BR0308475A - Formulação de eplerenona estável na armazenagem - Google Patents
Formulação de eplerenona estável na armazenagemInfo
- Publication number
- BR0308475A BR0308475A BR0308475-2A BR0308475A BR0308475A BR 0308475 A BR0308475 A BR 0308475A BR 0308475 A BR0308475 A BR 0308475A BR 0308475 A BR0308475 A BR 0308475A
- Authority
- BR
- Brazil
- Prior art keywords
- storage stable
- formulation
- eplerenone
- eplerenone formulation
- stable eplerenone
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
"FORMULAçãO DE EPLERENONA ESTáVEL NA ARMAZENAGEM". é proporcionada uma composição farmacêutica distribuível parenteralmente compreendendo eplerenona e um líquido solvente possuindo a eplerenona em solução no mesmo. As composições da invenção são estáveis sob armazenagem.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36606402P | 2002-03-20 | 2002-03-20 | |
PCT/US2003/008432 WO2003080181A2 (en) | 2002-03-20 | 2003-03-20 | Storage stable eplerenone formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0308475A true BR0308475A (pt) | 2005-01-11 |
Family
ID=28454746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0308475-2A BR0308475A (pt) | 2002-03-20 | 2003-03-20 | Formulação de eplerenona estável na armazenagem |
Country Status (8)
Country | Link |
---|---|
US (2) | US20040072797A1 (pt) |
EP (1) | EP1487540A2 (pt) |
JP (1) | JP2005520856A (pt) |
AU (1) | AU2003225871A1 (pt) |
BR (1) | BR0308475A (pt) |
CA (1) | CA2479383A1 (pt) |
MX (1) | MXPA04009037A (pt) |
WO (1) | WO2003080181A2 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101578103B (zh) * | 2006-06-29 | 2013-09-25 | 林科杰诺米克斯株式会社 | 抗生素的注射剂及其给予液 |
WO2013179310A1 (en) * | 2012-05-31 | 2013-12-05 | Mylan Laboratories Limited | Stable aqueous compositions of pemetrexed |
CN112089843B (zh) * | 2020-10-13 | 2022-11-04 | 合肥工业大学 | 一种抗心力衰竭的联用组合药物及其在制备抗心力衰竭药物中的应用 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3459731A (en) * | 1966-12-16 | 1969-08-05 | Corn Products Co | Cyclodextrin polyethers and their production |
US3535152A (en) * | 1966-12-27 | 1970-10-20 | Johnson & Johnson | Heat cured pressure-sensitive adhesive tape |
HU191101B (en) * | 1983-02-14 | 1987-01-28 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu | Process for preparing water-soluble cyclodextrin polymers substituted with ionic groups |
FI77669C (fi) * | 1983-04-13 | 1989-04-10 | Ciba Geigy Ag | 20-spiroxaner och analoger, som innehaoller en oeppen ring e, foerfarande foer deras framstaellning samt dessa innehaollande farmaceutiska preparat. |
US4971813A (en) * | 1990-02-13 | 1990-11-20 | The Procter & Gamble Company | Process for making concentrated low calorie fruit juice |
JP2879395B2 (ja) * | 1992-10-26 | 1999-04-05 | 富士写真フイルム株式会社 | ロダシアニン化合物及びシクロデキストリンを含有する抗癌性組成物 |
BE1008307A3 (fr) * | 1994-06-16 | 1996-04-02 | Europharmaceuticals Sa | Sel de nimesulide hydrosoluble, solution aqueuse le contenant, sa preparation et son utilisation. |
US5807895A (en) * | 1994-11-29 | 1998-09-15 | Schwarz Pharma, Inc. | Use of prostaglandin E1, E2 or analogs to prevent renal failure induced by medical tests that utilize contrast media agents |
US5824668A (en) * | 1996-11-07 | 1998-10-20 | Supergen, Inc. | Formulation for administration of steroid compounds |
UA74141C2 (uk) * | 1998-12-09 | 2005-11-15 | Дж.Д. Сірл Енд Ко. | Фармацевтична композиція на основі тонкоподрібненого еплеренону (варіанти), спосіб її одержання та спосіб лікування розладів, опосередкованих альдостероном (варіанти) |
JP2003516414A (ja) * | 1999-12-08 | 2003-05-13 | ファルマシア コーポレイション | より高い溶解速度を示すエプレレノン結晶形 |
-
2003
- 2003-03-20 MX MXPA04009037A patent/MXPA04009037A/es unknown
- 2003-03-20 AU AU2003225871A patent/AU2003225871A1/en not_active Abandoned
- 2003-03-20 US US10/393,493 patent/US20040072797A1/en not_active Abandoned
- 2003-03-20 WO PCT/US2003/008432 patent/WO2003080181A2/en not_active Application Discontinuation
- 2003-03-20 EP EP03745141A patent/EP1487540A2/en not_active Withdrawn
- 2003-03-20 JP JP2003578004A patent/JP2005520856A/ja not_active Withdrawn
- 2003-03-20 BR BR0308475-2A patent/BR0308475A/pt not_active IP Right Cessation
- 2003-03-20 CA CA002479383A patent/CA2479383A1/en not_active Abandoned
-
2004
- 2004-12-01 US US11/001,389 patent/US20050080046A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU2003225871A1 (en) | 2003-10-08 |
US20040072797A1 (en) | 2004-04-15 |
JP2005520856A (ja) | 2005-07-14 |
WO2003080181A2 (en) | 2003-10-02 |
WO2003080181A3 (en) | 2004-02-05 |
EP1487540A2 (en) | 2004-12-22 |
CA2479383A1 (en) | 2003-10-02 |
US20050080046A1 (en) | 2005-04-14 |
MXPA04009037A (es) | 2005-01-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2625344T3 (es) | Composiciones hemostáticas que contienen una solución estéril de trombina | |
ATE327977T1 (de) | Tetrahydrochinolin-derivate als crth2 antagonisten | |
RS51764B (en) | TRANSDERMAL PHARMACEUTICAL COMPOSITION | |
BR0014486A (pt) | Composições farmacêuticas contendo polipeptìdeo lìquido estabilizado | |
PT1263725E (pt) | Novos compostos | |
DE69932133D1 (de) | Zweiphasen kosmetische zusammensetzung | |
BRPI0409591A (pt) | composições com múltiplas fases lìquidas visualmente distintas | |
IT1288290B1 (it) | Acido ialuronico autoreticolato e relative composizioni farmaceutiche per il trattamento delle artropatie | |
BR0111639A (pt) | Uso de uma molécula de ácido oligodeoxinucléico, e composição farmacêutica contendo a mesma | |
NO20031921D0 (no) | Flytende benzoatestersammensetninger og vandige polymersammensetninger sominneholder de samme som mykgjörere | |
AU2003261167A1 (en) | Liquid dosage compositions of stable nanoparticulate active agents | |
BRPI0417721B8 (pt) | kit contendo um medicamento farmacêutico, método para preparar uma formulação líquida de um fator recombinante viia, composição e métodos para preparar as composições | |
BR0316310A (pt) | Composições farmacêuticas tendo um veìculo modificado | |
IL178128A0 (en) | Salts of 3-0-(3',3'-dimethyl-succinyl) betulinic acid and pharmaceutical compositions containing the same | |
BR9714310A (pt) | Composição farmacêutica | |
BR0100046A (pt) | Copolìmeros reticulados solúveis em água ou intumescìveis em água | |
BRPI0406801B8 (pt) | derivados de tieno-pirimidinodiona e uso dos mesmos na modulação de doenças autoimunes | |
BR0107869A (pt) | Composições farmacêuticas eletrogiradas | |
BR9914932A (pt) | Processo para a manufatura de uma composição de isotretinoìna, composição de isotretinoìna micronizada, forma de dosagem unitária para administração enteral e composição farmacêutica na forma de dosagem unitária | |
EP2263651A3 (en) | Low viscosity liquid dosage forms | |
PT1073470E (pt) | Composicoes farmaceuticas contendo compostos com actividade capaz de melhorar a absorcao de ingredientes activos | |
BR0111678A (pt) | Composições medicinais contendo derivados de propenona | |
BR0007294A (pt) | Formulações farmacêuticas aperfeiçoadas | |
DK0722313T3 (da) | Viskoelastiske sammensætninger af fluorerede organiske forbindelser | |
ECSP055566A (es) | Formulaciones de depósito de corta duración |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 4A, 5A, 6A E 7A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/585 (2006.01), A61P 9/04 (2006.01), A61P 9 |