BR0213291A - Composição e método para tratamento de diabetes - Google Patents
Composição e método para tratamento de diabetesInfo
- Publication number
- BR0213291A BR0213291A BR0213291-5A BR0213291A BR0213291A BR 0213291 A BR0213291 A BR 0213291A BR 0213291 A BR0213291 A BR 0213291A BR 0213291 A BR0213291 A BR 0213291A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- treating diabetes
- ingap
- formulation
- islet neogenesis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/474—Pancreatic thread protein; Reg protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4733—Acute pancreatitis-associated protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
"COMPOSIçãO E MéTODO PARA TRATAMENTO DE DIABETES". A presente invenção refere-se a regimes de dosagem e formulações de proteínas associadas à neogênese de ilhotas (INGAP ou "Islet NeoGenesis Associated Protein") e Peptídeo INGAP. A formulação aqui apresentada demonstrou ter estabilidade aceitável para uma composição farmacêutica. Além disso, a formulação é capaz de regenerar ilhotas funcionais.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32933001P | 2001-10-16 | 2001-10-16 | |
PCT/US2002/032904 WO2003033808A2 (en) | 2001-10-16 | 2002-10-15 | Composition and method for treating diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0213291A true BR0213291A (pt) | 2004-10-26 |
Family
ID=23284879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0213291-5A BR0213291A (pt) | 2001-10-16 | 2002-10-15 | Composição e método para tratamento de diabetes |
Country Status (20)
Country | Link |
---|---|
US (2) | US20040132644A1 (pt) |
EP (1) | EP1435995A2 (pt) |
JP (1) | JP2005506362A (pt) |
KR (1) | KR20050036865A (pt) |
CN (1) | CN1723034A (pt) |
BR (1) | BR0213291A (pt) |
CA (1) | CA2463769A1 (pt) |
CO (2) | CO5570658A2 (pt) |
CZ (1) | CZ2004479A3 (pt) |
HU (1) | HUP0401612A3 (pt) |
IL (1) | IL161073A0 (pt) |
MA (1) | MA27503A1 (pt) |
MX (1) | MXPA04003526A (pt) |
NO (1) | NO20042012L (pt) |
PE (1) | PE20030608A1 (pt) |
PL (1) | PL370069A1 (pt) |
RU (1) | RU2004114865A (pt) |
SK (1) | SK1702004A3 (pt) |
WO (1) | WO2003033808A2 (pt) |
ZA (1) | ZA200402261B (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2003275853A1 (en) * | 2002-10-24 | 2004-05-13 | Mcgill University | Use of ingap for reversing diabetes |
US20090142338A1 (en) * | 2005-03-04 | 2009-06-04 | Curedm, Inc. | Methods and Compositions for Treating Type 1 and Type 2 Diabetes Mellitus and Related Conditions |
WO2006096565A2 (en) * | 2005-03-04 | 2006-09-14 | Curedm Inc. | Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions |
JP2008545712A (ja) * | 2005-05-25 | 2008-12-18 | キュアーディーエム、インク. | ペプチド、その誘導体並びに類似体、及びそれらを使用する方法 |
EP1840573A1 (en) * | 2006-03-27 | 2007-10-03 | Institut Pasteur | Secreted proteins as early markers and drug targets for autoimmunity, tumorigenesis and infections |
WO2008064306A2 (en) * | 2006-11-22 | 2008-05-29 | Curedm, Inc. | Methods and compositions relating to islet cell neogenesis |
SI2193142T1 (sl) * | 2007-08-30 | 2015-05-29 | Curedm Group Holdings, Llc | Sestavek in postopek za uporabo proislet peptidov in analogov le-teh |
CA2886442A1 (en) * | 2012-09-27 | 2014-04-03 | Claresa LEVETAN | Generation of new pancreatic beta cells |
CN104045702A (zh) * | 2013-03-15 | 2014-09-17 | 深圳君圣泰生物技术有限公司 | 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物 |
WO2014139182A1 (en) * | 2013-03-15 | 2014-09-18 | Shenzhen Hightide Biopharmaceutical, Ltd. | Compositions and methods of using islet neogenesis peptides and analogs thereof |
CN104045699A (zh) * | 2013-03-15 | 2014-09-17 | 深圳君圣泰生物技术有限公司 | 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物 |
CN104045698B (zh) * | 2013-03-15 | 2019-04-16 | 深圳君圣泰生物技术有限公司 | 一种多肽、多肽衍生物、多肽的可药用盐及药物组合物 |
CN103305457B (zh) * | 2013-06-06 | 2015-07-08 | 浙江省医学科学院 | 一种体外扩增胰岛β细胞的方法 |
US20160039876A1 (en) * | 2014-03-28 | 2016-02-11 | Claresa Levetan | Insulin independence among patients with diabetes utilizing an optimized hamster reg3 gamma peptide |
CN109195983B (zh) * | 2016-03-10 | 2022-05-17 | 深圳君圣泰生物技术有限公司 | 胰岛新生多肽和类似物的缀合物及其方法 |
US20210196646A1 (en) * | 2018-08-15 | 2021-07-01 | Wake Forest University Health Sciences | Improved formulations for pancreatic islet encapsulation |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US127624A (en) * | 1872-06-04 | Improvement in apparatus for elevating water | ||
US4658957A (en) * | 1985-01-28 | 1987-04-21 | Abbott Laboratories | Utility tray |
US6106840A (en) * | 1988-06-23 | 2000-08-22 | Anergen, Inc. | MHC conjugates useful in ameliorating autoimmunity |
US5834590A (en) * | 1995-02-22 | 1998-11-10 | Eastern Virginia Medical School Of The Medical College Of Hampton Roads | Ingap protein involved in pancreatic islet neogenesis |
JP4111539B2 (ja) * | 1995-02-22 | 2008-07-02 | イースタン・ヴァージニア・メディカル・スクール・オブ・ザ・メディカル・カレッジ・オブ・ハンプトン・ローズ | 膵島新生に関与するingapタンパク質 |
DK0910571T3 (da) * | 1996-05-03 | 2005-10-31 | Abbott Lab | Hidtil ukendte antiangiogene peptider, polynucleotider, der koder for samme, samt fremgangsmåder til inhibering af angiogenese |
US6090577A (en) * | 1997-05-22 | 2000-07-18 | Incyte Pharmaceuticals, Inc. | Disease associated acidic protein |
US6986994B2 (en) * | 2001-01-09 | 2006-01-17 | Gmp Endotherapeutics, Inc. | INGAP displacement assays |
-
2002
- 2002-09-24 US US10/253,733 patent/US20040132644A1/en not_active Abandoned
- 2002-10-15 HU HU0401612A patent/HUP0401612A3/hu unknown
- 2002-10-15 PL PL02370069A patent/PL370069A1/xx not_active Application Discontinuation
- 2002-10-15 CA CA002463769A patent/CA2463769A1/en not_active Abandoned
- 2002-10-15 EP EP02780465A patent/EP1435995A2/en not_active Ceased
- 2002-10-15 PE PE2002001014A patent/PE20030608A1/es not_active Application Discontinuation
- 2002-10-15 SK SK170-2004A patent/SK1702004A3/sk not_active Application Discontinuation
- 2002-10-15 CN CNA028201922A patent/CN1723034A/zh active Pending
- 2002-10-15 MX MXPA04003526A patent/MXPA04003526A/es unknown
- 2002-10-15 KR KR1020047005586A patent/KR20050036865A/ko not_active Application Discontinuation
- 2002-10-15 WO PCT/US2002/032904 patent/WO2003033808A2/en not_active Application Discontinuation
- 2002-10-15 CZ CZ2004479A patent/CZ2004479A3/cs unknown
- 2002-10-15 IL IL16107302A patent/IL161073A0/xx unknown
- 2002-10-15 BR BR0213291-5A patent/BR0213291A/pt not_active IP Right Cessation
- 2002-10-15 JP JP2003536523A patent/JP2005506362A/ja active Pending
- 2002-10-15 RU RU2004114865/15A patent/RU2004114865A/ru not_active Application Discontinuation
-
2004
- 2004-03-23 ZA ZA200402261A patent/ZA200402261B/en unknown
- 2004-04-02 CO CO04031543A patent/CO5570658A2/es not_active Application Discontinuation
- 2004-04-09 MA MA27627A patent/MA27503A1/fr unknown
- 2004-05-14 NO NO20042012A patent/NO20042012L/no not_active Application Discontinuation
- 2004-06-25 CO CO04060289A patent/CO5590933A2/es not_active Application Discontinuation
-
2007
- 2007-12-04 US US11/999,208 patent/US20080171704A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PL370069A1 (en) | 2005-05-16 |
US20040132644A1 (en) | 2004-07-08 |
CA2463769A1 (en) | 2003-04-24 |
HUP0401612A3 (en) | 2006-04-28 |
IL161073A0 (en) | 2004-08-31 |
WO2003033808A2 (en) | 2003-04-24 |
CN1723034A (zh) | 2006-01-18 |
CO5590933A2 (es) | 2005-12-30 |
RU2004114865A (ru) | 2005-05-27 |
CO5570658A2 (es) | 2005-10-31 |
NO20042012L (no) | 2004-07-16 |
US20080171704A1 (en) | 2008-07-17 |
EP1435995A2 (en) | 2004-07-14 |
KR20050036865A (ko) | 2005-04-20 |
MA27503A1 (fr) | 2005-09-01 |
PE20030608A1 (es) | 2003-08-26 |
JP2005506362A (ja) | 2005-03-03 |
ZA200402261B (en) | 2004-09-28 |
MXPA04003526A (es) | 2004-07-22 |
HUP0401612A2 (hu) | 2004-12-28 |
WO2003033808A3 (en) | 2003-09-18 |
SK1702004A3 (sk) | 2005-03-04 |
CZ2004479A3 (cs) | 2005-01-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 4A., 5A., 6A. E 7A. ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2034 DE 29/12/2009. |