BR0314937A - Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso - Google Patents

Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso

Info

Publication number
BR0314937A
BR0314937A BR0314937-4A BR0314937A BR0314937A BR 0314937 A BR0314937 A BR 0314937A BR 0314937 A BR0314937 A BR 0314937A BR 0314937 A BR0314937 A BR 0314937A
Authority
BR
Brazil
Prior art keywords
intracellular pathogens
immunogenic compositions
recombinant
methods
attenuated
Prior art date
Application number
BR0314937-4A
Other languages
English (en)
Portuguese (pt)
Inventor
Marcus A Horwitz
Gunter Harth
Michael V Tullius
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/261,981 external-priority patent/US20030124135A1/en
Application filed by Univ California filed Critical Univ California
Publication of BR0314937A publication Critical patent/BR0314937A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BR0314937-4A 2002-09-30 2003-09-30 Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso BR0314937A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/261,981 US20030124135A1 (en) 2000-04-17 2002-09-30 Recombinant intracellular pathogen vaccines and methods for use
US10/439,611 US6924118B2 (en) 2000-04-17 2003-05-15 Recombinant intracellular pathogen immunogenic compositions and methods for use
PCT/US2003/030994 WO2004031356A2 (en) 2002-09-30 2003-09-30 Recombinant intracellular pathogen immunogenic compositions and methods for use

Publications (1)

Publication Number Publication Date
BR0314937A true BR0314937A (pt) 2005-08-02

Family

ID=32072849

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314937-4A BR0314937A (pt) 2002-09-30 2003-09-30 Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso

Country Status (13)

Country Link
US (1) US6924118B2 (enExample)
EP (1) EP1556081B1 (enExample)
JP (1) JP2006501304A (enExample)
KR (1) KR101066951B1 (enExample)
CN (1) CN1703238B (enExample)
AT (1) ATE487489T1 (enExample)
AU (1) AU2003272808B2 (enExample)
BR (1) BR0314937A (enExample)
CA (1) CA2500433A1 (enExample)
MX (1) MXPA05003407A (enExample)
RU (1) RU2337707C2 (enExample)
WO (1) WO2004031356A2 (enExample)
ZA (1) ZA200502596B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6924118B2 (en) 2000-04-17 2005-08-02 The Regents Of The University Of California Recombinant intracellular pathogen immunogenic compositions and methods for use
EP2206514B1 (en) * 2003-10-16 2014-01-08 The Regents of The University of California Recombinant intracellular pathogen immunogenic compositions and methods for use
US8383132B2 (en) * 2003-10-16 2013-02-26 The Regents Of The University Of California Immunostimulatory recombinant intracellular pathogen immunogenic compositions and methods of use
US8163294B2 (en) * 2003-10-16 2012-04-24 The Regents Of The University Of California Growth regulatable recombinant BCG compositions
WO2007121194A1 (en) * 2006-04-10 2007-10-25 The Regents Of The University Of California Immunostimulatory recombinant intracellular pathogen immunogenic compositions and methods of use
AP2007004033A0 (en) * 2004-12-01 2007-06-30 Aeras Global Tb Baccine Founda Recombinant bcg strains with enhanced ability to escape the endosome
WO2012020927A1 (ko) 2010-08-09 2012-02-16 에스케이텔레콤 주식회사 통합 영상 검색 시스템 및 그 서비스 방법
RU2517218C1 (ru) * 2012-10-25 2014-05-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Способ моделирования гиперчувствительности замедленного типа у морских свинок на микобактерии m.bovis
CN113999865B (zh) * 2021-10-09 2023-06-16 安徽理工大学 结核分枝杆菌融合蛋白ar2及其构建与表达纯化方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807723A (en) 1987-03-02 1998-09-15 Whitehead Institute For Biomedical Research Homologously recombinant slow growing mycobacteria and uses therefor
JP3011939B2 (ja) 1987-03-02 2000-02-21 ホワイトヘツド・インスチチユート・フオー・バイオメデイカル・リサーチ 組換えミコバクテリア・ワクチン
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
US5591632A (en) 1987-03-02 1997-01-07 Beth Israel Hospital Recombinant BCG
JP2903414B2 (ja) 1989-05-31 1999-06-07 味の素株式会社 抗酸菌分泌発現ベクター及び抗酸菌
AU681572B2 (en) 1991-10-21 1997-09-04 Med Immune, Inc. Bacterial expression vectors containing DNA encoding secretion signals of lipoproteins
US5736367A (en) 1992-03-31 1998-04-07 Medimmune, Inc. Vectors and prokaryotes which autocatalytically delete antibiotic resistance
US5679515A (en) 1994-10-03 1997-10-21 Pathogenesis Corporation Mycobacterial reporter strains and uses thereof
US5700683A (en) 1995-02-17 1997-12-23 Pathogenesis Corporation Virulence-attenuating genetic deletions deleted from mycobacterium BCG
US5869057A (en) 1995-06-07 1999-02-09 Rock; Edwin P. Recombinant vaccines to break self-tolerance
RU2112543C1 (ru) * 1996-09-26 1998-06-10 Александр Григорьевич Хоменко Иммуномодулирующее лекарственное средство
US6924118B2 (en) 2000-04-17 2005-08-02 The Regents Of The University Of California Recombinant intracellular pathogen immunogenic compositions and methods for use
US6471967B1 (en) * 2000-04-17 2002-10-29 The Regents Of The University Of California Recombinant intracellular pathogen vaccines and methods for use

Also Published As

Publication number Publication date
US6924118B2 (en) 2005-08-02
CA2500433A1 (en) 2004-04-15
KR20050075343A (ko) 2005-07-20
MXPA05003407A (es) 2005-08-02
AU2003272808A1 (en) 2004-04-23
EP1556081A2 (en) 2005-07-27
WO2004031356A3 (en) 2004-08-26
CN1703238B (zh) 2012-05-30
ZA200502596B (en) 2005-12-28
EP1556081A4 (en) 2006-10-25
RU2005113266A (ru) 2006-01-20
US20040009184A1 (en) 2004-01-15
KR101066951B1 (ko) 2011-09-23
WO2004031356A2 (en) 2004-04-15
ATE487489T1 (de) 2010-11-15
JP2006501304A (ja) 2006-01-12
RU2337707C2 (ru) 2008-11-10
EP1556081B1 (en) 2010-11-10
AU2003272808B2 (en) 2010-01-21
CN1703238A (zh) 2005-11-30

Similar Documents

Publication Publication Date Title
MX2022015040A (es) Proteina espicular (s) del coronavirus geneticamente manipulada y metodos de uso de la misma.
DK1326633T3 (da) Sammensætning omfattende immunogene mikropartikler
BR0208076A (pt) Células t cd4*cd25* reguladoras de sangue humano
IL184845A0 (en) Chimeric recombinant antigens of toxoplasma gondii
ECSP066379A (es) Anticuerpos rg1 y usos de los mismos
WO2005037222A3 (en) Recombinant intracellular pathogen immunogenic compositions and methods for use
CR8257A (es) Construcciones de union y metodos para uso de ellas
CY1111622T1 (el) Ανθρωποποιημενοι ανταγωνιστες anti-cmet
WO2007024941A3 (en) Polyvalent vaccine
DK2054431T3 (da) Konformere af bakterielle adhæsiner
BR0314937A (pt) Composições imunogênicas de patógenos intracelulares recombinantes e métodos para uso
ATE551069T1 (de) Mucin-fusionspolypeptid-vakzine, zusammensetzungen und ihre verwendung
ATE473236T1 (de) Antigene von piscirickettsia salmonis und deren verwendung
WO2019094533A8 (en) Angptl8-binding agents and methods of use thereof
ATE404218T1 (de) Rekombinante bcg-impfstoffe gegen intrazelluläre pathogene und anwendungsverfahren
WO2007078879A3 (en) Lipopeptide compositions and methods of use thereof
ATE403007T1 (de) Rekombinantes mva mit der fähigkeit zur expression von hcv struktur-antigenen
WO2019210282A3 (en) Mycobacterial antigen compositions and methods of use
DE602004015141D1 (de) Modifizierte ganzzell-, zellextrakt- und omv-basierte impfstoffe
BR0212289A (pt) Anticorpos contra caspase-8, preparação e uso do mesmo
ATE353226T1 (de) Adjuvanszusammensetzung enthaltend fha oder ein fha-fragment in freier form
DE60113535D1 (de) Kompositionen und verwendungen von cgi-69
MX2009011851A (es) Plasmidos de dna que tienen expresion y estabilidad mejoradas.
DE602005020147D1 (de) Detektion von verkürzungsmutationen durch massenspektrometrie
MX2025007937A (es) Proteinas 3 f del virus de la parainfluenza humana estabilizadas prefusion

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL