BR112012014190B8 - composição farmacêutica para o tratamento da síndrome do olho seco - Google Patents
composição farmacêutica para o tratamento da síndrome do olho secoInfo
- Publication number
- BR112012014190B8 BR112012014190B8 BR112012014190A BR112012014190A BR112012014190B8 BR 112012014190 B8 BR112012014190 B8 BR 112012014190B8 BR 112012014190 A BR112012014190 A BR 112012014190A BR 112012014190 A BR112012014190 A BR 112012014190A BR 112012014190 B8 BR112012014190 B8 BR 112012014190B8
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- pharmaceutical composition
- dry eye
- eye syndrome
- compositions
- Prior art date
Links
- 208000003556 Dry Eye Syndromes Diseases 0.000 title abstract 3
- 206010013774 Dry eye Diseases 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 208000009319 Keratoconjunctivitis Sicca Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000003120 macrolide antibiotic agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BR122017018955-7A BR122017018955B1 (pt) | 2009-12-14 | 2010-12-13 | Composição farmacêutica para o tratamento da síndrome do olho seco |
| BR122020020872-4A BR122020020872B1 (pt) | 2009-12-14 | 2010-12-13 | Composição farmacêutica para o tratamento da síndrome do olho seco |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09015423A EP2335735A1 (en) | 2009-12-14 | 2009-12-14 | Pharmaceutical composition for treatment of dry eye syndrome |
| EP09015423.8 | 2009-12-14 | ||
| PCT/EP2010/069495 WO2011073134A1 (en) | 2009-12-14 | 2010-12-13 | Pharmaceutical composition for treatment of dry eye syndrome |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112012014190A2 BR112012014190A2 (pt) | 2016-05-31 |
| BR112012014190B1 BR112012014190B1 (pt) | 2021-03-02 |
| BR112012014190B8 true BR112012014190B8 (pt) | 2021-05-25 |
Family
ID=41731659
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012014190A BR112012014190B8 (pt) | 2009-12-14 | 2010-12-13 | composição farmacêutica para o tratamento da síndrome do olho seco |
| BR122020020872-4A BR122020020872B1 (pt) | 2009-12-14 | 2010-12-13 | Composição farmacêutica para o tratamento da síndrome do olho seco |
| BR122017018955-7A BR122017018955B1 (pt) | 2009-12-14 | 2010-12-13 | Composição farmacêutica para o tratamento da síndrome do olho seco |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR122020020872-4A BR122020020872B1 (pt) | 2009-12-14 | 2010-12-13 | Composição farmacêutica para o tratamento da síndrome do olho seco |
| BR122017018955-7A BR122017018955B1 (pt) | 2009-12-14 | 2010-12-13 | Composição farmacêutica para o tratamento da síndrome do olho seco |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US8614178B2 (enExample) |
| EP (2) | EP2335735A1 (enExample) |
| JP (5) | JP5663595B2 (enExample) |
| KR (2) | KR101652714B1 (enExample) |
| CN (1) | CN102652022B (enExample) |
| AU (1) | AU2010333039B2 (enExample) |
| BR (3) | BR112012014190B8 (enExample) |
| CA (2) | CA2776860C (enExample) |
| DK (1) | DK2512515T3 (enExample) |
| ES (1) | ES2449308T3 (enExample) |
| IN (1) | IN2012DN03128A (enExample) |
| MX (1) | MX2012006720A (enExample) |
| PL (1) | PL2512515T3 (enExample) |
| PT (1) | PT2512515E (enExample) |
| WO (1) | WO2011073134A1 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010256558B2 (en) | 2009-06-03 | 2013-10-03 | Forsight Labs, Llc | Anterior segment drug delivery |
| US10045996B2 (en) | 2010-03-17 | 2018-08-14 | Novaliq Gmbh | Pharmaceutical composition for treatment of increased intraocular pressure |
| EP2444063A1 (en) | 2010-10-20 | 2012-04-25 | Novaliq GmbH | Liquid pharmaceutical compositions for the delivery of active ingredients |
| EP2462921A1 (en) | 2010-11-11 | 2012-06-13 | Novaliq GmbH | Liquid pharmaceutical compositions for the treatment of a posterior eye disease |
| DK2714008T3 (en) | 2011-05-25 | 2017-03-13 | Novaliq Gmbh | PHARMACEUTICAL COMPOSITION FOR APPLICATION ON NAIL |
| EP2714010B1 (en) | 2011-05-25 | 2017-03-01 | Novaliq GmbH | Topical pharmaceutical composition based on semifluorinated alkanes |
| ES2625538T3 (es) | 2012-01-23 | 2017-07-19 | Novaliq Gmbh | Composiciones de proteínas estabilizadas basadas en alcanos semifluorados |
| CN104619314B (zh) | 2012-09-12 | 2017-09-22 | 诺瓦利克有限责任公司 | 包含半氟化烷烃的混合物的组合物 |
| BR112015005008B1 (pt) | 2012-09-12 | 2022-04-19 | Novaliq Gmbh | Composições de alcano semifluorado |
| EP2708228B1 (en) | 2012-09-12 | 2018-05-16 | Novaliq GmbH | Eye wash compositions |
| EP2730291A1 (en) * | 2012-11-09 | 2014-05-14 | Fluoron Gmbh | Internal Tamponade Composition |
| WO2014117035A1 (en) | 2013-01-24 | 2014-07-31 | Transderm, Inc. | COMPOSITIONS FOR TRANSDERMAL DELIVERY OF mTOR INHIBITORS |
| JP6304475B2 (ja) * | 2013-01-31 | 2018-04-04 | ロート製薬株式会社 | 点眼剤 |
| CN105073112B (zh) | 2013-03-13 | 2017-12-29 | 参天制药株式会社 | 睑板腺功能障碍的治疗剂 |
| CN114028560A (zh) * | 2013-07-23 | 2022-02-11 | 诺瓦利克有限责任公司 | 稳定的抗体组合物 |
| CA2927321A1 (en) * | 2013-10-15 | 2015-04-23 | Forsight Vision5, Inc. | Formulations and methods for increasing or reducing mucus |
| US20200237859A1 (en) | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| US11324800B2 (en) | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| US20160296532A1 (en) | 2015-04-13 | 2016-10-13 | Forsight Vision5, Inc. | Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent |
| US11013403B2 (en) * | 2015-09-29 | 2021-05-25 | The Regents Of The University Of California | Methods of diagnosing diseases of mucosal surfaces |
| CN113662929A (zh) * | 2015-09-30 | 2021-11-19 | 诺瓦利克有限责任公司 | 用于眼部给药的半氟化化合物 |
| CN108348777B (zh) | 2015-09-30 | 2020-04-28 | 诺瓦利克有限责任公司 | 半氟化化合物和其组合物 |
| USRE50060E1 (en) | 2016-06-23 | 2024-07-30 | Novaliq Gmbh | Topical administration method |
| ES2969758T3 (es) | 2016-09-22 | 2024-05-22 | Novaliq Gmbh | Composiciones farmacéuticas para usar en la terapia de la blefaritis |
| KR20190057338A (ko) * | 2016-09-23 | 2019-05-28 | 노바리크 게엠베하 | 시클로스포린을 포함하는 안과 조성물 |
| BR112019006194A2 (pt) * | 2016-09-28 | 2019-06-18 | Novaliq Gmbh | composições que compreendem um ligante de ligação ao receptor de canabinóides |
| WO2018114557A1 (en) * | 2016-12-22 | 2018-06-28 | Novaliq Gmbh | Compositions comprising tacrolimus for the treatment of intraocular inflammatory eye diseases |
| ES2819005T3 (es) * | 2016-12-23 | 2021-04-14 | Novaliq Gmbh | Composición oftálmica para el tratamiento de la enfermedad del ojo seco |
| AU2018205253B2 (en) | 2017-01-06 | 2022-01-13 | Palvella Therapeutics, Inc. | Anhydrous compositions of mTOR inhibitors and methods of use |
| EP3612228B1 (en) * | 2017-04-21 | 2023-08-23 | Dermaliq Therapeutics, Inc. | Iodine compositions |
| EP3619186B1 (en) | 2017-05-05 | 2021-02-17 | Novaliq GmbH | Process for the production of semifluorinated alkanes |
| US11278503B2 (en) | 2017-05-12 | 2022-03-22 | Novaliq Gmbh | Pharmaceutical compositions comprising semifluorinated alkanes for the treatment of contact lense-related conditions |
| MX2020003534A (es) | 2017-09-27 | 2020-07-29 | Novaliq Gmbh | Composiciones oftalmicas que comprenden latanoprost para usarse en el tratamiento de las enfermedades oculares. |
| CN111182893A (zh) | 2017-10-04 | 2020-05-19 | 诺瓦利克有限责任公司 | 包含f6h8的眼用组合物 |
| AU2019228119A1 (en) | 2018-03-02 | 2020-09-10 | Novaliq Gmbh | Pharmaceutical compositions comprising nebivolol |
| IL276888B2 (en) | 2018-03-28 | 2024-12-01 | Novaliq Gmbh | Pharmaceutical composition comprising timolol |
| EP3784246A1 (en) | 2018-04-27 | 2021-03-03 | Novaliq GmbH | Ophthalmic compositions comprising tafluprost for the treatment of glaucoma |
| EP3817743A4 (en) | 2018-07-02 | 2022-07-06 | Palvella Therapeutics, Inc. | ANHYDROUS COMPOSITIONS OF MTOR INHIBITORS AND METHODS OF USE |
| KR20210080388A (ko) | 2018-09-22 | 2021-06-30 | 노바리크 게엠베하 | 안구 표면 손상 및 건조 증상 치료를 위한 안약 조성물 |
| EP3856124A1 (en) | 2018-09-27 | 2021-08-04 | Novaliq GmbH | Lipid barrier repair |
| CN112823020A (zh) | 2018-10-12 | 2021-05-18 | 诺瓦利克有限责任公司 | 用于治疗干眼病的眼用组合物 |
| US20220008397A1 (en) * | 2019-01-21 | 2022-01-13 | Novaliq Gmbh | Pharmaceutical composition for the treatment of ocular neovascularisation |
| EP3923907B1 (en) | 2019-02-13 | 2024-09-25 | Novaliq GmbH | Compositions and methods for the treatment of ocular neovascularization |
| AU2020281641B2 (en) | 2019-05-24 | 2025-09-11 | Novaliq Gmbh | Ophthalmic composition for the treatment of ocular allergy |
| AU2020340561B2 (en) | 2019-09-06 | 2026-01-22 | Novaliq Gmbh | Ophthalmic composition for the treatment of uveitis |
| WO2021048803A1 (en) | 2019-09-13 | 2021-03-18 | Minas Coroneo | Eye drop dispenser |
| WO2021191273A1 (en) | 2020-03-24 | 2021-09-30 | Hovione Scientia Limited | Compositions for use in treating meibomian gland dysfunction |
| US11191751B1 (en) * | 2020-10-08 | 2021-12-07 | Ads Therapeutics Llc | Topical ophthalmological atropine free base compositions |
| WO2024170514A1 (en) * | 2023-02-13 | 2024-08-22 | Novaliq Gmbh | Ophthalmic composition for ocular surgery preparation in patients with ocular surface disease |
| AU2023270196B2 (en) * | 2023-11-20 | 2025-06-26 | Dyer, Gordon Wayne DR | Method of Arthropod Egress |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4839342A (en) | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
| KR920003601B1 (ko) | 1987-09-03 | 1992-05-04 | 유니버시티 어브 죠지아 리서취 화운데이션 인코포레이티드 | 점안 싸이클로스포린(cyclosporin)의 조성물 |
| US5874481A (en) * | 1995-06-07 | 1999-02-23 | Alliance Pharmaceutical Corp. | Fluorochemical solutions for the delivery of lipophilic pharmaceutical agents |
| DE19536504C2 (de) * | 1995-09-29 | 1999-09-23 | H Meinert | Verwendung fluorierter Alkane |
| DE19861012A1 (de) * | 1998-03-18 | 1999-09-30 | Pharm Pur Gmbh | Behandlungsmittel für die Ophthalmologie |
| CN1190194C (zh) * | 1999-04-30 | 2005-02-23 | 苏坎波公司 | 用于治疗干眼的大环内酯化合物的应用 |
| DE19938668B4 (de) * | 1999-08-14 | 2006-01-26 | Bausch & Lomb Inc. | Tränenersatzmittel |
| US20030018044A1 (en) * | 2000-02-18 | 2003-01-23 | Peyman Gholam A. | Treatment of ocular disease |
| ES2387619T3 (es) * | 2004-04-19 | 2012-09-27 | Centre National De La Recherche Scientifique (Cnrs) | Suplementos de tensioactivos pulmonares |
| JP2008501806A (ja) * | 2004-06-08 | 2008-01-24 | オキュラリス ファーマ， インコーポレイテッド | 疎水性眼用組成物および使用方法 |
| DE102007055046A1 (de) * | 2007-11-19 | 2009-05-28 | Fluoron Gmbh | Infusionslösung |
| EP2110126B9 (de) | 2008-04-18 | 2012-09-19 | Novaliq GmbH | Inhalative und instillative Verwendung von semifluorierten Alkanen als Wirkstoffträger im intrapulmonalen Bereich |
-
2009
- 2009-12-14 EP EP09015423A patent/EP2335735A1/en not_active Withdrawn
-
2010
- 2010-12-13 PL PL10790775T patent/PL2512515T3/pl unknown
- 2010-12-13 CA CA2776860A patent/CA2776860C/en active Active
- 2010-12-13 BR BR112012014190A patent/BR112012014190B8/pt active IP Right Grant
- 2010-12-13 DK DK10790775.0T patent/DK2512515T3/en active
- 2010-12-13 BR BR122020020872-4A patent/BR122020020872B1/pt active IP Right Grant
- 2010-12-13 WO PCT/EP2010/069495 patent/WO2011073134A1/en not_active Ceased
- 2010-12-13 ES ES10790775.0T patent/ES2449308T3/es active Active
- 2010-12-13 JP JP2012542577A patent/JP5663595B2/ja active Active
- 2010-12-13 AU AU2010333039A patent/AU2010333039B2/en active Active
- 2010-12-13 BR BR122017018955-7A patent/BR122017018955B1/pt active IP Right Grant
- 2010-12-13 KR KR1020127018066A patent/KR101652714B1/ko active Active
- 2010-12-13 IN IN3128DEN2012 patent/IN2012DN03128A/en unknown
- 2010-12-13 EP EP10790775.0A patent/EP2512515B1/en active Active
- 2010-12-13 CN CN201080055507.7A patent/CN102652022B/zh active Active
- 2010-12-13 US US13/513,886 patent/US8614178B2/en active Active
- 2010-12-13 MX MX2012006720A patent/MX2012006720A/es active IP Right Grant
- 2010-12-13 PT PT107907750T patent/PT2512515E/pt unknown
- 2010-12-13 KR KR1020167023214A patent/KR101722039B1/ko active Active
- 2010-12-13 CA CA2941956A patent/CA2941956C/en active Active
-
2014
- 2014-10-01 JP JP2014203406A patent/JP6096731B2/ja active Active
-
2016
- 2016-12-22 JP JP2016248533A patent/JP6397472B2/ja active Active
-
2018
- 2018-08-31 JP JP2018163569A patent/JP2019006803A/ja active Pending
- 2018-12-28 JP JP2018248700A patent/JP6731039B2/ja active Active
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Legal Events
| Date | Code | Title | Description |
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