BR0210831A - Moléculas ligantes imunológicas que inibem a fusão sincicial de células trofoblastos - Google Patents

Moléculas ligantes imunológicas que inibem a fusão sincicial de células trofoblastos

Info

Publication number
BR0210831A
BR0210831A BR0210831-3A BR0210831A BR0210831A BR 0210831 A BR0210831 A BR 0210831A BR 0210831 A BR0210831 A BR 0210831A BR 0210831 A BR0210831 A BR 0210831A
Authority
BR
Brazil
Prior art keywords
ligand molecules
trophoblast cells
fusion
inhibit
immunological ligand
Prior art date
Application number
BR0210831-3A
Other languages
English (en)
Inventor
Hans-Georg Frank
Peter Kaufmann
Ulrike Schmitz
Original Assignee
Aplagen Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aplagen Gmbh filed Critical Aplagen Gmbh
Publication of BR0210831A publication Critical patent/BR0210831A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

"MOLéCULAS LIGANTES IMUNOLóGICAS QUE INIBEM A FUSãO SINCICIAL DE CéLULAS TROFOBLASTOS". A presente invenção refere-se a uma proteína que é homóloga com VL ou VH de galinha pelo menos 80% e inibe fusão sincicial, assim como fragmentos tendo pelo menos 12 aminoácidos contínuos a partir da seq³ência de VL ou VH de galinha.
BR0210831-3A 2001-07-04 2002-07-03 Moléculas ligantes imunológicas que inibem a fusão sincicial de células trofoblastos BR0210831A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01116199 2001-07-04
PCT/EP2002/007359 WO2003004533A1 (de) 2001-07-04 2002-07-03 Immunologische bindungsmoleküle, die die synzytiale fusion von trophoblastzellen hemmen

Publications (1)

Publication Number Publication Date
BR0210831A true BR0210831A (pt) 2004-06-22

Family

ID=8177934

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0210831-3A BR0210831A (pt) 2001-07-04 2002-07-03 Moléculas ligantes imunológicas que inibem a fusão sincicial de células trofoblastos

Country Status (18)

Country Link
US (1) US20050048628A1 (pt)
EP (1) EP1401871B1 (pt)
JP (1) JP2005504525A (pt)
CN (1) CN1656120A (pt)
AT (1) ATE291589T1 (pt)
BR (1) BR0210831A (pt)
CA (1) CA2453042A1 (pt)
DE (1) DE50202554D1 (pt)
DK (1) DK1401871T3 (pt)
ES (1) ES2237703T3 (pt)
HU (1) HU224694B1 (pt)
IL (1) IL159384A0 (pt)
MX (1) MXPA03011812A (pt)
PT (1) PT1401871E (pt)
RU (1) RU2004103078A (pt)
SI (1) SI1401871T1 (pt)
WO (1) WO2003004533A1 (pt)
ZA (1) ZA200400054B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526433B (zh) * 2012-01-31 2013-06-05 赵海霞 一种治疗关节挛缩的药物
WO2021202013A1 (en) * 2020-03-30 2021-10-07 Crystal Bioscience Inc. Anti-gipr antibody and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006857A1 (en) * 1991-09-30 1993-04-15 Flinders Technologies Pty. Ltd. Preparation and use of human trophoblast membrane expressed protein in an anti-fertility vaccine
AU781486B2 (en) * 1999-12-30 2005-05-26 Aplagen Gmbh Method for identifying substances which mimic mammal epitopes

Also Published As

Publication number Publication date
SI1401871T1 (pt) 2005-08-31
MXPA03011812A (es) 2005-03-07
EP1401871B1 (de) 2005-03-23
DE50202554D1 (de) 2005-04-28
CN1656120A (zh) 2005-08-17
ATE291589T1 (de) 2005-04-15
PT1401871E (pt) 2005-05-31
RU2004103078A (ru) 2005-07-10
HU224694B1 (en) 2006-01-30
HUP0400839A2 (en) 2004-07-28
DK1401871T3 (da) 2005-08-01
ES2237703T3 (es) 2005-08-01
JP2005504525A (ja) 2005-02-17
EP1401871A1 (de) 2004-03-31
IL159384A0 (en) 2004-06-01
CA2453042A1 (en) 2003-01-16
US20050048628A1 (en) 2005-03-03
WO2003004533A1 (de) 2003-01-16
ZA200400054B (en) 2004-10-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A,6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.