BR112012017532A2 - "método para determinar um polipeptídeo com uma sequência de aminoácidos mutante, para produzir um poliptedo e uma imunoglobulina" - Google Patents
"método para determinar um polipeptídeo com uma sequência de aminoácidos mutante, para produzir um poliptedo e uma imunoglobulina"Info
- Publication number
- BR112012017532A2 BR112012017532A2 BR112012017532A BR112012017532A BR112012017532A2 BR 112012017532 A2 BR112012017532 A2 BR 112012017532A2 BR 112012017532 A BR112012017532 A BR 112012017532A BR 112012017532 A BR112012017532 A BR 112012017532A BR 112012017532 A2 BR112012017532 A2 BR 112012017532A2
- Authority
- BR
- Brazil
- Prior art keywords
- polypeptide
- immunoglobulin
- determining
- produce
- amino acid
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10001645 | 2010-02-18 | ||
PCT/EP2011/052282 WO2011101370A1 (en) | 2010-02-18 | 2011-02-16 | Method for the determination of sequence variants of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012017532A2 true BR112012017532A2 (pt) | 2019-09-24 |
Family
ID=42224873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012017532A BR112012017532A2 (pt) | 2010-02-18 | 2011-02-16 | "método para determinar um polipeptídeo com uma sequência de aminoácidos mutante, para produzir um poliptedo e uma imunoglobulina" |
Country Status (12)
Country | Link |
---|---|
US (3) | US20120322093A1 (pt) |
EP (1) | EP2537035B1 (pt) |
JP (1) | JP5903051B2 (pt) |
KR (1) | KR20120120500A (pt) |
CN (1) | CN102762987B (pt) |
BR (1) | BR112012017532A2 (pt) |
CA (1) | CA2787898A1 (pt) |
ES (1) | ES2609669T3 (pt) |
MX (1) | MX2012009538A (pt) |
RU (1) | RU2012138298A (pt) |
SG (2) | SG10201501080VA (pt) |
WO (1) | WO2011101370A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6132073B2 (ja) * | 2014-06-24 | 2017-05-24 | 株式会社島津製作所 | 包括的2次元クロマトグラフ用データ処理装置 |
US10781484B1 (en) | 2015-09-30 | 2020-09-22 | Agilent Technologies, Inc. | Method of oligonucleotide analysis |
CN110418849A (zh) * | 2017-02-03 | 2019-11-05 | 隆扎有限公司 | 分析多个细胞和检测生物产品制造中的蛋白质序列变体的方法 |
WO2019051103A1 (en) * | 2017-09-06 | 2019-03-14 | Lawrence Livermore National Security, Llc | METHODS AND SYSTEMS FOR EXECUTING GENETICALLY MODIFIED PROTEIN ANALYSIS, AND ASSOCIATED MARKER PROTEIN GENETIC VARIATIONS AND DATABASES |
JP7135561B2 (ja) * | 2018-08-08 | 2022-09-13 | 株式会社島津製作所 | 分析制御装置、分析システムおよび分析方法 |
JP6996451B2 (ja) * | 2018-08-24 | 2022-01-17 | 株式会社島津製作所 | 分析支援装置および分析支援方法 |
US11726096B2 (en) * | 2018-10-04 | 2023-08-15 | Regeneron Pharmaceuticals, Inc. | Fast protein sequencing |
CN113406336A (zh) * | 2021-06-15 | 2021-09-17 | 上海君谊生物科技有限公司 | 一种适用于质谱鉴定的毛干蛋白质提取方法及其应用 |
US20230243843A1 (en) * | 2022-01-10 | 2023-08-03 | Regeneron Pharmaceuticals, Inc. | Sequence variance analysis by proteominer |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2114168A1 (en) * | 1993-03-05 | 1994-09-06 | Zlatko Dembic | Chimeric human interferon-gamma-receptor/immunoglobulin polypeptides |
US7158862B2 (en) * | 2000-06-12 | 2007-01-02 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Method and system for mining mass spectral data |
CN1376692A (zh) * | 2001-03-22 | 2002-10-30 | 上海博德基因开发有限公司 | 一种多肽——免疫球蛋白轻链κ1蛋白-26.07和编码这种多肽的多核苷酸 |
US20030129760A1 (en) * | 2001-11-13 | 2003-07-10 | Aguilera Frank Reinaldo Morales | Mass intensity profiling system and uses thereof |
JP2005510732A (ja) * | 2001-11-30 | 2005-04-21 | ヨーロピアン モレキュラー バイオロジー ラボラトリー | 質量分析法によって自動的にタンパク質の配列決定を行うシステムおよび方法 |
CA2507189C (en) * | 2002-11-27 | 2018-06-12 | Sequenom, Inc. | Fragmentation-based methods and systems for sequence variation detection and discovery |
CN100383244C (zh) * | 2003-01-07 | 2008-04-23 | 西福根有限公司 | 用于生产重组多克隆蛋白质的方法 |
GB0308202D0 (en) * | 2003-04-09 | 2003-05-14 | King S College London | A screening method using mass spectrometry |
ATE510025T1 (de) * | 2005-12-13 | 2011-06-15 | Inst Curie | Verfahren für die detektion von mutationen in nukleinsaüren, und die anwendung in der diagnose von genetischen krankheiten und krebs |
-
2011
- 2011-02-16 ES ES11704217.6T patent/ES2609669T3/es active Active
- 2011-02-16 US US13/579,402 patent/US20120322093A1/en not_active Abandoned
- 2011-02-16 WO PCT/EP2011/052282 patent/WO2011101370A1/en active Application Filing
- 2011-02-16 SG SG10201501080VA patent/SG10201501080VA/en unknown
- 2011-02-16 JP JP2012552430A patent/JP5903051B2/ja active Active
- 2011-02-16 CA CA2787898A patent/CA2787898A1/en not_active Abandoned
- 2011-02-16 RU RU2012138298/15A patent/RU2012138298A/ru unknown
- 2011-02-16 BR BR112012017532A patent/BR112012017532A2/pt not_active IP Right Cessation
- 2011-02-16 MX MX2012009538A patent/MX2012009538A/es not_active Application Discontinuation
- 2011-02-16 EP EP11704217.6A patent/EP2537035B1/en active Active
- 2011-02-16 KR KR1020127021621A patent/KR20120120500A/ko not_active Application Discontinuation
- 2011-02-16 SG SG2012060265A patent/SG183320A1/en unknown
- 2011-02-16 CN CN201180010053.6A patent/CN102762987B/zh active Active
-
2014
- 2014-07-31 US US14/448,887 patent/US20150064735A1/en not_active Abandoned
-
2021
- 2021-06-15 US US17/348,084 patent/US20210371897A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2537035A1 (en) | 2012-12-26 |
WO2011101370A1 (en) | 2011-08-25 |
RU2012138298A (ru) | 2014-03-27 |
US20210371897A1 (en) | 2021-12-02 |
EP2537035B1 (en) | 2016-11-16 |
ES2609669T3 (es) | 2017-04-21 |
JP2013519099A (ja) | 2013-05-23 |
CN102762987A (zh) | 2012-10-31 |
JP5903051B2 (ja) | 2016-04-13 |
US20120322093A1 (en) | 2012-12-20 |
CA2787898A1 (en) | 2011-08-25 |
US20150064735A1 (en) | 2015-03-05 |
CN102762987B (zh) | 2016-03-30 |
SG10201501080VA (en) | 2015-04-29 |
MX2012009538A (es) | 2012-08-31 |
SG183320A1 (en) | 2012-09-27 |
KR20120120500A (ko) | 2012-11-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112012017532A2 (pt) | "método para determinar um polipeptídeo com uma sequência de aminoácidos mutante, para produzir um poliptedo e uma imunoglobulina" | |
IL224441B (en) | Antibodies with modified isoelectric points | |
ZA201308251B (en) | Amino acid sequence presenting fusion polypeptide and its use | |
IL222507A0 (en) | Heterodimeric antibody fc-containing proteins and methods for production thereof | |
HK1200851A1 (en) | Etanercept formulations stabilized with amino acids | |
EP2583973A4 (en) | PROCESS FOR CLEANING PROTEINS WITH AMINO ACIDS | |
BR112012022046A2 (pt) | ''anticorpo,composição farmacêutica,ácido nucleico ,vetores de expressão,célula hospedeira e método para a produção de um anticorpo recombinante''. | |
IL225538A0 (en) | Methods for the identification of anti-immune reaction peptides of anti-citrullinates | |
BR112012002137A2 (pt) | método para um polipeptídeo e/ou vírus de interesse em uma cultura de célula contínua,e, composição | |
BR112014028588A2 (pt) | métodos de incorporação de um aminoácido que compreende um grupo bcn em um polipeptídeo usando um códon ortogonal que codifica o mesmo e uma sintase pylrs ortogona. | |
HK1215954A1 (zh) | 蛋白、核酸、和抗體及其用途 | |
BR112013014912A2 (pt) | micro-organismo recombinante, zymomonas recombinante, polipeptídeo, métodos para a produção de uma zymomonas recombinantes produtora de etanol e para a produção de etanol | |
EP2651411A4 (en) | METHOD AND COMPOSITION FOR IMPROVED F-18 MARKING OF PROTEINS, PEPTIDES AND OTHER MOLECULES | |
BR112012004697B8 (pt) | método para purificar um polipeptídeo compreendendo uma região ch2/ch3 | |
BR112012031989A2 (pt) | ''método para produção de uma mistura de gasolina/butanol, mistura de gasolina/butanol e método para identificar uma mistura de gasolina'' | |
IL235994A0 (en) | Humanized anti-trka antibodies with amino acid substitutions | |
BR112012015818A2 (pt) | ''método para determinação de referência de tempo de enlace descendente e terminal'' | |
BR112013007237A2 (pt) | ''método para produzir um anticorpo anti-ig-1r'' | |
SG10201502139XA (en) | Method of Producing Recombinant Proteins with Mannose-Terminated N-Glycans | |
BR112012030941A2 (pt) | proteína de fusão tendo atividade de fator vii | |
BR112013014103A2 (pt) | método para produzir um l-aminoácido | |
BR112013012422A2 (pt) | "método para produzir uma preparação de anticorpo e anticorpo anti-her2" | |
DK2721152T3 (da) | Dimere bindingsproteiner baseret på modificerede ubiquitiner | |
EP2576587A4 (en) | MUTANT NGAL PROTEINS AND USES THEREOF | |
BR112013015882A2 (pt) | "célula de mycobacterium recombinante, método para gerar uma resposta imune th17 e uso de uma molécula de ácido nucleico recombinante" |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |