BR0214018A - Métodos e composições para a correção de distúrbios de condução cardìaca - Google Patents
Métodos e composições para a correção de distúrbios de condução cardìacaInfo
- Publication number
- BR0214018A BR0214018A BR0214018-7A BR0214018A BR0214018A BR 0214018 A BR0214018 A BR 0214018A BR 0214018 A BR0214018 A BR 0214018A BR 0214018 A BR0214018 A BR 0214018A
- Authority
- BR
- Brazil
- Prior art keywords
- connexin
- cells
- methods
- correction
- compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 208000020597 Cardiac conduction disease Diseases 0.000 title 1
- 102000010970 Connexin Human genes 0.000 abstract 3
- 108050001175 Connexin Proteins 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 3
- 102000001045 Connexin 43 Human genes 0.000 abstract 2
- 108010069241 Connexin 43 Proteins 0.000 abstract 2
- 210000005003 heart tissue Anatomy 0.000 abstract 2
- 210000004413 cardiac myocyte Anatomy 0.000 abstract 1
- 238000004891 communication Methods 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000012239 gene modification Methods 0.000 abstract 1
- 230000005017 genetic modification Effects 0.000 abstract 1
- 235000013617 genetically modified food Nutrition 0.000 abstract 1
- 210000002064 heart cell Anatomy 0.000 abstract 1
- 208000019622 heart disease Diseases 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000002363 skeletal muscle cell Anatomy 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33735201P | 2001-11-08 | 2001-11-08 | |
| PCT/US2002/035932 WO2003039344A2 (en) | 2001-11-08 | 2002-11-07 | Methods and compositions for correction of cardiac conduction disturbances |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0214018A true BR0214018A (pt) | 2005-04-19 |
Family
ID=23320214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0214018-7A BR0214018A (pt) | 2001-11-08 | 2002-11-07 | Métodos e composições para a correção de distúrbios de condução cardìaca |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7252819B2 (enExample) |
| EP (1) | EP1453382A4 (enExample) |
| JP (1) | JP2005527482A (enExample) |
| CN (1) | CN1612691A (enExample) |
| AU (1) | AU2002359371A1 (enExample) |
| BR (1) | BR0214018A (enExample) |
| CA (1) | CA2465476A1 (enExample) |
| IL (1) | IL161862A0 (enExample) |
| MX (1) | MXPA04004396A (enExample) |
| WO (1) | WO2003039344A2 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002359371A1 (en) | 2001-11-08 | 2003-05-19 | The Regents Of The University Of California | Methods and compositions for correction of cardiac conduction disturbances |
| US20060002898A1 (en) * | 2002-05-08 | 2006-01-05 | Lee Randall J | Methods and compositions for correction of cardiac conduction disturbances |
| JP2005538945A (ja) * | 2002-05-08 | 2005-12-22 | ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア | 心不整脈を線維芽細胞で治療するためのシステム及び方法 |
| US20040106896A1 (en) * | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| US7627373B2 (en) | 2002-11-30 | 2009-12-01 | Cardiac Pacemakers, Inc. | Method and apparatus for cell and electrical therapy of living tissue |
| US7794702B2 (en) * | 2003-01-15 | 2010-09-14 | The Trustees Of Columbia University In The City Of New York | Mesenchymal stem cells as a vehicle for ion channel transfer in syncytial structures |
| EP1691747B1 (en) * | 2003-11-13 | 2012-05-23 | CardioPolymers, Inc. | Control of cardiac arrhythmias by modification of neuronal conduction within fat pads of the heart |
| US8073538B2 (en) * | 2003-11-13 | 2011-12-06 | Cardio Polymers, Inc. | Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart |
| US20060128647A1 (en) * | 2003-12-24 | 2006-06-15 | Daniel Sigg | Novel oligonucleotides and treating cardiac disorders by using the same |
| US7840263B2 (en) * | 2004-02-27 | 2010-11-23 | Cardiac Pacemakers, Inc. | Method and apparatus for device controlled gene expression |
| US20080260705A1 (en) * | 2004-03-22 | 2008-10-23 | The Johns Hopkins University | Preventing Arrhythmias Associated with Cell Transplantation |
| US7764995B2 (en) | 2004-06-07 | 2010-07-27 | Cardiac Pacemakers, Inc. | Method and apparatus to modulate cellular regeneration post myocardial infarct |
| US20050277124A1 (en) * | 2004-06-10 | 2005-12-15 | White Steven M | Cardiac conduction system cells and uses thereof |
| US20050283218A1 (en) * | 2004-06-22 | 2005-12-22 | Williams Michael S | Implantable chamber for biological induction or enhancement of muscle contraction |
| WO2006044589A2 (en) * | 2004-10-13 | 2006-04-27 | Medtronic, Inc. | Cellular and genetic intervention to treat ventricular tachycardia |
| US8060219B2 (en) | 2004-12-20 | 2011-11-15 | Cardiac Pacemakers, Inc. | Epicardial patch including isolated extracellular matrix with pacing electrodes |
| US7981065B2 (en) | 2004-12-20 | 2011-07-19 | Cardiac Pacemakers, Inc. | Lead electrode incorporating extracellular matrix |
| WO2007147014A2 (en) * | 2006-06-13 | 2007-12-21 | Fmc Biopolymer As | Method and systems for using biopolymer-based beads and hydrogels |
| US9375313B2 (en) * | 2006-09-08 | 2016-06-28 | The Regents Of The University Of California | Intramyocardial patterning for global cardiac resizing and reshaping |
| US7787949B2 (en) * | 2006-10-30 | 2010-08-31 | Medtronic, Inc. | Biological pacemaker compositions and systems incorporating interstitial cells of Cajal |
| JP2010523264A (ja) * | 2007-04-11 | 2010-07-15 | ヘンリー フォード ヘルス システム | 心臓の静脈系を用いた心臓の修復、リサイジング、およびリシェイピング |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| WO2008137115A1 (en) | 2007-05-03 | 2008-11-13 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| WO2008154033A2 (en) * | 2007-06-11 | 2008-12-18 | Symphony Medical, Inc. | Cardiac patterning for improving diastolic function |
| EP2203129A4 (en) * | 2007-10-15 | 2011-11-23 | Univ Wake Forest Health Sciences | METHOD AND COMPOSITIONS FOR PRINTING BIOCOMPATIBLE NANOROUS COMPOSITES FROM AUTOLOGOUS TISSUE |
| WO2009111755A2 (en) * | 2008-03-07 | 2009-09-11 | The Trustees Of Columbia University In The City Of New York | Compensating for atrioventricular block using a nucleic acid encoding a sodium channel or gap junction protein |
| CN106178118A (zh) | 2008-09-30 | 2016-12-07 | 加利福尼亚大学董事会 | 用于组织修复的使用细胞外基质的组合物和方法 |
| AU2010300611B2 (en) | 2009-10-02 | 2015-12-10 | Baxalta GmbH | Hematopoietic stem cells for use in the treatment of a kidney injury |
| CN106619723A (zh) | 2010-08-24 | 2017-05-10 | 加利福尼亚大学董事会 | 用于心脏治疗的组合物和方法 |
| US9677042B2 (en) | 2010-10-08 | 2017-06-13 | Terumo Bct, Inc. | Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| WO2013036708A2 (en) | 2011-09-07 | 2013-03-14 | The Regents Of The University Of California | Compositions and methods for tissue repair with extracellular matrices |
| JP2015508101A (ja) | 2012-02-21 | 2015-03-16 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | Cd34+細胞を含む薬学的組成物 |
| EP3068867B1 (en) | 2013-11-16 | 2018-04-18 | Terumo BCT, Inc. | Expanding cells in a bioreactor |
| WO2015120216A1 (en) | 2014-02-07 | 2015-08-13 | Gojo Industries, Inc. | Compositions and methods with efficacy against spores and other organisms |
| CN106232800B (zh) | 2014-03-25 | 2020-07-03 | 泰尔茂比司特公司 | 介质的被动替代 |
| EP3198006B1 (en) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Scheduled feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CN109415696A (zh) | 2016-05-25 | 2019-03-01 | 泰尔茂比司特公司 | 细胞扩增 |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| WO2018184028A2 (en) | 2017-03-31 | 2018-10-04 | Terumo Bct, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| WO2019060619A1 (en) * | 2017-09-20 | 2019-03-28 | The Regents Of The University Of California | STRATEGY OF GENE THERAPY FOR RESTORING ELECTRICAL AND CARDIAC FUNCTION AND CARDIAC STRUCTURE IN ARYTHMOGENIC RIGHT VENTRICULAR CARDIOMYOPATHY |
| US12098385B2 (en) | 2017-09-20 | 2024-09-24 | The Regents Of The University Of California | Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy |
| JP7705950B2 (ja) | 2021-03-23 | 2025-07-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞を増殖する方法 |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
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| US5130141A (en) | 1988-05-24 | 1992-07-14 | Law Peter K | Compositions for and methods of treating muscle degeneration and weakness |
| US5030204A (en) | 1988-09-28 | 1991-07-09 | Advanced Cardiovascular Systems, Inc. | Guiding catheter with controllable distal tip |
| US5103821A (en) | 1989-03-06 | 1992-04-14 | Angeion Corporation | Method of providing a biological pacemaker |
| WO1990010471A1 (en) | 1989-03-06 | 1990-09-20 | Angeion Corporation | Method of providing a biological pacemaker |
| US5693622A (en) | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5087243A (en) | 1990-06-18 | 1992-02-11 | Boaz Avitall | Myocardial iontophoresis |
| US5661133B1 (en) | 1991-11-12 | 1999-06-01 | Univ Michigan | Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein |
| US5709854A (en) | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US5551426A (en) | 1993-07-14 | 1996-09-03 | Hummel; John D. | Intracardiac ablation and mapping catheter |
| US5602301A (en) | 1993-11-16 | 1997-02-11 | Indiana University Foundation | Non-human mammal having a graft and methods of delivering protein to myocardial tissue |
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| US6059726A (en) | 1996-11-08 | 2000-05-09 | The Regents Of The University Of California | Method for locating the atrio-ventricular (AV) junction of the heart and injecting active substances therein |
| US6239117B1 (en) | 1997-02-13 | 2001-05-29 | Albert Einstein College Of Medicine Of Yeshiva University | Gene therapy for regulating bladder smooth muscle tone |
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| AU2002359371A1 (en) | 2001-11-08 | 2003-05-19 | The Regents Of The University Of California | Methods and compositions for correction of cardiac conduction disturbances |
| US6932804B2 (en) | 2003-01-21 | 2005-08-23 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| JP2005538945A (ja) | 2002-05-08 | 2005-12-22 | ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア | 心不整脈を線維芽細胞で治療するためのシステム及び方法 |
| US20040106896A1 (en) | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| US20060002898A1 (en) | 2002-05-08 | 2006-01-05 | Lee Randall J | Methods and compositions for correction of cardiac conduction disturbances |
| AU2003239418B2 (en) | 2002-05-08 | 2008-01-31 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| US7317950B2 (en) | 2002-11-16 | 2008-01-08 | The Regents Of The University Of California | Cardiac stimulation system with delivery of conductive agent |
-
2002
- 2002-11-07 AU AU2002359371A patent/AU2002359371A1/en not_active Abandoned
- 2002-11-07 WO PCT/US2002/035932 patent/WO2003039344A2/en not_active Ceased
- 2002-11-07 US US10/291,202 patent/US7252819B2/en not_active Expired - Fee Related
- 2002-11-07 JP JP2003541442A patent/JP2005527482A/ja not_active Withdrawn
- 2002-11-07 IL IL16186202A patent/IL161862A0/xx unknown
- 2002-11-07 EP EP02793904A patent/EP1453382A4/en not_active Withdrawn
- 2002-11-07 CA CA002465476A patent/CA2465476A1/en not_active Abandoned
- 2002-11-07 CN CNA028269055A patent/CN1612691A/zh active Pending
- 2002-11-07 BR BR0214018-7A patent/BR0214018A/pt not_active IP Right Cessation
-
2004
- 2004-05-07 MX MXPA04004396A patent/MXPA04004396A/es unknown
-
2006
- 2006-12-05 US US11/635,810 patent/US7494644B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002359371A1 (en) | 2003-05-19 |
| US20080019953A1 (en) | 2008-01-24 |
| JP2005527482A (ja) | 2005-09-15 |
| US7252819B2 (en) | 2007-08-07 |
| CN1612691A (zh) | 2005-05-04 |
| IL161862A0 (en) | 2005-11-20 |
| WO2003039344A2 (en) | 2003-05-15 |
| US7494644B2 (en) | 2009-02-24 |
| MXPA04004396A (es) | 2004-08-11 |
| WO2003039344A3 (en) | 2003-12-31 |
| US20030104568A1 (en) | 2003-06-05 |
| EP1453382A2 (en) | 2004-09-08 |
| CA2465476A1 (en) | 2003-05-15 |
| EP1453382A4 (en) | 2005-05-18 |
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