BR0211563A - Modelo de infecção por mycoplasma bovis e métodos para administração de m. bovis e para indução de lesões pneumÈnicas do pulmão - Google Patents
Modelo de infecção por mycoplasma bovis e métodos para administração de m. bovis e para indução de lesões pneumÈnicas do pulmãoInfo
- Publication number
- BR0211563A BR0211563A BR0211563-8A BR0211563A BR0211563A BR 0211563 A BR0211563 A BR 0211563A BR 0211563 A BR0211563 A BR 0211563A BR 0211563 A BR0211563 A BR 0211563A
- Authority
- BR
- Brazil
- Prior art keywords
- bovis
- methods
- induction
- administration
- infection
- Prior art date
Links
- 241001138504 Mycoplasma bovis Species 0.000 title abstract 7
- 208000015181 infectious disease Diseases 0.000 title abstract 6
- 230000006698 induction Effects 0.000 title abstract 2
- 210000004072 lung Anatomy 0.000 title abstract 2
- 230000003902 lesion Effects 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000001413 cellular effect Effects 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56933—Mycoplasma
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/101—Bovine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0337—Animal models for infectious diseases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/30—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycoplasmatales, e.g. Pleuropneumonia-like organisms [PPLO]
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2469/00—Immunoassays for the detection of microorganisms
- G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Animal Behavior & Ethology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Toxicology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biodiversity & Conservation Biology (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
Abstract
"MODELO DE INFECçãO POR MYCOPLASMA BOVIS E MéTODOS PARA ADMINISTRAçãO DE M. BOVIS E PARA INDUçãO DE LESõES PNEUMÈNICAS DO PULMãO". A presente invenção proporciona um modelo de infecção experimental reprodutível, por M. bovis e métodos para a indução e estabelecimento, de forma confiável, de uma doença ou alteração causada pela infecção por M. bovis, através da administração a um animal de uma quantidade eficaz de uma cultura de M. bovis. A cultura para infecção experimental da presente invenção é administrada em uma quantidade suficiente para induzir respostas imunes específicas celulares ou humorais. O modelo de infecção experimental por M. bovis de acordo com o presente invenção pode ser usado para avaliar a eficácia de vacinas em potencial.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31532401P | 2001-08-28 | 2001-08-28 | |
PCT/IB2002/003074 WO2003017755A2 (en) | 2001-08-28 | 2002-07-25 | Mycoplasma bovis challenge model, methods for administering m.bovis and methods for inducing pneumonic lung lesions |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0211563A true BR0211563A (pt) | 2004-07-13 |
Family
ID=23223885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0211563-8A BR0211563A (pt) | 2001-08-28 | 2002-07-25 | Modelo de infecção por mycoplasma bovis e métodos para administração de m. bovis e para indução de lesões pneumÈnicas do pulmão |
Country Status (15)
Country | Link |
---|---|
US (1) | US20030180219A1 (pt) |
EP (1) | EP1420636A2 (pt) |
JP (1) | JP2005500845A (pt) |
KR (1) | KR20040031015A (pt) |
CN (1) | CN1571633A (pt) |
AR (1) | AR036355A1 (pt) |
BR (1) | BR0211563A (pt) |
CA (1) | CA2457514A1 (pt) |
HU (1) | HUP0401077A3 (pt) |
IL (1) | IL159145A0 (pt) |
MX (1) | MXPA04001872A (pt) |
PL (1) | PL368826A1 (pt) |
RU (1) | RU2004105962A (pt) |
WO (1) | WO2003017755A2 (pt) |
ZA (1) | ZA200309625B (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008030619A2 (en) * | 2006-09-07 | 2008-03-13 | Boehringer Ingelheim Vetmedica, Inc. | Pcr-based genotyping |
UY31437A1 (es) | 2007-10-29 | 2009-05-29 | Vacuna de mycoplasma bovis y métodos de uso de la misma | |
AU2012258478B2 (en) * | 2008-06-27 | 2013-10-03 | Zoetis Services Llc | Novel adjuvant compositions |
ES2728949T3 (es) | 2008-06-27 | 2019-10-29 | Zoetis Services Llc | Composiciones adyuvantes novedosas |
EP2362780B1 (en) | 2008-10-31 | 2019-12-25 | Boehringer Ingelheim Animal Health USA Inc. | Use of various antigens including antigens from mycoplasma bovis in multivalent vaccine composition |
UY32570A (es) | 2009-04-24 | 2010-11-30 | Boehringer Ingelheim Vetmed | Vacuna viva modificada de mycoplasma bovis mejorada |
CN104968365B (zh) | 2012-12-28 | 2018-04-03 | 勃林格殷格翰动物保健有限公司 | 支原体疫苗的制备方法 |
AU2014321369B2 (en) | 2013-09-19 | 2020-04-16 | Zoetis Services Llc | Oil-based adjuvants |
WO2016115456A1 (en) | 2015-01-16 | 2016-07-21 | Zoetis Services Llc | Foot-and-mouth disease vaccine |
CN109022314B (zh) * | 2018-08-06 | 2021-08-13 | 北京华夏兴洋生物科技有限公司 | 一株牛支原体及其在疫苗研制中的应用 |
CN109833333A (zh) * | 2019-02-16 | 2019-06-04 | 首都医科大学附属北京中医医院 | 一种制备肺炎大鼠模型的方法及模型评价方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1229929A2 (en) * | 1999-11-08 | 2002-08-14 | Biomune | VACCINES FOR i MYCOPLASMA BOVIS /i AND METHODS OF USE |
JP2004537543A (ja) * | 2001-07-02 | 2004-12-16 | ファイザー・プロダクツ・インク | マイコプラズマ・ハイオニューモニエ・ワクチンおよび牛におけるマイコプラズマ・ボビス低減方法 |
-
2002
- 2002-07-25 JP JP2003522292A patent/JP2005500845A/ja not_active Withdrawn
- 2002-07-25 IL IL15914502A patent/IL159145A0/xx unknown
- 2002-07-25 CA CA002457514A patent/CA2457514A1/en not_active Abandoned
- 2002-07-25 CN CNA028203852A patent/CN1571633A/zh active Pending
- 2002-07-25 RU RU2004105962/13A patent/RU2004105962A/ru not_active Application Discontinuation
- 2002-07-25 PL PL02368826A patent/PL368826A1/xx unknown
- 2002-07-25 BR BR0211563-8A patent/BR0211563A/pt not_active IP Right Cessation
- 2002-07-25 WO PCT/IB2002/003074 patent/WO2003017755A2/en not_active Application Discontinuation
- 2002-07-25 EP EP02753169A patent/EP1420636A2/en not_active Withdrawn
- 2002-07-25 KR KR10-2004-7002886A patent/KR20040031015A/ko not_active Application Discontinuation
- 2002-07-25 MX MXPA04001872A patent/MXPA04001872A/es not_active Application Discontinuation
- 2002-07-25 HU HU0401077A patent/HUP0401077A3/hu unknown
- 2002-08-26 US US10/227,730 patent/US20030180219A1/en not_active Abandoned
- 2002-08-26 AR ARP020103190A patent/AR036355A1/es unknown
-
2003
- 2003-12-11 ZA ZA200309625A patent/ZA200309625B/en unknown
Also Published As
Publication number | Publication date |
---|---|
IL159145A0 (en) | 2004-06-01 |
WO2003017755A2 (en) | 2003-03-06 |
HUP0401077A2 (hu) | 2004-08-30 |
MXPA04001872A (es) | 2004-06-15 |
HUP0401077A3 (en) | 2004-10-28 |
EP1420636A2 (en) | 2004-05-26 |
AR036355A1 (es) | 2004-09-01 |
RU2004105962A (ru) | 2005-03-27 |
JP2005500845A (ja) | 2005-01-13 |
PL368826A1 (en) | 2005-04-04 |
KR20040031015A (ko) | 2004-04-09 |
CA2457514A1 (en) | 2003-03-06 |
US20030180219A1 (en) | 2003-09-25 |
CN1571633A (zh) | 2005-01-26 |
WO2003017755A3 (en) | 2003-10-23 |
ZA200309625B (en) | 2004-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 5A., 6A., E 7A. ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009. |