BR112012000656A2 - novos derivados de tiofenocarboxamida e uso farmacêutico dos mesmos. - Google Patents
novos derivados de tiofenocarboxamida e uso farmacêutico dos mesmos.Info
- Publication number
- BR112012000656A2 BR112012000656A2 BR112012000656A BR112012000656A BR112012000656A2 BR 112012000656 A2 BR112012000656 A2 BR 112012000656A2 BR 112012000656 A BR112012000656 A BR 112012000656A BR 112012000656 A BR112012000656 A BR 112012000656A BR 112012000656 A2 BR112012000656 A2 BR 112012000656A2
- Authority
- BR
- Brazil
- Prior art keywords
- novel
- pharmaceutical use
- thiophenecarboxamide derivatives
- thiophenecarboxamide
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009152741A JP2011006366A (ja) | 2009-06-26 | 2009-06-26 | 新規チオフェンカルボキサミド誘導体及びその医薬用途 |
| PCT/JP2010/060916 WO2010150899A1 (ja) | 2009-06-26 | 2010-06-26 | 新規チオフェンカルボキサミド誘導体及びその医薬用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112012000656A2 true BR112012000656A2 (pt) | 2016-11-16 |
Family
ID=43386666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012000656A BR112012000656A2 (pt) | 2009-06-26 | 2010-06-26 | novos derivados de tiofenocarboxamida e uso farmacêutico dos mesmos. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20120101137A1 (pt) |
| EP (1) | EP2447265A4 (pt) |
| JP (1) | JP2011006366A (pt) |
| KR (1) | KR20120095838A (pt) |
| CN (1) | CN102471333A (pt) |
| AU (1) | AU2010263527A1 (pt) |
| BR (1) | BR112012000656A2 (pt) |
| CA (1) | CA2766387A1 (pt) |
| MX (1) | MX2012000185A (pt) |
| RU (1) | RU2012102677A (pt) |
| WO (1) | WO2010150899A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013212994A (ja) * | 2010-06-22 | 2013-10-17 | Sanwa Kagaku Kenkyusho Co Ltd | 新規チオフェンカルボキサミド誘導体及びその医薬用途 |
| CN104710403A (zh) * | 2015-02-11 | 2015-06-17 | 佛山市赛维斯医药科技有限公司 | 一类卤代噻吩酰胺甲苯类双靶点抑制剂及其用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5840917A (en) * | 1995-09-26 | 1998-11-24 | Takeda Chemical Industries, Ltd. | Phosphorylamides, their preparation and use |
| JPH10324632A (ja) * | 1997-03-25 | 1998-12-08 | Takeda Chem Ind Ltd | 医薬組成物 |
| MXPA05003391A (es) | 2002-10-03 | 2005-06-22 | Hoffmann La Roche | Indol-3-carboxamidas como activadores de glucocinasa. |
| KR100970294B1 (ko) * | 2005-06-08 | 2010-07-15 | 니뽄 다바코 산교 가부시키가이샤 | 복소환 화합물 |
| TW200738701A (en) * | 2005-07-26 | 2007-10-16 | Du Pont | Fungicidal carboxamides |
| EP1948614A2 (en) * | 2005-11-18 | 2008-07-30 | Takeda San Diego, Inc. | Glucokinase activators |
| US7638541B2 (en) * | 2006-12-28 | 2009-12-29 | Metabolex Inc. | 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine |
| CA2679185A1 (en) * | 2007-02-28 | 2008-09-04 | Advinus Therapeutics Private Limited | 2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application |
| JP2010529109A (ja) | 2007-06-08 | 2010-08-26 | アドビナス セラピュティックス プライベート リミテッド | グルコキナーゼ活性化因子としてのピロール−２−カルボキサミド誘導体、そのプロセス及び薬学的応用 |
| JPWO2008156174A1 (ja) * | 2007-06-21 | 2010-08-26 | 大正製薬株式会社 | ピラジンアミド化合物 |
-
2009
- 2009-06-26 JP JP2009152741A patent/JP2011006366A/ja not_active Withdrawn
-
2010
- 2010-06-26 BR BR112012000656A patent/BR112012000656A2/pt not_active IP Right Cessation
- 2010-06-26 KR KR1020127001897A patent/KR20120095838A/ko not_active Application Discontinuation
- 2010-06-26 MX MX2012000185A patent/MX2012000185A/es not_active Application Discontinuation
- 2010-06-26 CA CA2766387A patent/CA2766387A1/en not_active Abandoned
- 2010-06-26 CN CN2010800364065A patent/CN102471333A/zh active Pending
- 2010-06-26 US US13/380,664 patent/US20120101137A1/en not_active Abandoned
- 2010-06-26 AU AU2010263527A patent/AU2010263527A1/en not_active Abandoned
- 2010-06-26 EP EP10792217A patent/EP2447265A4/en not_active Withdrawn
- 2010-06-26 RU RU2012102677/04A patent/RU2012102677A/ru unknown
- 2010-06-26 WO PCT/JP2010/060916 patent/WO2010150899A1/ja active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010150899A1 (ja) | 2010-12-29 |
| US20120101137A1 (en) | 2012-04-26 |
| AU2010263527A1 (en) | 2012-02-02 |
| KR20120095838A (ko) | 2012-08-29 |
| JP2011006366A (ja) | 2011-01-13 |
| MX2012000185A (es) | 2012-02-28 |
| RU2012102677A (ru) | 2013-08-10 |
| EP2447265A1 (en) | 2012-05-02 |
| CN102471333A (zh) | 2012-05-23 |
| CA2766387A1 (en) | 2010-12-29 |
| EP2447265A4 (en) | 2013-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |