BR112012006831A2 - corpo plano na forma de um cartão com chip para análise bioquímica e método para o uso do mesmo - Google Patents

corpo plano na forma de um cartão com chip para análise bioquímica e método para o uso do mesmo

Info

Publication number
BR112012006831A2
BR112012006831A2 BR112012006831A BR112012006831A BR112012006831A2 BR 112012006831 A2 BR112012006831 A2 BR 112012006831A2 BR 112012006831 A BR112012006831 A BR 112012006831A BR 112012006831 A BR112012006831 A BR 112012006831A BR 112012006831 A2 BR112012006831 A2 BR 112012006831A2
Authority
BR
Brazil
Prior art keywords
flat body
biochemical analysis
chip card
microfluidic device
flat
Prior art date
Application number
BR112012006831A
Other languages
English (en)
Other versions
BR112012006831A8 (pt
BR112012006831B1 (pt
Inventor
Jörn Ueberfeld
Peter Paulicka
Walter Gumbrecht
Original Assignee
Siemens Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Ag filed Critical Siemens Ag
Publication of BR112012006831A2 publication Critical patent/BR112012006831A2/pt
Publication of BR112012006831A8 publication Critical patent/BR112012006831A8/pt
Publication of BR112012006831B1 publication Critical patent/BR112012006831B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0663—Whole sensors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0672—Integrated piercing tool
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0883—Serpentine channels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

corpo plano na forma de um cartão com chip para análise bioquímica e método para uso do mesmo. a presente invenção refere-se a um corpo plano (1) na forma de um cartão com chip para análise bioquímica de substâncias que compreende pelo menos dois dispositivos microfluídos (3,4) e pelo menos um chip com sensor (2). pelo menos um chip com sensor (2) estando em contato direto com pelo menos um primeiro dispositivo microfluídico (3). um segundo dispositivo microfluídico (4) na forma de uma pipeta que é integral com o corpo palno (1) ou conectado ao mesmo. um método para usar o corpo plano (1) compreendo o aancoramneto de um ''e-cup'' (5) por meio de um dispositivo de fixação (6a, 6b) do corpo (1) no corpo plano (1) e para trocar fluido entre o ''e-cup'' (5) e o corpo álno (1) por meio do segundo dispositivo microfluído (4).
BR112012006831A 2009-09-28 2010-09-27 corpo plano na forma de um cartão com chip para análise bioquímica BR112012006831B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009043226A DE102009043226B4 (de) 2009-09-28 2009-09-28 Flachkörper nach Art einer Chip-Karte zur biochemischen Analyse und Verfahren zu dessen Verwendung
PCT/EP2010/064258 WO2011036289A1 (de) 2009-09-28 2010-09-27 Flachkörper nach art einer chip-karte zur biochemischen analyse und verfahren zu dessen verwendung

Publications (3)

Publication Number Publication Date
BR112012006831A2 true BR112012006831A2 (pt) 2016-06-07
BR112012006831A8 BR112012006831A8 (pt) 2017-12-05
BR112012006831B1 BR112012006831B1 (pt) 2020-02-04

Family

ID=43302368

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012006831A BR112012006831B1 (pt) 2009-09-28 2010-09-27 corpo plano na forma de um cartão com chip para análise bioquímica

Country Status (7)

Country Link
US (1) US9415390B2 (pt)
EP (1) EP2482982B1 (pt)
JP (1) JP5430766B2 (pt)
CN (1) CN102548659B (pt)
BR (1) BR112012006831B1 (pt)
DE (1) DE102009043226B4 (pt)
WO (1) WO2011036289A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009043226B4 (de) 2009-09-28 2012-09-27 Siemens Aktiengesellschaft Flachkörper nach Art einer Chip-Karte zur biochemischen Analyse und Verfahren zu dessen Verwendung
EP2514528A1 (en) * 2011-04-19 2012-10-24 Cellix Limited Device and method for assessing the status of cells in a biological fluid
WO2013082316A1 (en) * 2011-11-29 2013-06-06 Caliper Life Sciences, Inc. Systems and methods for sampling of amplification products
US9689029B2 (en) 2011-12-02 2017-06-27 Caliper Life Sciences, Inc. Systems and methods for sampling of amplification products
US10241120B2 (en) * 2011-12-06 2019-03-26 Universite Libre De Bruxelles Method and device for assaying an antigen present on erythrocytes or an antibody binding to an antigen present on erythrocytes
CN104178413B (zh) * 2014-07-04 2016-05-25 宁波美晶医疗技术有限公司 一种稀有细胞分离仪的塑封盒包装结构
CN106501499B (zh) 2015-09-07 2019-12-17 埃克西亚斯医药有限公司 可移动测量单元

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747666A (en) * 1997-03-26 1998-05-05 Willis; John P. Point-of-care analyzer module
US5804437A (en) 1997-08-19 1998-09-08 Biomerieux Vitek, Inc. Locking structure for securing a fluid transfer tube
DE19846466A1 (de) * 1998-10-08 2000-04-27 Ghs Gesundheits Service Ag Analyseverfahren zur simultanen Bestimmung von Parametern aus unterschiedlichen Medien
DE19947495C2 (de) 1999-10-01 2003-05-28 Agilent Technologies Inc Mikrofluidischer Mikrochip
CN1117284C (zh) 1999-10-27 2003-08-06 陆祖宏 微流体生物芯片检测分析板及其应用方法
EP1269140A4 (en) * 2000-03-28 2003-05-02 Caliper Techn Corp METHOD FOR REDUCING FLUID TRANSFER IN MICROFLUIDIC DEVICES
DE10111458B4 (de) 2001-03-09 2008-09-11 Siemens Ag Analyseeinrichtung
US6913933B2 (en) * 2001-12-03 2005-07-05 Ortho-Clinical Diagnostics, Inc. Fluid dispensing algorithm for a variable speed pump driven metering system
US7524464B2 (en) * 2003-09-26 2009-04-28 Ahn Chong H Smart disposable plastic lab-on-a-chip for point-of-care testing
DE102005049976A1 (de) 2004-10-15 2006-04-20 Siemens Ag Anordnung zur integrierten und automatisierten DNA- oder Protein-Analyse in einer einmal verwendbaren Cartridge, Herstellungsverfahren für eine solche Cartridge und Betriebsverfahren der DNA- oder Protein-Analyse unter Verwendung einer solchen Cartridge
US20060165558A1 (en) * 2004-12-21 2006-07-27 Thomas Witty Cartridge for diagnostic assays
US8206650B2 (en) * 2005-04-12 2012-06-26 Chromedx Inc. Joint-diagnostic spectroscopic and biosensor meter
US20090140170A1 (en) 2005-08-11 2009-06-04 Eksigent Technologies, Llc Microfluidic systems, devices and methods for reducing background autofluorescence and the effects thereof
WO2007075919A2 (en) * 2005-12-22 2007-07-05 Honeywell International Inc. Portable sample analyzer system
WO2008002483A2 (en) * 2006-06-23 2008-01-03 Mcneely Michael R Reagent preparation and valving design for liquid testing
US8163535B2 (en) 2006-06-26 2012-04-24 Blood Cell Storage, Inc. Devices and processes for nucleic acid extraction
WO2008001796A1 (fr) 2006-06-30 2008-01-03 Panasonic Corporation Panneau d'analyse et analyseur utilisant ce panneau
JP2008175608A (ja) 2007-01-17 2008-07-31 Yokogawa Electric Corp 化学反応用カートリッジ及びその使用方法
US20090186344A1 (en) * 2008-01-23 2009-07-23 Caliper Life Sciences, Inc. Devices and methods for detecting and quantitating nucleic acids using size separation of amplicons
GB0805296D0 (en) 2008-03-20 2008-04-30 Iti Scotland Ltd Uses of reagents in sample collection and cartridge systems
DE102009043226B4 (de) 2009-09-28 2012-09-27 Siemens Aktiengesellschaft Flachkörper nach Art einer Chip-Karte zur biochemischen Analyse und Verfahren zu dessen Verwendung

Also Published As

Publication number Publication date
EP2482982A1 (de) 2012-08-08
WO2011036289A1 (de) 2011-03-31
DE102009043226B4 (de) 2012-09-27
CN102548659B (zh) 2016-12-07
JP2013506123A (ja) 2013-02-21
EP2482982B1 (de) 2017-08-16
DE102009043226A1 (de) 2011-03-31
BR112012006831A8 (pt) 2017-12-05
US9415390B2 (en) 2016-08-16
US20120184043A1 (en) 2012-07-19
CN102548659A (zh) 2012-07-04
BR112012006831B1 (pt) 2020-02-04
JP5430766B2 (ja) 2014-03-05

Similar Documents

Publication Publication Date Title
BR112012006831A2 (pt) corpo plano na forma de um cartão com chip para análise bioquímica e método para o uso do mesmo
BR112014011935A2 (pt) elemento de cobertura, método e módulo de tratamento para tratar uma amostra biológica sobre um substrato
ES2531400T3 (es) Tarjeta de prueba
BR112013024190A2 (pt) microdispositivo para detectar ou tratar doença e métodos para fabricar microdispositivo e para detectar doença em indivíduo em necessidade do mesmo
BR112015028729A2 (pt) lente oftálmica com um sistema microfluídico
BRPI0818615A2 (pt) Sistema de aspiração para remoção de líquido descarregado pelo corpo humano, e sensor de líquido para o mesmo.
BR112017002536A2 (pt) dispositivo de análise de fluxo lateral
BRPI0920586A2 (pt) dispositivo de separacao para uso na separacao ,caracterizacao e/ou identificacao de micro-organismos.
WO2009053928A3 (en) Cartridge for a biological sample
DK1960771T3 (da) Sensorer
BRPI0510013B8 (pt) dispositivo intravaginal para uso em um corpo mamífero, método de produção de um dispositivo intravaginal e aparelho para a produção de um dispositivo intravaginal
BR112015029245A2 (pt) dispositivo de análise de fluido compacto e método de fabricação
BRPI0612623A2 (pt) dispositivo sensor, sistema e método para determinar a concentração de pelo menos uma espécie de alvos em um fluido contendo pelo menos uma espécie de rótulos magnéticos polarizáveis ou polarizados
EA201200789A1 (ru) Смешивание и доставка текучих сред в микроструйных системах
BRPI0909620A2 (pt) "dispositivo microfluídico para detectar a presença de um ou mais análitos em uma amostra de saliva, método para detectar a presença de um ou mais análitos em uma amostra de saliva e método para detectar em um dispositivo microfluídico um análito e uma amostra de saliva que copreende a mucina"
BRPI0711344A2 (pt) unidade de teste diagnóstico com recipiente para porta-teste
BR112014016762A8 (pt) módulo de troca de calor, parede polimérica flexível, e, tanque de biorreator com defletores amarrados encamisado
BR112013018236A2 (pt) microcarreadores codificados aprimorados, sistema de ensaio que usa os mesmos e método para realização de um ensaio
AR067755A1 (es) Sistema detector microfluidico o articulo para estudiar una muestra que contiene un analito
BRPI0920005A2 (pt) instrumento e sistema para produzir uma amostra de um líquido de corpo e para análise do mesmo
WO2008006501A8 (en) Disposable for analyzing a liquid sample by nucleic acid amplification
WO2002085185A3 (en) Hydrophilic diagnostic devices
BRPI1013107A2 (pt) Processo e dispositivo para a detecção de contaminantes em um fluido
BRPI0916101A2 (pt) "método para determinar o estágio de uma gravidez, dispositivo adaptado para detectar os níveis/a quantidade de hpl ou de um fragmento do mesmo em uma amostra de fluido corpóreo derivado de uma fêmea humana, kit e uso de um anticorpo anti-hpl"
BR112015012611B8 (pt) módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: BOEHRINGER INGELHEIM VETMEDICA GMBH (DE)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]

Free format text: O DEPOSITANTE DEVE RESPONDER A EXIGENCIA FORMULADA NESTE PARECER POR MEIO DO SERVICO DE CODIGO 206 EM ATE 60 (SESSENTA) DIAS, A PARTIR DA DATA DE PUBLICACAO NA RPI, SOB PENA DO ARQUIVAMENTO DO PEDIDO, DE ACORDO COM O ART. 34 DA LPI.PUBLIQUE-SE A EXIGENCIA (6.20).

B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/09/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 13A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2741 DE 18-07-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.