BR0215187A - Composições farmacêuticas que compreendem uma ciclosporina, um tensoativo hidrofìlico e um tensoativo lipofìlico - Google Patents
Composições farmacêuticas que compreendem uma ciclosporina, um tensoativo hidrofìlico e um tensoativo lipofìlicoInfo
- Publication number
- BR0215187A BR0215187A BR0215187-1A BR0215187A BR0215187A BR 0215187 A BR0215187 A BR 0215187A BR 0215187 A BR0215187 A BR 0215187A BR 0215187 A BR0215187 A BR 0215187A
- Authority
- BR
- Brazil
- Prior art keywords
- surfactant
- pharmaceutical compositions
- cyclosporine
- lipophilic
- hydrophilic
- Prior art date
Links
- 239000004094 surface-active agent Substances 0.000 title abstract 7
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 4
- 108010036949 Cyclosporine Proteins 0.000 title abstract 3
- 229960001265 ciclosporin Drugs 0.000 title abstract 3
- 229930182912 cyclosporin Natural products 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000002904 solvent Substances 0.000 abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ51626901A NZ516269A (en) | 2001-12-20 | 2001-12-20 | Pharmaceutical compositions comprising cyclosporine |
| NZ51983702A NZ519837A (en) | 2002-06-28 | 2002-06-28 | Pharmaceutical compositions comprising a cyclosporin or cyclosporin derivative |
| PCT/CA2002/001968 WO2003053404A1 (en) | 2001-12-20 | 2002-12-19 | Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0215187A true BR0215187A (pt) | 2004-11-16 |
Family
ID=26652297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0215187-1A BR0215187A (pt) | 2001-12-20 | 2002-12-19 | Composições farmacêuticas que compreendem uma ciclosporina, um tensoativo hidrofìlico e um tensoativo lipofìlico |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20050129718A1 (enExample) |
| EP (1) | EP1455753A1 (enExample) |
| JP (1) | JP2005513096A (enExample) |
| BR (1) | BR0215187A (enExample) |
| CA (1) | CA2471241A1 (enExample) |
| WO (1) | WO2003053404A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8492369B2 (en) | 2010-04-12 | 2013-07-23 | Clarus Therapeutics Inc | Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same |
| RU2623206C2 (ru) | 2005-04-15 | 2017-06-22 | Кларус Терапьютикс, Инк. | Фармацевтические системы доставки для гидрофобных лекарственных средств и композиций, их содержащих |
| US7276476B2 (en) * | 2005-07-13 | 2007-10-02 | Allergan, Inc. | Cyclosporin compositions |
| US7297679B2 (en) | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
| US20070015691A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
| US7202209B2 (en) * | 2005-07-13 | 2007-04-10 | Allergan, Inc. | Cyclosporin compositions |
| US7288520B2 (en) | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| US20070015693A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
| US7501393B2 (en) * | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
| US7745400B2 (en) * | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
| US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
| AU2007221196B2 (en) * | 2006-02-22 | 2011-08-04 | Novartis Pharma Ag | System for delivering nebulized cyclosporine and methods of treatment |
| WO2008122965A2 (en) | 2007-04-04 | 2008-10-16 | Sigmoid Pharma Limited | Pharmaceutical cyclosporin compositions |
| WO2010133609A2 (en) | 2009-05-18 | 2010-11-25 | Sigmoid Pharma Limited | Composition comprising oil drops |
| US9878036B2 (en) | 2009-08-12 | 2018-01-30 | Sigmoid Pharma Limited | Immunomodulatory compositions comprising a polymer matrix and an oil phase |
| JP5283654B2 (ja) * | 2010-03-30 | 2013-09-04 | 中日本カプセル 株式会社 | ソフトカプセル用の充填組成物 |
| GB201020032D0 (en) | 2010-11-25 | 2011-01-12 | Sigmoid Pharma Ltd | Composition |
| CA2835912A1 (en) * | 2011-05-20 | 2012-11-29 | Aventis Pharmaceuticals Inc. | Pharmaceutical composition comprising fexofenadine |
| GB201304662D0 (en) | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
| US10245273B2 (en) | 2013-12-26 | 2019-04-02 | Clarus Therapeutics, Inc. | Oral pharmaceutical products and methods of use combining testosterone esters with hypolipidemic agents |
| AU2015341695B2 (en) | 2014-11-07 | 2021-07-08 | Sublimity Therapeutics Limited | Compositions comprising cyclosporin |
| CA3123002A1 (en) * | 2018-12-10 | 2020-06-18 | Halo Science LLC | Stable formulations of anesthetics and associated dosage forms |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE445174B (sv) * | 1978-03-07 | 1986-06-09 | Sandoz Ag | Farmaceutisk komposition innehallande en cyklosporin och en berarsubstans |
| KR0148748B1 (ko) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | 사이클로스포린을 함유하는 약학조성물 |
| NZ247516A (en) * | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
| US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
| US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
| US5798333A (en) * | 1996-09-17 | 1998-08-25 | Sherman; Bernard C. | Water-soluble concentrates containing cyclosporins |
| NZ337316A (en) * | 1997-03-12 | 2001-06-29 | Abbott Lab | Hydrophilic binary systems comprising cyclosporine, hydrophilic phase and a surfactant for the administration of cyclosporine |
| NZ314702A (en) * | 1997-04-29 | 1998-07-28 | Bernard Charles Sherman | Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent |
| CA2285983A1 (en) * | 1997-04-29 | 1998-11-05 | Bernard Charles Sherman | Emulsion preconcentrate comprising a cyclosporin and acetylated monoglyceride |
| IN188719B (enExample) * | 1997-09-08 | 2002-11-02 | Panacea Biotec Ltd | |
| US6008191A (en) * | 1997-09-08 | 1999-12-28 | Panacea Biotec Limited | Pharmaceutical compositions containing cyclosporin |
| US6187747B1 (en) * | 1997-09-08 | 2001-02-13 | Panacea Biotech Limited | Pharmaceutical composition comprising cyclosporin |
| CN1236813C (zh) * | 1998-12-11 | 2006-01-18 | 药品处理公司 | 水难溶性药物的自乳化组合物 |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
| GB9912476D0 (en) * | 1999-05-28 | 1999-07-28 | Novartis Ag | Organic compounds |
| GB2362573A (en) * | 2000-05-25 | 2001-11-28 | Cipla Ltd | Cyclosporin formulation |
-
2002
- 2002-12-19 BR BR0215187-1A patent/BR0215187A/pt not_active Application Discontinuation
- 2002-12-19 WO PCT/CA2002/001968 patent/WO2003053404A1/en not_active Ceased
- 2002-12-19 EP EP02787270A patent/EP1455753A1/en not_active Withdrawn
- 2002-12-19 US US10/499,709 patent/US20050129718A1/en not_active Abandoned
- 2002-12-19 JP JP2003554163A patent/JP2005513096A/ja active Pending
- 2002-12-19 CA CA002471241A patent/CA2471241A1/en not_active Abandoned
-
2010
- 2010-10-13 US US12/903,859 patent/US20110028406A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20110028406A1 (en) | 2011-02-03 |
| US20050129718A1 (en) | 2005-06-16 |
| CA2471241A1 (en) | 2003-07-03 |
| EP1455753A1 (en) | 2004-09-15 |
| AU2002351597A1 (en) | 2003-07-09 |
| WO2003053404A1 (en) | 2003-07-03 |
| JP2005513096A (ja) | 2005-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0215187A (pt) | Composições farmacêuticas que compreendem uma ciclosporina, um tensoativo hidrofìlico e um tensoativo lipofìlico | |
| BR0215184A (pt) | composições farmacêuticas de derivados de taxano oralmente ativos tendo biodisponibilidade aumentada | |
| ATE270544T1 (de) | Halbfeste arzneizubereitung enthaltend isotretinoin | |
| ATE293995T1 (de) | Pharmazeutische zusammensetzungen, die wirkstoffabsorptionsfördernde verbindungen enthalten | |
| ES2110377T1 (es) | Formulacion galenica de fenofibrato y aplicacion de la misma. | |
| BR0109931A (pt) | Composições farmacêuticas | |
| WO2005020962A8 (en) | Self-nanoemulsifying oily formulation for the administration of poorly water-soluble drugs | |
| EP1992336A3 (fr) | Forme galénique pour la délivrance colique de principes actifs | |
| BR0011772A (pt) | Conjugado de droga-oligÈmero, composição farmacêutica, método de solubilização de uma droga em uma microemulsão, e, métodos para fornecer um conjugado de droga ativa - hidrófilo e um conjugado de droga ativa - peg a um sìtio de um indivìduo | |
| BR9607066A (pt) | Método, composições e conjuntos para aumentar a biodisponibilidade oral de agentes farmacêuticos | |
| BR0005139A (pt) | Emulsão cosmética ou dermatológica comportando pelo menos um sistema fotoprotetor, composição cosmética e/ou dermatológica, utilizacao da emulsão e utilização de polìmero associativo | |
| BR0307893A (pt) | Formulação oftálmica com sistema de goma | |
| ECSP045496A (es) | "preparaciones acidas de insulina con estabilidad mejorada" | |
| WO2005072343A3 (en) | Aqueous pharmaceutical compositions 2,6-diisopropylphenol (propofol) and their use | |
| DE19581805T1 (de) | Pharmazeutische Zusammensetzungen | |
| BRPI0008228B8 (pt) | composição farmacêutica contendo n-benzoil estaurosporina e agentes solubilizantes | |
| ATE554750T1 (de) | Hydrophobe pharmazeutische wirkstoffe enthaltende zubereitungen | |
| MA27285A1 (fr) | COMBINAISON D'AZELASTINE ET DE STEROiDES | |
| BRPI0208210B8 (pt) | preparação de insulina pobre em zinco e isenta de zinco com estabilidade aperfeiçoada | |
| MA29744B1 (fr) | Formulations posologiques solides de medicaments presentant une adsorption buccale amelioree | |
| ATE359779T1 (de) | Selbstemulgierende systeme zur abgabe von taxoiden | |
| BRPI0407583A (pt) | solução oftálmica lìmpida e estável | |
| BR9914631A (pt) | Composição imunológica oral indutora de tolerância para prevenção e/ou tratamento de enfermidades e método para prevenção e/ou tratamento de enfermidades | |
| KR960000247A (ko) | 사이클로스포린a 함유 조성물 및 그의 제조방법 | |
| ATE357928T1 (de) | Pharmazeutische zusammensetzung für thrombinpeptidderivaten |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |