BR112015012611B8 - módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico - Google Patents

módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico

Info

Publication number
BR112015012611B8
BR112015012611B8 BR112015012611A BR112015012611A BR112015012611B8 BR 112015012611 B8 BR112015012611 B8 BR 112015012611B8 BR 112015012611 A BR112015012611 A BR 112015012611A BR 112015012611 A BR112015012611 A BR 112015012611A BR 112015012611 B8 BR112015012611 B8 BR 112015012611B8
Authority
BR
Brazil
Prior art keywords
heat exchange
reactor system
pharmaceutical
chemical
exchange module
Prior art date
Application number
BR112015012611A
Other languages
English (en)
Other versions
BR112015012611B1 (pt
BR112015012611A2 (pt
Inventor
R Tuohey Colin
D Crowell Joseph
Clapp Kenneth
M Galliher Parrish
Mitchell Peter
L Damren Richard
Erdenberger Thomas
Original Assignee
Ge Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/691,998 external-priority patent/US9340763B2/en
Application filed by Ge Healthcare Bio Sciences Corp filed Critical Ge Healthcare Bio Sciences Corp
Publication of BR112015012611A2 publication Critical patent/BR112015012611A2/pt
Publication of BR112015012611B1 publication Critical patent/BR112015012611B1/pt
Publication of BR112015012611B8 publication Critical patent/BR112015012611B8/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/18Stationary reactors having moving elements inside
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0053Details of the reactor
    • B01J19/006Baffles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/22Transparent or translucent parts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/26Constructional details, e.g. recesses, hinges flexible
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/28Constructional details, e.g. recesses, hinges disposable or single use
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18Flow directing inserts
    • C12M27/20Baffles; Ribs; Ribbons; Auger vanes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18Heat exchange systems, e.g. heat jackets or outer envelopes
    • C12M41/24Heat exchange systems, e.g. heat jackets or outer envelopes inside the vessel
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28DHEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
    • F28D1/00Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or motor car radiators
    • F28D1/06Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or motor car radiators with the heat-exchange conduits forming part of, or being attached to, the tank containing the body of fluid
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28FDETAILS OF HEAT-EXCHANGE AND HEAT-TRANSFER APPARATUS, OF GENERAL APPLICATION
    • F28F7/00Elements not covered by group F28F1/00, F28F3/00 or F28F5/00
    • F28F7/02Blocks traversed by passages for heat-exchange media
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049Controlling or regulating processes
    • B01J2219/00051Controlling the temperature
    • B01J2219/00074Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00076Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements inside the reactor
    • B01J2219/00083Coils
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049Controlling or regulating processes
    • B01J2219/00051Controlling the temperature
    • B01J2219/00074Controlling the temperature by indirect heating or cooling employing heat exchange fluids
    • B01J2219/00076Controlling the temperature by indirect heating or cooling employing heat exchange fluids with heat exchange elements inside the reactor
    • B01J2219/00085Plates; Jackets; Cylinders
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00761Details of the reactor
    • B01J2219/00763Baffles
    • B01J2219/00765Baffles attached to the reactor wall
    • B01J2219/00768Baffles attached to the reactor wall vertical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
  • Details Of Heat-Exchange And Heat-Transfer (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico. é descrito um módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico que inclui um corpo configurado para ser descartado no sistema de reator tendo um recipiente de reagente substituível interno. o corpo pode incluir adicionalmente pelo menos uma superfície termicamente condutora adaptada para entrar em contato com o recipiente de reagente substituível interno para facilitar transferência de calor. além disto, o módulo de troca de calor pode incluir um trocador de calor disposto no corpo do módulo e pode incluir um trajeto de circulação do fluido através do qual um fluido de troca de calor pode ser circulado.
BR112015012611A 2012-12-03 2013-12-03 módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico BR112015012611B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/691,998 2012-12-03
US13/691,998 US9340763B2 (en) 2008-03-25 2012-12-03 Temperature controlling surfaces and support structures
PCT/US2013/072742 WO2014089000A2 (en) 2012-12-03 2013-12-03 Temperature controlling surfaces and support structures

Publications (3)

Publication Number Publication Date
BR112015012611A2 BR112015012611A2 (pt) 2017-07-11
BR112015012611B1 BR112015012611B1 (pt) 2020-09-01
BR112015012611B8 true BR112015012611B8 (pt) 2020-09-24

Family

ID=50030441

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015012611A BR112015012611B8 (pt) 2012-12-03 2013-12-03 módulo de troca de calor para uso em um sistema de reator químico, farmacêutico ou biológico

Country Status (6)

Country Link
EP (1) EP2926076B1 (pt)
JP (1) JP6938007B2 (pt)
KR (1) KR20150092135A (pt)
CN (2) CN110849172A (pt)
BR (1) BR112015012611B8 (pt)
WO (1) WO2014089000A2 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109072160B (zh) * 2016-05-13 2022-03-01 思拓凡瑞典有限公司 用于一次性生物反应器和混合器的支承容器
US20190316073A1 (en) * 2016-12-09 2019-10-17 Chin-Hsing CHUO Fermentation tank
EP3691781A4 (en) * 2017-10-03 2021-01-20 Abec, Inc. REACTOR SYSTEMS
JP7393802B2 (ja) * 2020-06-12 2023-12-07 亞太燃料電池科技股▲分▼有限公司 熱エネルギー転送装置
DE102020005550A1 (de) 2020-09-10 2022-03-10 Sartorius Stedim Biotech Gmbh Bioreaktorsysteme sowie Verfahren zum Betreiben eines Bioprozesses
IT202100014714A1 (it) * 2021-06-08 2021-09-08 Biagi Angelo Zullo Reattore di plastica incamiciato per la produzione di olive da mensa
CN115388676A (zh) * 2022-08-24 2022-11-25 长虹美菱股份有限公司 一种聚氨酯原料水冷换热器及其控制方法
CN115854648B (zh) * 2022-11-17 2024-07-09 长虹美菱股份有限公司 一种冰箱柜聚氨酯原料水冷热交换系统及方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963690A (en) * 1974-10-07 1976-06-15 The Dow Chemical Company Polymerization of ethylene in stirred autoclave with cooled inner wall
JPS54124096U (pt) * 1978-02-20 1979-08-30
US4808159A (en) * 1987-03-16 1989-02-28 Minnesota Mining And Manufacturing Company Apparatus and method for admixture blood warming
CN2311745Y (zh) * 1997-10-22 1999-03-24 周通 搪玻璃复合套筒式换热器
AU2001255341A1 (en) * 2000-04-13 2001-10-30 Jose P. Arencibia Jr. Temperature controlled reaction vessel
US6351381B1 (en) * 2001-06-20 2002-02-26 Thermal Corp. Heat management system
US6837610B2 (en) * 2002-09-27 2005-01-04 Ilc Dover Lpp Bioprocess container, bioprocess container mixing device and method of use thereof
US7870891B2 (en) * 2004-05-29 2011-01-18 Kilr-Chilr, Llc Systems, devices and methods for regulating temperatures of tanks, containers and contents therein
DK1773976T4 (da) * 2004-06-04 2020-02-10 Global Life Sciences Solutions Usa Llc Engangsbioreaktorsystemer og -fremgangsmåder
EP2018416B1 (en) * 2006-05-13 2018-10-24 Pall Life Sciences Belgium Disposable bioreactor
EP2044190B1 (en) 2006-06-16 2017-09-13 GE Healthcare Bio-Sciences Corp. Gas delivery configurations, foam control systems, and bag molding methods and articles for collapsible bag vessels and bioreactors
US20100075405A1 (en) * 2007-02-15 2010-03-25 Broadley-James Corporation Bioreactor jacket
CN101303213A (zh) * 2007-05-11 2008-11-12 湖南工业大学 一种重污垢型螺旋流道结构高效传热装置
EP2018906A1 (en) * 2007-07-19 2009-01-28 Methanol Casale S.A. Heat exchange unit for isothermal chemical reactors
US20090134173A1 (en) * 2007-11-26 2009-05-28 Paul Mueller Company Baffle System for a Vessel
CN201170676Y (zh) * 2008-01-17 2008-12-24 黄洪滔 一种蓄冷箱
EP2247707A1 (en) * 2008-01-25 2010-11-10 Xcellerex, Inc. Bag wrinkel remover, leak detection systems, and electromagnetic agitation for liquid containment systems
US20090242173A1 (en) * 2008-03-25 2009-10-01 Peter Mitchell Temperature control system
JP5792177B2 (ja) 2009-09-30 2015-10-07 ジーイー・ヘルスケア・バイオサイエンス・コーポレイション 使い捨てバイオリアクター凝縮バッグおよびフィルターヒーター

Also Published As

Publication number Publication date
EP2926076A2 (en) 2015-10-07
WO2014089000A2 (en) 2014-06-12
BR112015012611B1 (pt) 2020-09-01
JP6938007B2 (ja) 2021-09-22
EP2926076B1 (en) 2020-06-03
KR20150092135A (ko) 2015-08-12
BR112015012611A2 (pt) 2017-07-11
JP2016500433A (ja) 2016-01-12
WO2014089000A3 (en) 2014-09-18
CN110849172A (zh) 2020-02-28
CN104903674A (zh) 2015-09-09

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/12/2013, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REF. RPI 2591 DE 01/09/2020 QUANTO AO ENDERECO.

B25D Requested change of name of applicant approved

Owner name: GLOBAL LIFE SCIENCES SOLUTIONS USA LLC (US)

B25G Requested change of headquarter approved

Owner name: GLOBAL LIFE SCIENCES SOLUTIONS USA LLC (US)