BR112012014762A2 - forma polimorfa de nevirapina e sua preparação - Google Patents

forma polimorfa de nevirapina e sua preparação

Info

Publication number
BR112012014762A2
BR112012014762A2 BR112012014762A BR112012014762A BR112012014762A2 BR 112012014762 A2 BR112012014762 A2 BR 112012014762A2 BR 112012014762 A BR112012014762 A BR 112012014762A BR 112012014762 A BR112012014762 A BR 112012014762A BR 112012014762 A2 BR112012014762 A2 BR 112012014762A2
Authority
BR
Brazil
Prior art keywords
nevirapine
preparation
polymorphic form
unsolvated
relates
Prior art date
Application number
BR112012014762A
Other languages
English (en)
Inventor
Mino Rodolfo Caira
Nicole Stieger
Wilna Liebenberg
Original Assignee
Univ Northwest
Univ Cape Town
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Northwest, Univ Cape Town filed Critical Univ Northwest
Publication of BR112012014762A2 publication Critical patent/BR112012014762A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)

Abstract

patente de invenção: forma polimorfa de nevirapina e sua preparação. a invenção refere-se a um forma cristalina não solvatada metastável (forma-iv) de nevirapina, tendo pelo menos um pico de difração em pó de raio-x característico em aproximadamente 7, 1° a 7,5° dois teta. a invenção ainda se refere a um método de preparação da produção de uma forma não solvatada anidra particulada de nevirapina.
BR112012014762A 2009-12-17 2010-12-14 forma polimorfa de nevirapina e sua preparação BR112012014762A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200908990 2009-12-17
PCT/IB2010/055808 WO2011073907A1 (en) 2009-12-17 2010-12-14 A polymorph form of nevirapine and its preparation

Publications (1)

Publication Number Publication Date
BR112012014762A2 true BR112012014762A2 (pt) 2016-03-29

Family

ID=43795151

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014762A BR112012014762A2 (pt) 2009-12-17 2010-12-14 forma polimorfa de nevirapina e sua preparação

Country Status (5)

Country Link
CN (1) CN102725293A (pt)
BR (1) BR112012014762A2 (pt)
DE (1) DE112010004862T5 (pt)
WO (1) WO2011073907A1 (pt)
ZA (1) ZA201204410B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9273049B2 (en) * 2009-11-10 2016-03-01 North-West University Method for increasing the solubility of nevirapine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366972A (en) 1989-04-20 1994-11-22 Boehringer Ingelheim Pharmaceuticals, Inc. 5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection
DE4403311C1 (de) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
RU2196584C2 (ru) * 1997-08-25 2003-01-20 Берингер Ингельхайм Фармасьютикельс, Инк. Фармацевтическая суспензия, содержащая невирапин-полугидрат
US20050059653A1 (en) 2002-06-21 2005-03-17 Dr. Reddy's Laboratories Limited Novel crystalline forms of 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido [3,2-b: 2',3'-e][1,4] diazepin-6-one (nevirapine)
UA80140C2 (en) * 2002-06-28 2007-08-27 Boehringer Ingelheim Chemicals Improved method of making nevirapine, intermediate (variants)
WO2007010352A1 (en) * 2005-07-19 2007-01-25 Emcure Pharmaceuticals Limited An improved process for industrial manufacture of nevirapine

Also Published As

Publication number Publication date
CN102725293A (zh) 2012-10-10
WO2011073907A1 (en) 2011-06-23
DE112010004862T5 (de) 2012-12-06
ZA201204410B (en) 2013-02-27

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired