BR0211338A - G protein coupled receiver, gave8 - Google Patents

G protein coupled receiver, gave8

Info

Publication number
BR0211338A
BR0211338A BR0211338-4A BR0211338A BR0211338A BR 0211338 A BR0211338 A BR 0211338A BR 0211338 A BR0211338 A BR 0211338A BR 0211338 A BR0211338 A BR 0211338A
Authority
BR
Brazil
Prior art keywords
gave8
nucleic acid
protein
expression vectors
coupled receiver
Prior art date
Application number
BR0211338-4A
Other languages
Portuguese (pt)
Inventor
Haifeng Eishingdrelo
Jidong Cai
Ali Ardati
Anthony Sandrasagra
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0125704.7A external-priority patent/GB0125704D0/en
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of BR0211338A publication Critical patent/BR0211338A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

"RECEPTOR ACOPLADO à PROTEìNA G, GAVE8". A presente invenção refere-se a moléculas de polipeptídeos, proteínas e ácidos nucléicos de GAVE8. Em adição às proteínas GAVE8 de comprimento completo isoladas, são fornecidas proteínas de fusão, peptídeos antigênicos e anti-GAVE8 isolados. A invenção refere-se ainda a moléculas de ácido nucléico de GAVE8, vetores de expressão recombinantes contendo a molécula de ácido nucléico, células hospedeiras nas quais os vetores de expressão foram introduzidos e são descritos animais transgênicos não-humanos nos quais o gene GAVE8 foi introduzido ou interrompido. São também fornecidos processos para diagnóstico, seleção e terapêuticos utilizando composições de GAVE8 ou moléculas que se ligam a GAVE8. São descritos os processos para a identificação de agonistas, antagonistas, agonistas inversos de GAVE8 e similares."PROTEIN G-COUPLED RECEIVER, GAVE8". The present invention relates to GAVE8 polypeptide, protein and nucleic acid molecules. In addition to the isolated full length GAVE8 proteins, isolated fusion proteins, antigenic and anti-GAVE8 peptides are provided. The invention further relates to GAVE8 nucleic acid molecules, recombinant expression vectors containing the nucleic acid molecule, host cells into which expression vectors have been introduced and non-human transgenic animals into which the GAVE8 gene was introduced. or interrupted. Diagnostic, selection and therapeutic methods are also provided using GAVE8 compositions or GAVE8 binding molecules. Methods for identifying GAVE8 agonists, antagonists, inverse agonists and the like are described.

BR0211338-4A 2001-07-20 2002-07-19 G protein coupled receiver, gave8 BR0211338A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30643401P 2001-07-20 2001-07-20
GBGB0125704.7A GB0125704D0 (en) 2001-07-20 2001-10-26 A novel g protein-coupled receptor gaves
PCT/US2002/023208 WO2003008560A2 (en) 2001-07-20 2002-07-19 A novel g protein-coupled receptor, gave8

Publications (1)

Publication Number Publication Date
BR0211338A true BR0211338A (en) 2004-11-16

Family

ID=26246697

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211338-4A BR0211338A (en) 2001-07-20 2002-07-19 G protein coupled receiver, gave8

Country Status (9)

Country Link
EP (1) EP1448583A4 (en)
JP (1) JP2005522184A (en)
BR (1) BR0211338A (en)
CA (1) CA2454427A1 (en)
IL (1) IL159939A0 (en)
MX (1) MXPA04000437A (en)
NO (1) NO20040252L (en)
TW (1) TWI250209B (en)
WO (1) WO2003008560A2 (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
ATE364697T1 (en) * 2000-04-26 2007-07-15 Sanofi Aventis Deutschland EDG8 RECEPTOR, ITS PRODUCTION AND USE
WO2002000719A2 (en) * 2000-06-23 2002-01-03 Tularik Inc. Human and mouse g-protein couipled receptors

Also Published As

Publication number Publication date
CA2454427A1 (en) 2003-01-30
WO2003008560A2 (en) 2003-01-30
EP1448583A2 (en) 2004-08-25
NO20040252L (en) 2004-03-19
MXPA04000437A (en) 2004-03-18
EP1448583A4 (en) 2006-02-08
TWI250209B (en) 2006-03-01
IL159939A0 (en) 2004-06-20
WO2003008560A8 (en) 2004-06-24
JP2005522184A (en) 2005-07-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A,7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2060 DE 29/06/2010.