BR0316108A - Derivados de fenilalquil e piridilalquil piperazina e composição farmacêutica compreendendo os mesmos - Google Patents
Derivados de fenilalquil e piridilalquil piperazina e composição farmacêutica compreendendo os mesmosInfo
- Publication number
- BR0316108A BR0316108A BR0316108-0A BR0316108A BR0316108A BR 0316108 A BR0316108 A BR 0316108A BR 0316108 A BR0316108 A BR 0316108A BR 0316108 A BR0316108 A BR 0316108A
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- pyridylalkyl
- phenylalkyl
- piperazine derivatives
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurosurgery (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"DERIVADOS DE FENILALQUIL E PIRIDILALQUIL PIPERAZINA E COMPOSIçãO FARMACêUTICA COMPREENDENDO OS MESMOS". Esta invenção refere-se aos compostos da fórmula (1), em que R¬ 1¬, R¬ 3¬, R¬ 4¬, X¬ 1¬, e X¬ 2¬ são definidos como no relatório descritivo, às composições farmacêuticas que os contêm e ao seu uso no tratamento de distúrbios do sistema nervoso central e de outros distúrbios.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US42521902P | 2002-11-08 | 2002-11-08 | |
PCT/IB2003/004805 WO2004041793A1 (en) | 2002-11-08 | 2003-10-27 | Phenylalkyl and pyridylalkyl piperazine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0316108A true BR0316108A (pt) | 2005-09-27 |
Family
ID=32312946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0316108-0A BR0316108A (pt) | 2002-11-08 | 2003-10-27 | Derivados de fenilalquil e piridilalquil piperazina e composição farmacêutica compreendendo os mesmos |
Country Status (8)
Country | Link |
---|---|
US (1) | US7101886B2 (pt) |
EP (1) | EP1562919A1 (pt) |
JP (1) | JP2006508101A (pt) |
AU (1) | AU2003272030A1 (pt) |
BR (1) | BR0316108A (pt) |
CA (1) | CA2505397A1 (pt) |
MX (1) | MXPA05004273A (pt) |
WO (1) | WO2004041793A1 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000032987A (ja) * | 1998-07-16 | 2000-02-02 | Dai Ichi Seiyaku Co Ltd | Dna |
AU2002253342B2 (en) * | 2001-04-30 | 2007-01-04 | Glaxo Group Limited | Novel anti-inflammatory androstane derivatives |
GB0308025D0 (en) * | 2003-04-07 | 2003-05-14 | Glaxo Group Ltd | Compounds |
GB0316915D0 (en) | 2003-07-18 | 2003-08-20 | Glaxo Group Ltd | Compounds |
WO2008054748A2 (en) * | 2006-10-31 | 2008-05-08 | Arena Pharmaceuticals, Inc. | Indazole derivatives as modulators of the 5-ht2a serotonin receptor useful for the treatment of disorders related thereto |
EP2139460A4 (en) * | 2007-03-20 | 2011-09-07 | Univ Brandeis | COMPOSITIONS AND METHODS FOR THE DIAGNOSIS, TREATMENT AND PREVENTION OF AMYOTROPHER LATERAL SCLEROSIS AND ASSOCIATED NEUROLOGICAL DISEASES |
BRPI0918949A2 (pt) * | 2008-09-22 | 2019-09-24 | Hoffmann La Roche | moduladores de receptores de 5-ht2a e piperazina d3 |
CA2740952C (en) | 2008-10-22 | 2015-12-29 | Ian L. Scott | Compounds for treating ophthalmic diseases and disorders |
CN103130737B (zh) * | 2011-12-05 | 2015-12-02 | 江苏恒谊药业有限公司 | 环己烷胺类化合物及其作为抗精神分裂症药物的应用 |
CN104140421B (zh) * | 2013-05-08 | 2017-04-05 | 上海医药工业研究院 | 苯并异噻唑类化合物及在制备抗精神分裂症药物中的应用 |
KR102445983B1 (ko) | 2014-05-28 | 2022-09-21 | 바이엘 크롭사이언스 악티엔게젤샤프트 | 티아졸 유도체의 제조방법 |
GB201417168D0 (en) * | 2014-09-29 | 2014-11-12 | Univ Hertfordshire Higher Education Corp | Compounds |
TW202136235A (zh) | 2019-12-24 | 2021-10-01 | 日商大日本住友製藥股份有限公司 | 脂肪族酸醯胺衍生物 |
WO2023144764A1 (en) | 2022-01-29 | 2023-08-03 | Suven Life Sciences Limited | Benzoisothiazole and benzoisoxazole compounds for the treatment of mental disorders |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4184163A (en) * | 1976-11-29 | 1980-01-15 | Rca Corporation | Broad band, four loop antenna |
US4411901A (en) * | 1981-12-23 | 1983-10-25 | Mead Johnson & Company | Benzisothiazole and benzisoxazole piperazine derivatives |
US4554549A (en) * | 1983-09-19 | 1985-11-19 | Raytheon Company | Microstrip antenna with circular ring |
ATE126512T1 (de) * | 1989-05-19 | 1995-09-15 | Hoechst Roussel Pharma | N-(aryloxyalkyl)heteroarylpiperidine und - heteroarylpiperazine, verfahren zu ihrer herstellung und ihre verwendung als medikamente. |
US5350747A (en) * | 1989-07-07 | 1994-09-27 | Pfizer Inc | Heteroaryl piperazine antipsychotic agents |
FR2671350A1 (fr) * | 1991-01-08 | 1992-07-10 | Adir | Nouveaux derives de benzisoxazole et de benzisothiazole, leur procede de preparation, et les compositions pharmaceutiques les renfermant. |
AU645681B2 (en) * | 1991-05-02 | 1994-01-20 | John Wyeth & Brother Limited | Piperazine derivatives |
NZ240863A (en) * | 1991-09-11 | 1995-04-27 | Mcneilab Inc | Substituted 4-aryl piperidine and 4-aryl piperazine derivatives, preparation and pharmaceutical compositions thereof |
US5206366A (en) * | 1992-08-26 | 1993-04-27 | Pfizer Inc. | Process for preparing aryl piperazinyl-heterocyclic compounds |
RS20050195A (en) * | 2002-09-17 | 2007-08-03 | Warner Lambert Company Llc., | Heterocyclic substituted piperazines for the treatment of schizophrenia |
AU2003260882A1 (en) * | 2002-09-26 | 2004-04-19 | Warner-Lambert Company Llc | Heterocyclic substituted piperazines for the treatment of schizophrenia |
-
2003
- 2003-10-27 EP EP03753871A patent/EP1562919A1/en not_active Withdrawn
- 2003-10-27 MX MXPA05004273A patent/MXPA05004273A/es unknown
- 2003-10-27 AU AU2003272030A patent/AU2003272030A1/en not_active Abandoned
- 2003-10-27 WO PCT/IB2003/004805 patent/WO2004041793A1/en active Application Filing
- 2003-10-27 BR BR0316108-0A patent/BR0316108A/pt not_active IP Right Cessation
- 2003-10-27 CA CA002505397A patent/CA2505397A1/en not_active Abandoned
- 2003-10-27 JP JP2004549456A patent/JP2006508101A/ja not_active Withdrawn
- 2003-11-07 US US10/703,333 patent/US7101886B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1562919A1 (en) | 2005-08-17 |
WO2004041793A1 (en) | 2004-05-21 |
JP2006508101A (ja) | 2006-03-09 |
MXPA05004273A (es) | 2005-10-18 |
AU2003272030A1 (en) | 2004-06-07 |
CA2505397A1 (en) | 2004-05-21 |
US7101886B2 (en) | 2006-09-05 |
US20040186108A1 (en) | 2004-09-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0510453A (pt) | composto substituìdos com morfolina para o tratamento de distúrbios do sistema nervoso central | |
BR0314393A (pt) | Piperazinas heterocìclicas substituìdas para o tratamento de esquizofrenia | |
BRPI0413860A (pt) | [1,8]naftiridin-2-onas e compostos relacionados para o tratamento de esquizofrenia | |
BR9907270A (pt) | Composto, composição farmacêutica, uso de um composto, e, processos para tratamento ou profilaxia de doenças inflamatórias, por exemplo, asma ou copd, e para a preparação de um composto | |
BR9911482A (pt) | Composto, composição farmacêutica, uso do composto, e, processos para o tratamento ou profilaxia de doenças inflamatórias, e para a preparação de um composto | |
BRPI0607927A2 (pt) | derivados de pirazol-pirimidina | |
BR9811555A (pt) | 2-aminopiridinas contendo anéis substituintes fundidos como inibidores nos | |
BRPI0517423A (pt) | composto, composição farmacêutica, método para o tratamento ou prevenção de distúrbios neurológicos e psiquiátricos associados com disfunção do glutamato em um animal, e, uso em um composto | |
BR0312560A (pt) | Novas espiropiperidinas ou espiropirrolidinas tricìclicas | |
BR0315912A (pt) | Compostos pirimìdicos com atividade antiproliferativa (ii) | |
BR0316108A (pt) | Derivados de fenilalquil e piridilalquil piperazina e composição farmacêutica compreendendo os mesmos | |
BR0312464A (pt) | Inibidores de tirosina quinases | |
BRPI0719195B8 (pt) | inibidores de quinase, seus usos, e composição farmacêutica | |
BR0211284A (pt) | Derivados de 1-fenilsulfonil-1,3-dihidro-2h-indol-2-ona, a respectiva preparação e a respectiva aplicação em terapêutica | |
BR9911013A (pt) | Derivados de pirazol como inibidores da p-38 map quinase | |
BRPI0606107A2 (pt) | compostos farmacêuticos, seus proocessos de preparação, usos dos mesmos na fabricação de medicamento e composição farmacêutica compreendendo os referidos compostos | |
BR0313041A (pt) | Compostos; composições farmacêuticas; método para o tratamento e/ou profilaxia de doenças que estão associadas à modulação dos receptores de cb1; e uso de compostos | |
BRPI0413094A (pt) | derivados de quinolina e seu uso em terapia | |
BRPI0512986A (pt) | novos derivados de hidantoìna | |
EA201000436A1 (ru) | Стероидные [3,2-с]пиразольные соединения, обладающие глюкокортикоидной активностью | |
BRPI0407253A (pt) | Heterociclil-3-sulfonilindazóis como ligandos 5-hidroxitriptamina-6 processo de preparação dos mesmos, seus usos na preparação de uma composição farmacêutica e composição farmacêutica compreendendo os referidos compostos | |
BRPI0418255A (pt) | derivados de piperazina e piperidina n-substituìdos | |
BR0211559A (pt) | Compostos, composições de ligantes tetracìclicos terapeuticamente úteis e seus usos | |
BRPI0414948A (pt) | derivados de pirazolo-e-imidazo pirimidina | |
BR0012610A (pt) | Novo derivado de difenilpiperidina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE 5A., 6A, E 7A. ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2073 DE 28/09/2010. |