MXPA04004396A - Metodos y composiciones para correccion de perturbaciones de conduccion cardiaca. - Google Patents
Metodos y composiciones para correccion de perturbaciones de conduccion cardiaca.Info
- Publication number
- MXPA04004396A MXPA04004396A MXPA04004396A MXPA04004396A MXPA04004396A MX PA04004396 A MXPA04004396 A MX PA04004396A MX PA04004396 A MXPA04004396 A MX PA04004396A MX PA04004396 A MXPA04004396 A MX PA04004396A MX PA04004396 A MXPA04004396 A MX PA04004396A
- Authority
- MX
- Mexico
- Prior art keywords
- connexin
- cells
- cardiac
- recombinant
- correction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33735201P | 2001-11-08 | 2001-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA04004396A true MXPA04004396A (es) | 2004-08-11 |
Family
ID=23320214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA04004396A MXPA04004396A (es) | 2001-11-08 | 2004-05-07 | Metodos y composiciones para correccion de perturbaciones de conduccion cardiaca. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7252819B2 (enExample) |
| EP (1) | EP1453382A4 (enExample) |
| JP (1) | JP2005527482A (enExample) |
| CN (1) | CN1612691A (enExample) |
| AU (1) | AU2002359371A1 (enExample) |
| BR (1) | BR0214018A (enExample) |
| CA (1) | CA2465476A1 (enExample) |
| IL (1) | IL161862A0 (enExample) |
| MX (1) | MXPA04004396A (enExample) |
| WO (1) | WO2003039344A2 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL161862A0 (en) * | 2001-11-08 | 2005-11-20 | Univ California | Methods and compositions for correction of cardiac conduction disturbances |
| EP1503716A4 (en) * | 2002-05-08 | 2007-07-04 | Univ California | SYSTEM AND METHOD FOR THE TREATMENT OF CARDIAC ARCHITECTURES WITH FIBROBLASTED CELLS |
| US20040106896A1 (en) * | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| WO2003094697A2 (en) * | 2002-05-08 | 2003-11-20 | The Regents Of The University Of California | Methods and compositions for correction of cardiac conduction disturbances |
| US7627373B2 (en) | 2002-11-30 | 2009-12-01 | Cardiac Pacemakers, Inc. | Method and apparatus for cell and electrical therapy of living tissue |
| US7794702B2 (en) * | 2003-01-15 | 2010-09-14 | The Trustees Of Columbia University In The City Of New York | Mesenchymal stem cells as a vehicle for ion channel transfer in syncytial structures |
| JP2007511291A (ja) * | 2003-11-13 | 2007-05-10 | シンフォニー メディカル, インコーポレイテッド | 心臓の脂肪パッド内の神経伝達の改変による不整脈の制御 |
| US8073538B2 (en) * | 2003-11-13 | 2011-12-06 | Cardio Polymers, Inc. | Treatment of cardiac arrhythmia by modification of neuronal signaling through fat pads of the heart |
| US20060128647A1 (en) * | 2003-12-24 | 2006-06-15 | Daniel Sigg | Novel oligonucleotides and treating cardiac disorders by using the same |
| US7840263B2 (en) * | 2004-02-27 | 2010-11-23 | Cardiac Pacemakers, Inc. | Method and apparatus for device controlled gene expression |
| EP1768702A4 (en) * | 2004-03-22 | 2008-08-13 | Univ Johns Hopkins | PREVENTION OF ARRHYTHMIA RELATED TO CELLULAR TRANSPLANTATION |
| US7764995B2 (en) | 2004-06-07 | 2010-07-27 | Cardiac Pacemakers, Inc. | Method and apparatus to modulate cellular regeneration post myocardial infarct |
| US20050277124A1 (en) | 2004-06-10 | 2005-12-15 | White Steven M | Cardiac conduction system cells and uses thereof |
| US20050283218A1 (en) * | 2004-06-22 | 2005-12-22 | Williams Michael S | Implantable chamber for biological induction or enhancement of muscle contraction |
| US20060088503A1 (en) * | 2004-10-13 | 2006-04-27 | Vinod Sharma | Cellular and genetic intervention to treat ventricular tachycardia |
| US8060219B2 (en) | 2004-12-20 | 2011-11-15 | Cardiac Pacemakers, Inc. | Epicardial patch including isolated extracellular matrix with pacing electrodes |
| US7981065B2 (en) | 2004-12-20 | 2011-07-19 | Cardiac Pacemakers, Inc. | Lead electrode incorporating extracellular matrix |
| US20080138416A1 (en) * | 2006-06-13 | 2008-06-12 | Fmc Biopolymer As | Method and systems for using biopolymer-based beads and hydrogels |
| AU2007292923B2 (en) | 2006-09-08 | 2013-10-03 | Cardiopolymers, Inc. | Intramyocardial patterning for global cardiac resizing and reshaping |
| US7787949B2 (en) * | 2006-10-30 | 2010-08-31 | Medtronic, Inc. | Biological pacemaker compositions and systems incorporating interstitial cells of Cajal |
| WO2008127607A2 (en) * | 2007-04-11 | 2008-10-23 | Henry Ford Health System | Cardiac repair, resizing and reshaping using the venous system of the heart |
| WO2008137115A1 (en) | 2007-05-03 | 2008-11-13 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| US8574567B2 (en) | 2007-05-03 | 2013-11-05 | The Brigham And Women's Hospital, Inc. | Multipotent stem cells and uses thereof |
| WO2008154033A2 (en) * | 2007-06-11 | 2008-12-18 | Symphony Medical, Inc. | Cardiac patterning for improving diastolic function |
| EP2203129A4 (en) * | 2007-10-15 | 2011-11-23 | Univ Wake Forest Health Sciences | METHOD AND COMPOSITIONS FOR PRINTING BIOCOMPATIBLE NANOROUS COMPOSITES FROM AUTOLOGOUS TISSUE |
| WO2009111755A2 (en) * | 2008-03-07 | 2009-09-11 | The Trustees Of Columbia University In The City Of New York | Compensating for atrioventricular block using a nucleic acid encoding a sodium channel or gap junction protein |
| CN106178118A (zh) | 2008-09-30 | 2016-12-07 | 加利福尼亚大学董事会 | 用于组织修复的使用细胞外基质的组合物和方法 |
| US20110091427A1 (en) * | 2009-10-02 | 2011-04-21 | Baxter International Inc. | Methods for treating a kidney injury |
| WO2012027514A2 (en) | 2010-08-24 | 2012-03-01 | The Regents Of The University Of California | Compositions and methods for cardiac therapy |
| EP2625263B1 (en) | 2010-10-08 | 2020-03-11 | Terumo BCT, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| WO2013036708A2 (en) | 2011-09-07 | 2013-03-14 | The Regents Of The University Of California | Compositions and methods for tissue repair with extracellular matrices |
| US20130216495A1 (en) | 2012-02-21 | 2013-08-22 | Baxter Healthcare Sa | Pharmaceutical composition comprising cd34+ cells |
| US10633625B2 (en) | 2013-11-16 | 2020-04-28 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
| JP2017505324A (ja) | 2014-02-07 | 2017-02-16 | ゴジョ・インダストリーズ・インコーポレイテッド | 胞子及び他の生物に対する効力を有する組成物及び方法 |
| CN106232800B (zh) | 2014-03-25 | 2020-07-03 | 泰尔茂比司特公司 | 介质的被动替代 |
| WO2016049421A1 (en) | 2014-09-26 | 2016-03-31 | Terumo Bct, Inc. | Scheduled feed |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| WO2017205667A1 (en) | 2016-05-25 | 2017-11-30 | Terumo Bct, Inc. | Cell expansion |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
| US12098385B2 (en) | 2017-09-20 | 2024-09-24 | The Regents Of The University Of California | Gene therapy strategy to restore cardiac electrical and structural function in arrhythmogenic right ventricular cardiomyopathy |
| IL273448B2 (en) * | 2017-09-20 | 2025-05-01 | Univ California | A gene therapy strategy to restore electrical and cardiac function, and cardiac structure, in arrhythmogenic right ventricular cardiomyopathy |
| JP7705950B2 (ja) | 2021-03-23 | 2025-07-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞を増殖する方法 |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5130141A (en) * | 1988-05-24 | 1992-07-14 | Law Peter K | Compositions for and methods of treating muscle degeneration and weakness |
| US5030204A (en) | 1988-09-28 | 1991-07-09 | Advanced Cardiovascular Systems, Inc. | Guiding catheter with controllable distal tip |
| WO1990010471A1 (en) | 1989-03-06 | 1990-09-20 | Angeion Corporation | Method of providing a biological pacemaker |
| US5103821A (en) * | 1989-03-06 | 1992-04-14 | Angeion Corporation | Method of providing a biological pacemaker |
| US5693622A (en) * | 1989-03-21 | 1997-12-02 | Vical Incorporated | Expression of exogenous polynucleotide sequences cardiac muscle of a mammal |
| US5087243A (en) | 1990-06-18 | 1992-02-11 | Boaz Avitall | Myocardial iontophoresis |
| US5661133B1 (en) * | 1991-11-12 | 1999-06-01 | Univ Michigan | Collateral blood vessel formation in cardiac muscle by injecting a dna sequence encoding an angiogenic protein |
| US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US5551426A (en) | 1993-07-14 | 1996-09-03 | Hummel; John D. | Intracardiac ablation and mapping catheter |
| US5602301A (en) * | 1993-11-16 | 1997-02-11 | Indiana University Foundation | Non-human mammal having a graft and methods of delivering protein to myocardial tissue |
| US5489294A (en) | 1994-02-01 | 1996-02-06 | Medtronic, Inc. | Steroid eluting stitch-in chronic cardiac lead |
| CA2183167A1 (en) | 1994-12-13 | 1996-06-20 | Peter K. Law | Myoblast therapy for mammalian diseases |
| US6129761A (en) * | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
| US5693029A (en) | 1995-07-10 | 1997-12-02 | World Medical Manufacturing Corporation | Pro-cell intra-cavity therapeutic agent delivery device |
| US6415178B1 (en) * | 1996-09-16 | 2002-07-02 | Impulse Dynamics N.V. | Fencing of cardiac muscles |
| AU2458597A (en) | 1996-07-17 | 1998-02-09 | Medtronic, Inc. | System for genetically treating cardiac conduction disturbances |
| CA2266033C (en) | 1996-09-10 | 2005-11-08 | Omrix Biopharmaceuticals S.A. | Applicator device for applying a multiple component fluid |
| US5722403A (en) | 1996-10-28 | 1998-03-03 | Ep Technologies, Inc. | Systems and methods using a porous electrode for ablating and visualizing interior tissue regions |
| US6059726A (en) * | 1996-11-08 | 2000-05-09 | The Regents Of The University Of California | Method for locating the atrio-ventricular (AV) junction of the heart and injecting active substances therein |
| US6239117B1 (en) * | 1997-02-13 | 2001-05-29 | Albert Einstein College Of Medicine Of Yeshiva University | Gene therapy for regulating bladder smooth muscle tone |
| US6271211B1 (en) * | 1997-02-13 | 2001-08-07 | Albert Einstein College Of Medicine Of Yeshiva University | Gene therapy for regulating penile smooth muscle tone |
| US6086582A (en) | 1997-03-13 | 2000-07-11 | Altman; Peter A. | Cardiac drug delivery system |
| US6110161A (en) * | 1997-04-03 | 2000-08-29 | Electrofect As | Method for introducing pharmaceutical drugs and nucleic acids into skeletal muscle |
| US6238429B1 (en) * | 1997-05-05 | 2001-05-29 | Medtronic, Inc. | Biologic cabling |
| EP1007631B2 (en) * | 1997-07-14 | 2009-02-18 | Osiris Therapeutics, Inc. | Cardiac muscle regeneration using mesenchymal stem cells |
| CA2225185A1 (en) * | 1997-08-11 | 1999-02-11 | Peter K. Law | Myoblast transfer therapy for relieving pain and for treating behavioral and perceptive abnormalities |
| EP1015042A1 (en) | 1997-09-19 | 2000-07-05 | Reprogenesis, Inc | Improved hydrogel for tissue engineering |
| US6151525A (en) * | 1997-11-07 | 2000-11-21 | Medtronic, Inc. | Method and system for myocardial identifier repair |
| EP1563866B1 (en) * | 1998-02-05 | 2007-10-03 | Biosense Webster, Inc. | Intracardiac drug delivery |
| US6360749B1 (en) | 1998-10-09 | 2002-03-26 | Swaminathan Jayaraman | Modification of properties and geometry of heart tissue to influence heart function |
| US20010009986A1 (en) * | 1999-02-23 | 2001-07-26 | Cordis Webster, Inc. | Steerable catheter for detecting and revascularizing ischemic myocardial tissue |
| WO2001066472A1 (en) | 2000-03-06 | 2001-09-13 | Tei Biosciences, Inc. | Injectable bio-compatible material and methods of use |
| IL151605A0 (en) | 2000-03-10 | 2003-04-10 | Advanced Res & Tech Inst | Cardiomyocyte cell populations, methods for obtaining the same and devices utilizing the same |
| DE10021627B4 (de) | 2000-05-04 | 2009-11-19 | Corlife Gbr (Vertretungsberechtigte Gesellschafter: Prof. Dr. Alex Haverich | Verfahren zur Herstellung eines vaskularisierten bioartifiziellen Gewebes und zugehöriger Versuchsreaktor |
| US20020001577A1 (en) * | 2000-06-30 | 2002-01-03 | Axel Haverich | Use of cells with the ability to generate excitation within a cell preparation |
| AU2001284695A1 (en) * | 2000-07-31 | 2002-02-13 | New York Medical College | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| AU2001288807B2 (en) | 2000-09-06 | 2007-07-19 | Johns Hopkins University | Cardiac arrhythmia treatment methods |
| US7294333B1 (en) | 2000-10-20 | 2007-11-13 | Genegrafts Ltd. | Nucleic acid constructs and cells, and methods utilizing same for modifying the electrophysiological function of excitable tissues |
| IL161862A0 (en) | 2001-11-08 | 2005-11-20 | Univ California | Methods and compositions for correction of cardiac conduction disturbances |
| EP1503716A4 (en) | 2002-05-08 | 2007-07-04 | Univ California | SYSTEM AND METHOD FOR THE TREATMENT OF CARDIAC ARCHITECTURES WITH FIBROBLASTED CELLS |
| WO2003094697A2 (en) | 2002-05-08 | 2003-11-20 | The Regents Of The University Of California | Methods and compositions for correction of cardiac conduction disturbances |
| US20040106896A1 (en) | 2002-11-29 | 2004-06-03 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| US6932804B2 (en) * | 2003-01-21 | 2005-08-23 | The Regents Of The University Of California | System and method for forming a non-ablative cardiac conduction block |
| JP2005524496A (ja) | 2002-05-08 | 2005-08-18 | ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア | 非破壊性心伝導ブロック形成用システム及び方法 |
| US7317950B2 (en) * | 2002-11-16 | 2008-01-08 | The Regents Of The University Of California | Cardiac stimulation system with delivery of conductive agent |
-
2002
- 2002-11-07 IL IL16186202A patent/IL161862A0/xx unknown
- 2002-11-07 BR BR0214018-7A patent/BR0214018A/pt not_active IP Right Cessation
- 2002-11-07 US US10/291,202 patent/US7252819B2/en not_active Expired - Fee Related
- 2002-11-07 CA CA002465476A patent/CA2465476A1/en not_active Abandoned
- 2002-11-07 WO PCT/US2002/035932 patent/WO2003039344A2/en not_active Ceased
- 2002-11-07 EP EP02793904A patent/EP1453382A4/en not_active Withdrawn
- 2002-11-07 JP JP2003541442A patent/JP2005527482A/ja not_active Withdrawn
- 2002-11-07 CN CNA028269055A patent/CN1612691A/zh active Pending
- 2002-11-07 AU AU2002359371A patent/AU2002359371A1/en not_active Abandoned
-
2004
- 2004-05-07 MX MXPA04004396A patent/MXPA04004396A/es unknown
-
2006
- 2006-12-05 US US11/635,810 patent/US7494644B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030104568A1 (en) | 2003-06-05 |
| WO2003039344A2 (en) | 2003-05-15 |
| CA2465476A1 (en) | 2003-05-15 |
| US7494644B2 (en) | 2009-02-24 |
| BR0214018A (pt) | 2005-04-19 |
| AU2002359371A1 (en) | 2003-05-19 |
| US7252819B2 (en) | 2007-08-07 |
| IL161862A0 (en) | 2005-11-20 |
| WO2003039344A3 (en) | 2003-12-31 |
| US20080019953A1 (en) | 2008-01-24 |
| JP2005527482A (ja) | 2005-09-15 |
| CN1612691A (zh) | 2005-05-04 |
| EP1453382A2 (en) | 2004-09-08 |
| EP1453382A4 (en) | 2005-05-18 |
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