BR0312896A - Glicanos e glicopeptìdeos de campylobacter - Google Patents
Glicanos e glicopeptìdeos de campylobacterInfo
- Publication number
- BR0312896A BR0312896A BR0312896-2A BR0312896A BR0312896A BR 0312896 A BR0312896 A BR 0312896A BR 0312896 A BR0312896 A BR 0312896A BR 0312896 A BR0312896 A BR 0312896A
- Authority
- BR
- Brazil
- Prior art keywords
- galnac
- glycan
- campylobacter
- bac
- antibodies
- Prior art date
Links
- 241000589876 Campylobacter Species 0.000 title abstract 3
- 102000002068 Glycopeptides Human genes 0.000 title abstract 3
- 108010015899 Glycopeptides Proteins 0.000 title abstract 3
- 150000004676 glycans Chemical class 0.000 abstract 5
- 206010051226 Campylobacter infection Diseases 0.000 abstract 2
- 102000003886 Glycoproteins Human genes 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical compound NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 abstract 1
- 238000005004 MAS NMR spectroscopy Methods 0.000 abstract 1
- 238000005481 NMR spectroscopy Methods 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- NRXWTRNYICXMBF-CACQUXPASA-N n-[(2r,3s,4s,5r)-5-acetamido-4,6-dihydroxy-2-methyloxan-3-yl]acetamide Chemical compound C[C@H]1OC(O)[C@H](NC(C)=O)[C@@H](O)[C@@H]1NC(C)=O NRXWTRNYICXMBF-CACQUXPASA-N 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 230000001717 pathogenic effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56922—Campylobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
- G01N2400/02—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Virology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Fodder In General (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39973502P | 2002-08-01 | 2002-08-01 | |
| PCT/CA2003/001156 WO2004013151A2 (en) | 2002-08-01 | 2003-07-30 | Campylobacter glycans and glycopeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0312896A true BR0312896A (pt) | 2005-06-14 |
Family
ID=31495764
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0312896-2A BR0312896A (pt) | 2002-08-01 | 2003-07-30 | Glicanos e glicopeptìdeos de campylobacter |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7598354B2 (https=) |
| EP (1) | EP1527080B1 (https=) |
| JP (1) | JP4718174B2 (https=) |
| CN (1) | CN1671722A (https=) |
| AU (1) | AU2003254665C1 (https=) |
| BR (1) | BR0312896A (https=) |
| CA (1) | CA2494223C (https=) |
| ES (1) | ES2391525T3 (https=) |
| WO (1) | WO2004013151A2 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
| US7214660B2 (en) * | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
| IL163806A0 (en) | 2002-03-07 | 2005-12-18 | Eidgenoess Tech Hochschule | System and method for the production of recombinant glycosylated proteins in a prokaryotic host |
| AU2002952121A0 (en) * | 2002-10-17 | 2002-10-31 | Alchemia Limited | Novel carbohydrate based anti-bacterials |
| PL1615945T3 (pl) | 2003-04-09 | 2012-03-30 | Ratiopharm Gmbh | Sposoby glikopegylacji i białka/peptydy wytwarzane tymi sposobami |
| US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
| US8633157B2 (en) | 2003-11-24 | 2014-01-21 | Novo Nordisk A/S | Glycopegylated erythropoietin |
| JP2007515410A (ja) * | 2003-12-03 | 2007-06-14 | ネオス テクノロジーズ インコーポレイテッド | ＧｌｙｃｏＰＥＧ化卵胞刺激ホルモン |
| US20080300173A1 (en) | 2004-07-13 | 2008-12-04 | Defrees Shawn | Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1] |
| WO2006050247A2 (en) | 2004-10-29 | 2006-05-11 | Neose Technologies, Inc. | Remodeling and glycopegylation of fibroblast growth factor (fgf) |
| US9029331B2 (en) | 2005-01-10 | 2015-05-12 | Novo Nordisk A/S | Glycopegylated granulocyte colony stimulating factor |
| WO2006121569A2 (en) | 2005-04-08 | 2006-11-16 | Neose Technologies, Inc. | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
| ES2353814T3 (es) * | 2005-05-11 | 2011-03-07 | Eth Zuerich | Proteinas n-glicosiladas recombinantes de celulas procariotas. |
| US20070105755A1 (en) * | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
| WO2007056191A2 (en) | 2005-11-03 | 2007-05-18 | Neose Technologies, Inc. | Nucleotide sugar purification using membranes |
| EP2049144B8 (en) | 2006-07-21 | 2015-02-18 | ratiopharm GmbH | Glycosylation of peptides via o-linked glycosylation sequences |
| EP2054521A4 (en) | 2006-10-03 | 2012-12-19 | Novo Nordisk As | PROCESS FOR CLEANING POLYPEPTIDE CONJUGATES |
| HRP20130382T1 (hr) | 2007-04-03 | 2013-05-31 | Biogenerix Ag | Postupci lijeäśenja pomoä†u glikopegiliranog g-csf |
| CA2690611C (en) | 2007-06-12 | 2015-12-08 | Novo Nordisk A/S | Improved process for the production of nucleotide sugars |
| CN107119095B (zh) | 2008-01-03 | 2022-07-05 | 康乃尔研究基金会有限公司 | 原核生物中的糖基化蛋白表达 |
| CA2711503A1 (en) * | 2008-01-08 | 2009-07-16 | Biogenerix Ag | Glycoconjugation of polypeptides using oligosaccharyltransferases |
| CN101983070B (zh) | 2008-02-20 | 2016-03-30 | 格林考瓦因有限公司 | 由来源于原核细胞的重组n-糖基化蛋白制备生物共轭物 |
| PL2257311T3 (pl) | 2008-02-27 | 2014-09-30 | Novo Nordisk As | Koniugaty cząsteczek czynnika VIII |
| PL2411503T3 (pl) * | 2009-03-27 | 2018-01-31 | Eidgenoessische Technische Hochschule Zuerich | Salmonella enterica prezentująca n-glikan z c. jejuni lub jego pochodne |
| NO2501406T3 (https=) | 2009-11-19 | 2018-05-19 | ||
| PT2545081E (pt) * | 2010-02-11 | 2015-05-18 | Univ Alberta | Compostos de glicano ligados por n |
| US8841099B2 (en) * | 2010-04-20 | 2014-09-23 | National Research Council Of Canada | Cell-based production of nonulosonates |
| EP3281639B1 (en) | 2010-05-06 | 2020-11-11 | GlaxoSmithKline Biologicals S.A. | Capsular gram-positive bacteria bioconjugate vaccines |
| US9308246B2 (en) | 2010-05-28 | 2016-04-12 | The United States Of America As Represented By The Secretary Of The Navy | Capsule composition for use as immunogen against Campylobacter jejuni |
| JP6135046B2 (ja) * | 2012-04-20 | 2017-05-31 | 株式会社島津製作所 | 糖ペプチドの質量分析法 |
| RU2671473C2 (ru) | 2013-04-05 | 2018-10-31 | Де Гавенерс Оф Де Юниверсити Оф Альберта | Вакцина против кампилобактериоза |
| HK1246600B (en) * | 2015-01-26 | 2020-04-09 | Cadena Bio, Inc. | Oligosaccharide compositions for use animal feed and methods of producing thereof |
| WO2017117539A1 (en) | 2015-12-30 | 2017-07-06 | Northwestern University | Cell-free glycoprotein synthesis (cfgps) in prokaryotic cell lysates enriched with components for glycosylation |
| US10829795B2 (en) | 2016-07-14 | 2020-11-10 | Northwestern University | Method for rapid in vitro synthesis of glycoproteins via recombinant production of N-glycosylated proteins in prokaryotic cell lysates |
| WO2019035916A1 (en) | 2017-08-15 | 2019-02-21 | Northwestern University | DESIGN OF PROTEIN GLYCOSYLATION SITES BY RAPID EXPRESSION AND CHARACTERIZATION OF N-GLYCOSYLTRANSFERASES |
| EP3727437A4 (en) * | 2017-12-19 | 2021-09-08 | The Governors of the University of Alberta | SURFACE GLYCANES OF CLOSTRIDIUM PERFRINGENS AND ASSOCIATED USES |
| US11530432B2 (en) | 2018-03-19 | 2022-12-20 | Northwestern University | Compositions and methods for rapid in vitro synthesis of bioconjugate vaccines in vitro via production and N-glycosylation of protein carriers in detoxified prokaryotic cell lysates |
| WO2019204346A1 (en) | 2018-04-16 | 2019-10-24 | Northwestern University | METHODS FOR CO-ACTIVATING IN VITRO NON-STANDARD AMINO ACID (nsAA) INCORPORATION AND GLYCOSYLATION IN CRUDE CELLLYSATES |
| US12098433B2 (en) | 2018-08-03 | 2024-09-24 | Northwestern University | On demand, portable, cell-free molecular sensing platform |
| CN113646438A (zh) | 2019-01-11 | 2021-11-12 | 西北大学 | 在原核生物细胞裂解物中合成生物缀合物疫苗 |
| US12325884B2 (en) | 2019-03-04 | 2025-06-10 | Northwestern University | Riboswitch-based fluoride sensing in cell-free extract |
| US12226410B2 (en) | 2019-10-18 | 2025-02-18 | Northwestern University | Methods for enhancing cellular clearance of pathological molecules via activation of the cellular protein ykt6 |
| CN115135771A (zh) | 2019-10-25 | 2022-09-30 | 西北大学 | 用于富集膜泡和增加糖蛋白产量的无细胞提取物制备方案 |
| WO2022256920A1 (en) * | 2021-06-07 | 2022-12-15 | The University Of British Columbia | Acholetin biopolymers and methods for enzymatic synthesis |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4925796A (en) * | 1986-03-07 | 1990-05-15 | Massachusetts Institute Of Technology | Method for enhancing glycoprotein stability |
| US5200344A (en) * | 1990-11-13 | 1993-04-06 | Blaser Martin J | Diagnostic testing for campylobacter jejuni or campylobacter coli infections using novel antigens |
| JPH09502604A (ja) * | 1993-08-27 | 1997-03-18 | エンテリック リサーチ ラボラトリーズ インコーポレイテッド | Ｃａｍｐｙｌｏｂａｃｔｅｒｊｅｊｕｎｉ抗原、並びにそれらの製造及び利用 |
| ATE195147T1 (de) * | 1994-09-06 | 2000-08-15 | Ab Bioflexin | Aminosäuren konjugaten |
| US5840547A (en) * | 1995-01-05 | 1998-11-24 | Ramot University Authority For Applied Research & Indfustrial Development Ltd. | Bioemulsifiers |
| US6676946B2 (en) * | 1997-03-27 | 2004-01-13 | Institut Pasteur | Multiple antigen glycopeptide carbohydrate vaccine comprising the same and use thereof |
| US6699705B2 (en) * | 1999-02-01 | 2004-03-02 | National Research Council Of Canada | Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics |
| AU3513500A (en) * | 1999-03-05 | 2000-09-21 | Trustees Of Tufts College | Emulsan and emulsan analogs immunization formulations and use |
| US6512014B2 (en) * | 2000-12-13 | 2003-01-28 | Ramot University Authority For Applied Research And Industrial Development Limited | Compositions containing bioemulsifiers and a method for their preparation |
| ES2411007T3 (es) * | 2001-10-10 | 2013-07-04 | Novo Nordisk A/S | Remodelación y glicoconjugación de péptidos |
| US20030232401A1 (en) * | 2002-06-12 | 2003-12-18 | Pugia Michael J. | Bacterial test method by glycated label binding |
| AU2006295017B2 (en) * | 2005-09-21 | 2010-06-17 | The United States Of America As Represented By The Secretary Of The Navy | Immunogenic capsule composition for use as a vaccine component against Campylobacter jejuni |
-
2003
- 2003-07-30 WO PCT/CA2003/001156 patent/WO2004013151A2/en not_active Ceased
- 2003-07-30 EP EP03766087A patent/EP1527080B1/en not_active Expired - Lifetime
- 2003-07-30 BR BR0312896-2A patent/BR0312896A/pt not_active IP Right Cessation
- 2003-07-30 ES ES03766087T patent/ES2391525T3/es not_active Expired - Lifetime
- 2003-07-30 CN CNA038181851A patent/CN1671722A/zh active Pending
- 2003-07-30 US US10/523,459 patent/US7598354B2/en not_active Expired - Lifetime
- 2003-07-30 AU AU2003254665A patent/AU2003254665C1/en not_active Expired
- 2003-07-30 JP JP2004525093A patent/JP4718174B2/ja not_active Expired - Fee Related
- 2003-07-30 CA CA2494223A patent/CA2494223C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2494223C (en) | 2012-10-02 |
| AU2003254665C1 (en) | 2010-08-19 |
| US7598354B2 (en) | 2009-10-06 |
| EP1527080B1 (en) | 2012-06-20 |
| EP1527080A2 (en) | 2005-05-04 |
| WO2004013151A3 (en) | 2004-07-01 |
| ES2391525T3 (es) | 2012-11-27 |
| CA2494223A1 (en) | 2004-02-12 |
| AU2003254665B2 (en) | 2010-01-28 |
| CN1671722A (zh) | 2005-09-21 |
| JP2005534752A (ja) | 2005-11-17 |
| US20060165728A1 (en) | 2006-07-27 |
| WO2004013151A2 (en) | 2004-02-12 |
| JP4718174B2 (ja) | 2011-07-06 |
| AU2003254665A1 (en) | 2004-02-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0312896A (pt) | Glicanos e glicopeptìdeos de campylobacter | |
| León-Sicairos et al. | Amoebicidal activity of milk, apo-lactoferrin, sIgA and lysozyme | |
| Hoyle | The influenza viruses | |
| Paba et al. | Proteomic analysis of the human pathogen Trypanosoma cruzi | |
| Goldsmit et al. | An improved method for the isolation and identification of bluetongue virus by intravenous inoculation of embryonating chicken eggs | |
| Zhai et al. | Enhanced immune responses of chickens to oral vaccination against infectious bursal disease by ginseng stem-leaf saponins | |
| BR9912178A (pt) | Vacinas de peptìdeo sintéticas para febre aftosa | |
| BR0012919A (pt) | Vacina para uso na profilaxia e/ou no tratamento da sìndrome de ponto branco (white spot syndrome) em crustáceos, proteìna estrutural derivada do vìrus da sìndrome de ponto branco, sequência de ácido nucléico, uso de uma proteìna estrutural, composição farmacêutica, anticorpos, vacina ou formulação farmacêutica, e, kit diagnóstico para detecção de wssv | |
| Bittar et al. | Effects of injectable trace minerals on the immune response to Mannheimia haemolytica and Pasteurella multocida following vaccination of dairy calves with a commercial attenuated-live bacterin vaccine | |
| ECSP024257A (es) | Proteinas antigenas del virus de la enfermedad de la mancha blanca en el camaron y usos de las mismas | |
| WO2021233885A1 (en) | Mimotope peptides of the spike protein from the sars-cov-2 virus | |
| Hajnicka et al. | Tick salivary gland extracts promote virus growth in vitro | |
| US20200069781A1 (en) | Immunogenic lhrh composition and use thereof in pigs | |
| Acosta et al. | Structural and immunological characterization of sulphatides: relevance of sulphate moieties in Trypanosoma cruzi glycoconjugates | |
| LEACH et al. | A pilot safety and immunogenicity study of the malaria vaccine SPf66 in Gambian infants | |
| Neurath et al. | Solubilization and some properties of the erythrocyte receptor for adenovirus type 7 haemagglutinin | |
| US20240218020A1 (en) | Peptides inhibiting covid-19 | |
| Ansari et al. | An experimental and clinical evaluation of immuno-modulating potential of human placental extract | |
| CN1341150A (zh) | 疟疾疫苗 | |
| US4083959A (en) | Therapeutical method for treating infection of mink hemorrhagic pneumonitis | |
| Qureshi et al. | A novel phage based marker vaccine and DI VA assay for hemorrhagic septicemia in bovines | |
| BR0001559A (pt) | Vacina para a prevenção da colonização de campylobacter em animais, proteìna antigênica de campylobacter, uso de uma proteìna antigênica, vacina para a prevenção da colonização de campylobacter jejuni em galináceos, uso de anticorpos contra uma cepa de campylobacter sem flagelos, ou contra a proteìna antigênica, e, processo para a preparação de uma vacina | |
| Peter et al. | Detection of bovine viral diarrhea virus antibodies in camels (Camelus dromedarius) in Maiduguri, Nigeria | |
| BRPI0503187B1 (pt) | Composição compreendendo fucose manose ligand (fml) e saponina, para uso como uma vacina bloqueadora contra a transmissão de leishmaniose visceral canina | |
| Trybala et al. | An Intradermal Test for the Diagnosis of BHV‐1 Infection. The Effect of Repeated Testing on the Immune Status of Cattle |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2162 DE 12/06/2012. |