BR0316476A - Composição e processo para tratar nefrite do lúpus - Google Patents

Composição e processo para tratar nefrite do lúpus

Info

Publication number
BR0316476A
BR0316476A BR0316476-4A BR0316476A BR0316476A BR 0316476 A BR0316476 A BR 0316476A BR 0316476 A BR0316476 A BR 0316476A BR 0316476 A BR0316476 A BR 0316476A
Authority
BR
Brazil
Prior art keywords
bflp0169
polynucleotide
composition
polynucleotides
antibody
Prior art date
Application number
BR0316476-4A
Other languages
English (en)
Inventor
Margot Otoole
William M Mounts
Negin Shojaee
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BR0316476A publication Critical patent/BR0316476A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"COMPOSIçãO E PROCESSO PARA TRATAR NEFRITE DO LúPUS". A presente invenção refere-se a novos polinucleotídeos BFLP0169 isolados e polipeptídeos codificados pelos polinucleotídeos BFLP0169. Também são providos anticorpos que se ligam imunoespecificamente a um polipeptídeo BFLP0169 ou qualquer derivado (incluindo derivado de fusão), variante, mutante ou fragmento do polipeptídeo, polinucleotídeo ou anticorpo BFLP0169. A invenção provê, adicionalmente, processos nos quais o polinucleotídeo, polinucleotídeo e anticorpo BFLP0169 são utilizados na detecção e tratamento de uma ampla faixa de estados patológicos, bem como outros usos.
BR0316476-4A 2002-11-21 2003-11-21 Composição e processo para tratar nefrite do lúpus BR0316476A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42809402P 2002-11-21 2002-11-21
PCT/US2003/037339 WO2004048521A2 (en) 2002-11-21 2003-11-21 Composition and method for treating lupus nephritis

Publications (1)

Publication Number Publication Date
BR0316476A true BR0316476A (pt) 2005-10-11

Family

ID=32393347

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0316476-4A BR0316476A (pt) 2002-11-21 2003-11-21 Composição e processo para tratar nefrite do lúpus

Country Status (9)

Country Link
US (3) US7060797B2 (pt)
EP (1) EP1578197A4 (pt)
JP (1) JP2006516388A (pt)
CN (1) CN1741741A (pt)
AU (1) AU2003294438A1 (pt)
BR (1) BR0316476A (pt)
CA (1) CA2506633A1 (pt)
MX (1) MXPA05005385A (pt)
WO (1) WO2004048521A2 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE427948T1 (de) * 2001-04-24 2009-04-15 Purdue Research Foundation Folat-mimetika und deren folatrezeptorbindende konjugate
ES2324708T3 (es) * 2002-05-15 2009-08-13 Endocyte, Inc. Conjugados de vitamina-mitomicina.
US7601332B2 (en) 2003-01-27 2009-10-13 Endocyte, Inc. Vitamin receptor binding drug delivery conjugates
EP1789391B1 (en) 2004-07-23 2017-06-28 Endocyte, Inc. Bivalent linkers and conjugates thereof
US7838657B2 (en) * 2004-12-03 2010-11-23 University Of Massachusetts Spinal muscular atrophy (SMA) treatment via targeting of SMN2 splice site inhibitory sequences
EP1863816B1 (en) * 2005-03-16 2014-06-25 Endocyte, Inc. Synthesis and purification of pteroic acid and conjugates thereof
EP1948241B1 (en) * 2005-08-19 2014-03-05 Endocyte, Inc. Multi-drug ligand conjugates
WO2007022493A2 (en) * 2005-08-19 2007-02-22 Endocyte, Inc. Ligand conjugates of vinca alkaloids, analogs, and derivatives
US20100104626A1 (en) * 2007-02-16 2010-04-29 Endocyte, Inc. Methods and compositions for treating and diagnosing kidney disease
AU2008224988A1 (en) * 2007-03-14 2008-09-18 Endocyte, Inc. Binding ligand linked drug delivery conjugates of tubulysins
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
US9138484B2 (en) 2007-06-25 2015-09-22 Endocyte, Inc. Conjugates containing hydrophilic spacer linkers
CA2703491C (en) 2007-10-25 2017-06-13 Endocyte, Inc. Tubulysins and processes for preparing
WO2013126797A1 (en) 2012-02-24 2013-08-29 Purdue Research Foundation Cholecystokinin b receptor targeting for imaging and therapy
US20140080175A1 (en) 2012-03-29 2014-03-20 Endocyte, Inc. Processes for preparing tubulysin derivatives and conjugates thereof
RU2670743C9 (ru) * 2012-05-11 2018-12-19 Файв Прайм Терапьютикс, Инк. Способы лечения состояний антителами, которые связывают рецептор колониестимулирующего фактора 1 (csf1r)
SG11201502896XA (en) 2012-10-16 2015-05-28 Endocyte Inc Drug delivery conjugates containing unnatural amino acids and methods for using
CN106170700A (zh) * 2014-01-20 2016-11-30 玛丽亚·阿黛尔·西尔维亚·丹尼杰奥派德4有限公司 用于狼疮肾炎的治疗性随访中的预测、诊断和监测的体外方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2004A (en) * 1841-03-12 Improvement in the manner of constructing and propelling steam-vessels
US2002A (en) * 1841-03-12 Tor and planter for plowing
US2003A (en) * 1841-03-12 Improvement in horizontal windivhlls
IL112873A (en) * 1994-03-08 2005-03-20 Wyeth Corp Rapamycin-fkbp12 binding proteins, their isolation and their use
US20030049804A1 (en) * 1999-06-25 2003-03-13 Markus Pompejus Corynebacterium glutamicum genes encoding metabolic pathway proteins
WO2001053312A1 (en) * 1999-12-23 2001-07-26 Hyseq, Inc. Novel nucleic acids and polypeptides
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
US20020197679A1 (en) * 2000-06-20 2002-12-26 Tang Y. Tom Novel nucleic acids and polypeptides
JP2005535290A (ja) * 2002-02-22 2005-11-24 ジェネンテック・インコーポレーテッド 免疫関連疾患の治療のための組成物と方法

Also Published As

Publication number Publication date
CA2506633A1 (en) 2004-06-10
JP2006516388A (ja) 2006-07-06
CN1741741A (zh) 2006-03-01
US7060797B2 (en) 2006-06-13
EP1578197A2 (en) 2005-09-28
AU2003294438A1 (en) 2004-06-18
US7491513B2 (en) 2009-02-17
US20090098132A1 (en) 2009-04-16
MXPA05005385A (es) 2005-08-03
US20060228356A1 (en) 2006-10-12
US20040209284A1 (en) 2004-10-21
WO2004048521A3 (en) 2005-06-02
WO2004048521A2 (en) 2004-06-10
EP1578197A4 (en) 2006-05-17

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A. ANUIDADE(S),

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.