EP1448583A4 - A novel g protein-coupled receptor, gave8 - Google Patents

A novel g protein-coupled receptor, gave8

Info

Publication number
EP1448583A4
EP1448583A4 EP02747073A EP02747073A EP1448583A4 EP 1448583 A4 EP1448583 A4 EP 1448583A4 EP 02747073 A EP02747073 A EP 02747073A EP 02747073 A EP02747073 A EP 02747073A EP 1448583 A4 EP1448583 A4 EP 1448583A4
Authority
EP
European Patent Office
Prior art keywords
gave8
protein
novel
coupled receptor
receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02747073A
Other languages
German (de)
French (fr)
Other versions
EP1448583A2 (en
Inventor
Haifeng Eishingdrelo
Jidong Cai
Ali Ardati
Anthony Sandrasagra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Aventis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0125704.7A external-priority patent/GB0125704D0/en
Application filed by Aventis Pharmaceuticals Inc filed Critical Aventis Pharmaceuticals Inc
Publication of EP1448583A2 publication Critical patent/EP1448583A2/en
Publication of EP1448583A4 publication Critical patent/EP1448583A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP02747073A 2001-07-20 2002-07-19 A novel g protein-coupled receptor, gave8 Withdrawn EP1448583A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US30643401P 2001-07-20 2001-07-20
US306434P 2001-07-20
GB0125704 2001-10-26
GBGB0125704.7A GB0125704D0 (en) 2001-07-20 2001-10-26 A novel g protein-coupled receptor gaves
PCT/US2002/023208 WO2003008560A2 (en) 2001-07-20 2002-07-19 A novel g protein-coupled receptor, gave8

Publications (2)

Publication Number Publication Date
EP1448583A2 EP1448583A2 (en) 2004-08-25
EP1448583A4 true EP1448583A4 (en) 2006-02-08

Family

ID=26246697

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02747073A Withdrawn EP1448583A4 (en) 2001-07-20 2002-07-19 A novel g protein-coupled receptor, gave8

Country Status (9)

Country Link
EP (1) EP1448583A4 (en)
JP (1) JP2005522184A (en)
BR (1) BR0211338A (en)
CA (1) CA2454427A1 (en)
IL (1) IL159939A0 (en)
MX (1) MXPA04000437A (en)
NO (1) NO20040252L (en)
TW (1) TWI250209B (en)
WO (1) WO2003008560A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001081573A1 (en) * 2000-04-26 2001-11-01 Aventis Pharma Deutschland Gmbh Edg8 receptor, its preparation and use
WO2002000719A2 (en) * 2000-06-23 2002-01-03 Tularik Inc. Human and mouse g-protein couipled receptors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036473A2 (en) * 1999-11-16 2001-05-25 Pharmacia & Upjohn Company Human g protein-coupled receptors
WO2001081573A1 (en) * 2000-04-26 2001-11-01 Aventis Pharma Deutschland Gmbh Edg8 receptor, its preparation and use
WO2002000719A2 (en) * 2000-06-23 2002-01-03 Tularik Inc. Human and mouse g-protein couipled receptors

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 6 December 2000 (2000-12-06), "Homo sapiens sphingosine 1-phosphate receptor Edg-8 gene, complete cds.", XP002357167, retrieved from EBI accession no. EM_PRO:AF317676 Database accession no. AF317676 *
DATABASE Geneseq [online] 25 February 2002 (2002-02-25), "Human EDG8 receptor protein.", XP002357169, retrieved from EBI accession no. GSN:AAG80590 Database accession no. AAG80590 *
DATABASE Geneseq [online] 25 February 2002 (2002-02-25), "Human EDG-8 receptor protein.", XP002357215, retrieved from EBI accession no. GSN:AAG80582 Database accession no. AAG80582 *
DATABASE Geneseq [online] 28 August 2001 (2001-08-28), "Human nGPCR9 #2.", XP002357168, retrieved from EBI accession no. GSN:AAG80967 Database accession no. AAG80967 *
DATABASE Geneseq [online] 9 April 2002 (2002-04-09), "Amino acid sequence of human G-protein coupled receptor edg protein.", XP002357214, retrieved from EBI accession no. GSN:AAU74910 Database accession no. AAU74910 *
GOETZL E J ET AL: "A SUBFAMILY OF G PROTEIN-COUPLED CELLULAR RECEPTORS FOR LYSOPHOSPHOLIPIDS AND LYSOSPHINGOLIPIDS", ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, SPRING ST., NY, US, vol. 469, 1999, pages 259 - 264, XP002944908, ISSN: 0065-2598 *
LIU C H ET AL: "The Mouse Gene for the Inducible G-Protein-Coupled Receptoredg-1", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 43, no. 1, 1 July 1997 (1997-07-01), pages 15 - 24, XP004459267, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
MXPA04000437A (en) 2004-03-18
WO2003008560A8 (en) 2004-06-24
IL159939A0 (en) 2004-06-20
WO2003008560A2 (en) 2003-01-30
CA2454427A1 (en) 2003-01-30
EP1448583A2 (en) 2004-08-25
JP2005522184A (en) 2005-07-28
NO20040252L (en) 2004-03-19
BR0211338A (en) 2004-11-16
TWI250209B (en) 2006-03-01

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Legal Events

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Ipc: A61K 35/00 20060101ALI20051214BHEP

Ipc: G01N 33/50 20060101ALI20051214BHEP

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Ipc: C12N 15/12 20060101ALI20051214BHEP

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