BR112012011767A2 - cadeias de magnetossomos bacterianas, método e kit - Google Patents

cadeias de magnetossomos bacterianas, método e kit

Info

Publication number
BR112012011767A2
BR112012011767A2 BR112012011767A BR112012011767A BR112012011767A2 BR 112012011767 A2 BR112012011767 A2 BR 112012011767A2 BR 112012011767 A BR112012011767 A BR 112012011767A BR 112012011767 A BR112012011767 A BR 112012011767A BR 112012011767 A2 BR112012011767 A2 BR 112012011767A2
Authority
BR
Brazil
Prior art keywords
kit
magnetosome chains
bacterial magnetosome
bacterial
chains
Prior art date
Application number
BR112012011767A
Other languages
English (en)
Inventor
Alphandery Edouard
Chebbi Iméne
Faure Stéphanie
Original Assignee
Nanobacterie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanobacterie filed Critical Nanobacterie
Publication of BR112012011767A2 publication Critical patent/BR112012011767A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/40—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia
    • A61N1/406—Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia using implantable thermoseeds or injected particles for localized hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BR112012011767A 2009-11-18 2010-11-18 cadeias de magnetossomos bacterianas, método e kit BR112012011767A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26226009P 2009-11-18 2009-11-18
US37138510P 2010-08-06 2010-08-06
PCT/EP2010/067765 WO2011061259A1 (en) 2009-11-18 2010-11-18 Treatment of cancer or tumor induced by the release of heat generated by various chains of magnetosomes extracted from magnetotactic bacteria and submitted to an alternative magnetic field

Publications (1)

Publication Number Publication Date
BR112012011767A2 true BR112012011767A2 (pt) 2018-03-27

Family

ID=43608300

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012011767A BR112012011767A2 (pt) 2009-11-18 2010-11-18 cadeias de magnetossomos bacterianas, método e kit

Country Status (11)

Country Link
US (3) US10238886B2 (pt)
EP (1) EP2370085B1 (pt)
JP (3) JP6202358B2 (pt)
CN (1) CN102811726B (pt)
AU (1) AU2010320918B2 (pt)
BR (1) BR112012011767A2 (pt)
CA (1) CA2780851C (pt)
ES (1) ES2539588T3 (pt)
IL (1) IL219745A (pt)
RU (1) RU2593331C2 (pt)
WO (1) WO2011061259A1 (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6202358B2 (ja) * 2009-11-18 2017-09-27 ナノバクテリー 走磁性細菌から抽出され交流磁場に供されたマグネトソームの様々な鎖により生成される熱の放出により誘導される、癌または腫瘍の治療
EP2575896A2 (en) * 2010-05-26 2013-04-10 Erik Reimhult Magnetically responsive membrane structures
FR2974815B1 (fr) * 2011-05-06 2014-01-10 Univ Paris Curie Utilisation d'au moins un agent chelatant introduit dans le milieu de culture de bacteries magnetotactiques pour stimuler la croissance de ces bacteries
US8828681B2 (en) 2012-01-13 2014-09-09 Bell Biosystems, Inc. Host cells with artificial endosymbionts
US9023612B2 (en) 2012-01-13 2015-05-05 Bell Biosystems, Inc. Eukaryotic cells with artificial endosymbionts for multimodal detection
US8956873B2 (en) 2012-01-13 2015-02-17 Bell Biosystems, Inc. Host cells with artificial endosymbionts
US10076579B2 (en) 2012-01-13 2018-09-18 Bell Biosystems, Inc. Host cells with artificial endosymbionts
WO2013170379A1 (en) * 2012-05-13 2013-11-21 Corporation De L'ecole Polytechnique De Montreal Drug delivery across the blood-brain barrier using magnetically heatable entities
EP2666456A1 (en) * 2012-05-21 2013-11-27 Natura Bisse International, S.A. Cometic compositions comprising magnetosomes and uses thereof
WO2014085751A1 (en) * 2012-11-29 2014-06-05 Micromed Scientia, Inc. Shielding of magnetic field as a medical therapy
WO2014145785A1 (en) 2013-03-15 2014-09-18 Bell Biosystems, Llc Host cells with artificial endosymbionts
EP2818056A1 (en) 2013-06-25 2014-12-31 Biosearch S.A. Probiotic bacteria comprising metals, metal nanoparticles and uses thereof
SG11201601488VA (en) 2013-09-03 2016-03-30 Bell Biosystems Inc Host cell modification with artificial endosymbionts
CN104211753B (zh) * 2014-09-12 2018-08-21 江南大学 一种细菌纳米磁小体-糖鞘脂复合物及其制备方法与应用
FR3037581B1 (fr) 2015-06-17 2022-05-13 Nanobacterie Preparation apyrogene contenant des nanoparticules synthetisees par des bacteries magnetotactiques pour des applications medicales ou cosmetiques
GB2556010A (en) 2015-08-20 2018-05-16 E Sandstrom Robert Method of attacking target cells
FR3042874A1 (fr) * 2015-10-21 2017-04-28 Nanobacterie Particule comprenant au moins une particule d'oxyde de fer ferrimagnetique associee a au moins un compose pour une utilisation medicale ou cosmetique
EP3371205A1 (en) * 2015-11-06 2018-09-12 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Modified magnetotactic bacteria expressing a metallophore specific for cobalt and/or nickel
EP3311838A1 (en) * 2016-10-21 2018-04-25 Nanobacterie Magnetic nanoparticles associated to immunogenic entities for destroying pathological cells in an individual
EP3311839A1 (en) * 2016-10-21 2018-04-25 Nanobacterie Magnetic nanoparticles for destroying pathological cells in an individual
EP3363496A1 (en) * 2017-02-16 2018-08-22 Nanobacterie Magnetic field oscillating at several frequencies for improving efficacy and/or reducing toxicity of magnetic hyperthermia
IL267760B2 (en) * 2017-11-30 2023-11-01 Nanobacterie Nanoparticles are continuously exposed to low intensity acoustic waves for medical or cosmetic applications
EP3492103A1 (en) * 2017-11-30 2019-06-05 Nanobacterie Magnetosomes for use in an acoustic wave medical treatment
EP3492102A1 (en) * 2017-11-30 2019-06-05 Nanobacterie Nanoparticles exposed sequentially to low intensity acoustic waves for medical treatment
US11571393B2 (en) * 2018-05-16 2023-02-07 Nanobacterie Magnetic nanoparticles sequentially irradiated by laser radiation for medical or chemical or biological or cosmetic applications
EP3633042A1 (en) * 2018-10-02 2020-04-08 Nanobacterie Method for removing impurities from nanoparticles
FR3095340B1 (fr) 2019-04-25 2023-06-09 Nanobacterie Procede d'augmentation de la liberation de composes medicaux de nanoparticules apres une etape d’altération et une etape de perturbation physico-chimique
CN110029050A (zh) * 2019-05-28 2019-07-19 甘肃中医药大学 一种控制趋磁细菌培养过程氧浓度的装置及培养方法
WO2021112389A1 (ko) * 2019-12-02 2021-06-10 주식회사 엘지화학 자성체, 이를 포함하는 경화성 조성물 및 상기 자성체의 제조 방법
WO2023240342A1 (en) * 2022-06-14 2023-12-21 Starpax Biopharma Inc. System for focused targeting of magneto-aerotactic-responsive bacteria and method of use thereof
FR3142904A1 (fr) * 2022-12-07 2024-06-14 Nanobacterie Nanoparticules disposées en chaînes dans une composition isotonique apres reconstitution
EP4385499A1 (en) * 2022-11-15 2024-06-19 Nanobacterie A method to enable nanoparticles stored with a specific type of assembly to maintain this type of assembly upon reconstitution

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4385119A (en) * 1980-03-27 1983-05-24 Biomagnetech Corp. Magnetic bacteria and products derived therefrom
US4394451A (en) * 1980-10-30 1983-07-19 Biomagnetech Corp. Culture medium and conditions for growth of magnetic bacteria
WO1998040049A2 (de) * 1997-03-07 1998-09-17 Max-Delbrück-Centrum für Molekulare Medizin Spezifische magnetosomen, verfahren zu ihrer herstellung und ihre verwendung
DE19716732C2 (de) 1997-03-07 1999-03-25 Max Delbrueck Centrum Spezifische Magnetosomen, Verfahren zu ihrer Herstellung und ihre Verwendung
EP1278512A2 (en) * 2000-05-03 2003-01-29 MBT Munich Biotechnology AG Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites
US7074175B2 (en) 2001-07-25 2006-07-11 Erik Schroeder Handy Thermotherapy via targeted delivery of nanoscale magnetic particles
GB0214209D0 (en) * 2002-06-19 2002-07-31 Univ Keele Method
AU2003900335A0 (en) 2003-01-22 2003-02-13 Sirtex Medical Limited Microparticles for selectively targeted hyperthermia
US20050090732A1 (en) * 2003-10-28 2005-04-28 Triton Biosystems, Inc. Therapy via targeted delivery of nanoscale particles
US20060167313A1 (en) 2004-12-28 2006-07-27 Council Of Scientific And Industrial Research Process for preparing encapsulated metalloporphyrin catalyst and process for oxidation of alcohols
DE102005016873A1 (de) 2005-04-12 2006-10-19 Magforce Nanotechnologies Ag Nanopartikel-Wirstoff-Konjugate
AU2007257180A1 (en) 2006-06-08 2007-12-13 Multi-Magnetics Incorporated Magnetosome gene expression in eukaryotic cells
JP6202358B2 (ja) * 2009-11-18 2017-09-27 ナノバクテリー 走磁性細菌から抽出され交流磁場に供されたマグネトソームの様々な鎖により生成される熱の放出により誘導される、癌または腫瘍の治療

Also Published As

Publication number Publication date
JP2018162317A (ja) 2018-10-18
RU2012122639A (ru) 2013-12-27
AU2010320918B2 (en) 2016-02-11
WO2011061259A1 (en) 2011-05-26
RU2593331C2 (ru) 2016-08-10
JP2013511491A (ja) 2013-04-04
JP2016155821A (ja) 2016-09-01
EP2370085B1 (en) 2015-04-15
IL219745A (en) 2016-04-21
CN102811726B (zh) 2015-03-18
US20120302819A1 (en) 2012-11-29
US10252073B2 (en) 2019-04-09
IL219745A0 (en) 2012-07-31
AU2010320918A1 (en) 2012-06-07
US10974059B2 (en) 2021-04-13
EP2370085A1 (en) 2011-10-05
US20190201704A1 (en) 2019-07-04
CN102811726A (zh) 2012-12-05
ES2539588T3 (es) 2015-07-02
CA2780851A1 (en) 2011-05-26
US10238886B2 (en) 2019-03-26
JP6469603B2 (ja) 2019-02-13
CA2780851C (en) 2016-12-13
US20170157253A1 (en) 2017-06-08
JP6202358B2 (ja) 2017-09-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]