BR0214017A - Polimorfismos de um único nucleotìdeo em gh-1 - Google Patents

Polimorfismos de um único nucleotìdeo em gh-1

Info

Publication number
BR0214017A
BR0214017A BR0214017-9A BR0214017A BR0214017A BR 0214017 A BR0214017 A BR 0214017A BR 0214017 A BR0214017 A BR 0214017A BR 0214017 A BR0214017 A BR 0214017A
Authority
BR
Brazil
Prior art keywords
single nucleotide
nucleotide polymorphisms
relates
polymorphisms
allele
Prior art date
Application number
BR0214017-9A
Other languages
English (en)
Inventor
Roger Francis Drong
Lars Allan Grundemar
Matthew Walter Kalnik
Louis Angel Parodi
Jerry Laverne Slightom
Susanne Diana Wagner
Linda Susan Wood
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BR0214017A publication Critical patent/BR0214017A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"POLIMORFISMOS DE UM úNICO NUCLEOTìDEO EM GH-1". A presente invenção refere-se a segmentos de ácido nucléico do gene de GH-1, incluindo sítios polimórficos. Também refere-se a iniciadores e sondas específicos para os alelos, que hibridizam com regiões flanqueadoras. A invenção também refere-se a métodos para diagnosticar disfunção de GH-1.
BR0214017-9A 2001-11-09 2002-11-07 Polimorfismos de um único nucleotìdeo em gh-1 BR0214017A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34744801P 2001-11-09 2001-11-09
PCT/US2002/035719 WO2003042226A2 (en) 2001-11-09 2002-11-07 Single nucleotide polymorphisms in gh-1

Publications (1)

Publication Number Publication Date
BR0214017A true BR0214017A (pt) 2005-01-04

Family

ID=23363738

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214017-9A BR0214017A (pt) 2001-11-09 2002-11-07 Polimorfismos de um único nucleotìdeo em gh-1

Country Status (8)

Country Link
US (1) US20030170679A1 (pt)
EP (1) EP1451368A4 (pt)
JP (1) JP2005508650A (pt)
AU (1) AU2002360349A1 (pt)
BR (1) BR0214017A (pt)
CA (1) CA2466346A1 (pt)
MX (1) MXPA04004291A (pt)
WO (1) WO2003042226A2 (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60332358D1 (de) * 2002-09-09 2010-06-10 Hanall Pharmaceutical Co Ltd Protease-resistente modifizierte interferon alpha polypeptide
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
GB0600114D0 (en) * 2006-01-05 2006-02-15 Univ Cardiff Growth hormone variations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE171185T1 (de) * 1985-03-15 1998-10-15 Antivirals Inc Immunotestmittel für polynukleotid und verfahren
US5185444A (en) * 1985-03-15 1993-02-09 Anti-Gene Deveopment Group Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
US5034506A (en) * 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5075217A (en) * 1989-04-21 1991-12-24 Marshfield Clinic Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
US5424186A (en) * 1989-06-07 1995-06-13 Affymax Technologies N.V. Very large scale immobilized polymer synthesis
DK1568772T3 (da) * 1995-09-21 2010-10-18 Genentech Inc Varianter af humant væksthormon
CA2197408A1 (en) * 1996-02-13 1997-08-14 Kazuo Chihara Mutant human growth hormones and their uses
US5856104A (en) * 1996-10-28 1999-01-05 Affymetrix, Inc. Polymorphisms in the glucose-6 phosphate dehydrogenase locus
US6946265B1 (en) * 1999-05-12 2005-09-20 Xencor, Inc. Nucleic acids and proteins with growth hormone activity

Also Published As

Publication number Publication date
AU2002360349A1 (en) 2003-05-26
WO2003042226A2 (en) 2003-05-22
EP1451368A4 (en) 2006-02-22
CA2466346A1 (en) 2003-05-22
EP1451368A2 (en) 2004-09-01
MXPA04004291A (es) 2004-08-11
WO2003042226A3 (en) 2004-03-18
JP2005508650A (ja) 2005-04-07
US20030170679A1 (en) 2003-09-11

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011.