786A4 (en) | TREATMENT OF DISEASES | |
| LT3778885T (lt) | Dirbtinai sukurtų žmogaus arginazių kompozicijos ir vėžio gydymo metodai | |
| EP2613795A4 (en) | TREATMENT OF DISEASES | |
| BRPI0821779A2 (pt) | tratamento terapêutico de câncer | |
| PL2582683T3 (pl) | Leczenie dny moczanowej i hiperurykemii | |
| BR112012029746A2 (pt) | composição para tratamento da pele, método para fornecer um efeito microbicida para pele e uso de uma combinação | |
| EP2125002A4 (en) | TREATMENT OF SKIN CANCER | |
| FI20135146L (fi) | Farmaseuttiset koostumukset ja hoitomenetelmät | |
| IL236021A0 (en) | Method and system for treating biological tissue | |
| BR112013014597A2 (pt) | método de tratamento da pele com moduladores microrna | |
| EP2544655A4 (en) | COMPOSITIONS AND METHOD FOR SKIN TREATMENT | |
| GB201005662D0 (en) | Phototherapeutic treatment of acne | |
| BR112012033162A2 (pt) | método de identificação de pacientes, método de previsão da capacidade de reação de pacientes, método de determinação da probabilidade de um paciente com câncer exibir benefícios de terapia anticâncer, método de otimização da eficácia terapêutica, método de tratamento de câncer, kit e conjunto de compostos | |
| BR112014012495A2 (pt) | método in vitro, kit, inibidor de egfr e método de tratamento de pacientes afetados com câncer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B12B | Appeal against refusal [chapter 12.2 patent gazette] |