BR112012016742A2 - metodos para tratamento de cancer pancreatico - Google Patents

metodos para tratamento de cancer pancreatico

Info

Publication number
BR112012016742A2
BR112012016742A2 BR112012016742A BR112012016742A BR112012016742A2 BR 112012016742 A2 BR112012016742 A2 BR 112012016742A2 BR 112012016742 A BR112012016742 A BR 112012016742A BR 112012016742 A BR112012016742 A BR 112012016742A BR 112012016742 A2 BR112012016742 A2 BR 112012016742A2
Authority
BR
Brazil
Prior art keywords
pancreatic cancer
cancer treatment
treatment methods
methods
treating pancreatic
Prior art date
Application number
BR112012016742A
Other languages
English (en)
Inventor
Joubert Dominique
Hollande Frederic
Houhou Leila
Original Assignee
Biorealites S A S
Centre Nat Rech Scient
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biorealites S A S, Centre Nat Rech Scient, Inst Nat Sante Rech Med filed Critical Biorealites S A S
Publication of BR112012016742A2 publication Critical patent/BR112012016742A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

métodos para tratamento de câncer pancreático. a presente invenção refere-se a métodos de tratamento de câncer pancreático em indivíduos usando câncer com anticorpos que se ligam especificamente a progastrina.
BR112012016742A 2010-01-08 2011-01-07 metodos para tratamento de cancer pancreatico BR112012016742A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29361210P 2010-01-08 2010-01-08
PCT/EP2011/000049 WO2011083091A2 (en) 2010-01-08 2011-01-07 Methods for treating pancreatic cancer

Publications (1)

Publication Number Publication Date
BR112012016742A2 true BR112012016742A2 (pt) 2018-05-15

Family

ID=43607948

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112012016742A BR112012016742A2 (pt) 2010-01-08 2011-01-07 metodos para tratamento de cancer pancreatico
BR112012016820A BR112012016820A2 (pt) 2010-01-08 2011-01-07 Metodos para tratamento de cancer de seio

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112012016820A BR112012016820A2 (pt) 2010-01-08 2011-01-07 Metodos para tratamento de cancer de seio

Country Status (15)

Country Link
US (2) US9487582B2 (pt)
EP (2) EP2542584B8 (pt)
JP (2) JP5572718B2 (pt)
KR (2) KR101468397B1 (pt)
CN (2) CN102892784B (pt)
AU (2) AU2011204653B2 (pt)
BR (2) BR112012016742A2 (pt)
CA (2) CA2786479C (pt)
EA (2) EA025329B1 (pt)
ES (2) ES2657246T3 (pt)
NZ (2) NZ601591A (pt)
PL (2) PL2542584T3 (pt)
SG (2) SG182331A1 (pt)
WO (2) WO2011083090A2 (pt)
ZA (2) ZA201205004B (pt)

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WO2008076454A1 (en) 2006-12-19 2008-06-26 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
KR101576174B1 (ko) * 2010-07-26 2015-12-09 르 라보레또레 쎄르비에르 간암 요법을 위한 방법 및 조성물
US11078286B2 (en) 2015-09-20 2021-08-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibodies specific for fibroblast growth factor receptor 4 (FGFR4) and methods of their use
CN114705858A (zh) * 2015-12-31 2022-07-05 Syncerus有限责任公司 用于评估癌症发生的风险的组合物和方法
JP7018885B2 (ja) 2015-12-31 2022-02-14 プロガストリン、エ、カンセル、エス、アー エル、エル 食道癌の検出および治療のための組成物および方法
US20190011449A1 (en) * 2015-12-31 2019-01-10 Progastrine Et Cancers S.À R.L. Compositions and methods for detecting and treating gastric cancer
EA037015B1 (ru) * 2015-12-31 2021-01-27 Прогастрин Э Кансер С.А Р.Л. Применение и способ для профилактики или лечения рака яичников с использованием композиции, содержащей прогастринсвязывающее антитело
CN110402143B (zh) * 2017-01-06 2022-11-22 雷莫内克斯生物制药有限公司 预防或治疗转移性卵巢癌、子宫内膜癌或乳腺癌的组合物
KR102351556B1 (ko) 2017-03-30 2022-01-14 프로가스트린 에 캔서스 에스.에이 알.엘. 프로가스트린 결합 분자를 사용하는 전립선암의 검출 및 치료를 위한 조성물 및 방법
KR102616819B1 (ko) * 2017-03-30 2023-12-21 프로가스트린 에 캔서스 에스.에이 알.엘. 폐암을 치료하기 위한 조성물 및 방법
US11267881B2 (en) 2017-09-14 2022-03-08 Charles ROSSER Compositions and methods for treatment of diseases involving CXCL1 function
WO2019110662A1 (en) * 2017-12-05 2019-06-13 Progastrine Et Cancers S.À R.L. Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer
CN112004560A (zh) 2017-12-08 2020-11-27 Ecs生物识别系统有限公司 癌症诊断中的放射性标记的前胃液素
TW201940881A (zh) 2018-01-26 2019-10-16 瑞士商Ｅｃｓ前胃泌激素公司 在癌症診斷中結合前胃泌激素檢測與其他癌症生物標記的技術
EP3759492A1 (en) 2018-02-27 2021-01-06 ECS-Progastrin SA Progastrin as a biomarker for immunotherapy
JP7433236B2 (ja) * 2018-03-13 2024-02-19 フェインズ セラピューティクス，インコーポレーテッド 抗葉酸受容体１抗体及びその使用
CN108864255B (zh) * 2018-06-21 2022-01-04 天津医科大学肿瘤医院 一种乳腺癌干细胞特异性结合多肽及其在制备治疗乳腺癌药物中的应用
WO2020160022A1 (en) * 2019-01-28 2020-08-06 Rosser Charles J Compositions and methods for treatment of diseases involving cxcl1 function

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Also Published As

Publication number Publication date
WO2011083091A8 (en) 2012-08-09
WO2011083090A2 (en) 2011-07-14
ES2657246T3 (es) 2018-03-02
PL2542584T3 (pl) 2018-04-30
EP2542584A2 (en) 2013-01-09
SG182331A1 (en) 2012-08-30
KR20120135401A (ko) 2012-12-13
WO2011083090A3 (en) 2011-10-06
US20110177062A1 (en) 2011-07-21
AU2011204653A1 (en) 2012-07-26
SG182334A1 (en) 2012-08-30
EP2542583A2 (en) 2013-01-09
KR101438362B1 (ko) 2014-09-05
JP5572718B2 (ja) 2014-08-13
WO2011083091A3 (en) 2011-09-09
ZA201205004B (en) 2013-09-25
EA025329B1 (ru) 2016-12-30
JP2013516439A (ja) 2013-05-13
EA201200999A1 (ru) 2013-02-28
WO2011083091A2 (en) 2011-07-14
CA2786435C (en) 2017-01-17
CA2786479A1 (en) 2011-07-14
CA2786479C (en) 2016-03-15
AU2011204654A1 (en) 2012-07-26
US20110171213A1 (en) 2011-07-14
US8900588B2 (en) 2014-12-02
CN102933603B (zh) 2016-01-20
EP2542583B8 (en) 2017-12-13
JP6134141B2 (ja) 2017-05-24
NZ601588A (en) 2014-07-25
KR20130028050A (ko) 2013-03-18
KR101468397B1 (ko) 2014-12-04
EP2542584B8 (en) 2017-12-13
PL2542583T3 (pl) 2018-04-30
NZ601591A (en) 2015-01-30
BR112012016820A2 (pt) 2023-11-28
ZA201205003B (en) 2013-09-25
CN102892784B (zh) 2016-06-22
ES2657245T3 (es) 2018-03-02
AU2011204654B2 (en) 2014-04-10
CN102933603A (zh) 2013-02-13
EP2542584B1 (en) 2017-10-25
EA023722B1 (ru) 2016-07-29
CN102892784A (zh) 2013-01-23
EA201200998A1 (ru) 2013-02-28
US9487582B2 (en) 2016-11-08
CA2786435A1 (en) 2011-07-14
EP2542583B1 (en) 2017-10-25
JP2013516438A (ja) 2013-05-13
AU2011204653B2 (en) 2014-04-10

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]

Free format text: NOTIFICACAO DE DEVOLUCAO DO PEDIDO EM FUNCAO DA REVOGACAO DO ART. 229-C DA LEI NO 9.279, DE 1996, POR FORCA DA LEI NO 14.195, DE 2021

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements