BR112012000420B8 - micro carreador para dispensação de droga - Google Patents

micro carreador para dispensação de droga

Info

Publication number
BR112012000420B8
BR112012000420B8 BR112012000420A BR112012000420A BR112012000420B8 BR 112012000420 B8 BR112012000420 B8 BR 112012000420B8 BR 112012000420 A BR112012000420 A BR 112012000420A BR 112012000420 A BR112012000420 A BR 112012000420A BR 112012000420 B8 BR112012000420 B8 BR 112012000420B8
Authority
BR
Brazil
Prior art keywords
micro
carrier
drug
dispensing
sites
Prior art date
Application number
BR112012000420A
Other languages
English (en)
Other versions
BR112012000420B1 (pt
BR112012000420A2 (pt
Inventor
C Yu Chris
Yu He
Original Assignee
Anpac Bio Medical Science Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anpac Bio Medical Science Co Ltd filed Critical Anpac Bio Medical Science Co Ltd
Publication of BR112012000420A2 publication Critical patent/BR112012000420A2/pt
Publication of BR112012000420B1 publication Critical patent/BR112012000420B1/pt
Publication of BR112012000420B8 publication Critical patent/BR112012000420B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Micromachined devices; Microelectromechanical systems [MEMS]; Devices obtained by lithographic treatment of silicon; Devices comprising chips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

micro-carreador para dispensação de droga. um método de dispensação de drogas é descrito. um micro-carreador dispensa uma droga encapsulada diretamente para locais marcados sem interações significantes com outros componentes no sistema biológico. em uma modalidade, um micro-carreador é primeiro dispensado a uma área geral para tratamento. ele então escaneia a área e seletivamente se afixa para local de célula ou localização de órgão a ser tratados. finalmente a droga desejada contida no micro-carreador é liberada para o local afixado. em outra modalidade, um micro-dispositivo é primeiro usado para processar a área geral para intensificar diferenciação em propriedades entre células e células não saudáveis. droga é encapsulada no micro-carreador para preferencialmente afixar nos locais marcados.finalmente,droga é liberada do micro-carreador dentro dos locais. tais micro-careadores preferencialmente contêm múltiplas funções compreendidas de pelo menos dois de: sensoriamento,análise,processo lógico,tratamento de face,detecção de posição, movimento, injeção, dispensação, funções de corte, funções de remoção, biodegradação e desintegração.
BR112012000420A 2009-07-07 2010-07-03 micro carreador para dispensação de droga BR112012000420B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12/498,698 US10105317B2 (en) 2009-07-07 2009-07-07 Method of drug delivery
US12/498,698 2009-07-07
PCT/US2010/041001 WO2011005720A1 (en) 2009-07-07 2010-07-03 Method of drug delivery

Publications (3)

Publication Number Publication Date
BR112012000420A2 BR112012000420A2 (pt) 2016-04-12
BR112012000420B1 BR112012000420B1 (pt) 2020-09-29
BR112012000420B8 true BR112012000420B8 (pt) 2021-07-27

Family

ID=43427656

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012000420A BR112012000420B8 (pt) 2009-07-07 2010-07-03 micro carreador para dispensação de droga

Country Status (13)

Country Link
US (1) US10105317B2 (pt)
EP (1) EP2451443B1 (pt)
JP (2) JP5950405B2 (pt)
KR (1) KR20120059495A (pt)
CN (1) CN102481259A (pt)
AU (1) AU2010270766B2 (pt)
BR (1) BR112012000420B8 (pt)
CA (2) CA2766766C (pt)
IL (1) IL217072A (pt)
IN (1) IN2012DN00909A (pt)
NZ (1) NZ597164A (pt)
WO (1) WO2011005720A1 (pt)
ZA (1) ZA201109514B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10624847B2 (en) * 2011-08-02 2020-04-21 AnPac BioMedical Science Co., Ltd. Decomposable apparatus and methods for fabricating same
TW202109037A (zh) 2012-07-16 2021-03-01 大陸商昌和生物醫學科技（揚州）有限公司 增強疾病檢測與鑒定的器件與方法
US10802014B2 (en) * 2013-01-07 2020-10-13 Anpac Bio-Medical Science (Shanghai) Co., Ltd. Apparatus for improved disease detection
WO2014139482A1 (en) 2013-03-15 2014-09-18 Anpac Bio-Medical Science (Lishui) Co., Ltd. Methods and apparatus for enhanced detection of diseases
CN105695327B (zh) 2016-04-06 2018-09-07 京东方科技集团股份有限公司 一种纳米机器人
US11266344B2 (en) 2016-09-21 2022-03-08 Samsung Electronics Co., Ltd. Method for measuring skin condition and electronic device therefor
CN106448794B (zh) * 2016-10-14 2018-08-07 武汉理工大学 半导体微纳米粒子定向运动控制方法
EP3952726A4 (en) * 2019-04-08 2023-06-07 Velanidi Technologies LLC SYSTEM, APPARATUS AND METHOD FOR CAPTURE, DETECTION AND IMPLEMENTATION IN A MICROMETRIC TO NANOMETRIC ENVIRONMENT

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3176097A (en) 1997-06-13 1998-12-30 Medinova Medical Consulting Gmbh Drug targeting system, method of its preparation and its use
US6165440A (en) 1997-07-09 2000-12-26 Board Of Regents, The University Of Texas System Radiation and nanoparticles for enhancement of drug delivery in solid tumors
US20030007991A1 (en) 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
US6773823B2 (en) 2000-04-07 2004-08-10 University Of New Orleans Research And Technology Foundation, Inc. Sequential synthesis of core-shell nanoparticles using reverse micelles
US6663615B1 (en) * 2001-09-04 2003-12-16 The Ohio State University Dual stage microvalve and method of use
CA2487940C (en) 2002-06-05 2009-09-22 University Of Florida Ophthalmic drug delivery system
JP2004231575A (ja) * 2003-01-30 2004-08-19 Terumo Corp 薬剤を特定の標的部位まで輸送するための組成物
WO2004101023A2 (en) * 2003-05-06 2004-11-25 Becton Dickinson And Company A method for altering insulin pharmacokinetics
US20040236278A1 (en) 2003-05-22 2004-11-25 Atrium Medical Corp. Therapeutic agent delivery
PT1704585T (pt) 2003-12-19 2017-05-05 Univ North Carolina Chapel Hill Métodos para fabricar microestruturas e nanoestruturas isoladas usando litografia suave ou impressão litográfica
US7182894B2 (en) 2004-03-12 2007-02-27 Council Of Scientific & Industrial Research Process for the preparation of free standing membranes
US8019413B2 (en) 2007-03-19 2011-09-13 The Invention Science Fund I, Llc Lumen-traveling biological interface device and method of use
WO2006006462A1 (ja) 2004-07-08 2006-01-19 Mitsubishi Materials Corporation 金属微粒子の製造方法、およびそれにより製造された金属微粒子、並びにそれを含有してなる組成物、光吸収材、応用品
US20060040390A1 (en) 2004-08-19 2006-02-23 Minor John S Jr Device, method, system, and program for intelligent in vivo cell-level chemical or genetic material delivery
CN101107038A (zh) * 2005-01-18 2008-01-16 皇家飞利浦电子股份有限公司 电控胶囊
US20060283465A1 (en) 2005-06-16 2006-12-21 Nickel Janice H Smart drug delivery system and a method of implementation thereof
EP2460868A3 (en) 2006-01-06 2013-06-19 National University of Singapore Method of preparing nano-structured material(s) and uses thereof
US20080241264A1 (en) * 2006-11-13 2008-10-02 Solomon Research Llc System and methods for collective nanorobotics for medical applications
WO2008112565A2 (en) 2007-03-09 2008-09-18 Anthony Manganaro Method and composition for treating cancer
US9714941B2 (en) 2007-07-31 2017-07-25 Massachusetts Institute Of Technology Bio-sensing nanodevice

Also Published As

Publication number Publication date
EP2451443B1 (en) 2017-05-03
CA3073148A1 (en) 2011-01-13
US20110008446A1 (en) 2011-01-13
KR20120059495A (ko) 2012-06-08
BR112012000420B1 (pt) 2020-09-29
JP6174757B2 (ja) 2017-08-02
EP2451443A1 (en) 2012-05-16
EP2451443A4 (en) 2014-03-12
NZ597164A (en) 2014-07-25
JP2012532675A (ja) 2012-12-20
CA2766766A1 (en) 2011-01-13
JP5950405B2 (ja) 2016-07-13
AU2010270766B2 (en) 2016-09-15
BR112012000420A2 (pt) 2016-04-12
IL217072A0 (en) 2012-02-29
ZA201109514B (en) 2012-09-26
CN102481259A (zh) 2012-05-30
IL217072A (en) 2017-06-29
JP2016193919A (ja) 2016-11-17
CA2766766C (en) 2020-04-07
IN2012DN00909A (pt) 2015-04-03
US10105317B2 (en) 2018-10-23
WO2011005720A1 (en) 2011-01-13
AU2010270766A1 (en) 2012-01-19

Similar Documents

Publication Publication Date Title
BR112012000420B8 (pt) micro carreador para dispensação de droga
Pereira et al. Influence of Aloe vera on water absorption and enzymatic in vitro degradation of alginate hydrogel films
Saini et al. Nanotechnology: the future medicine
Wang et al. Cell-in-cell death is not restricted by caspase-3 deficiency in MCF-7 cells
Luchenko et al. Schedule-dependent synergy of histone deacetylase inhibitors with DNA damaging agents in small cell lung cancer
WO2008058683A3 (de) Anordnung und verfahren zur analyse biologischer proben
Huang et al. A rapid and sensitive assay based on particle analysis for cell degranulation detection in basophils and mast cells
ATE447941T1 (de) Pharmazeutische vorrichtung für die verabreichung von substanzen an patienten
WO2010093861A3 (en) System, method and device for tissue-based diagnosis
BRPI1006215A2 (pt) " anticorpos multiespecíficos, ácido nucleico, célula hospedeira, método de produção de um anticorpo, imunoconjugado, formulação farmacêutica, método de tratamento, método de inibição de uma atividade bíologica e uso do anticorpo "
MX366369B (es) Metodo para un ensayo de deteccion de farmacos basado en celulas y el uso del mismo.
FR2901141B1 (fr) Dispositif et procede de traitement, notamment de sterilisation d'objets
Fetz et al. Localized delivery of Cl-amidine from electrospun polydioxanone templates to regulate acute neutrophil NETosis: a preliminary evaluation of the PAD4 inhibitor for tissue engineering
TW200730208A (en) Material dispenser with a solenoid lock
Li et al. Studies on the in vitro and in vivo degradation behavior of amino acid derivative-based organogels
Silina et al. Comparative Analysis of the Effectiveness of Some Biological Injected Wound Healing Stimulators and Criteria for Its Evaluation
CL2004000884A1 (es) Composicion farmaceutica en forma de hidrogel que contiene un diester de acido carbonico, un alquilalcohol c2-c4, por lo menos una sustancia activa y una matriz de polimero; uso en el tratamiento de carencias esteroidales.
TW200801184A (en) Methods for delivering extracellular target into cells
Ahmad et al. Retained sponge after abdominal surgery.
Callahan The concentration game: differential effects of bioactive signaling in 2D and 3D culture
Chen Tumor cell invasion assay
Wiwanitkit CD44 and cancer nanotherapy
CN201720063U (zh) 一种鱼虾蟹早期幼体生物毒理实验容器
Dineva et al. Relationship of nitrate levels in follicular fluids (FFLs) and rate of apoptotic human granulosa luteinized cells (GLCs) with COH/IVF outcome
Spero et al. Driven Microbead Rheology of Fibrin Gels

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 29/09/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REFERENTE AO DESPACHO 16.1 PUBLICADO NA RPI 2595 DE 29.09.2020, QUANDO AO ENDERECO DO TITULAR

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 03/07/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO

B25A Requested transfer of rights approved

Owner name: CHANGWEI SYSTEM TECHNOLOGY (SHANGHAI) CO., LTD. (CN)

B25A Requested transfer of rights approved

Owner name: NINGKASAI TECHNOLOGY (SHANGHAI) CO, LTD. (CN)