BR0205410A - N-(ciclopropilmetil) aza cicloalcanos, composições contendo os mesmos e processos de preparação - Google Patents

N-(ciclopropilmetil) aza cicloalcanos, composições contendo os mesmos e processos de preparação

Info

Publication number
BR0205410A
BR0205410A BR0205410-8A BR0205410A BR0205410A BR 0205410 A BR0205410 A BR 0205410A BR 0205410 A BR0205410 A BR 0205410A BR 0205410 A BR0205410 A BR 0205410A
Authority
BR
Brazil
Prior art keywords
compositions containing
cyclopropylmethyl
aza
cycloalkanes
preparation processes
Prior art date
Application number
BR0205410-8A
Other languages
English (en)
Inventor
Henry Jacobelli
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BR0205410A publication Critical patent/BR0205410A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)

Abstract

"N-(CICLOPROPILMETIL) AZA CICLOALCANOS, COMPOSIçõES CONTENDO OS MESMOS E PROCESSOS DE PREPARAçãO". A presente invenção refere-se a N-(ciclopropilmetil) azacicloalcanos substituídos da seguinte fórmula (I): na qual, independentemente, R~ 1~ é hidrogênio ou halogênio, R~ 2~ é hidrogênio e X é metileno ou etileno, seus sais, as composições farmacêuticas contendo os mesmos, seu uso como medicamentos antidiarréia e processos para sua preparação.
BR0205410-8A 2001-12-21 2002-12-17 N-(ciclopropilmetil) aza cicloalcanos, composições contendo os mesmos e processos de preparação BR0205410A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0116785A FR2833945B1 (fr) 2001-12-21 2001-12-21 N-cyclopropylmethyl-azacycloalcanes, compositions les contenant et procedes de preparation

Publications (1)

Publication Number Publication Date
BR0205410A true BR0205410A (pt) 2004-07-20

Family

ID=8870932

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0205410-8A BR0205410A (pt) 2001-12-21 2002-12-17 N-(ciclopropilmetil) aza cicloalcanos, composições contendo os mesmos e processos de preparação

Country Status (7)

Country Link
US (1) US6787563B2 (pt)
EP (1) EP1321461A1 (pt)
JP (1) JP2003238530A (pt)
BR (1) BR0205410A (pt)
CA (1) CA2414905A1 (pt)
FR (1) FR2833945B1 (pt)
MX (1) MXPA02012190A (pt)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991009594A1 (en) * 1989-12-28 1991-07-11 Virginia Commonwealth University Sigma receptor ligands and the use thereof
FR2713639B1 (fr) * 1993-12-09 1996-08-30 Irj Nouveaux dérivés de 2-arylalkényl-azacycloalkanes ligands aux récepteurs sigma, leur procédé de préparation et leur application en thérapeutique.
FR2760454B1 (fr) * 1997-03-05 1999-04-30 Jouveinal Inst Rech (r) n-(1-cyclopropylmethyl-pyrrolidine-2ylmethyl)-benzamide et son utilite comme antidiarrheique
FR2760455B1 (fr) * 1997-03-05 1999-04-16 Jouveinal Inst Rech (-)e-2-(3,4-dichloro-cinnamyl)-1-cyclopropylmethyl- piperidine, son utilite antidiarrheique

Also Published As

Publication number Publication date
FR2833945A1 (fr) 2003-06-27
MXPA02012190A (es) 2004-10-29
CA2414905A1 (en) 2003-06-21
JP2003238530A (ja) 2003-08-27
FR2833945B1 (fr) 2004-03-12
US20030139448A1 (en) 2003-07-24
US6787563B2 (en) 2004-09-07
EP1321461A1 (en) 2003-06-25

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]