BR0308779A - Composição farmacêutica, e, método de preparação da mesma - Google Patents

Composição farmacêutica, e, método de preparação da mesma

Info

Publication number
BR0308779A
BR0308779A BR0308779-4A BR0308779A BR0308779A BR 0308779 A BR0308779 A BR 0308779A BR 0308779 A BR0308779 A BR 0308779A BR 0308779 A BR0308779 A BR 0308779A
Authority
BR
Brazil
Prior art keywords
sugar
pharmaceutical composition
mixture
glass
preparation
Prior art date
Application number
BR0308779-4A
Other languages
English (en)
Inventor
Anko C Eissens
Dirk J Van Drooge
Wouter L J Hinrichs
Henderik W Frijlink
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Publication of BR0308779A publication Critical patent/BR0308779A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"COMPOSIçãO FARMACêUTICA, E, MéTODO DE PREPARAçãO DA MESMA". A presente invenção é relacionada a uma composição farmacêutica que compreende um composto canabinóide natural, por exemplo o <30>^ 9^-tetraidrocanabinol, e um vidro de um açúcar, álcool de açúcar, mistura de açúcares ou mistura de álcoois de açúcar, caracterizada em que o composto canabinóide natural é incorporado no vidro de açúcar como uma encapsulação mononuclear sem a formação de um complexo de hóspede-hospedeiro. A invenção ainda diz respeito a um método para a preparação da referida composição farmacêutica na forma de um vidro de açucar mediante secagem de congelamento, secagem de pulverização, secagem em vácuo ou secagem crítica de uma mistura estável contendo o composto canabinóide natural e um açúcar ou mistura de açúcares.
BR0308779-4A 2002-04-03 2003-04-02 Composição farmacêutica, e, método de preparação da mesma BR0308779A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36961302P 2002-04-03 2002-04-03
EP02076339 2002-04-04
PCT/EP2003/050087 WO2003082246A1 (en) 2002-04-03 2003-04-02 Stabilized natural cannabinoid formulation

Publications (1)

Publication Number Publication Date
BR0308779A true BR0308779A (pt) 2004-12-28

Family

ID=28676390

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308779-4A BR0308779A (pt) 2002-04-03 2003-04-02 Composição farmacêutica, e, método de preparação da mesma

Country Status (17)

Country Link
EP (1) EP1492503B1 (pt)
JP (1) JP4491241B2 (pt)
CN (1) CN100592903C (pt)
AT (1) ATE413862T1 (pt)
AU (1) AU2003240759B2 (pt)
BR (1) BR0308779A (pt)
CA (1) CA2480270A1 (pt)
DE (1) DE60324668D1 (pt)
DK (1) DK1492503T3 (pt)
ES (1) ES2316759T3 (pt)
HK (1) HK1078458A1 (pt)
HR (1) HRP20040816A2 (pt)
MX (1) MXPA04009673A (pt)
NO (1) NO20044749L (pt)
PL (1) PL209134B1 (pt)
RU (1) RU2311178C2 (pt)
WO (1) WO2003082246A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1428526A1 (en) * 2002-12-13 2004-06-16 Rijksuniversiteit Groningen Formulation for fast dissolution of lipophilic compounds
DE10339197A1 (de) * 2003-08-22 2005-03-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Sprühgetrocknete amorphe Pulver mit geringer Restfeuchte und guter Lagerstabilität
TW200621310A (en) * 2004-11-10 2006-07-01 Univ Groningen A process for preparing formulations of lypophilic active substances by spray freeze drying
GB0523638D0 (en) * 2005-11-21 2005-12-28 Cambridge Biostability Ltd Pharmaceutical device for the administration of substances to patients
JO3112B1 (ar) 2010-03-29 2017-09-20 Ferring Bv تركيبة دوائية سريعة التحلل
PL2552418T3 (pl) 2010-03-29 2017-12-29 Ferring B.V. Szybko rozpuszczająca się kompozycja farmaceutyczna
WO2013037708A1 (en) 2011-09-16 2013-03-21 Ferring B.V. A fast dissolving pharmaceutical composition
US8741341B2 (en) * 2012-05-07 2014-06-03 Insys Therapeutics, Inc. Manufacturing and packaging room temperature stable dronabinol capsules
US10328216B2 (en) * 2016-01-20 2019-06-25 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispensible spray dried powders suitable for inhalation
US11833118B2 (en) 2016-01-20 2023-12-05 Flurry Powders, Llc Encapsulation of lipophilic ingredients in dispersible spray dried powders suitable for inhalation
WO2019211772A1 (en) * 2018-05-03 2019-11-07 Radient Technologies Inc. Obtaining extracts in a solid form
WO2020010454A1 (en) * 2018-07-10 2020-01-16 Beleave Inc. Formulation of cannabinoid compounds
CN110200953B (zh) * 2019-06-15 2022-02-08 汉义生物科技（北京）有限公司 大麻素在制备吸入给药药物中的应用
WO2022036462A1 (en) * 2020-08-21 2022-02-24 Organigram Inc. Buccal dosage forms comprising oligosaccharides
WO2023224960A1 (en) * 2022-05-17 2023-11-23 Orcosa Inc. Rapidly infusing cannabinoid compositions, processes of manufacture, and methods of use
WO2023250274A1 (en) 2022-06-22 2023-12-28 Ilera Therapeutics Llc Enhanced capture and dissolution matrix for cannabinoids and methods of making the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903593D0 (en) * 1989-02-16 1989-04-05 Pafra Ltd Storage of materials
GB9010742D0 (en) * 1990-05-14 1990-07-04 Quadrant Bioresources Ltd Stabilization of biological macromolecular substances
US5955448A (en) * 1994-08-19 1999-09-21 Quadrant Holdings Cambridge Limited Method for stabilization of biological substances during drying and subsequent storage and compositions thereof
IL117773A (en) * 1996-04-02 2000-10-31 Pharmos Ltd Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
GB9726916D0 (en) * 1997-12-19 1998-02-18 Danbiosyst Uk Nasal formulation
US6509005B1 (en) * 1998-10-27 2003-01-21 Virginia Commonwealth University Δ9 Tetrahydrocannabinol (Δ9 THC) solution metered dose inhaler
NL1012300C2 (nl) * 1999-06-11 2000-12-12 Rijksuniversiteit Stabilisator voor farmaca.

Also Published As

Publication number Publication date
CA2480270A1 (en) 2003-10-09
HRP20040816A2 (en) 2005-06-30
JP2005521710A (ja) 2005-07-21
ES2316759T3 (es) 2009-04-16
DE60324668D1 (de) 2008-12-24
MXPA04009673A (es) 2005-01-11
NO20044749L (no) 2005-01-03
EP1492503A1 (en) 2005-01-05
HK1078458A1 (en) 2006-03-17
CN100592903C (zh) 2010-03-03
JP4491241B2 (ja) 2010-06-30
DK1492503T3 (da) 2009-03-09
PL209134B1 (pl) 2011-07-29
WO2003082246A1 (en) 2003-10-09
RU2004132190A (ru) 2005-04-20
CN1642527A (zh) 2005-07-20
ATE413862T1 (de) 2008-11-15
AU2003240759B2 (en) 2008-02-14
EP1492503B1 (en) 2008-11-12
AU2003240759A1 (en) 2003-10-13
PL372921A1 (en) 2005-08-08
RU2311178C2 (ru) 2007-11-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2260 DE 29/04/2014.