BR112012008065B8 - Composição em pó ou granulada compreendendo um copolímero, um ácido dicarboxílico e um ácido monocarboxílico graxo, e seu processo de preparação - Google Patents

Composição em pó ou granulada compreendendo um copolímero, um ácido dicarboxílico e um ácido monocarboxílico graxo, e seu processo de preparação

Info

Publication number
BR112012008065B8
BR112012008065B8 BR112012008065A BR112012008065A BR112012008065B8 BR 112012008065 B8 BR112012008065 B8 BR 112012008065B8 BR 112012008065 A BR112012008065 A BR 112012008065A BR 112012008065 A BR112012008065 A BR 112012008065A BR 112012008065 B8 BR112012008065 B8 BR 112012008065B8
Authority
BR
Brazil
Prior art keywords
copolymer
acid
powder
granulated composition
dicarboxylic acid
Prior art date
Application number
BR112012008065A
Other languages
English (en)
Other versions
BR112012008065A8 (pt
BR112012008065A2 (pt
BR112012008065B1 (pt
Inventor
Roth Erna
Alexowsky Rüdiger
Petereit Hans-Ulrich
Meier Christian
Original Assignee
Evonik Roehm Gmbh
Roehm Gmbh
Evonik Degussa Gmbh
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Roehm Gmbh, Roehm Gmbh, Evonik Degussa Gmbh, Evonik Operations Gmbh filed Critical Evonik Roehm Gmbh
Publication of BR112012008065A2 publication Critical patent/BR112012008065A2/pt
Publication of BR112012008065A8 publication Critical patent/BR112012008065A8/pt
Publication of BR112012008065B1 publication Critical patent/BR112012008065B1/pt
Publication of BR112012008065B8 publication Critical patent/BR112012008065B8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/04Oxygen-containing compounds
    • C08K5/09Carboxylic acids; Metal salts thereof; Anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L33/00Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • C08L33/04Homopolymers or copolymers of esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F20/00Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride, ester, amide, imide or nitrile thereof
    • C08F20/02Monocarboxylic acids having less than ten carbon atoms, Derivatives thereof
    • C08F20/10Esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00Processes of treating or compounding macromolecular substances
    • C08J3/12Powdering or granulating
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/04Oxygen-containing compounds
    • C08K5/09Carboxylic acids; Metal salts thereof; Anhydrides thereof
    • C08K5/092Polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Paints Or Removers (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

COMPOSIÇÃO EM PÓ OU GRANULADA COMPREENDENDO UM COPOLÍMERO, UM ÁCIDO DICARBOXÍLICO E UM ÁCIDO MONOCARBOXÍLICO GRAXO. A presente invenção refere-se a uma composição em pó ou granulada que compreende pelo menos por 30% por peso de uma mistura dos componentes (a), (b) e (c) com (a) um copolímero composto de unidades polimerizadas de C 1- a C 4-alquil ésteres de ácido acrílico ou metacrílico e de monômeros de alquil(met)acrilato com um grupo amino terciário no radical alquila e (b) 0,5 a 10% por peso com base em (a) de um ácido dicarboxílico tendo 3 a 10 átomos de carbono e (c) 5 a 20% por peso com base em (a) de um ácido monocarboxílico graxo tendo 8 a 18 átomos de carbono.
BR112012008065A 2009-07-30 2009-07-30 Composição em pó ou granulada compreendendo um copolímero, um ácido dicarboxílico e um ácido monocarboxílico graxo, e seu processo de preparação BR112012008065B8 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2009/059850 WO2011012161A1 (en) 2009-07-30 2009-07-30 Powdery or granulated composition comprising a copolymer, a dicarboxylic acid and a fatty monocarboxylic acid

Publications (4)

Publication Number Publication Date
BR112012008065A2 BR112012008065A2 (pt) 2016-03-01
BR112012008065A8 BR112012008065A8 (pt) 2016-10-11
BR112012008065B1 BR112012008065B1 (pt) 2019-09-03
BR112012008065B8 true BR112012008065B8 (pt) 2022-07-05

Family

ID=41416545

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012008065A BR112012008065B8 (pt) 2009-07-30 2009-07-30 Composição em pó ou granulada compreendendo um copolímero, um ácido dicarboxílico e um ácido monocarboxílico graxo, e seu processo de preparação

Country Status (15)

Country Link
US (1) US10113050B2 (pt)
EP (1) EP2459634B1 (pt)
JP (1) JP5335142B2 (pt)
KR (1) KR101647869B1 (pt)
CN (1) CN102471523A (pt)
BR (1) BR112012008065B8 (pt)
CA (1) CA2769438C (pt)
ES (1) ES2626244T3 (pt)
HK (1) HK1217505A1 (pt)
HU (1) HUE033556T2 (pt)
IL (1) IL216269A (pt)
MX (1) MX340057B (pt)
PL (1) PL2459634T3 (pt)
SI (1) SI2459634T1 (pt)
WO (1) WO2011012161A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057676A1 (en) 2009-11-16 2011-05-19 Evonik Röhm Gmbh A process for converting a solid (meth)acrylate copolymer into a dispersed form by means of a dispersing agent
EP2636403A1 (de) * 2012-03-09 2013-09-11 Basf Se Herstellung von pharmazeutischen protektiven Überzügen mit guter Resistenz im neutralen Milieu
WO2014048507A1 (en) 2012-09-28 2014-04-03 Evonik Industries Ag Process for preparing aqueous dispersions
EP2922907A1 (en) 2012-11-22 2015-09-30 Evonik Röhm GmbH Process for preparing a granulated product from a powder composition
MX2016014405A (es) * 2014-05-05 2017-01-20 Boehringer Ingelheim Int Granulado de disolucion rapida.

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5112898A (en) 1989-06-06 1992-05-12 Ferro Corporation High impact polystyrene containing low molecular weight brominated polystyrene
JP3454517B2 (ja) * 1991-04-25 2003-10-06 京都薬品工業株式会社 矯味経口剤
DE19845358A1 (de) 1998-10-02 2000-04-06 Roehm Gmbh Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe
US7008640B2 (en) 2000-07-17 2006-03-07 Yamanouchi Pharmaceutical Co., Ltd. Pharmaceutical composition for oral use with improved absorption
JP4057418B2 (ja) 2000-11-07 2008-03-05 久光製薬株式会社 経皮吸収型製剤
DE10061718A1 (de) * 2000-12-12 2002-06-13 Creavis Tech & Innovation Gmbh Bindermittel aus (Meth)acrylatpolymer-Kompositionen mit einstellbaren elektrischen und thermischen Eigenschaften
JP2004517157A (ja) * 2001-01-29 2004-06-10 レーム ゲゼルシヤフト ミツト ベシユレンクテル ハフツング ウント コンパニー コマンディートゲゼルシャフト 薬学的適用のための貯蔵安定性接着および結合剤
SK288049B6 (sk) 2001-02-27 2013-03-01 Evonik Rohm Gmbh Coating and binding agent, its use for production of cover oral or dermal pharmaceutical dosage forms, process for its production and dosage form containing same
ITMI20012827A1 (it) 2001-12-28 2003-06-28 Fidia Farmaceutici Formulazioni adesive transdermiche di diclofenac sodico
DE10200578A1 (de) * 2002-01-09 2003-07-10 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme
CN1204895C (zh) 2002-12-06 2005-06-08 重庆华邦制药股份有限公司 依托泊甙肠溶缓(控)释固体分散制剂及其制备方法
DE10260919A1 (de) * 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug
DE10304403A1 (de) * 2003-01-28 2004-08-05 Röhm GmbH & Co. KG Verfahren zur Herstellung einer oralen Arzneiform mit unmittelbarem Zerfall und Wirkstofffreisetzung
WO2011057676A1 (en) 2009-11-16 2011-05-19 Evonik Röhm Gmbh A process for converting a solid (meth)acrylate copolymer into a dispersed form by means of a dispersing agent

Also Published As

Publication number Publication date
US10113050B2 (en) 2018-10-30
CN102471523A (zh) 2012-05-23
BR112012008065A8 (pt) 2016-10-11
US20120071565A1 (en) 2012-03-22
HUE033556T2 (hu) 2017-12-28
SI2459634T1 (sl) 2017-07-31
IL216269A0 (en) 2012-01-31
EP2459634A1 (en) 2012-06-06
CA2769438C (en) 2017-01-03
BR112012008065A2 (pt) 2016-03-01
MX340057B (es) 2016-06-22
EP2459634B1 (en) 2017-03-29
BR112012008065B1 (pt) 2019-09-03
JP2013500360A (ja) 2013-01-07
JP5335142B2 (ja) 2013-11-06
CA2769438A1 (en) 2011-02-03
HK1217505A1 (zh) 2017-01-13
ES2626244T3 (es) 2017-07-24
WO2011012161A1 (en) 2011-02-03
MX2012001176A (es) 2012-03-14
KR101647869B1 (ko) 2016-08-11
IL216269A (en) 2016-05-31
PL2459634T3 (pl) 2017-09-29
KR20120047241A (ko) 2012-05-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS. (CO) 10 (DEZ) ANOS CONTADOS A PARTIR DE 03/09/2019, OBSERVADAS AS CONDICOES LEGAIS

B25D Requested change of name of applicant approved

Owner name: ROEHM GMBH (DE)

B25G Requested change of headquarter approved

Owner name: ROEHM GMBH (DE)

B25A Requested transfer of rights approved

Owner name: EVONIK DEGUSSA GMBH (DE)

B25D Requested change of name of applicant approved

Owner name: EVONIK OPERATIONS GMBH (DE)