BR112012014299A2 - composto de antivírus heterocíclicos - Google Patents
composto de antivírus heterocíclicosInfo
- Publication number
- BR112012014299A2 BR112012014299A2 BR112012014299A BR112012014299A BR112012014299A2 BR 112012014299 A2 BR112012014299 A2 BR 112012014299A2 BR 112012014299 A BR112012014299 A BR 112012014299A BR 112012014299 A BR112012014299 A BR 112012014299A BR 112012014299 A2 BR112012014299 A2 BR 112012014299A2
- Authority
- BR
- Brazil
- Prior art keywords
- antivirus
- heterocyclic
- compound
- disclosed
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
compostos e antivírus heterocíclicos expõem-se compostos que são dotados da fórmula i em que r^ 1^, r^ 2^, r^ 3^, r^ 4^, r^ 5^, r^ a^, r^ b^, r^ c^, r^ d^ e n são tais como definidos neste contexto os quais são inibidores de polimerase de vírus ns5b de hepatite c. expõem-se igualmente composições e métodos para o tratamento de uma infecção por hcv e inibição de replicação de hcv.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28613609P | 2009-12-14 | 2009-12-14 | |
PCT/EP2010/069442 WO2011073114A1 (en) | 2009-12-14 | 2010-12-13 | Heterocyclic antiviral compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012014299A2 true BR112012014299A2 (pt) | 2016-07-05 |
Family
ID=43446588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012014299A BR112012014299A2 (pt) | 2009-12-14 | 2010-12-13 | composto de antivírus heterocíclicos |
Country Status (12)
Country | Link |
---|---|
US (1) | US20110123490A1 (pt) |
EP (1) | EP2513092A1 (pt) |
JP (1) | JP2013513584A (pt) |
KR (1) | KR20120104343A (pt) |
CN (1) | CN102652134A (pt) |
AR (1) | AR079440A1 (pt) |
BR (1) | BR112012014299A2 (pt) |
CA (1) | CA2780526A1 (pt) |
MX (1) | MX2012006513A (pt) |
RU (1) | RU2012129657A (pt) |
TW (1) | TW201144298A (pt) |
WO (1) | WO2011073114A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8178547B2 (en) * | 2008-12-22 | 2012-05-15 | Roche Palo Alto Llc | Heterocyclic antiviral compounds |
AU2010330048B9 (en) | 2009-12-11 | 2015-02-19 | Autifony Therapeutics Limited | Imidazolidinedione derivatives |
CA2817205C (en) | 2010-12-06 | 2020-04-07 | Autifony Therapeutics Limited | Hydantoin derivatives useful as kv3 inhibitors |
US9193704B2 (en) | 2011-06-07 | 2015-11-24 | Autifony Therapeutics Limited | Hydantoin derivatives as KV3 inhibitors |
ES2576628T3 (es) * | 2011-12-06 | 2016-07-08 | Autifony Therapeutics Limited | Derivados de hidantoína útiles como inhibidores de Kv3 |
BR112014028718A2 (pt) | 2012-05-22 | 2017-06-27 | Autifony Therapeutics Ltd | derivados de hidantoína como inibidores de kv3 |
US9422252B2 (en) | 2012-05-22 | 2016-08-23 | Autifony Therapeutics Limited | Triazoles as Kv3 inhibitors |
CN106065009B (zh) * | 2014-06-28 | 2019-03-01 | 广东东阳光药业有限公司 | 作为丙型肝炎抑制剂的化合物及其在药物中的应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2014147354A (ru) * | 2007-09-17 | 2015-07-10 | Эббви Бахамаз Лтд. | Пиримидины, которые могут быть использованы в качестве противоинфекционных средств, и их применения |
CN102746239B (zh) * | 2007-09-17 | 2016-02-10 | 艾伯维巴哈马有限公司 | 治疗丙型肝炎的尿嘧啶或胸腺嘧啶衍生物 |
CN102448952B (zh) * | 2009-03-25 | 2014-10-29 | Abbvie公司 | 抗病毒化合物和其用途 |
-
2010
- 2010-12-13 CN CN2010800564841A patent/CN102652134A/zh active Pending
- 2010-12-13 EP EP10787145A patent/EP2513092A1/en not_active Withdrawn
- 2010-12-13 AR ARP100104600A patent/AR079440A1/es unknown
- 2010-12-13 MX MX2012006513A patent/MX2012006513A/es unknown
- 2010-12-13 CA CA2780526A patent/CA2780526A1/en not_active Abandoned
- 2010-12-13 TW TW099143545A patent/TW201144298A/zh unknown
- 2010-12-13 BR BR112012014299A patent/BR112012014299A2/pt not_active IP Right Cessation
- 2010-12-13 JP JP2012542574A patent/JP2013513584A/ja active Pending
- 2010-12-13 KR KR1020127018270A patent/KR20120104343A/ko not_active Application Discontinuation
- 2010-12-13 RU RU2012129657/04A patent/RU2012129657A/ru unknown
- 2010-12-13 WO PCT/EP2010/069442 patent/WO2011073114A1/en active Application Filing
- 2010-12-14 US US12/967,657 patent/US20110123490A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
RU2012129657A (ru) | 2014-01-27 |
WO2011073114A1 (en) | 2011-06-23 |
TW201144298A (en) | 2011-12-16 |
MX2012006513A (es) | 2012-07-17 |
JP2013513584A (ja) | 2013-04-22 |
EP2513092A1 (en) | 2012-10-24 |
KR20120104343A (ko) | 2012-09-20 |
AR079440A1 (es) | 2012-01-25 |
CA2780526A1 (en) | 2011-06-23 |
CN102652134A (zh) | 2012-08-29 |
US20110123490A1 (en) | 2011-05-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 4A E 5A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |
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B350 | Update of information on the portal [chapter 15.35 patent gazette] |