BR0307611A - Métodos de tratar um distúrbio oftalmológico, e de prevenir ou tratar um distúrbio de um nervo, e, uso de um composto - Google Patents

Métodos de tratar um distúrbio oftalmológico, e de prevenir ou tratar um distúrbio de um nervo, e, uso de um composto

Info

Publication number
BR0307611A
BR0307611A BR0307611-3A BR0307611A BR0307611A BR 0307611 A BR0307611 A BR 0307611A BR 0307611 A BR0307611 A BR 0307611A BR 0307611 A BR0307611 A BR 0307611A
Authority
BR
Brazil
Prior art keywords
treating
compound
disorder
methods
nerve
Prior art date
Application number
BR0307611-3A
Other languages
English (en)
Inventor
Vicken Karageozian
David Castillejos
John Park
Original Assignee
Vitreo Retinal Technologies In
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitreo Retinal Technologies In filed Critical Vitreo Retinal Technologies In
Publication of BR0307611A publication Critical patent/BR0307611A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

"MéTODOS DE TRATAR UM DISTúRBIO OFTALMOLóGICO, E DE PREVENIR OU TRATAR UM DISTúRBIO DE UM NERVO, E, USO DE UM COMPOSTO". Métodos de tratar distúrbios do olho e/ou distúrbios de um nervo em um paciente humano ou veterinário por meio de fornecimento ao paciente de uma quantidade terapeuticamente eficaz de um composto selecionado do grupo de; uréia, derivados de uréia, tiouréia, derivados de tiouréia, guanidina, derivados de guanidina e compostos apresentando Fórmula geral I como apresentado aqui. Para aplicações oftálmicas, o composto pode ser fornecido via injeção intravitreal de tal forma que o composto cause liquefação do vítreo, descolamento vitreorretinal posterior e outros efeitos.
BR0307611-3A 2002-02-13 2003-02-13 Métodos de tratar um distúrbio oftalmológico, e de prevenir ou tratar um distúrbio de um nervo, e, uso de um composto BR0307611A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35734702P 2002-02-13 2002-02-13
US35757402P 2002-02-15 2002-02-15
PCT/US2003/004617 WO2003068166A2 (en) 2002-02-13 2003-02-13 Treatment of ophthalmic disorders using urea and urea derivatives

Publications (1)

Publication Number Publication Date
BR0307611A true BR0307611A (pt) 2004-12-21

Family

ID=27737587

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307611-3A BR0307611A (pt) 2002-02-13 2003-02-13 Métodos de tratar um distúrbio oftalmológico, e de prevenir ou tratar um distúrbio de um nervo, e, uso de um composto

Country Status (15)

Country Link
EP (1) EP1480678B1 (pt)
JP (1) JP2005521681A (pt)
KR (1) KR20040094687A (pt)
CN (1) CN1633308A (pt)
AT (1) ATE428412T1 (pt)
AU (1) AU2003213084B2 (pt)
BR (1) BR0307611A (pt)
CA (1) CA2475338C (pt)
DE (1) DE60327179D1 (pt)
ES (1) ES2325360T3 (pt)
IL (1) IL163374A (pt)
MX (1) MXPA04007802A (pt)
NZ (1) NZ535165A (pt)
RU (1) RU2339369C2 (pt)
WO (1) WO2003068166A2 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7977385B2 (en) 2000-03-02 2011-07-12 Numoda Biotechnologies, Inc. Agents for corneal or intrastromal administration to treat or prevent disorders of the eye
US20030199574A1 (en) 2000-03-02 2003-10-23 Vitreo-Retinal Technologies, Inc. Treatment of ophthalmic disorders using urea and urea derivatives
AU2003213858A1 (en) * 2002-03-14 2003-09-29 Vitreo-Retinal Technologies, Inc. Agents for corneal or intrastromal administration to treat or prevent disorders of the eye
JP7079250B2 (ja) * 2016-08-18 2022-06-01 ブレマー，トロイ リポソーム構築物を用いた黄斑細胞及び網膜細胞への尿素の送達
CA3103436A1 (en) * 2018-06-11 2019-12-19 The Regents Of The University Of California Demethylation to treat eye disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8908063D0 (en) * 1989-04-11 1989-05-24 Beecham Group Plc Novel compounds
EP0705100B1 (en) * 1993-05-27 2003-07-30 CeNes Limited Therapeutic substituted guanidines
US5470881A (en) * 1993-09-09 1995-11-28 West Virginia University Research Corporation Urea ophthalmic ointment and solution
EP0739200A4 (en) * 1993-11-23 1997-12-17 Cambridge Neuroscience Inc SUBSTITUTED GUANIDINES FOR THERAPEUTIC USE
US5441984A (en) * 1994-01-06 1995-08-15 Eli Lilly And Company Urea, thiourea and guanidine derivatives
US6395758B1 (en) * 1998-08-14 2002-05-28 Gpi Nil Holdings, Inc. Small molecule carbamates or ureas for vision and memory disorders
WO2000051620A1 (en) * 1999-03-02 2000-09-08 Vitreo-Retinal Technologies, Inc. Agents for intravitreal administration to treat or prevent disorders of the eye
AU763750B2 (en) * 1999-04-05 2003-07-31 City Of Hope Novel inhibitors of formation of advanced glycation endproducts (AGE's)
US6313172B1 (en) * 2000-04-13 2001-11-06 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity
US6545182B2 (en) * 2000-04-13 2003-04-08 Allergan Sales, Inc. Methods and compositions for modulating alpha adrenergic receptor activity

Also Published As

Publication number Publication date
IL163374A (en) 2012-01-31
WO2003068166A2 (en) 2003-08-21
ATE428412T1 (de) 2009-05-15
WO2003068166A3 (en) 2003-12-24
CA2475338A1 (en) 2003-08-21
ES2325360T3 (es) 2009-09-02
RU2339369C2 (ru) 2008-11-27
AU2003213084A1 (en) 2003-09-04
EP1480678B1 (en) 2009-04-15
CN1633308A (zh) 2005-06-29
DE60327179D1 (de) 2009-05-28
JP2005521681A (ja) 2005-07-21
KR20040094687A (ko) 2004-11-10
AU2003213084B2 (en) 2008-06-26
RU2004127610A (ru) 2005-06-27
MXPA04007802A (es) 2005-04-19
NZ535165A (en) 2006-08-31
EP1480678A2 (en) 2004-12-01
CA2475338C (en) 2014-08-19
EP1480678A4 (en) 2005-08-24

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CL. A61K 47/34; A61P 27/02

Ipc: A61K 47/34 (2011.01), A61P 27/02 (2011.01)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8, 10, 11, 13, 22 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.