BR0215064A - Agonistas receptores seletivos de dopamina d3 para o tratamento de disfunção sexual - Google Patents

Agonistas receptores seletivos de dopamina d3 para o tratamento de disfunção sexual

Info

Publication number
BR0215064A
BR0215064A BR0215064-6A BR0215064A BR0215064A BR 0215064 A BR0215064 A BR 0215064A BR 0215064 A BR0215064 A BR 0215064A BR 0215064 A BR0215064 A BR 0215064A
Authority
BR
Brazil
Prior art keywords
selective
dopamine
treatment
sexual dysfunction
receptor
Prior art date
Application number
BR0215064-6A
Other languages
English (en)
Inventor
Pieter Hadewijn Van Der Graaf
Christopher Peter Wayman
Andrew Douglas Baxter
Andrew Simon Cook
Stephen Kwok-Fung Wong
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR0215064A publication Critical patent/BR0215064A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

"AGONISTAS RECEPTORES SELETIVOS DE DOPAMINA D3 PARA O TRATAMENTO DE DISFUNçãO SEXUAL". O uso de uma composição que compreende um agonista receptor de dopamina D3 seletivo, em que o dito agonista receptor de dopamina D3 é pelo menos aproximadamente 15 vezes mais funcionalmente seletivo para um receptor de dopamina D3 comparado com um receptor de dopamina D2 quando medido usando-se o mesmo ensaio funcional, na preparação de um medicamento para o tratamento e/ou para a prevenção de disfunção sexual.
BR0215064-6A 2001-12-18 2002-12-10 Agonistas receptores seletivos de dopamina d3 para o tratamento de disfunção sexual BR0215064A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0130219.9A GB0130219D0 (en) 2001-12-18 2001-12-18 Compounds for the treatment of sexual dysfunction
PCT/GB2002/005595 WO2003051370A1 (en) 2001-12-18 2002-12-10 Selective dopamine d3 receptor agonists for the treatment of sexual dysfunction

Publications (1)

Publication Number Publication Date
BR0215064A true BR0215064A (pt) 2004-10-13

Family

ID=9927832

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0215064-6A BR0215064A (pt) 2001-12-18 2002-12-10 Agonistas receptores seletivos de dopamina d3 para o tratamento de disfunção sexual

Country Status (15)

Country Link
US (1) US20060052435A1 (pt)
EP (1) EP1463508A1 (pt)
JP (2) JP4214057B2 (pt)
KR (1) KR20040068299A (pt)
CN (1) CN1617727A (pt)
AU (1) AU2002352372A1 (pt)
BR (1) BR0215064A (pt)
CA (1) CA2470624A1 (pt)
GB (1) GB0130219D0 (pt)
IL (1) IL162455A0 (pt)
MX (1) MXPA04006079A (pt)
NZ (1) NZ533513A (pt)
PL (1) PL370842A1 (pt)
WO (1) WO2003051370A1 (pt)
ZA (1) ZA200403906B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60040089D1 (de) 1999-11-19 2008-10-09 Solvay Pharm Bv Menschliches homolog aus der familie der metalloproteasen
PL376452A1 (en) * 2002-10-25 2005-12-27 Pharmacia & Upjohn Company Llc Use of heterocyclic amine-type compounds as neuroprotective agents
WO2004052372A1 (en) * 2002-12-10 2004-06-24 Pfizer Limited Morpholine derivatives for use as dopamine agonists in the treatment of i.a. sexual dysfunction
US7323462B2 (en) 2002-12-10 2008-01-29 Pfizer Inc. Morpholine dopamine agonists
WO2005116027A2 (en) * 2004-05-26 2005-12-08 Pfizer Limted Indazole and indolone derivatives and their use as pharmaceuticals
EA200601982A1 (ru) * 2004-05-27 2007-04-27 Пфайзер Инк. Производные аминопиридина в качестве селективных агонистов d3 - дофаминовых рецепторов
US9227944B2 (en) 2008-10-10 2016-01-05 Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China Dopamine D3 receptor ligands and preparation and medical uses of the same
WO2010040274A1 (zh) 2008-10-10 2010-04-15 中国人民解放军军事医学科学院毒物药物研究所 新型多巴胺d3受体配体，其制备方法及其医药用途
US20100318371A1 (en) * 2009-06-11 2010-12-16 Halliburton Energy Services, Inc. Comprehensive hazard evaluation system and method for chemicals and products
CN114113628A (zh) * 2021-11-08 2022-03-01 华东师范大学 多巴胺d2受体在嗅觉外周调控及制备治疗嗅觉异常药物中的应用

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Also Published As

Publication number Publication date
CA2470624A1 (en) 2003-06-26
IL162455A0 (en) 2005-11-20
US20060052435A1 (en) 2006-03-09
AU2002352372A1 (en) 2003-06-30
KR20040068299A (ko) 2004-07-30
WO2003051370A8 (en) 2003-10-02
ZA200403906B (en) 2005-06-22
JP4214057B2 (ja) 2009-01-28
WO2003051370A1 (en) 2003-06-26
JP2005516014A (ja) 2005-06-02
EP1463508A1 (en) 2004-10-06
MXPA04006079A (es) 2004-09-27
NZ533513A (en) 2006-04-28
GB0130219D0 (en) 2002-02-06
PL370842A1 (en) 2005-05-30
JP2008266338A (ja) 2008-11-06
CN1617727A (zh) 2005-05-18

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A(S) 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE A 8.6 DA RPI 2108 DE 31/05/2011.