BR0210697A - Methods and compositions useful for predicting blood-brain barrier permeation - Google Patents
Methods and compositions useful for predicting blood-brain barrier permeationInfo
- Publication number
- BR0210697A BR0210697A BR0210697-3A BR0210697A BR0210697A BR 0210697 A BR0210697 A BR 0210697A BR 0210697 A BR0210697 A BR 0210697A BR 0210697 A BR0210697 A BR 0210697A
- Authority
- BR
- Brazil
- Prior art keywords
- brain barrier
- methods
- compositions useful
- barrier permeation
- predicting blood
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
Abstract
"MéTODOS E COMPOSIçõES úTEIS PARA A PREVISãO DA PERMEAçãO DA BARREIRA SANGUE-CéREBRO". A presente invenção provê um método para a determinação in vitro da habilidade de um composto ou uma mistura de compostos em permear a barreira sangue-cérebro e uma composição de membrana útil para isso."METHODS AND USEFUL COMPOSITIONS FOR FORECASTING BLOOD-BRAIN BARRIER EXCHANGE". The present invention provides a method for determining in vitro the ability of a compound or mixture of compounds to permeate the blood-brain barrier and a membrane composition useful therefor.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30208501P | 2001-06-29 | 2001-06-29 | |
PCT/US2002/019736 WO2003003007A2 (en) | 2001-06-29 | 2002-06-20 | Methods and compositions useful for the prediction of blood-brain barrier permeation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0210697A true BR0210697A (en) | 2004-09-21 |
Family
ID=23166189
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0210697-3A BR0210697A (en) | 2001-06-29 | 2002-06-20 | Methods and compositions useful for predicting blood-brain barrier permeation |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP1399539A2 (en) |
JP (1) | JP2005501230A (en) |
AR (1) | AR036121A1 (en) |
AU (1) | AU2002315398A1 (en) |
BR (1) | BR0210697A (en) |
CA (1) | CA2448746A1 (en) |
MX (1) | MXPA03011439A (en) |
WO (1) | WO2003003007A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE453119T1 (en) | 2002-01-31 | 2010-01-15 | Pion Inc | METHOD AND DEVICE FOR MEASURING MEMBRANE PERMEABILITY |
US8986781B2 (en) * | 2005-10-27 | 2015-03-24 | Corning Incorporated | Immobilized multi-layer artificial membrane for permeability measurements (PAMPA) |
DE102008007673A1 (en) * | 2008-01-25 | 2009-07-30 | Nimbus Biotechnologie Gmbh | Determination of the permeability of substances through the blood-brain barrier |
US10143187B2 (en) | 2017-02-17 | 2018-12-04 | Denali Therapeutics Inc. | Transferrin receptor transgenic models |
US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
AU2018221731C1 (en) | 2017-02-17 | 2021-11-18 | Denali Therapeutics Inc. | Engineered transferrin receptor binding polypeptides |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260210A (en) * | 1989-09-27 | 1993-11-09 | Rubin Lee L | Blood-brain barrier model |
-
2002
- 2002-06-20 WO PCT/US2002/019736 patent/WO2003003007A2/en not_active Application Discontinuation
- 2002-06-20 BR BR0210697-3A patent/BR0210697A/en not_active Application Discontinuation
- 2002-06-20 EP EP02742248A patent/EP1399539A2/en not_active Withdrawn
- 2002-06-20 MX MXPA03011439A patent/MXPA03011439A/en unknown
- 2002-06-20 JP JP2003509140A patent/JP2005501230A/en active Pending
- 2002-06-20 CA CA002448746A patent/CA2448746A1/en not_active Abandoned
- 2002-06-20 AU AU2002315398A patent/AU2002315398A1/en not_active Abandoned
- 2002-06-28 AR ARP020102434 patent/AR036121A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1399539A2 (en) | 2004-03-24 |
JP2005501230A (en) | 2005-01-13 |
CA2448746A1 (en) | 2003-01-09 |
MXPA03011439A (en) | 2004-04-05 |
WO2003003007A2 (en) | 2003-01-09 |
WO2003003007A3 (en) | 2003-05-22 |
AR036121A1 (en) | 2004-08-11 |
AU2002315398A1 (en) | 2003-03-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0213207A (en) | peptide remodeling and glycoconjugation | |
ECSP055910A (en) | NEW CARBOXILIC ACIDS AND ITS ESTERS, MEDICATIONS CONTAINING THESE COMPOUNDS AND PROCEDURES FOR THEIR PREPARATION | |
BRPI0410630A (en) | nk1 antagonist | |
BRPI0412321A (en) | cleaning peroxide filtration membranes | |
BR0213612A (en) | Compound, pharmaceutical composition, use of compound and method for treating disease or condition | |
BRPI0715579A2 (en) | "compound, pharmaceutical composition and use of a compound" | |
NO20055652L (en) | Lactate-containing pharmaceutical preparation and its use | |
DE602004021786D1 (en) | TETRAHYDROISOCHINOLYLACETAMIDE DERIVATIVES FOR USE AS OREXINE RECEPTOR ANTAGONISTS | |
BR0211723A (en) | Corineform bacteria that produce chemical compounds i | |
NO20051102L (en) | Sulfonylamino-acetic acid derivatives | |
ECSP034850A (en) | SALT CITRATE OF 5, 8, 14-TRIAZATETRACICLO [10.3.1.02,11.04,9] HEXADECA-2 (11), 3,5,7,9-PENTAENO AND PHARMACEUTICAL COMPOSITIONS OF THE SAME | |
IS2648B (en) | Amino cyclohexyl ether compounds and their use | |
DK1436257T3 (en) | Oxime analogs of 1-alpha, 25-dihydroxy-vitamin-D3 with low calcium effect | |
BR0206293A (en) | Immunization Compositions and Methods of Use | |
BR0215148A (en) | 5ht4 Partial Agonist Pharmaceutical Compositions | |
UY26057A1 (en) | MODIFIED AMINO ACID AMIDES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCEDURE FOR THEIR PREPARATION | |
BRPI0609765A8 (en) | isoalkane mixture, method for the preparation thereof, cosmetic or pharmaceutical composition, and use of an isoalkane mixture | |
BR0100982A (en) | Process for the preparation of deresorcinol derivatives | |
BR9909468A (en) | Anti-bacterial compound, oral anti-plaque composition, and, process for promoting oral hygiene | |
BR0210697A (en) | Methods and compositions useful for predicting blood-brain barrier permeation | |
ATE430160T1 (en) | LIPOPEPTIDE STEREOISOMERS, METHOD FOR THE PRODUCTION THEREOF AND USEFUL INTERMEDIATE PRODUCTS | |
MY138542A (en) | Biguanide and dihydrotriazine derivatives | |
BR0212353A (en) | Compound, pharmaceutical composition, and use of a compound | |
BR0317229A (en) | Composition and use of alfa7nachr complete agonist | |
BR0315178A (en) | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |