BR0317520A - Composições de inibidores de proteìna de transferência de ésteres de colesterilo e inibidores de hmg-coa redutase - Google Patents
Composições de inibidores de proteìna de transferência de ésteres de colesterilo e inibidores de hmg-coa redutaseInfo
- Publication number
- BR0317520A BR0317520A BR0317520-0A BR0317520A BR0317520A BR 0317520 A BR0317520 A BR 0317520A BR 0317520 A BR0317520 A BR 0317520A BR 0317520 A BR0317520 A BR 0317520A
- Authority
- BR
- Brazil
- Prior art keywords
- inhibitors
- hmg
- transfer protein
- compositions
- coa reductase
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 239000003354 cholesterol ester transfer protein inhibitor Substances 0.000 title abstract 3
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 title abstract 2
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 title abstract 2
- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 title 1
- 102000012336 Cholesterol Ester Transfer Proteins Human genes 0.000 abstract 2
- 108010061846 Cholesterol Ester Transfer Proteins Proteins 0.000 abstract 2
- 239000002156 adsorbate Substances 0.000 abstract 2
- 229940125881 cholesteryl ester transfer protein inhibitor Drugs 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 239000007787 solid Substances 0.000 abstract 2
- OWTYWMJVQZQWFH-JQTKPCACSA-N CE(20:1(11Z)) Chemical group C12CC[C@]3(C)C([C@H](C)CCCC(C)C)CCC3C2CC=C2[C@]1(C)CC[C@H](OC(=O)CCCCCCCCC\C=C/CCCCCCCC)C2 OWTYWMJVQZQWFH-JQTKPCACSA-N 0.000 abstract 1
- 229940121649 protein inhibitor Drugs 0.000 abstract 1
- 239000012268 protein inhibitor Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43532802P | 2002-12-20 | 2002-12-20 | |
| PCT/IB2003/006170 WO2004056395A1 (en) | 2002-12-20 | 2003-12-18 | Compositions of cholesteryl ester transfer protein inhibitors and hmg-coa reductase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0317520A true BR0317520A (pt) | 2005-11-16 |
Family
ID=32682218
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0317520-0A BR0317520A (pt) | 2002-12-20 | 2003-12-18 | Composições de inibidores de proteìna de transferência de ésteres de colesterilo e inibidores de hmg-coa redutase |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040132771A1 (enExample) |
| EP (1) | EP1578448A1 (enExample) |
| JP (1) | JP2006512361A (enExample) |
| AU (2) | AU2003285703A1 (enExample) |
| BR (1) | BR0317520A (enExample) |
| CA (1) | CA2510458A1 (enExample) |
| MX (1) | MXPA05006167A (enExample) |
| WO (2) | WO2004056395A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EE200400024A (et) * | 2001-06-21 | 2004-06-15 | Pfizer Products Inc. | Kolesterüülestri ülekandevalgu inhibiitorite iseemulgeeruvad formulatsioonid |
| KR20050088190A (ko) * | 2002-12-20 | 2005-09-02 | 화이자 프로덕츠 인코포레이티드 | 콜레스테릴 에스터 전달 단백질 억제제 및 hmg-coa환원 효소 억제제를 포함하는 투약 형태 |
| BRPI0410840A (pt) | 2003-05-30 | 2006-07-04 | Ranbaxy Lab Ltd | derivados substituìdos de pirrol, composição farmacêutica contendo os mesmos e processo para sua preparação |
| JP2008521878A (ja) * | 2004-12-02 | 2008-06-26 | ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー | 非晶質アトルバスタチンの医薬組成物及びその製造のための方法 |
| CA2601762A1 (en) * | 2005-02-03 | 2006-08-10 | Pfizer Products Inc. | Dosage forms providing controlled and immediate release of cholesteryl ester transfer protein inhibitors and immediate release of hmg-coa reductase inhibitors |
| WO2006085217A2 (en) * | 2005-02-08 | 2006-08-17 | Pfizer Products Inc. | Solid adsorbates of hydrophobic drugs |
| EP1893178A1 (en) * | 2005-05-31 | 2008-03-05 | Pfizer Products Incorporated | PHARMACEUTICAL COMPOSITIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG-CoA REDUCTASE INHIBITORS |
| JP2009514851A (ja) * | 2005-11-08 | 2009-04-09 | ランバクシー ラボラトリーズ リミテッド | (3r,5r)−7−[2−(4−フルオロフェニル)−5−イソプロピル−3−フェニル−4−[(4−ヒドロキシメチルフェニルアミノ)カルボニル]−ピロール−1−イル]−3,5−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法 |
| AR059838A1 (es) * | 2006-03-14 | 2008-04-30 | Ranbaxy Lab Ltd | Formulaciones para dosis estabilizantes de estatina |
| WO2007134158A2 (en) * | 2006-05-12 | 2007-11-22 | Drugtech Corporation | Granules comprising calcium carbonate, a binder and a porosity increasing agent, processes of manufacturing, use in therapy |
| US8099298B2 (en) * | 2007-02-14 | 2012-01-17 | Genelex, Inc | Genetic data analysis and database tools |
| CA2716671A1 (en) * | 2008-02-27 | 2009-09-03 | Thommen Medical Ag | Implant and method for the manufacture thereof |
| AU2009224418B2 (en) | 2008-03-11 | 2014-12-11 | Aska Pharmaceutical Co., Ltd. | Solid dispersion, pharmaceutical compositions containing the same, and processes for the production of both |
| JP2011525901A (ja) * | 2008-06-27 | 2011-09-29 | アブディ イブラヒム イラク サナイ ベ ティカレット アノニム シルケティ | ロスバスタチンカルシウム含有医薬組成物 |
| WO2010092925A1 (ja) * | 2009-02-12 | 2010-08-19 | あすか製薬株式会社 | 固体分散体とその医薬組成物、並びにそれらの製造方法 |
| US8877221B2 (en) | 2010-10-27 | 2014-11-04 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising calcium phosphate particles and statins and methods of using the same |
| US9107983B2 (en) | 2010-10-27 | 2015-08-18 | Warsaw Orthopedic, Inc. | Osteoconductive matrices comprising statins |
| WO2012170417A2 (en) | 2011-06-06 | 2012-12-13 | Warsaw Orthopedic, Inc. | Methods and compositions to enhance bone growth comprising a statin |
| WO2014121133A2 (en) | 2013-02-03 | 2014-08-07 | Genelex Corporation | Systems and methods for quantification and presentation of medical risk arising from unknown factors |
| US20200147032A1 (en) | 2018-11-14 | 2020-05-14 | Robert K. Prud'homme | Dihydromyricetin hot melt extrusion formulations and methods for forming them |
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| US35125A (en) * | 1862-04-29 | Improvement in spring-balances | ||
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| US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
| US4319039A (en) * | 1979-06-15 | 1982-03-09 | Merck & Co., Inc. | Preparation of ammonium salt of hypocholesteremic fermentation product |
| US4444784A (en) * | 1980-08-05 | 1984-04-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| DK149080C (da) * | 1980-06-06 | 1986-07-28 | Sankyo Co | Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre |
| US4450171A (en) * | 1980-08-05 | 1984-05-22 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| JPS5889191A (ja) * | 1981-11-20 | 1983-05-27 | Sankyo Co Ltd | 3−ヒドロキシ−ml−236b誘導体の製造法 |
| FR2525108B1 (fr) * | 1982-04-19 | 1989-05-12 | Elan Corp Ltd | Medicaments a haut degre de solubilite et procede pour leur obtention |
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| NZ529490A (en) * | 2001-06-22 | 2005-08-26 | Pfizer Prod Inc | Pharmaceutical compositions of adsorbates of amorphous drug |
| US20030099708A1 (en) * | 2001-10-29 | 2003-05-29 | Therics, Inc | Printing or dispensing a suspension such as three-dimensional printing of dosage forms |
| AU2003260239A1 (en) * | 2002-06-26 | 2004-01-19 | Tuo Jin | Solid dosage forms for rapid dissolution of poorly soluble drugs |
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-
2003
- 2003-10-06 US US10/678,145 patent/US20040132771A1/en not_active Abandoned
- 2003-12-18 JP JP2004561920A patent/JP2006512361A/ja active Pending
- 2003-12-18 CA CA002510458A patent/CA2510458A1/en not_active Abandoned
- 2003-12-18 EP EP03778668A patent/EP1578448A1/en not_active Withdrawn
- 2003-12-18 WO PCT/IB2003/006170 patent/WO2004056395A1/en not_active Ceased
- 2003-12-18 MX MXPA05006167A patent/MXPA05006167A/es not_active Application Discontinuation
- 2003-12-18 AU AU2003285703A patent/AU2003285703A1/en not_active Abandoned
- 2003-12-18 BR BR0317520-0A patent/BR0317520A/pt not_active IP Right Cessation
- 2003-12-18 WO PCT/IB2003/006240 patent/WO2004056396A1/en not_active Ceased
- 2003-12-18 AU AU2003285677A patent/AU2003285677A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006512361A (ja) | 2006-04-13 |
| CA2510458A1 (en) | 2004-07-08 |
| AU2003285703A1 (en) | 2004-07-14 |
| US20040132771A1 (en) | 2004-07-08 |
| EP1578448A1 (en) | 2005-09-28 |
| MXPA05006167A (es) | 2005-08-26 |
| WO2004056395A1 (en) | 2004-07-08 |
| AU2003285677A1 (en) | 2004-07-14 |
| WO2004056396A1 (en) | 2004-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |