BR0314937A - Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso - Google Patents

Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso

Info

Publication number
BR0314937A
BR0314937A BR0314937-4A BR0314937A BR0314937A BR 0314937 A BR0314937 A BR 0314937A BR 0314937 A BR0314937 A BR 0314937A BR 0314937 A BR0314937 A BR 0314937A
Authority
BR
Brazil
Prior art keywords
intracellular pathogens
immunogenic compositions
recombinant
methods
attenuated
Prior art date
Application number
BR0314937-4A
Other languages
English (en)
Portuguese (pt)
Inventor
Marcus A Horwitz
Gunter Harth
Michael V Tullius
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/261,981 external-priority patent/US20030124135A1/en
Application filed by Univ California filed Critical Univ California
Publication of BR0314937A publication Critical patent/BR0314937A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR0314937-4A 2002-09-30 2003-09-30 Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso BR0314937A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/261,981 US20030124135A1 (en) 2000-04-17 2002-09-30 Recombinant intracellular pathogen vaccines and methods for use
US10/439,611 US6924118B2 (en) 2000-04-17 2003-05-15 Recombinant intracellular pathogen immunogenic compositions and methods for use
PCT/US2003/030994 WO2004031356A2 (en) 2002-09-30 2003-09-30 Recombinant intracellular pathogen immunogenic compositions and methods for use

Publications (1)

Publication Number Publication Date
BR0314937A true BR0314937A (pt) 2005-08-02

Family

ID=32072849

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314937-4A BR0314937A (pt) 2002-09-30 2003-09-30 Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso

Country Status (13)

Country Link
US (1) US6924118B2 (https=)
EP (1) EP1556081B1 (https=)
JP (1) JP2006501304A (https=)
KR (1) KR101066951B1 (https=)
CN (1) CN1703238B (https=)
AT (1) ATE487489T1 (https=)
AU (1) AU2003272808B2 (https=)
BR (1) BR0314937A (https=)
CA (1) CA2500433A1 (https=)
MX (1) MXPA05003407A (https=)
RU (1) RU2337707C2 (https=)
WO (1) WO2004031356A2 (https=)
ZA (1) ZA200502596B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6924118B2 (en) 2000-04-17 2005-08-02 The Regents Of The University Of California Recombinant intracellular pathogen immunogenic compositions and methods for use
WO2007121194A1 (en) * 2006-04-10 2007-10-25 The Regents Of The University Of California Immunostimulatory recombinant intracellular pathogen immunogenic compositions and methods of use
US8383132B2 (en) * 2003-10-16 2013-02-26 The Regents Of The University Of California Immunostimulatory recombinant intracellular pathogen immunogenic compositions and methods of use
US8163294B2 (en) * 2003-10-16 2012-04-24 The Regents Of The University Of California Growth regulatable recombinant BCG compositions
US7622107B2 (en) 2003-10-16 2009-11-24 The Regents Of The University Of California Recombinant intracellular pathogen immunogenic compositions and methods for use
CN101198358B (zh) * 2004-12-01 2013-06-26 Aeras全球Tb疫苗基金会 具有增强的逃出内体能力的重组bcg菌株
CN107092614B (zh) 2010-08-09 2021-04-20 Sk 普兰尼特有限公司 集成图像搜索终端、设备及其服务方法
RU2517218C1 (ru) * 2012-10-25 2014-05-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Способ моделирования гиперчувствительности замедленного типа у морских свинок на микобактерии m.bovis
CN113999865B (zh) * 2021-10-09 2023-06-16 安徽理工大学 结核分枝杆菌融合蛋白ar2及其构建与表达纯化方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591632A (en) 1987-03-02 1997-01-07 Beth Israel Hospital Recombinant BCG
ATE132195T1 (de) 1987-03-02 1996-01-15 Whitehead Biomedical Inst Rekombinant-mykobakterielle impfstoffe
US5807723A (en) 1987-03-02 1998-09-15 Whitehead Institute For Biomedical Research Homologously recombinant slow growing mycobacteria and uses therefor
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
JP2903414B2 (ja) 1989-05-31 1999-06-07 味の素株式会社 抗酸菌分泌発現ベクター及び抗酸菌
WO1993007897A1 (en) 1991-10-21 1993-04-29 Medimmune, Inc. Bacterial expression vectors containing dna encoding secretion signals of lipoproteins
US5736367A (en) 1992-03-31 1998-04-07 Medimmune, Inc. Vectors and prokaryotes which autocatalytically delete antibiotic resistance
US5679515A (en) 1994-10-03 1997-10-21 Pathogenesis Corporation Mycobacterial reporter strains and uses thereof
US5700683A (en) 1995-02-17 1997-12-23 Pathogenesis Corporation Virulence-attenuating genetic deletions deleted from mycobacterium BCG
US5869057A (en) 1995-06-07 1999-02-09 Rock; Edwin P. Recombinant vaccines to break self-tolerance
RU2112543C1 (ru) * 1996-09-26 1998-06-10 Александр Григорьевич Хоменко Иммуномодулирующее лекарственное средство
US6924118B2 (en) 2000-04-17 2005-08-02 The Regents Of The University Of California Recombinant intracellular pathogen immunogenic compositions and methods for use
US6471967B1 (en) * 2000-04-17 2002-10-29 The Regents Of The University Of California Recombinant intracellular pathogen vaccines and methods for use

Also Published As

Publication number Publication date
US6924118B2 (en) 2005-08-02
CA2500433A1 (en) 2004-04-15
EP1556081A2 (en) 2005-07-27
US20040009184A1 (en) 2004-01-15
WO2004031356A3 (en) 2004-08-26
AU2003272808B2 (en) 2010-01-21
JP2006501304A (ja) 2006-01-12
CN1703238B (zh) 2012-05-30
KR101066951B1 (ko) 2011-09-23
AU2003272808A1 (en) 2004-04-23
ZA200502596B (en) 2005-12-28
RU2005113266A (ru) 2006-01-20
RU2337707C2 (ru) 2008-11-10
KR20050075343A (ko) 2005-07-20
WO2004031356A2 (en) 2004-04-15
CN1703238A (zh) 2005-11-30
EP1556081A4 (en) 2006-10-25
ATE487489T1 (de) 2010-11-15
EP1556081B1 (en) 2010-11-10
MXPA05003407A (es) 2005-08-02

Similar Documents

Publication Publication Date Title
MX2022015040A (es) Proteina espicular (s) del coronavirus geneticamente manipulada y metodos de uso de la misma.
WO2005037222A3 (en) Recombinant intracellular pathogen immunogenic compositions and methods for use
DK1326633T3 (da) Sammensætning omfattende immunogene mikropartikler
DE602004028468D1 (de) Haltung von immunantworten gegen mhc-klasse-i-beschränkte epitope, für prophylaktische oder therapeutische zwecke
IL184845A0 (en) Chimeric recombinant antigens of toxoplasma gondii
ECSP066379A (es) Anticuerpos rg1 y usos de los mismos
MX2008013993A (es) Combinación adyuvante sinergistica de anticuerpo agonista de cd40/interferona tipo 1, conjugados que la contienen y uso de los mismos como un terapeutico para aumentar la inmunidad celular.
BR0306665A (pt) Uso de zeìna nativa para aperfeiçoamento do estado do cabelo e agentes
DK2054431T3 (da) Konformere af bakterielle adhæsiner
BR0211761A (pt) depsipeptìdeos e processos para preparar os mesmos
BR0314937A (pt) Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso
ATE551069T1 (de) Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung
DE602004028029D1 (en) Rwendung
WO2019094533A8 (en) Angptl8-binding agents and methods of use thereof
DK1290160T3 (da) Humane Pellino-polypeptider
BR0207528A (pt) Anticorpo, composição farmacêutica, e, usos de uma quantidade efetiva de um agente, de uma quantidade terapeuticamente efetiva de um anticorpo para il-22, de uma quantidade imunogênica do antìgeno e uma quantidade aumentadora de imunogenicidade de il-22 em combinação, de uma quantidade efetiva do anticorpo ou fragmento do mesmo e de uma quantidade suficiente de anticorpo ou fragmento ligado a antìgeno do mesmo
ATE404218T1 (de) Rekombinante bcg-impfstoffe gegen intrazelluläre pathogene und anwendungsverfahren
EA200600439A1 (ru) 4- ((феноксиалкил)тио) феноксиуксусные кислоты и аналоги
JOP20240233A1 (ar) بروتينات cd24 الطافرة واستخداماتها للوقاية من السرطان وعلاجه
DE50212580D1 (de) Rekombinantes mva mit der fähigkeit zur expression von hcv struktur-antigenen
DE602004015141D1 (de) Modifizierte ganzzell-, zellextrakt- und omv-basierte impfstoffe
MX2009011851A (es) Plasmidos de dna que tienen expresion y estabilidad mejoradas.
BR0212289A (pt) Anticorpos contra caspase-8, preparação e uso do mesmo
ATE353226T1 (de) Adjuvanszusammensetzung enthaltend fha oder ein fha-fragment in freier form
DE60210936D1 (de) Polypeptid, das neutralisierende antikörper gegen hiv induziert

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL