BR0317259A - Complexos de e-2-metóxi-n-(3-{4-[3-metil-4-(6-metilpiridin-3-ilóxi)-fenil amino]- quinazolin-6-il}-alil)-acetamida, seus métodos de produção e utilização - Google Patents

Complexos de e-2-metóxi-n-(3-{4-[3-metil-4-(6-metilpiridin-3-ilóxi)-fenil amino]- quinazolin-6-il}-alil)-acetamida, seus métodos de produção e utilização

Info

Publication number
BR0317259A
BR0317259A BR0317259-7A BR0317259A BR0317259A BR 0317259 A BR0317259 A BR 0317259A BR 0317259 A BR0317259 A BR 0317259A BR 0317259 A BR0317259 A BR 0317259A
Authority
BR
Brazil
Prior art keywords
methylpyridin
yloxy
allyl
methoxy
methyl
Prior art date
Application number
BR0317259-7A
Other languages
English (en)
Inventor
Zheng Jane Li
Jason Albert Leonard
Andrew Vincent Trask
John Charles Kath
Daniel Tyler Richter
Carl Brian Thompson
Joel Morris
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0317259A publication Critical patent/BR0317259A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"COMPLEXOS DE E-2-METóXI-N-(3-(4-¢3-METIL-4-(6-METILPIRIDIN-3-ILóXI)-FENIL AMINO!- QUINAZOLIN-6-IL}-ALIL)ACETAMIDA, SEUS MéTODOS DE PRODUçãO E UTILIZAçãO". A invenção refere-se a complexos de E-2-Metóxi-N(3-{4-¢3-metil-4-(6-metilpiridin-3-ilóxi)-fenilamino!quinazoli n-6-il}-alil)-acetamida que têm a fórmula I abaixo. A invenção também se refere a composições farmacêuticas que contêm os complexos de fórmula I. A invenção refere-se adicionalmente a métodos de tratamento de doenças hiperproliferativas, tais como câncer, em mamíferos, especialmente seres humanos, por administração dos complexos acima e a métodos de preparação dos complexos acima. 1
BR0317259-7A 2002-12-19 2003-12-08 Complexos de e-2-metóxi-n-(3-{4-[3-metil-4-(6-metilpiridin-3-ilóxi)-fenil amino]- quinazolin-6-il}-alil)-acetamida, seus métodos de produção e utilização BR0317259A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43470002P 2002-12-19 2002-12-19
PCT/IB2003/005783 WO2004056802A1 (en) 2002-12-19 2003-12-08 Complexes of e-2-methoxy-n-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide, their method of production, and use

Publications (1)

Publication Number Publication Date
BR0317259A true BR0317259A (pt) 2005-11-08

Family

ID=32682089

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0317259-7A BR0317259A (pt) 2002-12-19 2003-12-08 Complexos de e-2-metóxi-n-(3-{4-[3-metil-4-(6-metilpiridin-3-ilóxi)-fenil amino]- quinazolin-6-il}-alil)-acetamida, seus métodos de produção e utilização

Country Status (21)

Country Link
US (1) US20050075354A1 (pt)
EP (1) EP1575936A1 (pt)
JP (1) JP2006512355A (pt)
KR (1) KR20050085835A (pt)
CN (1) CN1726208A (pt)
AR (1) AR042508A1 (pt)
AU (1) AU2003283743A1 (pt)
BR (1) BR0317259A (pt)
CA (1) CA2509140A1 (pt)
GT (1) GT200300287A (pt)
MX (1) MXPA05006582A (pt)
NL (1) NL1025072C2 (pt)
NO (1) NO20052803L (pt)
PA (1) PA8592501A1 (pt)
PE (1) PE20040915A1 (pt)
PL (1) PL377533A1 (pt)
RU (1) RU2005122659A (pt)
TW (1) TW200424191A (pt)
UY (1) UY28129A1 (pt)
WO (1) WO2004056802A1 (pt)
ZA (1) ZA200504621B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050192298A1 (en) * 2004-02-27 2005-09-01 Pfizer Inc Crystal forms of E-2-Methoxy-N-(3-{4-[3-methyl-4-(6-methyl-pyridin-3-yloxy)-phenylamino]-quinazolin-6-yl}-allyl)-acetamide
WO2006129168A2 (en) * 2005-06-03 2006-12-07 Pfizer Products Inc. Bicyclic derivatives for the treatment of abnormal cell growth
DK3150610T3 (da) 2010-02-12 2019-11-04 Pfizer Salte og polymorfer af 8-fluor-2-{4-[(methylamino}methyl]phenyl}-1,3,4,5-tetrahydro-6h-azepino[5,4,3-cd]indol-6-on
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884418B1 (en) * 1989-08-04 2005-04-26 Berlex Laboratories, Inc. Use of ligand-mimicking agents and anti-neoplastic drugs in cancer therapy
DZ3407A1 (pt) * 2000-06-22 2001-12-27 Pfizer Prod Inc
CA2462149C (en) * 2001-11-30 2010-06-22 Pfizer Products Inc. Processes for the preparation of substituted bicyclic derivatives for the treatment of abnormal cell growth
HUP0501069A2 (en) * 2001-12-12 2006-06-28 Pfizer Prod Inc Quinazoline derivatives for the treatment of abnormal cell growth
KR20040065259A (ko) * 2001-12-12 2004-07-21 화이자 프로덕츠 인크. Ｅ-2-메톡시-ｎ-(3-(4-(3-메틸-피리딘-3-일옥시)-페닐아미노)-퀴나졸린-6-일)-알릴)-아세트아미드의 염 형태, 그의제조 방법 및 그의 암 치료에 있어서의 용도

Also Published As

Publication number Publication date
NO20052803D0 (no) 2005-06-09
WO2004056802A1 (en) 2004-07-08
MXPA05006582A (es) 2005-08-16
US20050075354A1 (en) 2005-04-07
AU2003283743A1 (en) 2004-07-14
CN1726208A (zh) 2006-01-25
PA8592501A1 (es) 2004-09-16
UY28129A1 (es) 2004-07-30
CA2509140A1 (en) 2004-07-08
GT200300287A (es) 2004-11-30
NL1025072C2 (nl) 2007-07-24
ZA200504621B (en) 2006-03-29
JP2006512355A (ja) 2006-04-13
PL377533A1 (pl) 2006-02-06
NO20052803L (no) 2005-09-16
EP1575936A1 (en) 2005-09-21
AR042508A1 (es) 2005-06-22
TW200424191A (en) 2004-11-16
NL1025072A1 (nl) 2004-06-22
RU2005122659A (ru) 2006-01-20
KR20050085835A (ko) 2005-08-29
PE20040915A1 (es) 2005-01-18

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL: C07D 401/12, A61K 31/505, A61P 35/00

Ipc: C07D 401/12 (2011.01), A61K 31/505 (2011.01)

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.